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The map label for this gene is macB [H]

Identifier: 116623015

GI number: 116623015

Start: 4952842

End: 4955583

Strand: Reverse

Name: macB [H]

Synonym: Acid_3919

Alternate gene names: 116623015

Gene position: 4955583-4952842 (Counterclockwise)

Preceding gene: 116623016

Following gene: 116623011

Centisome position: 49.73

GC content: 62.73

Gene sequence:

>2742_bases
GTGACCGGCGTGCTGCGACGGCTGAGGTATTTGATAGGAAGCGCCCGGCGCAGCGAGGCGCTCCGTGAGGAAATGGAACT
CCACCTTGCGGAGAAAGCCTCGGAACTCGAAGCCGACGGAATGACGGCGGAGCATGCCCGGGTGGAAGCGCGCCGGCGGT
TTGGCAATCTCGGACAGAAGCAGGAAGAGTCACGGGAGATTTGGATGACACGGTTTCTTTCGGAACTTGTACAGGATATC
CGCTACGGCTGTCGCACACTCTCCGGCAACAAGGCATTCAGCGCCCTGGCGGTCCTGTCGCTGGCGCTCGGCATCGGGGC
CAACACTGCGATATTCAGCCTCATGGAGTCAATTCTGTTGCGTTCGCTGCCGGTGGCCGATCCCGAGTCGCTGGTGGTTT
TGAATTGGCATAGCCGGACGCCCAAAGACGGCGACAAGGAATCGGTCCACGTCATGCACGGGCTGCAGGGCATGTTCTGG
CCAGGCAAGAAGGGCGACATGGTCACCGGAATCTTTCCGTACCGCGCGTTCGAGACCCTGCGCGAGGAGAATCCGGTATT
CTCCACACTCTTCGGCTACGTCAACGGACGCAATCGCACCCTGGCCGTTCGCGGGCAGGCCATGAACGCCAGCACCGAGT
ACGTCACTGGCGAATATTTTCGCGGGTTGGCCGTATCGCCGGCCGCGGGACGTCTGATCGAATCCGAAGACGACCGCCCC
GGCGCCGCGCCGGTGGCCGTCGTCAGTTTCGCGACAGGTCAAAATCGCTTTGGAGGGCCGTCGAATGCGATTGGACAGTC
GATTCTCGTCGATAGCGTGCCCTTCACGGTGATCGGGGTCGCGCCGCCGGAATTCTTTGGAGTAGATCCAGCGGCGGCGC
CGGAGGTCTACCTTCCGTTGCACGCGAATCTGCTTGTAGACGGCGCCCGGGCGGCTCGTATCTATGGCGACGAAAACTTC
TACTGGATGGAAATGATGGGCCGCCTGCGCCCCGGCGTAAGCATGGCCCAGGCACAGGCAATGCTGGCTCCCCGGTTTCA
TCAGTGGGTTGCCACCACCGCGAGCACCGATGGCGAGCGCGCCAAACTGCCGGCGCTGATTCTGAATCCAGGCGCCGCCG
GTCTGGGTAGCTTGCGCCGCGAGTATTCCAAGCCTCTGTATGTGCTGCTGACCATGGTGGCGTTGATCCTTGCGATCACG
TGCGCGAACATCGCCAATCTGCTGCTGGCAAGATCCGCCGCGCGGCGCCGCGAAATGGCTGTCCGGCTCAGCCTGGGCGC
GGGAAGGCTGCGCATCGTGCGGCAGATGCTGACCGAGAGTGTGCTGCTGGCATCGCTCGGCGGAGCATTCGGTGTGTTGT
TTGCGGTCTGGGGAATGCGAACCCTGACGTTTCTGCTCTCCAGCGGGCAGAGGAATGTTACGCTGCACGCGGAATTGAAC
TGGAGCGTGCTGGGCGTTACGGCGGCGCTCTCCGTAGTCTGCGGCCTGTTATTCGGCCTCGCTCCGGCGATTCAATCTAC
GCGTCCGGACGTCATGCCCGCGCTAAAGAATGGCCGCGGGGGCGGACCGCGCCGCCGGGCGCAGCACGTTCTGGTGGTCG
GCCAAATTGCGACCTCTTTTCTCATCCTGGTCGCTGCCGGTCTGTTTGTCCGGACACTCAACAACCTGCACTCGGTCCAG
CTGGGATACGCTCGCGAGAACATCCTGCTGTTCTCGCTGAATGCCCGTCAGGCCGGCCATCGCGACCCGGAGATCACCGC
TTTTTACGAGGACCTGCGCAAGCGCCTCGAATCGATTCCCGGAGTGAGCAGTGCGACGCTTTCGCACTCCTCGCTCATCG
ACGCCGGCTTCGCCGGGCCGGCGATCAGGGGCGAAATGAAGATCGGCGCTGTGACTGTCGATGACGCAGGCGTGCTGGCG
GCGGGACCGCGTTTCCTAACCACGATGCAGATTCCAATCCTGGCCGGACGTGAGATTGACGAGCGCGACCAGCGGGGCTC
CATGCCGGTCGCAGTGATCAGCGAGGAGCTGGCGCGGACTTACTTTGGGGATGAAAATCCGGTGGGCCGGCGCATCACAT
TAGTGGACGAGAAGCGAGAACTCGAAATCATCGGCGTGTCGGGTAACCTGCGGTACGGCGGTCTGAAAGAGGCAGAAGAG
AGCTCGATGACCATGTTCGTAGCGGCCAGCCAGATTTCTCCGGACCGAATGACCTACGCGCTGCACACCGCGGGTGATCC
GCTGAGGTATGTCAAGAGTGTGCATGAGATCGTGCGGGAAGCAGACTCCCGCATACCCGTTACGAACGTGGCCACACAGG
CCGCGGAAATCGATCGGACGATCAACCGGGAGATCATGTTCGCGAAACTATGCACAGGATTCGCGGTTCTGGCTCTCCTG
ATGGCGTGCGTGGGGCTCTACGGAACCATCTCGTACAACGTCGCGCGGCAGGTCGGCGAGATCGGTATCCGTATGGCCCT
GGGCGCGCAGCGCGGTGCGGTCGTATGGATGGTGCTCAGCCGCGTTCTACTGCTGGCGGCGGTGGGACTCGCAATCAGCG
TGCCGGCCGCTTTGATCGCGTCCCGGCTGATCAAGTCGTTTCTGTTCGAGACCCGGCCCAATGACCCGGCAACCCTGGTT
CTGGCCGGTGTCGTCCTCCTGAGCGCCGTGATTCTCGCCGGCTATGCGCCGGCACGGCGGGCATCCCGAATTGATCCGCT
GACGGCTCTCCGGCACGATTAG

Upstream 100 bases:

>100_bases
GGATCTACAAGATCACGGCGGCTGGCCGCAAACAGCTGGCTGTTGAAACCCGGCAGTACGCCAAACTTACGCTGGCGATT
GCCCGCGTAATGGGAACGGA

Downstream 100 bases:

>100_bases
AGTAGGCCATTGAGAAATCGCACGAGGTCCGGTAAATCGCCGGCACTGATTGAGAGCGGCGGTAACTTCAGCTGCTTCGC
GCGCCGGCACATCGCCACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 913; Mature: 912

Protein sequence:

>913_residues
MTGVLRRLRYLIGSARRSEALREEMELHLAEKASELEADGMTAEHARVEARRRFGNLGQKQEESREIWMTRFLSELVQDI
RYGCRTLSGNKAFSALAVLSLALGIGANTAIFSLMESILLRSLPVADPESLVVLNWHSRTPKDGDKESVHVMHGLQGMFW
PGKKGDMVTGIFPYRAFETLREENPVFSTLFGYVNGRNRTLAVRGQAMNASTEYVTGEYFRGLAVSPAAGRLIESEDDRP
GAAPVAVVSFATGQNRFGGPSNAIGQSILVDSVPFTVIGVAPPEFFGVDPAAAPEVYLPLHANLLVDGARAARIYGDENF
YWMEMMGRLRPGVSMAQAQAMLAPRFHQWVATTASTDGERAKLPALILNPGAAGLGSLRREYSKPLYVLLTMVALILAIT
CANIANLLLARSAARRREMAVRLSLGAGRLRIVRQMLTESVLLASLGGAFGVLFAVWGMRTLTFLLSSGQRNVTLHAELN
WSVLGVTAALSVVCGLLFGLAPAIQSTRPDVMPALKNGRGGGPRRRAQHVLVVGQIATSFLILVAAGLFVRTLNNLHSVQ
LGYARENILLFSLNARQAGHRDPEITAFYEDLRKRLESIPGVSSATLSHSSLIDAGFAGPAIRGEMKIGAVTVDDAGVLA
AGPRFLTTMQIPILAGREIDERDQRGSMPVAVISEELARTYFGDENPVGRRITLVDEKRELEIIGVSGNLRYGGLKEAEE
SSMTMFVAASQISPDRMTYALHTAGDPLRYVKSVHEIVREADSRIPVTNVATQAAEIDRTINREIMFAKLCTGFAVLALL
MACVGLYGTISYNVARQVGEIGIRMALGAQRGAVVWMVLSRVLLLAAVGLAISVPAALIASRLIKSFLFETRPNDPATLV
LAGVVLLSAVILAGYAPARRASRIDPLTALRHD

Sequences:

