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The map label for this gene is helB [H]

Identifier: 116623328

GI number: 116623328

Start: 5364153

End: 5364833

Strand: Direct

Name: helB [H]

Synonym: Acid_4237

Alternate gene names: 116623328

Gene position: 5364153-5364833 (Clockwise)

Preceding gene: 116623327

Following gene: 116623329

Centisome position: 53.83

GC content: 59.77

Gene sequence:

>681_bases
ATGGCCTACCTGCAGCAGGTGGCCACGATCTTTGCCAAAGATCTGCGCGCCGAACTGCGTACCAAAGAGGCGATCAACGC
GTCGCTCTCCTTCGCGCTTGTTGTGCTGTTGCTGTTCAGCTTCGCGTTCGACCCGAGCGAAGAGACCACGCGCGAAATTT
CGGGCGGGCTGTTGTGGATCGTGTTCGCCTTCGCCGGGACGCTGCTGTTGAATCGCAGCTTCGCGCGCGAGTTGGGTAAC
GATTGCCTGGACGCGCTGATCTCCGCGCCCATCCCCGGCTCCGCGTTGTTCCTGGGAAAGGCGTTCGCGAACTTCGTATT
GGTGATGGCGGTGGAGCTGATCGCGCTGCCCCTCTTCGGCATCTTCTACAACGTGCGCTGGACCTCGCAGTTCTGGCAAC
TGATGCTGGTGGTGGTGCTGGGCACGTGGGCGATGACGGTCACCGGAACGATCTTCAGCGCGCTCACGGTGAATATCCGG
CTGCGCGAAGTGATGCTGCCGATTTTGAATTTCCCGATCCTGATTCCGGCGCTGCTGGGCGCGATGCAGTTGACCTCCGC
GCTGGTGGCGGGCAAGCCAATCACGGCGGATAACGATGCGTGGTTGAAGATGCTGATCGGTTTCGATGTAATGTACACTG
CGGTCTCGGTCTTCCTGGTGGAAACGGTATTGGTAGGTTAA

Upstream 100 bases:

>100_bases
TCGCGCTGCTCAATCGCGGACAGGTGGCGTTTCATGGCCCGTGTACGCCGGAGATGGTGTCCGACCCCGGCTGGGTGTAC
GCGCGATACGGGGAAGGCTG

Downstream 100 bases:

>100_bases
CTATGCGCGATAAAATCCTTTTCCTGATCGGCGCGGCGGCGATTTTGCTGCTGGCGCGCGACATCTACGCAATCATCGGG
CTTCCCGAGGAGAGGAATCA

Product: cytochrome c-type biogenesis protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein HelB [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAYLQQVATIFAKDLRAELRTKEAINASLSFALVVLLLFSFAFDPSEETTREISGGLLWIVFAFAGTLLLNRSFARELGN
DCLDALISAPIPGSALFLGKAFANFVLVMAVELIALPLFGIFYNVRWTSQFWQLMLVVVLGTWAMTVTGTIFSALTVNIR
LREVMLPILNFPILIPALLGAMQLTSALVAGKPITADNDAWLKMLIGFDVMYTAVSVFLVETVLVG

Sequences:

>Translated_226_residues
MAYLQQVATIFAKDLRAELRTKEAINASLSFALVVLLLFSFAFDPSEETTREISGGLLWIVFAFAGTLLLNRSFARELGN
DCLDALISAPIPGSALFLGKAFANFVLVMAVELIALPLFGIFYNVRWTSQFWQLMLVVVLGTWAMTVTGTIFSALTVNIR
LREVMLPILNFPILIPALLGAMQLTSALVAGKPITADNDAWLKMLIGFDVMYTAVSVFLVETVLVG
>Mature_225_residues
AYLQQVATIFAKDLRAELRTKEAINASLSFALVVLLLFSFAFDPSEETTREISGGLLWIVFAFAGTLLLNRSFARELGND
CLDALISAPIPGSALFLGKAFANFVLVMAVELIALPLFGIFYNVRWTSQFWQLMLVVVLGTWAMTVTGTIFSALTVNIRL
REVMLPILNFPILIPALLGAMQLTSALVAGKPITADNDAWLKMLIGFDVMYTAVSVFLVETVLVG

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24731; Mature: 24600

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYLQQVATIFAKDLRAELRTKEAINASLSFALVVLLLFSFAFDPSEETTREISGGLLWI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHH
VFAFAGTLLLNRSFARELGNDCLDALISAPIPGSALFLGKAFANFVLVMAVELIALPLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYNVRWTSQFWQLMLVVVLGTWAMTVTGTIFSALTVNIRLREVMLPILNFPILIPALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMQLTSALVAGKPITADNDAWLKMLIGFDVMYTAVSVFLVETVLVG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYLQQVATIFAKDLRAELRTKEAINASLSFALVVLLLFSFAFDPSEETTREISGGLLWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHH
VFAFAGTLLLNRSFARELGNDCLDALISAPIPGSALFLGKAFANFVLVMAVELIALPLFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFYNVRWTSQFWQLMLVVVLGTWAMTVTGTIFSALTVNIRLREVMLPILNFPILIPALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMQLTSALVAGKPITADNDAWLKMLIGFDVMYTAVSVFLVETVLVG
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1310666 [H]