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The map label for this gene is fixN [H]

Identifier: 116622609

GI number: 116622609

Start: 4438979

End: 4440376

Strand: Direct

Name: fixN [H]

Synonym: Acid_3507

Alternate gene names: 116622609

Gene position: 4438979-4440376 (Clockwise)

Preceding gene: 116622608

Following gene: 116622610

Centisome position: 44.54

GC content: 61.52

Gene sequence:

>1398_bases
ATGCCACAAGATAGTGTGCAATCCACCGCGACCTACCCGGCGGCTCCCGCGGCGGTCGCGCATGAGGACACCACCGCGAA
ATGGTTCCTCATCAGTTCCGTGATGTACTTCGTCATCGTCGGTATCATCGCCGTCACGATCGCGGCCAAGTTCGTCTGGC
CCTCGCTCCTGGGGACGGTCCAATACCTCACCTACGGCCGCCTACGCCCGCTGCACGTCAACGGCATGCTCTTCGGATGG
CTGCTCGCCGCCGACATGGGACTGGCCTATTTCATCGTGCCCCGCCTCTGCGGCGTCAAGCTGTGGAGCGAAAAACTCGG
TGTCGCCACCGCCGTGCTGTGGAATGTCATTATCCTCGGCGCCGTGGTCAGCCTGCTCGCCGGCTGGAACCAGGGCCTCG
AATACGCCGAGCTGCCCATGTTCCTCGATATCCTCGTCGTCATCGCGTGGATCATGTTCGGCGCCAATATCTTCGGCACC
ATCATGACCCGCAAGTACGAGCAGATGTACGTCTCCCTCTGGTACATCATGGGCACCATCCTGTGGACGGCCTTCGTCTA
CCTGACCGGCAACTTCGCCGTCCTGTTCGCGACCGGCGTCAACCAGGCCAACCTCAACTGGATGTATGTCCACAACGCCG
TCGGCCTGATCTTCACCCCGATCGGCCTCGCGATCGCGTATTACATGATTCCGAAGGCCTCCGACACGCCGCTCCACAGT
CACAAGCTGTCGATGATCGGCTTCTGGTCGCTGGCCTTCGTCTACGTCTGGACCGGCGCCCATCACATGCTCCACGGTCC
CATCTCGCAATGGCTGCAGACCATCGCGATCGCCTTCAGCGTGATGCTGCTGATCCCGGTCTGGGCCGTGGTCCACAACT
TCTTCGCCACCATGCAGGGCCAGTGGCACCAGCTCCGCGAAAACGTGCCGCTGAAATTCCTCATGTCCGGCGTCGTCTTC
TATCTGCTCACCTGCTTCCAGGGCCCGATGCACAGCCTGCGCACCGTCAACGCCATCGTCTCCAAGACCGATTGGATTCC
CGGCCACGCCCACATGGCCGTGCTCGGCTGCTTCTCCTTCTTCGCCATCGCCGGAACTTACTACACCGTGCCGCGCGTCT
TCAAGACCTCGCTCTTCTCGGACCTGCTCGCCAACTGGAGCTTCTGGTTCCTCATGATCGGCGGCCTCGGCTTCTTCGTG
ACGCTCTGGATCGGCGGCTTCTGGCAGGGCTGGCAGTGGAACAACCCGTCCATCCCCTTCATCGATACCGTGGTCGCGCT
CAAGCCCATCTGGCTGGTCCGCTTCTTTTCCGGCACCCTGATGCTCACCGGCATCGTGCTCTTCGCGTACAACATCCTGG
CCACCATCGTGGGCGTAAGGAGGACATCCGAATGCTAA

Upstream 100 bases:

>100_bases
ATGCCGTCATGGATCGATTACGGCCTGTCCCAAAACGACGTCGGCAACCTGGTCAATTTCATCCGCAGTATTAATGCCAA
GACCCCAGAGAGGAATCTCC

Downstream 100 bases:

>100_bases
GGAAAGCCGATACCAGCGCCGGCGCCGCCGTCGTCTTCGCCCTGGCGTTCTTCTTCGTCGGCGGAGTCCTCACCACCGTC
GTTCCGCCCCTGGTCGATAA

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome c oxidase polypeptide I homolog [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MPQDSVQSTATYPAAPAAVAHEDTTAKWFLISSVMYFVIVGIIAVTIAAKFVWPSLLGTVQYLTYGRLRPLHVNGMLFGW
LLAADMGLAYFIVPRLCGVKLWSEKLGVATAVLWNVIILGAVVSLLAGWNQGLEYAELPMFLDILVVIAWIMFGANIFGT
IMTRKYEQMYVSLWYIMGTILWTAFVYLTGNFAVLFATGVNQANLNWMYVHNAVGLIFTPIGLAIAYYMIPKASDTPLHS
HKLSMIGFWSLAFVYVWTGAHHMLHGPISQWLQTIAIAFSVMLLIPVWAVVHNFFATMQGQWHQLRENVPLKFLMSGVVF
YLLTCFQGPMHSLRTVNAIVSKTDWIPGHAHMAVLGCFSFFAIAGTYYTVPRVFKTSLFSDLLANWSFWFLMIGGLGFFV
TLWIGGFWQGWQWNNPSIPFIDTVVALKPIWLVRFFSGTLMLTGIVLFAYNILATIVGVRRTSEC

