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The map label for this gene is yidJ [H]

Identifier: 116623047

GI number: 116623047

Start: 5001501

End: 5003051

Strand: Direct

Name: yidJ [H]

Synonym: Acid_3951

Alternate gene names: 116623047

Gene position: 5001501-5003051 (Clockwise)

Preceding gene: 116623041

Following gene: 116623048

Centisome position: 50.19

GC content: 64.09

Gene sequence:

>1551_bases
ATGTCCGACACGCTCAACCGACGCAGCTTCCTCGCAAGTACCGCGGGACTGGGGGCCGCCGCCGCGCAGACTCCGGGACC
CGGTGTGCGCCCCAATATTCTGCACATCATGACCGACCAGCAGCAGTGGGCCACCATCGCCGGACGCTCCGGCTGCCGCA
CTCCGAATATTGACCGGCTGGCCAGCCAGGGGATGCTGTTCGAACGCAGCTATACACCGTCGGCTGTGTGCTGCCCCGCG
CGCGCCATGCTGTTGAGCGGGGCATACCACTGGCACAACGGCGTGTACAACCAGGTGCATTCGCCGCCTTCCGTACATCG
CGATATGAACGCGGACGTGGTGCTCTACTCGCAGCGCCTGCGGGAAGCGGGGTATCGCCTGGGCTACACCGGCAAGTGGC
ACGCCAGCTATTTGCGCACGCCGCTCGATTTCGGCTTCCACGAGATCGCGGGCGTGGCCGGCTGCGATCCGGAACTGCTA
AAGAAGATCGACTTGAATCCCGATCGTGTCCCACGGATCACCGAGCCGCTGCGCACCACCCAGCAGCGCATGATGCGGTG
GCCGGGATCCGAGCCCTTCGTGATGTGGGGCTATCGCGAGGGCCCGGAGGAATCCACGCCCGAGTATCGCATCGCCGAGA
TGGCATCGCGGATGATGAAACGCTTTGCCAAAGGCGAGCAGCCCTGGCACCTGGAAGTCCACTTCGTGGAACCGCACGAT
CCCTATATGCCGCTGAAGCAATACCTCGACCGCTACGATCCTCGCTCGATCCCGGTACCGAAGAGCTTCGCCGATACGTT
CGCGGGCAAGCCCGGGCTGCACCGGCGCGAATCGGAAACCTGGGGCAAAGTCACGGAGGACGACGTACGCCAGAGCCGCG
CGCATTATTACGCGTATGCCGAGCAGCTCGACGCGCAGATCGGCCGTGTCCTCAAAGCGCTCGACGAGACCGGGCAGGCC
GATCGCACGCTGGTCGCTTTCACCGCGGATCACGGCGACATGGTGGGCGCGCACCGCATGTGGATCAAGGGTTGGCTGCC
ATACGAGGAATGCTATCGGGTACCGATGATCGTGCGCTGGCCGGGGCACGTGCAGGCCGGGTCGAAATCCTCGAAGCTGG
TGCAGACGCACGATCTGGGACACACCTATCTGGCGGCGGCCGGGGCGCGTTCCCTGCCCTTCCCGGATGGCGCATCGCTC
GCACCCCTTTTCGCCGACCCGAGGCGCAAGGACTGGCGTGACGATATCCTGTGCGCCTACTACGGCGGCGAGTACCTCTA
CACGCAGCGCATTGCGATCACCGACCGCTTCAAGTATGTCTTCAACGGCTTCGACTACGACGAGATGTACGACCTGGAGC
GCGATCCCGACGAGATGCGCAACGTGGTCGCGGATTCGGAGTACGCGCGATTTACCGGCGATATGCAGGCGCGGATGTAC
GAACTGATGGCCCGCTTCCACGATCCATACGGCGATTCCCCCGAAGGCACGAAAGGCGATCGCTATTGTGCCGCGAGGTA
CTTGCCCAGGGGGAAGCGCATTCCCGCTTGA

Upstream 100 bases:

>100_bases
GCGGCGATGAGGATTGGGATTTTCCATAAATTGCTTGCAGTATATCGAGCTTCCAGCTCGCGCGCATGGGTGATCTGAGG
GTGATCTAATAAGGAGCGTC

Downstream 100 bases:

>100_bases
ATTGCGCCAGAATAGGGAGAGCACGGAGGGTGTATTGGTCGCTCGTCTGTTCCTTGTCGTAACTGCGATCGGCCTTGGCT
CGGCCGCGGAGAAAGCTGTC

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MSDTLNRRSFLASTAGLGAAAAQTPGPGVRPNILHIMTDQQQWATIAGRSGCRTPNIDRLASQGMLFERSYTPSAVCCPA
RAMLLSGAYHWHNGVYNQVHSPPSVHRDMNADVVLYSQRLREAGYRLGYTGKWHASYLRTPLDFGFHEIAGVAGCDPELL
KKIDLNPDRVPRITEPLRTTQQRMMRWPGSEPFVMWGYREGPEESTPEYRIAEMASRMMKRFAKGEQPWHLEVHFVEPHD
PYMPLKQYLDRYDPRSIPVPKSFADTFAGKPGLHRRESETWGKVTEDDVRQSRAHYYAYAEQLDAQIGRVLKALDETGQA
DRTLVAFTADHGDMVGAHRMWIKGWLPYEECYRVPMIVRWPGHVQAGSKSSKLVQTHDLGHTYLAAAGARSLPFPDGASL
APLFADPRRKDWRDDILCAYYGGEYLYTQRIAITDRFKYVFNGFDYDEMYDLERDPDEMRNVVADSEYARFTGDMQARMY
ELMARFHDPYGDSPEGTKGDRYCAARYLPRGKRIPA

Sequences:

>Translated_516_residues
MSDTLNRRSFLASTAGLGAAAAQTPGPGVRPNILHIMTDQQQWATIAGRSGCRTPNIDRLASQGMLFERSYTPSAVCCPA
RAMLLSGAYHWHNGVYNQVHSPPSVHRDMNADVVLYSQRLREAGYRLGYTGKWHASYLRTPLDFGFHEIAGVAGCDPELL
KKIDLNPDRVPRITEPLRTTQQRMMRWPGSEPFVMWGYREGPEESTPEYRIAEMASRMMKRFAKGEQPWHLEVHFVEPHD
PYMPLKQYLDRYDPRSIPVPKSFADTFAGKPGLHRRESETWGKVTEDDVRQSRAHYYAYAEQLDAQIGRVLKALDETGQA
DRTLVAFTADHGDMVGAHRMWIKGWLPYEECYRVPMIVRWPGHVQAGSKSSKLVQTHDLGHTYLAAAGARSLPFPDGASL
APLFADPRRKDWRDDILCAYYGGEYLYTQRIAITDRFKYVFNGFDYDEMYDLERDPDEMRNVVADSEYARFTGDMQARMY
ELMARFHDPYGDSPEGTKGDRYCAARYLPRGKRIPA
>Mature_515_residues
SDTLNRRSFLASTAGLGAAAAQTPGPGVRPNILHIMTDQQQWATIAGRSGCRTPNIDRLASQGMLFERSYTPSAVCCPAR
AMLLSGAYHWHNGVYNQVHSPPSVHRDMNADVVLYSQRLREAGYRLGYTGKWHASYLRTPLDFGFHEIAGVAGCDPELLK
KIDLNPDRVPRITEPLRTTQQRMMRWPGSEPFVMWGYREGPEESTPEYRIAEMASRMMKRFAKGEQPWHLEVHFVEPHDP
YMPLKQYLDRYDPRSIPVPKSFADTFAGKPGLHRRESETWGKVTEDDVRQSRAHYYAYAEQLDAQIGRVLKALDETGQAD
RTLVAFTADHGDMVGAHRMWIKGWLPYEECYRVPMIVRWPGHVQAGSKSSKLVQTHDLGHTYLAAAGARSLPFPDGASLA
PLFADPRRKDWRDDILCAYYGGEYLYTQRIAITDRFKYVFNGFDYDEMYDLERDPDEMRNVVADSEYARFTGDMQARMYE
LMARFHDPYGDSPEGTKGDRYCAARYLPRGKRIPA

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=452, Percent_Identity=27.4336283185841, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI39930577, Length=483, Percent_Identity=21.9461697722567, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI31742482, Length=459, Percent_Identity=25.7080610021786, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI4504061, Length=498, Percent_Identity=22.4899598393574, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI58743319, Length=473, Percent_Identity=23.8900634249471, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI157266309, Length=478, Percent_Identity=23.8493723849372, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4557659, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI262118210, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38569405, Length=385, Percent_Identity=24.9350649350649, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI38569407, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI59797060, Length=315, Percent_Identity=24.7619047619048, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI5360208, Length=149, Percent_Identity=28.8590604026846, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790112, Length=468, Percent_Identity=29.9145299145299, Blast_Score=179, Evalue=6e-46,
Organism=Drosophila melanogaster, GI24647401, Length=417, Percent_Identity=25.8992805755396, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24666109, Length=313, Percent_Identity=27.1565495207668, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 58915; Mature: 58784

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTLNRRSFLASTAGLGAAAAQTPGPGVRPNILHIMTDQQQWATIAGRSGCRTPNIDRL
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCHHHH
ASQGMLFERSYTPSAVCCPARAMLLSGAYHWHNGVYNQVHSPPSVHRDMNADVVLYSQRL
HHCCCEEECCCCCCHHHHHHHHHHHHCCHHHHCCHHHHCCCCCHHHCCCCCCEEHHHHHH
REAGYRLGYTGKWHASYLRTPLDFGFHEIAGVAGCDPELLKKIDLNPDRVPRITEPLRTT
HHCCCCCCCCCCCHHHHHCCCHHCCHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHH
QQRMMRWPGSEPFVMWGYREGPEESTPEYRIAEMASRMMKRFAKGEQPWHLEVHFVEPHD
HHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
PYMPLKQYLDRYDPRSIPVPKSFADTFAGKPGLHRRESETWGKVTEDDVRQSRAHYYAYA
CCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EQLDAQIGRVLKALDETGQADRTLVAFTADHGDMVGAHRMWIKGWLPYEECYRVPMIVRW
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHCCCCEEEEC
PGHVQAGSKSSKLVQTHDLGHTYLAAAGARSLPFPDGASLAPLFADPRRKDWRDDILCAY
CCCCCCCCCCCCEEEHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
YGGEYLYTQRIAITDRFKYVFNGFDYDEMYDLERDPDEMRNVVADSEYARFTGDMQARMY
ECCCEEEEEEEEHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
ELMARFHDPYGDSPEGTKGDRYCAARYLPRGKRIPA
HHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDTLNRRSFLASTAGLGAAAAQTPGPGVRPNILHIMTDQQQWATIAGRSGCRTPNIDRL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCCHHHH
ASQGMLFERSYTPSAVCCPARAMLLSGAYHWHNGVYNQVHSPPSVHRDMNADVVLYSQRL
HHCCCEEECCCCCCHHHHHHHHHHHHCCHHHHCCHHHHCCCCCHHHCCCCCCEEHHHHHH
REAGYRLGYTGKWHASYLRTPLDFGFHEIAGVAGCDPELLKKIDLNPDRVPRITEPLRTT
HHCCCCCCCCCCCHHHHHCCCHHCCHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHH
QQRMMRWPGSEPFVMWGYREGPEESTPEYRIAEMASRMMKRFAKGEQPWHLEVHFVEPHD
HHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCC
PYMPLKQYLDRYDPRSIPVPKSFADTFAGKPGLHRRESETWGKVTEDDVRQSRAHYYAYA
CCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EQLDAQIGRVLKALDETGQADRTLVAFTADHGDMVGAHRMWIKGWLPYEECYRVPMIVRW
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHCCCCEEEEC
PGHVQAGSKSSKLVQTHDLGHTYLAAAGARSLPFPDGASLAPLFADPRRKDWRDDILCAY
CCCCCCCCCCCCEEEHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
YGGEYLYTQRIAITDRFKYVFNGFDYDEMYDLERDPDEMRNVVADSEYARFTGDMQARMY
ECCCEEEEEEEEHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
ELMARFHDPYGDSPEGTKGDRYCAARYLPRGKRIPA
HHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Sulfuric ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]