Click here to switch to the map view.

The map label for this gene is 116622507

Identifier: 116622507

GI number: 116622507

Start: 4308924

End: 4310570

Strand: Reverse

Name: 116622507

Synonym: Acid_3405

Alternate gene names: NA

Gene position: 4310570-4308924 (Counterclockwise)

Preceding gene: 116622508

Following gene: 116622505

Centisome position: 43.25

GC content: 64.85

Gene sequence:

>1647_bases
ATGCAGGTCAAGCGCTCGCCCGAGGTCCACGACGTCGTCATCGTCGGCAGCGGCGCTTCCGGCGGCATGGCCGCGTGGAA
CCTCACCCGCAAGGGATTGCGCGTCCTGATGCTGGACGCCGGAACGAAGTTCCCGCGCTCGCAATTCTGGAGTCACGTCA
AGCCCTGGCAGGTGCCGGAGAAGGTCGCCGCCGGACAGAAGCCGCCGCAATTCTACGTGGACCTGAAGACCGCACCCTTC
CAGACTCCGCCGGGACAGCCCTTCGACCTGGTGCGCGTCTGGGGGCGCGGCGGCAAGACCAATGTCTGGGGCCGTGTTTC
CCTGCGCTATGCCGATCTCGATTTCGCCGGCGCCGAGCGCGACGGCTGGGAGATCCCATGGCCCATCCGCTATAAGGATC
TCGCGCCCTACTATGACAACGTCGATCGGCTGATCGGCGTGTGCGGCGGCGATGACGATCAGGATTCACTGCCCGGCAGC
CGCTATCATCTTCCGCCGCCGCCTCCGCGATGCGGGGAACGTCTGCTGCAGCGGGCCGCCGGCAAGATCGGCGTCAGCAT
CGTGGCCGGACGCCGCGCCGTGCTCACCCGCCCGCACAACGGCCGCGCCGCCTGCCACTATTGCGGCGCCTGCGGCAAAG
GCTGCGACGTCGGCGCCTTCTTCAATTCCTCGGACTACCTGATCGAACCGGCGCTTGCCTCGCAGCGTCTGCAGGTGATC
GATAACGCGGTGGTGGCGCGCATCCTCACCGATGACGAGGGCCGCGCCAACGGTGTGCAGTACTTCGACCGCTTCACGAA
GGAAGAACACACCGTGAAGGCGCGCGTGGTCGTGGTCGCCGCGTCGTGCATCGATTCCACCCGCATTCTGCTCAACTCGA
AATCGAGCCGCCATCCGAATGGGATCGGCAATTCCTCCGACGTGGTGGGCCGCTACTTGAGCGAGCAGGTCCGCCTGCAC
ATGTTCGGCTTCGTACCGGAATTACTCGGCGCGCCCGTGCAGAATGACGACGGCATCGGCGGCGAGCACGTCTACATGCC
GCGCTTCAACCATCGCGACGGCCGCAAGCGCGATTACCTGCGCGGCTTCGGCATGCAGTTCTGGGGCTGCGGCGCCGGCG
ATAACGCCGGTTGGGCGAAGGAGATTCCGGGCTTCGGCGCGGAGTTCAAGACTGCCGTGCGCAAGCGCTATCCGGCGCTC
GTGGCGCTTCATCCGTACGGCGAGGTACTGCCGTATGCCGACAACCGGATCACGGTCGGCAGCGCCGGAGTGGACAGTTA
TGGCGTTCCGATCGCGCGCATCGAATTCAAGTACCGCGAGAACGAGCGCAAGATGATGACCGAGATGTATCAGACCGCGG
CTGCGATCCTCAAGGAGGCAAAGGCCGAGATTCTGCCCTATGACCCGTCATTCATGGGCATTCCCGGACAGGCGATTCAC
GAACACGGCACCTGCCGCATGGGGACGGACCCCAAGCGCAGCGCCCTCAACGGCTTCTGCCAGATGCACGACGTGAAGAA
CGTTTTTGTAGTGGATGGCGCCGCCTTCACCACGGCGTCGGAGAAGAATCCCACTCTGACTATCCTGGCGCTCGCGTGGC
GCGCCACGGATTATCTCGCCAACGAACTCAAGGCCAAGCGCCTATAG

