The gene/protein map for NC_008536 is currently unavailable.
Definition Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome.
Accession NC_008536
Length 9,965,640

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The map label for this gene is uxuB [H]

Identifier: 116622979

GI number: 116622979

Start: 4914881

End: 4915642

Strand: Reverse

Name: uxuB [H]

Synonym: Acid_3882

Alternate gene names: 116622979

Gene position: 4915642-4914881 (Counterclockwise)

Preceding gene: 116622980

Following gene: 116622977

Centisome position: 49.33

GC content: 59.97

Gene sequence:

>762_bases
ATGTTTTCATTGACCGGCCAGGTGGCGGTAGTTATCGGCGGCGGCGGAGTCCTCGCCGGGGCGATGGCCACGGGATTGGC
GAAAGCCGGCGCCGATATCGCGATTCTGGACGTGAGCAAAGACAATGCCGAAGGACGGGCCAAGTCGATCGAGACCTTAG
GGCGCGCGGCGATCGGCGTGGTTTGCGACGCCACCAGCAAGACGAGCCTTGAGGACGCGTTGGATTCGATCCTGGAACGC
TTCGGGCATGTCGATATTCTGGTCAATGCCGCCGGCGTAAATTCCGGCACCCCATTCTTCGAGATCTCGGAGACCGAGTG
GCAGCGCATCATGGATATCGATCTGAAGAGCGTCTTCCTGGCCTGCCAGGTTTTCGGTAAGCAGATGGTGGATGCCGCCC
ACGGCGGTTCGATCATTAATATCTCGTCGGCATCCTCGGGGCCGCCCCTGTCGAAGGTTTTCACCTACGCGGTGGCTAAA
GCCGGGGTTAATCAGATCACGCAGTACCTGGCGCGGGAGCTGGCCCCCCATAGCATCCGGGTCAACGCGATCCTTCCAGG
TTTCTTCCCGGCCGAGCAGAATCGGAAGCTGCTTACCGACGAGCGAGTTGCAAGCATTCTGGGGCATACCCCGATGCAAC
GTTTTGGGGAAAGCTGCGAACTGGTCGGCGCCACGGTGTACCTGGCATCCCAGCAGGCGTCGTCTTTCGTGACGGGGTCG
ATCCTAAAGGTTGACGGCGGATTTACGGCAATGACGATCTAA

Upstream 100 bases:

>100_bases
TCGCCGCACAGCAGCTCATAAAGGAGTTGTAGGATCGCGCATCATCGTTGAATTTTAAGACATACAGATCTGATACTATC
AGGGCATGTCGGAGAACGGA

Downstream 100 bases:

>100_bases
GCACCTTCTCGCAGAGCCGCAGAGCCGCAAAGTAACGCAAAGAAGAAAAATGGTAAGGGTTTTCTCTGCGTTAACTCTGC
GGCTCTGCGGCTCTGCGAGA

Product: short-chain dehydrogenase/reductase SDR

Products: @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate!; NADH. [C]

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MFSLTGQVAVVIGGGGVLAGAMATGLAKAGADIAILDVSKDNAEGRAKSIETLGRAAIGVVCDATSKTSLEDALDSILER
FGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFLACQVFGKQMVDAAHGGSIINISSASSGPPLSKVFTYAVAK
AGVNQITQYLARELAPHSIRVNAILPGFFPAEQNRKLLTDERVASILGHTPMQRFGESCELVGATVYLASQQASSFVTGS
ILKVDGGFTAMTI

Sequences:

>Translated_253_residues
MFSLTGQVAVVIGGGGVLAGAMATGLAKAGADIAILDVSKDNAEGRAKSIETLGRAAIGVVCDATSKTSLEDALDSILER
FGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFLACQVFGKQMVDAAHGGSIINISSASSGPPLSKVFTYAVAK
AGVNQITQYLARELAPHSIRVNAILPGFFPAEQNRKLLTDERVASILGHTPMQRFGESCELVGATVYLASQQASSFVTGS
ILKVDGGFTAMTI
>Mature_253_residues
MFSLTGQVAVVIGGGGVLAGAMATGLAKAGADIAILDVSKDNAEGRAKSIETLGRAAIGVVCDATSKTSLEDALDSILER
FGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFLACQVFGKQMVDAAHGGSIINISSASSGPPLSKVFTYAVAK
AGVNQITQYLARELAPHSIRVNAILPGFFPAEQNRKLLTDERVASILGHTPMQRFGESCELVGATVYLASQQASSFVTGS
ILKVDGGFTAMTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=29.8804780876494, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=29.718875502008, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=28.5123966942149, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=29.4573643410853, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=28.1124497991968, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4758504, Length=262, Percent_Identity=29.3893129770992, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=31.0880829015544, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=30.2631578947368, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI209862901, Length=210, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19923983, Length=210, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=29.296875, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI83715985, Length=262, Percent_Identity=27.4809160305344, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=38.4, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=36.144578313253, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.8709677419355, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=32.9218106995885, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=34.136546184739, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=31.3008130081301, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=31.5175097276265, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.6451612903226, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=29.5275590551181, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367175, Length=166, Percent_Identity=33.7349397590361, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=27.3076923076923, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788891, Length=243, Percent_Identity=25.1028806584362, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=34.0080971659919, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=29.3172690763052, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=27.3092369477912, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.5092936802974, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=180, Percent_Identity=30.5555555555556, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=179, Percent_Identity=30.7262569832402, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=27.9245283018868, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=27.7566539923954, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=33.4630350194552, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=32.4110671936759, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.1954887218045, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=29.6442687747036, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=29.6296296296296, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=26.4925373134328, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=28.1954887218045, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=25.9541984732824, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=26.865671641791, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=25.8555133079848, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=25.2830188679245, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=25.3787878787879, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=24.812030075188, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=24.9056603773585, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555612, Length=264, Percent_Identity=28.4090909090909, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=25.1336898395722, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=26.7175572519084, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=23.8636363636364, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17564282, Length=184, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322861, Length=263, Percent_Identity=23.9543726235741, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=31.1284046692607, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=31.5175097276265, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=29.1497975708502, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=31.2252964426877, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=28.3524904214559, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644337, Length=236, Percent_Identity=30.9322033898305, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17737361, Length=262, Percent_Identity=28.2442748091603, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640492, Length=224, Percent_Identity=26.3392857142857, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649181, Length=201, Percent_Identity=30.8457711442786, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18859837, Length=245, Percent_Identity=27.3469387755102, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665243, Length=177, Percent_Identity=29.3785310734463, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125 [C]

Molecular weight: Translated: 26380; Mature: 26380

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MFSLTGQVAVVIGGGGVLAGAMATGLAKAGADIAILDVSKDNAEGRAKSIETLGRAAIGV
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEE
VCDATSKTSLEDALDSILERFGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFL
EECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHH
ACQVFGKQMVDAAHGGSIINISSASSGPPLSKVFTYAVAKAGVNQITQYLARELAPHSIR
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VNAILPGFFPAEQNRKLLTDERVASILGHTPMQRFGESCELVGATVYLASQQASSFVTGS
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCHHEEEEEEEEECHHCCCHHCCE
ILKVDGGFTAMTI
EEEECCCEEEEEC
>Mature Secondary Structure
MFSLTGQVAVVIGGGGVLAGAMATGLAKAGADIAILDVSKDNAEGRAKSIETLGRAAIGV
CCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEE
VCDATSKTSLEDALDSILERFGHVDILVNAAGVNSGTPFFEISETEWQRIMDIDLKSVFL
EECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHH
ACQVFGKQMVDAAHGGSIINISSASSGPPLSKVFTYAVAKAGVNQITQYLARELAPHSIR
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
VNAILPGFFPAEQNRKLLTDERVASILGHTPMQRFGESCELVGATVYLASQQASSFVTGS
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCHHEEEEEEEEECHHCCCHHCCE
ILKVDGGFTAMTI
EEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 15.4 {2-deoxygluconate}} [C]

Substrates: @DEOX03.txt*2-Deoxy-D-Gluconate!; NAD(+) [C]

Specific reaction: @DEOX03.txt*2-Deoxy-D-Gluconate! + NAD(+) = @DEHY06.txt*3-Dehydro-2- Deoxy-D-Gluconate! + NADH. [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]