Click here to switch to the map view.

The map label for this gene is cycZ [H]

Identifier: 116623329

GI number: 116623329

Start: 5364836

End: 5365510

Strand: Direct

Name: cycZ [H]

Synonym: Acid_4238

Alternate gene names: 116623329

Gene position: 5364836-5365510 (Clockwise)

Preceding gene: 116623328

Following gene: 116623330

Centisome position: 53.83

GC content: 62.52

Gene sequence:

>675_bases
ATGCGCGATAAAATCCTTTTCCTGATCGGCGCGGCGGCGATTTTGCTGCTGGCGCGCGACATCTACGCAATCATCGGGCT
TCCCGAGGAGAGGAATCAGGGCATCATCTTCAAGATCATCTTCTTCCACGTGCCGATGGCGATTACCGCGCTCACTTGCG
CCCTGGTAGCCTTCTGCGCGAGCATCGGTTTCCTGGTGACGAAGAACTTCAAGTTCGATGCGATGGCGGTGGCGGTAACA
GAGGTCGGGCTAGCGTTCCTGGCGGGCAATTTGATCACCGGGTCAATCTGGGGACGGGTGGCGTGGGGCATCTGGTGGGC
CTGGGACGCGCGGCTGACCTCGGCCCTGGTCTGCTGGCTGCTGTACGCGGGCTACCTGATGCTGCGGCAGGCGATCGAAG
AGCCGACGCAGCGCGCGACGTTCGCCGCGGTCTTCTCGATCTTCGCATTCATCGATGTGCCGATCGTGATCTTCTCGATC
AAGTGGTGGCGCACGCAGCATCCGCAGCCGGTGTTCTGGGGGGGCGGGAGCATGCCGCACGAGTGGTTCACGCTGTGGGC
GTGGAACGTGCTGGCGATGATGCTGGTGGGTGTGGTGTTCGTCGCGGTCCGGCTGAGGCAGGAAGAGTTCCAGCGCGAGA
TCGATTCGCTGCGCCGCGAGGCGCACGCTCTTTAA

Upstream 100 bases:

>100_bases
CGGCGGATAACGATGCGTGGTTGAAGATGCTGATCGGTTTCGATGTAATGTACACTGCGGTCTCGGTCTTCCTGGTGGAA
ACGGTATTGGTAGGTTAACT

Downstream 100 bases:

>100_bases
CGGAGAAATTTTATGTTCGCATTGTTGCTGCAATCCGCCGAAGATGTGACGCGAGAGATCGCCAGACTTCAGCACGGGTA
TGAGTTTCTGAGCTACGGCC

Product: cytochrome c assembly protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRDKILFLIGAAAILLLARDIYAIIGLPEERNQGIIFKIIFFHVPMAITALTCALVAFCASIGFLVTKNFKFDAMAVAVT
EVGLAFLAGNLITGSIWGRVAWGIWWAWDARLTSALVCWLLYAGYLMLRQAIEEPTQRATFAAVFSIFAFIDVPIVIFSI
KWWRTQHPQPVFWGGGSMPHEWFTLWAWNVLAMMLVGVVFVAVRLRQEEFQREIDSLRREAHAL

Sequences:

>Translated_224_residues
MRDKILFLIGAAAILLLARDIYAIIGLPEERNQGIIFKIIFFHVPMAITALTCALVAFCASIGFLVTKNFKFDAMAVAVT
EVGLAFLAGNLITGSIWGRVAWGIWWAWDARLTSALVCWLLYAGYLMLRQAIEEPTQRATFAAVFSIFAFIDVPIVIFSI
KWWRTQHPQPVFWGGGSMPHEWFTLWAWNVLAMMLVGVVFVAVRLRQEEFQREIDSLRREAHAL
>Mature_224_residues
MRDKILFLIGAAAILLLARDIYAIIGLPEERNQGIIFKIIFFHVPMAITALTCALVAFCASIGFLVTKNFKFDAMAVAVT
EVGLAFLAGNLITGSIWGRVAWGIWWAWDARLTSALVCWLLYAGYLMLRQAIEEPTQRATFAAVFSIFAFIDVPIVIFSI
KWWRTQHPQPVFWGGGSMPHEWFTLWAWNVLAMMLVGVVFVAVRLRQEEFQREIDSLRREAHAL

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=144, Percent_Identity=35.4166666666667, Blast_Score=93, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 25395; Mature: 25395

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKILFLIGAAAILLLARDIYAIIGLPEERNQGIIFKIIFFHVPMAITALTCALVAFCA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SIGFLVTKNFKFDAMAVAVTEVGLAFLAGNLITGSIWGRVAWGIWWAWDARLTSALVCWL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYAGYLMLRQAIEEPTQRATFAAVFSIFAFIDVPIVIFSIKWWRTQHPQPVFWGGGSMPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEECCCCCCH
EWFTLWAWNVLAMMLVGVVFVAVRLRQEEFQREIDSLRREAHAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDKILFLIGAAAILLLARDIYAIIGLPEERNQGIIFKIIFFHVPMAITALTCALVAFCA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
SIGFLVTKNFKFDAMAVAVTEVGLAFLAGNLITGSIWGRVAWGIWWAWDARLTSALVCWL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYAGYLMLRQAIEEPTQRATFAAVFSIFAFIDVPIVIFSIKWWRTQHPQPVFWGGGSMPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCEEEECCCCCCH
EWFTLWAWNVLAMMLVGVVFVAVRLRQEEFQREIDSLRREAHAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]