Upstream 100 bases:

>100_bases
ACTACACCTCCAAAGAAGGCCTCGCCGGCGAACTCGGCTGGCACGGCAACACGTACCTCACCGAATTCAAGGGCTGCACC
CATCCGGAGCACCAGCGCTG

Downstream 100 bases:

>100_bases
CCCATAGGGCAAGACGCCTGGCCCACATCCCGTCAGCCCGCGGCTTTCATGGCGGTCCCGAATCTTCTCGGGTCAACGCC
CGAACTTGCGGTCGCCGGTT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MQVKRSPEVHDVVIVGSGASGGMAAWNLTRKGLRVLMLDAGTKFPRSQFWSHVKPWQVPEKVAAGQKPPQFYVDLKTAPF
QTPPGQPFDLVRVWGRGGKTNVWGRVSLRYADLDFAGAERDGWEIPWPIRYKDLAPYYDNVDRLIGVCGGDDDQDSLPGS
RYHLPPPPPRCGERLLQRAAGKIGVSIVAGRRAVLTRPHNGRAACHYCGACGKGCDVGAFFNSSDYLIEPALASQRLQVI
DNAVVARILTDDEGRANGVQYFDRFTKEEHTVKARVVVVAASCIDSTRILLNSKSSRHPNGIGNSSDVVGRYLSEQVRLH
MFGFVPELLGAPVQNDDGIGGEHVYMPRFNHRDGRKRDYLRGFGMQFWGCGAGDNAGWAKEIPGFGAEFKTAVRKRYPAL
VALHPYGEVLPYADNRITVGSAGVDSYGVPIARIEFKYRENERKMMTEMYQTAAAILKEAKAEILPYDPSFMGIPGQAIH
EHGTCRMGTDPKRSALNGFCQMHDVKNVFVVDGAAFTTASEKNPTLTILALAWRATDYLANELKAKRL

Sequences:

>Translated_548_residues
MQVKRSPEVHDVVIVGSGASGGMAAWNLTRKGLRVLMLDAGTKFPRSQFWSHVKPWQVPEKVAAGQKPPQFYVDLKTAPF
QTPPGQPFDLVRVWGRGGKTNVWGRVSLRYADLDFAGAERDGWEIPWPIRYKDLAPYYDNVDRLIGVCGGDDDQDSLPGS
RYHLPPPPPRCGERLLQRAAGKIGVSIVAGRRAVLTRPHNGRAACHYCGACGKGCDVGAFFNSSDYLIEPALASQRLQVI
DNAVVARILTDDEGRANGVQYFDRFTKEEHTVKARVVVVAASCIDSTRILLNSKSSRHPNGIGNSSDVVGRYLSEQVRLH
MFGFVPELLGAPVQNDDGIGGEHVYMPRFNHRDGRKRDYLRGFGMQFWGCGAGDNAGWAKEIPGFGAEFKTAVRKRYPAL
VALHPYGEVLPYADNRITVGSAGVDSYGVPIARIEFKYRENERKMMTEMYQTAAAILKEAKAEILPYDPSFMGIPGQAIH
EHGTCRMGTDPKRSALNGFCQMHDVKNVFVVDGAAFTTASEKNPTLTILALAWRATDYLANELKAKRL
>Mature_548_residues
MQVKRSPEVHDVVIVGSGASGGMAAWNLTRKGLRVLMLDAGTKFPRSQFWSHVKPWQVPEKVAAGQKPPQFYVDLKTAPF
QTPPGQPFDLVRVWGRGGKTNVWGRVSLRYADLDFAGAERDGWEIPWPIRYKDLAPYYDNVDRLIGVCGGDDDQDSLPGS
RYHLPPPPPRCGERLLQRAAGKIGVSIVAGRRAVLTRPHNGRAACHYCGACGKGCDVGAFFNSSDYLIEPALASQRLQVI
DNAVVARILTDDEGRANGVQYFDRFTKEEHTVKARVVVVAASCIDSTRILLNSKSSRHPNGIGNSSDVVGRYLSEQVRLH
MFGFVPELLGAPVQNDDGIGGEHVYMPRFNHRDGRKRDYLRGFGMQFWGCGAGDNAGWAKEIPGFGAEFKTAVRKRYPAL
VALHPYGEVLPYADNRITVGSAGVDSYGVPIARIEFKYRENERKMMTEMYQTAAAILKEAKAEILPYDPSFMGIPGQAIH
EHGTCRMGTDPKRSALNGFCQMHDVKNVFVVDGAAFTTASEKNPTLTILALAWRATDYLANELKAKRL

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 60483; Mature: 60483

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKRSPEVHDVVIVGSGASGGMAAWNLTRKGLRVLMLDAGTKFPRSQFWSHVKPWQVPE
CCCCCCCCCEEEEEEECCCCCCEEEEHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCH
KVAAGQKPPQFYVDLKTAPFQTPPGQPFDLVRVWGRGGKTNVWGRVSLRYADLDFAGAER
HHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHEECCCCCCCEEEEEEEEEECCCCCCCCC
DGWEIPWPIRYKDLAPYYDNVDRLIGVCGGDDDQDSLPGSRYHLPPPPPRCGERLLQRAA
CCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GKIGVSIVAGRRAVLTRPHNGRAACHYCGACGKGCDVGAFFNSSDYLIEPALASQRLQVI
CCCCEEEEECCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCEECCHHHHHHHHHH
DNAVVARILTDDEGRANGVQYFDRFTKEEHTVKARVVVVAASCIDSTRILLNSKSSRHPN
HHHHEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCCC
GIGNSSDVVGRYLSEQVRLHMFGFVPELLGAPVQNDDGIGGEHVYMPRFNHRDGRKRDYL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHH
RGFGMQFWGCGAGDNAGWAKEIPGFGAEFKTAVRKRYPALVALHPYGEVLPYADNRITVG
HHCCCCEEECCCCCCCCCHHHCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEC
SAGVDSYGVPIARIEFKYRENERKMMTEMYQTAAAILKEAKAEILPYDPSFMGIPGQAIH
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
EHGTCRMGTDPKRSALNGFCQMHDVKNVFVVDGAAFTTASEKNPTLTILALAWRATDYLA
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCEEEEEEEHHHHHHHH
NELKAKRL
HHHHHCCC
>Mature Secondary Structure
MQVKRSPEVHDVVIVGSGASGGMAAWNLTRKGLRVLMLDAGTKFPRSQFWSHVKPWQVPE
CCCCCCCCCEEEEEEECCCCCCEEEEHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCH
KVAAGQKPPQFYVDLKTAPFQTPPGQPFDLVRVWGRGGKTNVWGRVSLRYADLDFAGAER
HHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHEECCCCCCCEEEEEEEEEECCCCCCCCC
DGWEIPWPIRYKDLAPYYDNVDRLIGVCGGDDDQDSLPGSRYHLPPPPPRCGERLLQRAA
CCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GKIGVSIVAGRRAVLTRPHNGRAACHYCGACGKGCDVGAFFNSSDYLIEPALASQRLQVI
CCCCEEEEECCEEEEECCCCCCCCEEECCCCCCCCCEEEEECCCCCEECCHHHHHHHHHH
DNAVVARILTDDEGRANGVQYFDRFTKEEHTVKARVVVVAASCIDSTRILLNSKSSRHPN
HHHHEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCEEEEEECCCCCCCC
GIGNSSDVVGRYLSEQVRLHMFGFVPELLGAPVQNDDGIGGEHVYMPRFNHRDGRKRDYL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHH
RGFGMQFWGCGAGDNAGWAKEIPGFGAEFKTAVRKRYPALVALHPYGEVLPYADNRITVG
HHCCCCEEECCCCCCCCCHHHCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEC
SAGVDSYGVPIARIEFKYRENERKMMTEMYQTAAAILKEAKAEILPYDPSFMGIPGQAIH
CCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
EHGTCRMGTDPKRSALNGFCQMHDVKNVFVVDGAAFTTASEKNPTLTILALAWRATDYLA
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCEEEEEEEHHHHHHHH
NELKAKRL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]