>Translated_913_residues
MTGVLRRLRYLIGSARRSEALREEMELHLAEKASELEADGMTAEHARVEARRRFGNLGQKQEESREIWMTRFLSELVQDI
RYGCRTLSGNKAFSALAVLSLALGIGANTAIFSLMESILLRSLPVADPESLVVLNWHSRTPKDGDKESVHVMHGLQGMFW
PGKKGDMVTGIFPYRAFETLREENPVFSTLFGYVNGRNRTLAVRGQAMNASTEYVTGEYFRGLAVSPAAGRLIESEDDRP
GAAPVAVVSFATGQNRFGGPSNAIGQSILVDSVPFTVIGVAPPEFFGVDPAAAPEVYLPLHANLLVDGARAARIYGDENF
YWMEMMGRLRPGVSMAQAQAMLAPRFHQWVATTASTDGERAKLPALILNPGAAGLGSLRREYSKPLYVLLTMVALILAIT
CANIANLLLARSAARRREMAVRLSLGAGRLRIVRQMLTESVLLASLGGAFGVLFAVWGMRTLTFLLSSGQRNVTLHAELN
WSVLGVTAALSVVCGLLFGLAPAIQSTRPDVMPALKNGRGGGPRRRAQHVLVVGQIATSFLILVAAGLFVRTLNNLHSVQ
LGYARENILLFSLNARQAGHRDPEITAFYEDLRKRLESIPGVSSATLSHSSLIDAGFAGPAIRGEMKIGAVTVDDAGVLA
AGPRFLTTMQIPILAGREIDERDQRGSMPVAVISEELARTYFGDENPVGRRITLVDEKRELEIIGVSGNLRYGGLKEAEE
SSMTMFVAASQISPDRMTYALHTAGDPLRYVKSVHEIVREADSRIPVTNVATQAAEIDRTINREIMFAKLCTGFAVLALL
MACVGLYGTISYNVARQVGEIGIRMALGAQRGAVVWMVLSRVLLLAAVGLAISVPAALIASRLIKSFLFETRPNDPATLV
LAGVVLLSAVILAGYAPARRASRIDPLTALRHD
>Mature_912_residues
TGVLRRLRYLIGSARRSEALREEMELHLAEKASELEADGMTAEHARVEARRRFGNLGQKQEESREIWMTRFLSELVQDIR
YGCRTLSGNKAFSALAVLSLALGIGANTAIFSLMESILLRSLPVADPESLVVLNWHSRTPKDGDKESVHVMHGLQGMFWP
GKKGDMVTGIFPYRAFETLREENPVFSTLFGYVNGRNRTLAVRGQAMNASTEYVTGEYFRGLAVSPAAGRLIESEDDRPG
AAPVAVVSFATGQNRFGGPSNAIGQSILVDSVPFTVIGVAPPEFFGVDPAAAPEVYLPLHANLLVDGARAARIYGDENFY
WMEMMGRLRPGVSMAQAQAMLAPRFHQWVATTASTDGERAKLPALILNPGAAGLGSLRREYSKPLYVLLTMVALILAITC
ANIANLLLARSAARRREMAVRLSLGAGRLRIVRQMLTESVLLASLGGAFGVLFAVWGMRTLTFLLSSGQRNVTLHAELNW
SVLGVTAALSVVCGLLFGLAPAIQSTRPDVMPALKNGRGGGPRRRAQHVLVVGQIATSFLILVAAGLFVRTLNNLHSVQL
GYARENILLFSLNARQAGHRDPEITAFYEDLRKRLESIPGVSSATLSHSSLIDAGFAGPAIRGEMKIGAVTVDDAGVLAA
GPRFLTTMQIPILAGREIDERDQRGSMPVAVISEELARTYFGDENPVGRRITLVDEKRELEIIGVSGNLRYGGLKEAEES
SMTMFVAASQISPDRMTYALHTAGDPLRYVKSVHEIVREADSRIPVTNVATQAAEIDRTINREIMFAKLCTGFAVLALLM
ACVGLYGTISYNVARQVGEIGIRMALGAQRGAVVWMVLSRVLLLAAVGLAISVPAALIASRLIKSFLFETRPNDPATLVL
AGVVLLSAVILAGYAPARRASRIDPLTALRHD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=314, Percent_Identity=26.1146496815287, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 98817; Mature: 98686