Sequences:

>Translated_465_residues
MPQDSVQSTATYPAAPAAVAHEDTTAKWFLISSVMYFVIVGIIAVTIAAKFVWPSLLGTVQYLTYGRLRPLHVNGMLFGW
LLAADMGLAYFIVPRLCGVKLWSEKLGVATAVLWNVIILGAVVSLLAGWNQGLEYAELPMFLDILVVIAWIMFGANIFGT
IMTRKYEQMYVSLWYIMGTILWTAFVYLTGNFAVLFATGVNQANLNWMYVHNAVGLIFTPIGLAIAYYMIPKASDTPLHS
HKLSMIGFWSLAFVYVWTGAHHMLHGPISQWLQTIAIAFSVMLLIPVWAVVHNFFATMQGQWHQLRENVPLKFLMSGVVF
YLLTCFQGPMHSLRTVNAIVSKTDWIPGHAHMAVLGCFSFFAIAGTYYTVPRVFKTSLFSDLLANWSFWFLMIGGLGFFV
TLWIGGFWQGWQWNNPSIPFIDTVVALKPIWLVRFFSGTLMLTGIVLFAYNILATIVGVRRTSEC
>Mature_464_residues
PQDSVQSTATYPAAPAAVAHEDTTAKWFLISSVMYFVIVGIIAVTIAAKFVWPSLLGTVQYLTYGRLRPLHVNGMLFGWL
LAADMGLAYFIVPRLCGVKLWSEKLGVATAVLWNVIILGAVVSLLAGWNQGLEYAELPMFLDILVVIAWIMFGANIFGTI
MTRKYEQMYVSLWYIMGTILWTAFVYLTGNFAVLFATGVNQANLNWMYVHNAVGLIFTPIGLAIAYYMIPKASDTPLHSH
KLSMIGFWSLAFVYVWTGAHHMLHGPISQWLQTIAIAFSVMLLIPVWAVVHNFFATMQGQWHQLRENVPLKFLMSGVVFY
LLTCFQGPMHSLRTVNAIVSKTDWIPGHAHMAVLGCFSFFAIAGTYYTVPRVFKTSLFSDLLANWSFWFLMIGGLGFFVT
LWIGGFWQGWQWNNPSIPFIDTVVALKPIWLVRFFSGTLMLTGIVLFAYNILATIVGVRRTSEC

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 52189; Mature: 52058

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50855 COX1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQDSVQSTATYPAAPAAVAHEDTTAKWFLISSVMYFVIVGIIAVTIAAKFVWPSLLGTV
CCCCHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYLTYGRLRPLHVNGMLFGWLLAADMGLAYFIVPRLCGVKLWSEKLGVATAVLWNVIILG
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVSLLAGWNQGLEYAELPMFLDILVVIAWIMFGANIFGTIMTRKYEQMYVSLWYIMGTI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWTAFVYLTGNFAVLFATGVNQANLNWMYVHNAVGLIFTPIGLAIAYYMIPKASDTPLHS
HHHHHHHHHCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
HKLSMIGFWSLAFVYVWTGAHHMLHGPISQWLQTIAIAFSVMLLIPVWAVVHNFFATMQG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QWHQLRENVPLKFLMSGVVFYLLTCFQGPMHSLRTVNAIVSKTDWIPGHAHMAVLGCFSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FAIAGTYYTVPRVFKTSLFSDLLANWSFWFLMIGGLGFFVTLWIGGFWQGWQWNNPSIPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
IDTVVALKPIWLVRFFSGTLMLTGIVLFAYNILATIVGVRRTSEC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PQDSVQSTATYPAAPAAVAHEDTTAKWFLISSVMYFVIVGIIAVTIAAKFVWPSLLGTV
CCCHHCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYLTYGRLRPLHVNGMLFGWLLAADMGLAYFIVPRLCGVKLWSEKLGVATAVLWNVIILG
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVSLLAGWNQGLEYAELPMFLDILVVIAWIMFGANIFGTIMTRKYEQMYVSLWYIMGTI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWTAFVYLTGNFAVLFATGVNQANLNWMYVHNAVGLIFTPIGLAIAYYMIPKASDTPLHS
HHHHHHHHHCCEEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
HKLSMIGFWSLAFVYVWTGAHHMLHGPISQWLQTIAIAFSVMLLIPVWAVVHNFFATMQG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
QWHQLRENVPLKFLMSGVVFYLLTCFQGPMHSLRTVNAIVSKTDWIPGHAHMAVLGCFSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FAIAGTYYTVPRVFKTSLFSDLLANWSFWFLMIGGLGFFVTLWIGGFWQGWQWNNPSIPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
IDTVVALKPIWLVRFFSGTLMLTGIVLFAYNILATIVGVRRTSEC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7753030 [H]