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The map label for this gene is nagB [H]

Identifier: 116623011

GI number: 116623011

Start: 4949501

End: 4950229

Strand: Reverse

Name: nagB [H]

Synonym: Acid_3915

Alternate gene names: 116623011

Gene position: 4950229-4949501 (Counterclockwise)

Preceding gene: 116623015

Following gene: 116623010

Centisome position: 49.67

GC content: 68.59

Gene sequence:

>729_bases
GTGCGCGTTTACCCCGATGGCATCGAAGCCGGCGCCGCCGGCGCGCAAATCGCCGCCGCCATCATCGCCGAAACCATCGC
GCGCGACGGCAAGGCCGCCGTGGTCTTCGCCTCCGCCGTGTCGCAGGATCCCTTTCTCGCCGCCCTCCGCGAGCAGCCCA
TCGAGTGGCCGCGCCTCGCCGCTTTCCACATGGACGAGTACGCGGGAATGGCGGCCGACCATCCAGCCTCCTTCCGCCGC
TTTCTCCGCGATCGCCTCTTCGACCACGTGCCGGTGGCCGCGTTCCACCAGCTCGATGCCGAAGCAGCCGATGCCAATGC
CGAATGCGAGCGCTACGCCGCCCTGCTCCGCGCATCCAACCCTTGCCTGGTGATCATGGGCATCGGCGAAAACGGGCACC
TCGCCTTCATCGATCCCCCGGTCTGCGATTTCCACGATCCCCGCGACGTCCGCCCTGTCGAACTCGACGATGTCTGCCGT
ATGCAGCAGGTCCACGATGGCGCCTTCGCCCGCCTCGAGGACGTCCCCGCGCGCGCACTCTCGCTCACCGTGCCATTCTT
TCTCCGCGTCCCGCGCGCGCTGGTTTTCGTCAACGGCCCCCATAAGAGTGCGGCGGTCCACGCCGCGCTCGATGGCCCGA
TCACGGAAGCCTGCCCCGCCTCCGCTCTTCGCCGGCATCCCTCCGCGGTACTCTTCCTGGACCCTCCCGCCGCCAGCTTG
CTCTCGTAA

Upstream 100 bases:

>100_bases
CAGAAGCAGCGCGAGACAGAGAGTCTGCATGCTGCCCAAATCATCGCATGCTAGAATTCAGGCTTCAACAAACATGACTT
TTACCCGTGACAACCTTGCC

Downstream 100 bases:

>100_bases
TGTAAGAAATCTTGCGGAACCGCGCTAAACTCTTTACAGCGAGGGGATCACCTAACTTGTACCGTTACTCCGTTCTGGTT
CTTCTGTTCGGCGCCGCACA

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRVYPDGIEAGAAGAQIAAAIIAETIARDGKAAVVFASAVSQDPFLAALREQPIEWPRLAAFHMDEYAGMAADHPASFRR
FLRDRLFDHVPVAAFHQLDAEAADANAECERYAALLRASNPCLVIMGIGENGHLAFIDPPVCDFHDPRDVRPVELDDVCR
MQQVHDGAFARLEDVPARALSLTVPFFLRVPRALVFVNGPHKSAAVHAALDGPITEACPASALRRHPSAVLFLDPPAASL
LS

Sequences:

>Translated_242_residues
MRVYPDGIEAGAAGAQIAAAIIAETIARDGKAAVVFASAVSQDPFLAALREQPIEWPRLAAFHMDEYAGMAADHPASFRR
FLRDRLFDHVPVAAFHQLDAEAADANAECERYAALLRASNPCLVIMGIGENGHLAFIDPPVCDFHDPRDVRPVELDDVCR
MQQVHDGAFARLEDVPARALSLTVPFFLRVPRALVFVNGPHKSAAVHAALDGPITEACPASALRRHPSAVLFLDPPAASL
LS
>Mature_242_residues
MRVYPDGIEAGAAGAQIAAAIIAETIARDGKAAVVFASAVSQDPFLAALREQPIEWPRLAAFHMDEYAGMAADHPASFRR
FLRDRLFDHVPVAAFHQLDAEAADANAECERYAALLRASNPCLVIMGIGENGHLAFIDPPVCDFHDPRDVRPVELDDVCR
MQQVHDGAFARLEDVPARALSLTVPFFLRVPRALVFVNGPHKSAAVHAALDGPITEACPASALRRHPSAVLFLDPPAASL
LS

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=188, Percent_Identity=28.7234042553192, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI19923881, Length=192, Percent_Identity=26.0416666666667, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786893, Length=192, Percent_Identity=28.125, Blast_Score=95, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17554876, Length=188, Percent_Identity=28.7234042553192, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24581960, Length=192, Percent_Identity=27.6041666666667, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920764, Length=192, Percent_Identity=27.6041666666667, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 26072; Mature: 26072

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYPDGIEAGAAGAQIAAAIIAETIARDGKAAVVFASAVSQDPFLAALREQPIEWPRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHCCCCCHHHH
AFHMDEYAGMAADHPASFRRFLRDRLFDHVPVAAFHQLDAEAADANAECERYAALLRASN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCHHHHHHHHHHHCCC
PCLVIMGIGENGHLAFIDPPVCDFHDPRDVRPVELDDVCRMQQVHDGAFARLEDVPARAL
CEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHH
SLTVPFFLRVPRALVFVNGPHKSAAVHAALDGPITEACPASALRRHPSAVLFLDPPAASL
HHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHCCCCEEEEECCCHHHH
LS
CC
>Mature Secondary Structure
MRVYPDGIEAGAAGAQIAAAIIAETIARDGKAAVVFASAVSQDPFLAALREQPIEWPRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHCCCCCHHHH
AFHMDEYAGMAADHPASFRRFLRDRLFDHVPVAAFHQLDAEAADANAECERYAALLRASN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHCCCCHHHHHHHHHHHCCC
PCLVIMGIGENGHLAFIDPPVCDFHDPRDVRPVELDDVCRMQQVHDGAFARLEDVPARAL
CEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCHHHH
SLTVPFFLRVPRALVFVNGPHKSAAVHAALDGPITEACPASALRRHPSAVLFLDPPAASL
HHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHCCCCEEEEECCCHHHH
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA