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The map label for this gene is dgoT [H]

Identifier: 116623074

GI number: 116623074

Start: 5044832

End: 5046127

Strand: Direct

Name: dgoT [H]

Synonym: Acid_3978

Alternate gene names: 116623074

Gene position: 5044832-5046127 (Clockwise)

Preceding gene: 116623073

Following gene: 116623075

Centisome position: 50.62

GC content: 64.89

Gene sequence:

>1296_bases
TTGGTAATGAGCAGCAGACCCCAGATCGCGGGCTCCGCCATCGCGGCGCCCGCGGCATTCCCCCCGGCCGAATCCGCGGC
GCGCCGTTGGACCGTAATCGGGCTCCTCAGCCTGGGAATGATCATCGCCTACGCCTCGCGCTCCAATCTCTCCGTCGCGC
TGGTCACCAAGGATTTCATCCGCAGCTTTCAGCTCTCCGACACCGATCGCGGTCTCCTCAATTCCGCCTTTTTCTGGGCC
TACGCCGCGCTGCAAATTCCCGCCGGCTGGGTGGTGGATCGCTATGGCGTCAAGTGGCCTTACGCGATCAGCTTCCTGTT
CTGGTGCCTTGCCTCGGCCGGCACCGCGCTCGCAGGCACCGTTGGCCAGTTGATCGCGCTGCGCATTCTGCTCGGCATGG
GCGAAAGCGTGGTCGCGCCCGCCAGCTACCGCTGGATCCGCCTCAACTTCGCCGAGCGCCAGCGCGGCCTCGCCGTCGGC
CTCTACATGACCGGCACCAAGATCGGCCCCGCCATCGGCACGCCGCTCGCCGCCTGGCTGATTCTCAATCACGATTGGCG
CGCCATGTTCATCATGGTCGGCCTGGGCGGCTTAATCTGGCTGATCCCGTGGATGATTCTGGTCAAGGATACCCAGGCCG
CGCCCAAACTCGCCGCCGCCGCAGCTCCGCCGCGGACCGTCTCCTTCGCCCGCGTGCTGGCCAGCCCCGTCACCTGGGGC
ACCGTGATCGCCACCTTCAGCTACATGTACTTCGTGTACTTCTGCATGACCTGGATGCCCGCCTATTTCATGGAGCGCCG
CCACCTCTCGCTTTCCCAGATGGGCCTCTACACCTTCTTCAGTTTCGGCGGCATGGCGATTGTTGCCGCGGGCGCCGGCT
GGGCCGCCGATCTGTTAATCGGCCGCGGCGGTAACCCGGTCACCGTCCGAAAGTGGTTCACCATCGCCGGCTTTGCCGTG
GCCTGCACGGAATTGATCGGTTCTCAATCGTCCTCCGTACAAGTGGCGCTCGTCTTCTCCGTGGTATCGCTCTCCGGCCT
CGGCCTCGCCACCGCGAATTACTGGGCGCTCACCCAGACCCTGATCCCCGCGTGGGCCATCGGCCGCATCTCCGGCGTGC
AGAATTGCGCCGCCAGCATCGCCGGTATCGTCGCCCCCATCCTCACCGGCTGGCTCAAACAGAAAACCGGAAACTACGAA
GCTCCCATGTTCGCCTGTGCCGTCTTCCTCGTCCTGGGCGTGCTCTCCTACATCTTCATGGTCAAAGAGCGCTACGCGCC
GGAGATGGCGTCGTGA

Upstream 100 bases:

>100_bases
TCTTCGGCGGCCCGCAGACCAGCCTCAACAGCAGCACCTTCGGCGTCATTTCGAGCCAGGCCAATTCGCCGCGCCAGATG
CAAGGCGGGTTAAAGTTGTA

Downstream 100 bases:

>100_bases
GTTCGCAGGCGGAGACCATCCGCCGCAAGCCGCGCCGCCTGGCCACGGAGCTGGTGGATTCGCTCTCCGAACAGATCCGC
GGCCGGGCCCTCAAACCCGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MVMSSRPQIAGSAIAAPAAFPPAESAARRWTVIGLLSLGMIIAYASRSNLSVALVTKDFIRSFQLSDTDRGLLNSAFFWA
YAALQIPAGWVVDRYGVKWPYAISFLFWCLASAGTALAGTVGQLIALRILLGMGESVVAPASYRWIRLNFAERQRGLAVG
LYMTGTKIGPAIGTPLAAWLILNHDWRAMFIMVGLGGLIWLIPWMILVKDTQAAPKLAAAAAPPRTVSFARVLASPVTWG
TVIATFSYMYFVYFCMTWMPAYFMERRHLSLSQMGLYTFFSFGGMAIVAAGAGWAADLLIGRGGNPVTVRKWFTIAGFAV
ACTELIGSQSSSVQVALVFSVVSLSGLGLATANYWALTQTLIPAWAIGRISGVQNCAASIAGIVAPILTGWLKQKTGNYE
APMFACAVFLVLGVLSYIFMVKERYAPEMAS

Sequences:

>Translated_431_residues
MVMSSRPQIAGSAIAAPAAFPPAESAARRWTVIGLLSLGMIIAYASRSNLSVALVTKDFIRSFQLSDTDRGLLNSAFFWA
YAALQIPAGWVVDRYGVKWPYAISFLFWCLASAGTALAGTVGQLIALRILLGMGESVVAPASYRWIRLNFAERQRGLAVG
LYMTGTKIGPAIGTPLAAWLILNHDWRAMFIMVGLGGLIWLIPWMILVKDTQAAPKLAAAAAPPRTVSFARVLASPVTWG
TVIATFSYMYFVYFCMTWMPAYFMERRHLSLSQMGLYTFFSFGGMAIVAAGAGWAADLLIGRGGNPVTVRKWFTIAGFAV
ACTELIGSQSSSVQVALVFSVVSLSGLGLATANYWALTQTLIPAWAIGRISGVQNCAASIAGIVAPILTGWLKQKTGNYE
APMFACAVFLVLGVLSYIFMVKERYAPEMAS
>Mature_431_residues
MVMSSRPQIAGSAIAAPAAFPPAESAARRWTVIGLLSLGMIIAYASRSNLSVALVTKDFIRSFQLSDTDRGLLNSAFFWA
YAALQIPAGWVVDRYGVKWPYAISFLFWCLASAGTALAGTVGQLIALRILLGMGESVVAPASYRWIRLNFAERQRGLAVG
LYMTGTKIGPAIGTPLAAWLILNHDWRAMFIMVGLGGLIWLIPWMILVKDTQAAPKLAAAAAPPRTVSFARVLASPVTWG
TVIATFSYMYFVYFCMTWMPAYFMERRHLSLSQMGLYTFFSFGGMAIVAAGAGWAADLLIGRGGNPVTVRKWFTIAGFAV
ACTELIGSQSSSVQVALVFSVVSLSGLGLATANYWALTQTLIPAWAIGRISGVQNCAASIAGIVAPILTGWLKQKTGNYE
APMFACAVFLVLGVLSYIFMVKERYAPEMAS

Specific function: Intake of galactonate into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=456, Percent_Identity=24.780701754386, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI9945322, Length=412, Percent_Identity=26.4563106796117, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI21322234, Length=430, Percent_Identity=24.8837209302326, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI154350196, Length=392, Percent_Identity=24.234693877551, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI9966811, Length=431, Percent_Identity=24.1299303944316, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI223718438, Length=413, Percent_Identity=23.4866828087167, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87082320, Length=422, Percent_Identity=27.2511848341232, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI2367379, Length=408, Percent_Identity=28.1862745098039, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1789515, Length=435, Percent_Identity=23.9080459770115, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789152, Length=447, Percent_Identity=24.1610738255034, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI2367193, Length=189, Percent_Identity=31.7460317460317, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17535049, Length=434, Percent_Identity=23.963133640553, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554148, Length=389, Percent_Identity=22.6221079691517, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554962, Length=325, Percent_Identity=22.7692307692308, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=400, Percent_Identity=25, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=400, Percent_Identity=25, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24654215, Length=467, Percent_Identity=25.4817987152034, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639764, Length=406, Percent_Identity=26.3546798029557, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922400, Length=462, Percent_Identity=25.5411255411255, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24583789, Length=382, Percent_Identity=25.130890052356, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24584153, Length=351, Percent_Identity=23.3618233618234, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI45550460, Length=440, Percent_Identity=22.5, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648416, Length=431, Percent_Identity=23.4338747099768, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21356189, Length=431, Percent_Identity=23.4338747099768, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI20129235, Length=431, Percent_Identity=22.969837587007, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI62484226, Length=386, Percent_Identity=22.5388601036269, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20130167, Length=406, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573299, Length=439, Percent_Identity=23.0068337129841, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641682, Length=432, Percent_Identity=24.7685185185185, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24655255, Length=411, Percent_Identity=21.1678832116788, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920686, Length=381, Percent_Identity=22.0472440944882, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573708, Length=410, Percent_Identity=22.1951219512195, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28573707, Length=410, Percent_Identity=22.1951219512195, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24580790, Length=384, Percent_Identity=23.9583333333333, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46431; Mature: 46431

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSSRPQIAGSAIAAPAAFPPAESAARRWTVIGLLSLGMIIAYASRSNLSVALVTKDFI
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
RSFQLSDTDRGLLNSAFFWAYAALQIPAGWVVDRYGVKWPYAISFLFWCLASAGTALAGT
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHH
VGQLIALRILLGMGESVVAPASYRWIRLNFAERQRGLAVGLYMTGTKIGPAIGTPLAAWL
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHCCCCEEEEEEECCCCCCHHCCHHHHHH
ILNHDWRAMFIMVGLGGLIWLIPWMILVKDTQAAPKLAAAAAPPRTVSFARVLASPVTWG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCCHHH
TVIATFSYMYFVYFCMTWMPAYFMERRHLSLSQMGLYTFFSFGGMAIVAAGAGWAADLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHEE
GRGGNPVTVRKWFTIAGFAVACTELIGSQSSSVQVALVFSVVSLSGLGLATANYWALTQT
ECCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHH
LIPAWAIGRISGVQNCAASIAGIVAPILTGWLKQKTGNYEAPMFACAVFLVLGVLSYIFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VKERYAPEMAS
HHHHCCCCCCC
>Mature Secondary Structure
MVMSSRPQIAGSAIAAPAAFPPAESAARRWTVIGLLSLGMIIAYASRSNLSVALVTKDFI
CCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHH
RSFQLSDTDRGLLNSAFFWAYAALQIPAGWVVDRYGVKWPYAISFLFWCLASAGTALAGT
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHCCCHHHHH
VGQLIALRILLGMGESVVAPASYRWIRLNFAERQRGLAVGLYMTGTKIGPAIGTPLAAWL
HHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHCCCCEEEEEEECCCCCCHHCCHHHHHH
ILNHDWRAMFIMVGLGGLIWLIPWMILVKDTQAAPKLAAAAAPPRTVSFARVLASPVTWG
EECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCCHHH
TVIATFSYMYFVYFCMTWMPAYFMERRHLSLSQMGLYTFFSFGGMAIVAAGAGWAADLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHEE
GRGGNPVTVRKWFTIAGFAVACTELIGSQSSSVQVALVFSVVSLSGLGLATANYWALTQT
ECCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHH
LIPAWAIGRISGVQNCAASIAGIVAPILTGWLKQKTGNYEAPMFACAVFLVLGVLSYIFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
VKERYAPEMAS
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]