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The map label for this gene is hutI [H]

Identifier: 116623182

GI number: 116623182

Start: 5199454

End: 5200656

Strand: Reverse

Name: hutI [H]

Synonym: Acid_4089

Alternate gene names: 116623182

Gene position: 5200656-5199454 (Counterclockwise)

Preceding gene: 116623184

Following gene: 116623176

Centisome position: 52.19

GC content: 66.0

Gene sequence:

>1203_bases
TTGACCTTGCATGGTGGAGCGGTGCCGAGGCTCGGAACCGGCCTCAATGACCTCGGCATCATTACCGACGGCGCCGTGCT
GATCCGCAACGGCGTCATTGTGGAGGTCGGATCCTCCCGGCGGGTGGAGAACCTCGCCTCTGCACGCCATGCCGTCGAAA
TCAATGCCGCCGGACGTGTCGTTATGCCCGGCTTCATCGATAGCCACACACACCTCGCATTCCCGCCCGCCGGAGTCTCT
GCCGCCAACCAGGAAACCGCCGCCCGTGCCGTCCGCGCCGCCACCGGGCAGCGCCTCGAACTCCGCACTCGGGCCTACCT
GGAAGCCATGGCCCGCCACGGCACCACCACCGTCGAGATCAAGACCGGTTGCGGTCCCGACGATGCCTGCGAAGCCAAGC
TCCTGCGCCTCCTCGCCGCTGTCCGCCGCGATCCCCTCGAAGTCATAGCCAGTTACCTCTTCCGCCTGCCCCCCGCTATC
GAAGGCGGCGCGCTCCTCGGCGCCGTCGAATGGGCCGCCAACGATCTCCTGCCGAAAATCCGCCGCCGCCGGAGCATCGA
TTTTGCCGACCTGGCCTGGAACGCCGACCCCGTCATGCTCCCATCCTTCGAGCGCTTCCTCGCCGCCGCTCACAAACTCG
GCTTCGCCTGCCGCATCCACGCCGACGGCCCATCCCCCGATTCCGCCGTTGAACTTGCCCTGCGCCATGGTGTCAGCGGC
GTGGACCACCTCGAATACGCAACCGAGGCTCACGCACGCCAGTTGGCCCGCGCCGGAATCGTCACCACCCTTCTCCCCGG
CGGCGCCTTTCACAATGACGGAAAAATTCCACCCGCCCGCGCCTTGATCGATGCCGGCGCCGCCATCGCCCTTGGCACCA
ACTTTAATCCCACTCATTCACCCATGCTCAACATGCAGACCAGCATCGCGCTCGCCTGCTGGCGCCTGCGCATGACGCTC
GAAGAAGCCATCTCCGCCGCTACCATCAACAGCGCCTATGCCCTCCGCTGCGCCGACCGCACCGGCTCTCTCGAACTCGG
AAAATCCGCCGACCTCGTCATCCTCAACGCCCCCGATTACCGCGACCTCTCCACCTGCATCGGCACCAACCTCGTCCACC
TCACCATGAAGCGCGGCAAGTTCATCTACAAGGAAGGCGAAGTCGCCCCCCGCCCCCCCGAAATCATCACCCCACCCCAG
TAG

Upstream 100 bases:

>100_bases
CTTCTTTTCCATAAATTTAAATTGTTAAGACTAGTACTATTGTTACATTGGAATAAGGATTTCCCTGGACTCAATTCTAA
TTCGAGGTGCCCGCTGCCTT

Downstream 100 bases:

>100_bases
CGCCCGCAGACCCTCAGTTTGTATTACTGTGCATCTGTCTGCTCGCAGCCCGCGCACCACAATTTCAATTTGCTGCTCGC
CGCACTGTACTACTGTGCAT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTLHGGAVPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRVVMPGFIDSHTHLAFPPAGVS
AANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEIKTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAI
EGGALLGAVEWAANDLLPKIRRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSG
VDHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHSPMLNMQTSIALACWRLRMTL
EEAISAATINSAYALRCADRTGSLELGKSADLVILNAPDYRDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ

Sequences:

>Translated_400_residues
MTLHGGAVPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRVVMPGFIDSHTHLAFPPAGVS
AANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEIKTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAI
EGGALLGAVEWAANDLLPKIRRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSG
VDHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHSPMLNMQTSIALACWRLRMTL
EEAISAATINSAYALRCADRTGSLELGKSADLVILNAPDYRDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ
>Mature_399_residues
TLHGGAVPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRVVMPGFIDSHTHLAFPPAGVSA
ANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEIKTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAIE
GGALLGAVEWAANDLLPKIRRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSGV
DHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHSPMLNMQTSIALACWRLRMTLE
EAISAATINSAYALRCADRTGSLELGKSADLVILNAPDYRDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=394, Percent_Identity=30.7106598984772, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17555004, Length=424, Percent_Identity=27.122641509434, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 42626; Mature: 42494

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHGGAVPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRV
CCCCCCCCCCCCCCCCCCCEEECCEEEEECCEEEEECCCCHHHHHHHHHHEEEECCCCCE
VMPGFIDSHTHLAFPPAGVSAANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEI
EECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEE
KTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAIEGGALLGAVEWAANDLLPKI
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHH
RRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSG
HHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCC
VDHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHS
CHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCC
PMLNMQTSIALACWRLRMTLEEAISAATINSAYALRCADRTGSLELGKSADLVILNAPDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCEEEECCCCC
RDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ
CHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLHGGAVPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRV
CCCCCCCCCCCCCCCCCCEEECCEEEEECCEEEEECCCCHHHHHHHHHHEEEECCCCCE
VMPGFIDSHTHLAFPPAGVSAANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEI
EECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCEEEEE
KTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAIEGGALLGAVEWAANDLLPKI
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHH
RRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSG
HHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCC
VDHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHS
CHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCCC
PMLNMQTSIALACWRLRMTLEEAISAATINSAYALRCADRTGSLELGKSADLVILNAPDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCEEEECCCCC
RDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ
CHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA