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The map label for this gene is ybdL [H]

Identifier: 116622717

GI number: 116622717

Start: 4574739

End: 4575920

Strand: Reverse

Name: ybdL [H]

Synonym: Acid_3616

Alternate gene names: 116622717

Gene position: 4575920-4574739 (Counterclockwise)

Preceding gene: 116622718

Following gene: 116622716

Centisome position: 45.92

GC content: 58.38

Gene sequence:

>1182_bases
GTGTCGACTACTGCCGCAGCATTCCGCAACCGCTTCCGCAGCCAGAGGATTTCACGCTTCACCGAATCCGTAATTCGCGA
GATGAGTCGCCTCGCGATTCGCCATGGAGCTACCAACCTGGCCCAGGGATTCCCCGATTTTCCCGCTCCCGAGGCCCTGA
AGCGTGCCGCGGCGGAGGCCATCGACTCCGATATCAATCAGTACGCGATCACTTGGGGAGCCAAGCCCTTCCGCGATGCG
ATCGCGGCTAAGTACCAGCGCACGTATGGCATGGAGTTCGACCCCGAGCGCGAGATCACCGTCTGCTGCGGCGCTACCGA
GGGCATGGTCGCCTCTCTCCTCGCCGTGGTAGACCCGGGCGACGAAATCGTCCTCTTCGAGCCCTTCTACGAGAATTACG
GCCCCGATTCGCAGCTCTGCGGCGCCGTCCCGCGCTACGTCAAACTCCAGGCGCCTGATTGGAATTTCGATCCCGACGAG
CTCCGCGCCGCCTTCGGTCCGCGCACCAAGGCGATCATTCTCAATTCGCCCAATAACCCAACGGGAAAGGTATTTACCCG
GCAGGAATTGGAGTTCATCGCCGGACTTTGCCAGGAATTCGACGTCCTCGCGATCACCGACGAAATCTACGAGCATATTC
TTTACGACGGCGCCGTCCATATCCCCATCATGTCGCTGCCGGGGATGCGGGACCGCTCAATTTTGGTGAACAGCATGAGC
AAGACCTACTCCGTAACCGGCTGGCGGGTCGGTTGGGTGCTGGCTTCACCAGATTTGACGGATTCCATCCGCAAGGTTCA
CGACTTTCTAACGGTAGGAGCGGCGGCGCCGCTCCAGCAAGCCGGCGTCCTCGCCCTATCCTTGCCGGAAGACTATTACG
AGCATCTCTCCACCGAGTACTCGGGCCGCCGCGACCATATCGTCGAGAGCCTGGAAGCGGTTGGTTTTAAATGTTTTGTG
CCGCACGGCGCATATTATGTCATGACCGACGTATCGGGTTTTGGCTTTTCTGACGATACTTCCTTCGTGCGGCATCTGAT
CACGAACCTCGGAGTTGCGGCAGTCCCGGGATCGAGTTTTTACGCACACCCTGCGACCGGCAGCCAGCAAGTACGCTTTT
GTTTTTGTAAGAAATATGAGACTCTGGAGTTAGCCAGAAGCAAATTTCTGAAGCTCCAGTAG

Upstream 100 bases:

>100_bases
TGCAGCCTCCGTAGCGATATCTTTTGCGGGTATTCTTAAGCTTTCAATCCGCAACGCTCACGGGCTTGCCGTTCGCCTGC
CTCTCAAGTACCCTCGTAGG

Downstream 100 bases:

>100_bases
GCGAGTGGCAGGGTTGGAAATTTCGTCAGGCGGAGAAGTCCTATGCTCCCAGAGTTCTTAGTAGCGGAAACAACCGTCCG
CGAAGCCGGAACCGGGCCTG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSTTAAAFRNRFRSQRISRFTESVIREMSRLAIRHGATNLAQGFPDFPAPEALKRAAAEAIDSDINQYAITWGAKPFRDA
IAAKYQRTYGMEFDPEREITVCCGATEGMVASLLAVVDPGDEIVLFEPFYENYGPDSQLCGAVPRYVKLQAPDWNFDPDE
LRAAFGPRTKAIILNSPNNPTGKVFTRQELEFIAGLCQEFDVLAITDEIYEHILYDGAVHIPIMSLPGMRDRSILVNSMS
KTYSVTGWRVGWVLASPDLTDSIRKVHDFLTVGAAAPLQQAGVLALSLPEDYYEHLSTEYSGRRDHIVESLEAVGFKCFV
PHGAYYVMTDVSGFGFSDDTSFVRHLITNLGVAAVPGSSFYAHPATGSQQVRFCFCKKYETLELARSKFLKLQ

Sequences:

>Translated_393_residues
MSTTAAAFRNRFRSQRISRFTESVIREMSRLAIRHGATNLAQGFPDFPAPEALKRAAAEAIDSDINQYAITWGAKPFRDA
IAAKYQRTYGMEFDPEREITVCCGATEGMVASLLAVVDPGDEIVLFEPFYENYGPDSQLCGAVPRYVKLQAPDWNFDPDE
LRAAFGPRTKAIILNSPNNPTGKVFTRQELEFIAGLCQEFDVLAITDEIYEHILYDGAVHIPIMSLPGMRDRSILVNSMS
KTYSVTGWRVGWVLASPDLTDSIRKVHDFLTVGAAAPLQQAGVLALSLPEDYYEHLSTEYSGRRDHIVESLEAVGFKCFV
PHGAYYVMTDVSGFGFSDDTSFVRHLITNLGVAAVPGSSFYAHPATGSQQVRFCFCKKYETLELARSKFLKLQ
>Mature_392_residues
STTAAAFRNRFRSQRISRFTESVIREMSRLAIRHGATNLAQGFPDFPAPEALKRAAAEAIDSDINQYAITWGAKPFRDAI
AAKYQRTYGMEFDPEREITVCCGATEGMVASLLAVVDPGDEIVLFEPFYENYGPDSQLCGAVPRYVKLQAPDWNFDPDEL
RAAFGPRTKAIILNSPNNPTGKVFTRQELEFIAGLCQEFDVLAITDEIYEHILYDGAVHIPIMSLPGMRDRSILVNSMSK
TYSVTGWRVGWVLASPDLTDSIRKVHDFLTVGAAAPLQQAGVLALSLPEDYYEHLSTEYSGRRDHIVESLEAVGFKCFVP
HGAYYVMTDVSGFGFSDDTSFVRHLITNLGVAAVPGSSFYAHPATGSQQVRFCFCKKYETLELARSKFLKLQ

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=418, Percent_Identity=36.8421052631579, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI169881279, Length=418, Percent_Identity=36.8421052631579, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI56713254, Length=416, Percent_Identity=36.7788461538462, Blast_Score=268, Evalue=5e-72,
Organism=Homo sapiens, GI56713256, Length=405, Percent_Identity=37.037037037037, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI169881281, Length=418, Percent_Identity=33.0143540669856, Blast_Score=231, Evalue=6e-61,
Organism=Homo sapiens, GI4507369, Length=337, Percent_Identity=24.3323442136499, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1786816, Length=377, Percent_Identity=35.0132625994695, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=27.7044854881267, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788627, Length=339, Percent_Identity=28.9085545722714, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787909, Length=307, Percent_Identity=26.0586319218241, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=31.0679611650485, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=31.0679611650485, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17567369, Length=413, Percent_Identity=28.5714285714286, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17567663, Length=331, Percent_Identity=28.0966767371601, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=386, Percent_Identity=32.1243523316062, Blast_Score=209, Evalue=7e-55,
Organism=Drosophila melanogaster, GI28573069, Length=402, Percent_Identity=35.3233830845771, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24646114, Length=402, Percent_Identity=35.3233830845771, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI28573067, Length=402, Percent_Identity=35.3233830845771, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI28573065, Length=402, Percent_Identity=35.3233830845771, Blast_Score=264, Evalue=7e-71,
Organism=Drosophila melanogaster, GI18859735, Length=333, Percent_Identity=28.5285285285285, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45551451, Length=397, Percent_Identity=23.9294710327456, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641770, Length=397, Percent_Identity=23.9294710327456, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641760, Length=397, Percent_Identity=23.9294710327456, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641768, Length=397, Percent_Identity=23.9294710327456, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641766, Length=397, Percent_Identity=23.9294710327456, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641764, Length=397, Percent_Identity=23.9294710327456, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 43706; Mature: 43575

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00105 AA_TRANSFER_CLASS_1 ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTAAAFRNRFRSQRISRFTESVIREMSRLAIRHGATNLAQGFPDFPAPEALKRAAAEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHH
IDSDINQYAITWGAKPFRDAIAAKYQRTYGMEFDPEREITVCCGATEGMVASLLAVVDPG
HHCCCHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
DEIVLFEPFYENYGPDSQLCGAVPRYVKLQAPDWNFDPDELRAAFGPRTKAIILNSPNNP
CCEEEECCHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCC
TGKVFTRQELEFIAGLCQEFDVLAITDEIYEHILYDGAVHIPIMSLPGMRDRSILVNSMS
CCCEEEHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHH
KTYSVTGWRVGWVLASPDLTDSIRKVHDFLTVGAAAPLQQAGVLALSLPEDYYEHLSTEY
CCEEECCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHCCEEEEECCHHHHHHHCCCC
SGRRDHIVESLEAVGFKCFVPHGAYYVMTDVSGFGFSDDTSFVRHLITNLGVAAVPGSSF
CCCHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEECCCCCE
YAHPATGSQQVRFCFCKKYETLELARSKFLKLQ
EECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTAAAFRNRFRSQRISRFTESVIREMSRLAIRHGATNLAQGFPDFPAPEALKRAAAEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHH
IDSDINQYAITWGAKPFRDAIAAKYQRTYGMEFDPEREITVCCGATEGMVASLLAVVDPG
HHCCCHHEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCC
DEIVLFEPFYENYGPDSQLCGAVPRYVKLQAPDWNFDPDELRAAFGPRTKAIILNSPNNP
CCEEEECCHHHCCCCCHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCC
TGKVFTRQELEFIAGLCQEFDVLAITDEIYEHILYDGAVHIPIMSLPGMRDRSILVNSMS
CCCEEEHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHH
KTYSVTGWRVGWVLASPDLTDSIRKVHDFLTVGAAAPLQQAGVLALSLPEDYYEHLSTEY
CCEEECCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHCCEEEEECCHHHHHHHCCCC
SGRRDHIVESLEAVGFKCFVPHGAYYVMTDVSGFGFSDDTSFVRHLITNLGVAAVPGSSF
CCCHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCEEECCCCCE
YAHPATGSQQVRFCFCKKYETLELARSKFLKLQ
EECCCCCCCCEEEHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]