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVLRRLRYLIGSARRSEALREEMELHLAEKASELEADGMTAEHARVEARRRFGNLGQK
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
QEESREIWMTRFLSELVQDIRYGCRTLSGNKAFSALAVLSLALGIGANTAIFSLMESILL
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RSLPVADPESLVVLNWHSRTPKDGDKESVHVMHGLQGMFWPGKKGDMVTGIFPYRAFETL
HHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHH
REENPVFSTLFGYVNGRNRTLAVRGQAMNASTEYVTGEYFRGLAVSPAAGRLIESEDDRP
HHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHCCEECCCHHCCCCCCCCCCC
GAAPVAVVSFATGQNRFGGPSNAIGQSILVDSVPFTVIGVAPPEFFGVDPAAAPEVYLPL
CCCCEEEEEEECCCCCCCCCCHHHCCHHHCCCCCEEEEECCCCHHCCCCCCCCCCEEEEE
HANLLVDGARAARIYGDENFYWMEMMGRLRPGVSMAQAQAMLAPRFHQWVATTASTDGER
ECCEEEECCCEEEEECCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKLPALILNPGAAGLGSLRREYSKPLYVLLTMVALILAITCANIANLLLARSAARRREMA
CCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VRLSLGAGRLRIVRQMLTESVLLASLGGAFGVLFAVWGMRTLTFLLSSGQRNVTLHAELN
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
WSVLGVTAALSVVCGLLFGLAPAIQSTRPDVMPALKNGRGGGPRRRAQHVLVVGQIATSF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHCEEEEEHHHHHHH
LILVAAGLFVRTLNNLHSVQLGYARENILLFSLNARQAGHRDPEITAFYEDLRKRLESIP
HHHHHHHHHHHHHHHHHHEEECEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
GVSSATLSHSSLIDAGFAGPAIRGEMKIGAVTVDDAGVLAAGPRFLTTMQIPILAGREID
CCCHHHCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEEEEEEECCCCCC
ERDQRGSMPVAVISEELARTYFGDENPVGRRITLVDEKRELEIIGVSGNLRYGGLKEAEE
CHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCC
SSMTMFVAASQISPDRMTYALHTAGDPLRYVKSVHEIVREADSRIPVTNVATQAAEIDRT
CCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
INREIMFAKLCTGFAVLALLMACVGLYGTISYNVARQVGEIGIRMALGAQRGAVVWMVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
RVLLLAAVGLAISVPAALIASRLIKSFLFETRPNDPATLVLAGVVLLSAVILAGYAPARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
ASRIDPLTALRHD
HCCCCHHHHHCCC
>Mature Secondary Structure 
TGVLRRLRYLIGSARRSEALREEMELHLAEKASELEADGMTAEHARVEARRRFGNLGQK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
QEESREIWMTRFLSELVQDIRYGCRTLSGNKAFSALAVLSLALGIGANTAIFSLMESILL
HHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RSLPVADPESLVVLNWHSRTPKDGDKESVHVMHGLQGMFWPGKKGDMVTGIFPYRAFETL
HHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHH
REENPVFSTLFGYVNGRNRTLAVRGQAMNASTEYVTGEYFRGLAVSPAAGRLIESEDDRP
HHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHCCEECCCHHCCCCCCCCCCC
GAAPVAVVSFATGQNRFGGPSNAIGQSILVDSVPFTVIGVAPPEFFGVDPAAAPEVYLPL
CCCCEEEEEEECCCCCCCCCCHHHCCHHHCCCCCEEEEECCCCHHCCCCCCCCCCEEEEE
HANLLVDGARAARIYGDENFYWMEMMGRLRPGVSMAQAQAMLAPRFHQWVATTASTDGER
ECCEEEECCCEEEEECCCCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
AKLPALILNPGAAGLGSLRREYSKPLYVLLTMVALILAITCANIANLLLARSAARRREMA
CCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VRLSLGAGRLRIVRQMLTESVLLASLGGAFGVLFAVWGMRTLTFLLSSGQRNVTLHAELN
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
WSVLGVTAALSVVCGLLFGLAPAIQSTRPDVMPALKNGRGGGPRRRAQHVLVVGQIATSF
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHCEEEEEHHHHHHH
LILVAAGLFVRTLNNLHSVQLGYARENILLFSLNARQAGHRDPEITAFYEDLRKRLESIP
HHHHHHHHHHHHHHHHHHEEECEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCC
GVSSATLSHSSLIDAGFAGPAIRGEMKIGAVTVDDAGVLAAGPRFLTTMQIPILAGREID
CCCHHHCCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEECCCCEEEEEEEEEECCCCCC
ERDQRGSMPVAVISEELARTYFGDENPVGRRITLVDEKRELEIIGVSGNLRYGGLKEAEE
CHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCC
SSMTMFVAASQISPDRMTYALHTAGDPLRYVKSVHEIVREADSRIPVTNVATQAAEIDRT
CCEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
INREIMFAKLCTGFAVLALLMACVGLYGTISYNVARQVGEIGIRMALGAQRGAVVWMVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
RVLLLAAVGLAISVPAALIASRLIKSFLFETRPNDPATLVLAGVVLLSAVILAGYAPARR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHH
ASRIDPLTALRHD
HCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA