| Definition | Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome. |
|---|---|
| Accession | NC_008536 |
| Length | 9,965,640 |
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The map label for this gene is yusZ [H]
Identifier: 116622499
GI number: 116622499
Start: 4300542
End: 4301408
Strand: Reverse
Name: yusZ [H]
Synonym: Acid_3397
Alternate gene names: 116622499
Gene position: 4301408-4300542 (Counterclockwise)
Preceding gene: 116622501
Following gene: 116622498
Centisome position: 43.16
GC content: 61.71
Gene sequence:
>867_bases ATGAGTCAAACAACAGCGAAGACACTCTCACGAATTCCGGTCTCCTCCCCGGTATGGTTCATTACCGGCATTGGGCGAGG CCTTGGGCGGAGCATCGCCGGGGAAGTGATGCGCCGCGGCGGCAGGGTGGCGGGTACCGTCCGAAAACTCGAGGACGCGG ACGAACTGAAGAGGCAATACCCGGATCAGCTTTGGACCGGAGAACTCGAGTTGTCCAATTTCGCTAATATTGCGAATACC TTCGGAGCTGCCGTCCGGCACTTCGGGCGAATCCACGCGGTTGTCAGTAACGCCGGATACAGCCTGCTGGGCGCGGCGGA AGAACTGGAGCTCGATGCGATCCGGCACATTATCGACACGAATCTCATCGGCTCCATCGAACTGGCGCGGGCAGCCGTGG CGCACATGCGTCCGCTCGGAGGGGGCCGTCTTATCCAGGTATCCAGCGGCGCCGGCCAGGCGGGCTTTCCCGGCCTTTCG CTCTATTGCGCCACCAAATGGGGCATCGAAGGTTTTTTCGACTCGCTCGCGCAGGAGGTGGCTGACTTTGGGATCCAGAC GACGCTTGTGGAACCGGGCACCATACGGACGGGCTTTGGGAGCTCAGGTGTTCTGAGTCCTGAACTGGAGGCCTATCGCG ATGGTCCGGCCGGAATGCTGCGCAAGATGGCAATGCAGGGTTACCCGGCGCCGGGAGATCCCGCTAAGATGGCGAAGGCA ATCGTGGAGACGTTCGAAGCCGACGCGGCGCCGACGCGGCTCGCTCTTGGCCAGGATGCCTATGGATATATCAAGGCGGC ACTCGCCGGCAGGCTGGCCCAGGTGGAGGCTCATAAGAATCTCGCGACCGACTGCGACGACGTATAA
Upstream 100 bases:
>100_bases CCGGGTACCGCGAGCGCTTCCCAAACACTTTGGAGAATTTTGATAATTTCTCGGGGAGTTTCTTTAACAGAATCGCACTT CTGCCGGCTACAGTCGAGGC
Downstream 100 bases:
>100_bases CATTCGCCGGCTTATGGCAGTTAGCATAGTGGAGATGCGCGCATCGAATTCGCTCTGGAGAGAGGCACGTTCGATTCTGG TCCGGCATTGCGAGGAGGAC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: ORFA [H]
Number of amino acids: Translated: 288; Mature: 287
Protein sequence:
>288_residues MSQTTAKTLSRIPVSSPVWFITGIGRGLGRSIAGEVMRRGGRVAGTVRKLEDADELKRQYPDQLWTGELELSNFANIANT FGAAVRHFGRIHAVVSNAGYSLLGAAEELELDAIRHIIDTNLIGSIELARAAVAHMRPLGGGRLIQVSSGAGQAGFPGLS LYCATKWGIEGFFDSLAQEVADFGIQTTLVEPGTIRTGFGSSGVLSPELEAYRDGPAGMLRKMAMQGYPAPGDPAKMAKA IVETFEADAAPTRLALGQDAYGYIKAALAGRLAQVEAHKNLATDCDDV
Sequences:
>Translated_288_residues MSQTTAKTLSRIPVSSPVWFITGIGRGLGRSIAGEVMRRGGRVAGTVRKLEDADELKRQYPDQLWTGELELSNFANIANT FGAAVRHFGRIHAVVSNAGYSLLGAAEELELDAIRHIIDTNLIGSIELARAAVAHMRPLGGGRLIQVSSGAGQAGFPGLS LYCATKWGIEGFFDSLAQEVADFGIQTTLVEPGTIRTGFGSSGVLSPELEAYRDGPAGMLRKMAMQGYPAPGDPAKMAKA IVETFEADAAPTRLALGQDAYGYIKAALAGRLAQVEAHKNLATDCDDV >Mature_287_residues SQTTAKTLSRIPVSSPVWFITGIGRGLGRSIAGEVMRRGGRVAGTVRKLEDADELKRQYPDQLWTGELELSNFANIANTF GAAVRHFGRIHAVVSNAGYSLLGAAEELELDAIRHIIDTNLIGSIELARAAVAHMRPLGGGRLIQVSSGAGQAGFPGLSL YCATKWGIEGFFDSLAQEVADFGIQTTLVEPGTIRTGFGSSGVLSPELEAYRDGPAGMLRKMAMQGYPAPGDPAKMAKAI VETFEADAAPTRLALGQDAYGYIKAALAGRLAQVEAHKNLATDCDDV
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=30.5, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI19743808, Length=269, Percent_Identity=28.2527881040892, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=33.6898395721925, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI7657478, Length=253, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI50726952, Length=266, Percent_Identity=27.4436090225564, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI22507405, Length=186, Percent_Identity=31.7204301075269, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=31.4917127071823, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI44680136, Length=204, Percent_Identity=28.4313725490196, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI44680133, Length=204, Percent_Identity=28.4313725490196, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI17738292, Length=204, Percent_Identity=28.4313725490196, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI4503817, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=26.4550264550265, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=26.3959390862944, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI157739938, Length=205, Percent_Identity=25.3658536585366, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI119392083, Length=192, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI19923817, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=249, Percent_Identity=26.1044176706827, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI40548397, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI214010158, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI214010156, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI22758144, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI142976729, Length=208, Percent_Identity=26.4423076923077, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI25282469, Length=234, Percent_Identity=26.4957264957265, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787335, Length=182, Percent_Identity=32.4175824175824, Blast_Score=78, Evalue=8e-16, Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=28.2485875706215, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1786701, Length=182, Percent_Identity=28.021978021978, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=31.0526315789474, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1786812, Length=196, Percent_Identity=26.0204081632653, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI2367175, Length=195, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71997402, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17570069, Length=203, Percent_Identity=29.064039408867, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI71994604, Length=232, Percent_Identity=26.7241379310345, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17507613, Length=254, Percent_Identity=25.1968503937008, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI32563809, Length=254, Percent_Identity=25.1968503937008, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI115534660, Length=182, Percent_Identity=26.9230769230769, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71994600, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=30.2083333333333, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=191, Percent_Identity=27.7486910994764, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17564282, Length=201, Percent_Identity=29.8507462686567, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203117, Length=203, Percent_Identity=29.5566502463054, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.8195488721804, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI193203115, Length=207, Percent_Identity=29.4685990338164, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=26.7015706806283, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322226, Length=234, Percent_Identity=24.3589743589744, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=27.6041666666667, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21356301, Length=232, Percent_Identity=25.4310344827586, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=25.3886010362694, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI23397609, Length=234, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI21355631, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=8e-12, Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=24.2268041237113, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=26.2626262626263, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI28571387, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=6e-11, Organism=Drosophila melanogaster, GI24644339, Length=228, Percent_Identity=25, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 30476; Mature: 30345
Theoretical pI: Translated: 6.37; Mature: 6.37
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSQTTAKTLSRIPVSSPVWFITGIGRGLGRSIAGEVMRRGGRVAGTVRKLEDADELKRQY CCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC PDQLWTGELELSNFANIANTFGAAVRHFGRIHAVVSNAGYSLLGAAEELELDAIRHIIDT CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHH NLIGSIELARAAVAHMRPLGGGRLIQVSSGAGQAGFPGLSLYCATKWGIEGFFDSLAQEV CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHCHHHHHHHHHHHH ADFGIQTTLVEPGTIRTGFGSSGVLSPELEAYRDGPAGMLRKMAMQGYPAPGDPAKMAKA HHCCCEEEEECCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHH IVETFEADAAPTRLALGQDAYGYIKAALAGRLAQVEAHKNLATDCDDV HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure SQTTAKTLSRIPVSSPVWFITGIGRGLGRSIAGEVMRRGGRVAGTVRKLEDADELKRQY CCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC PDQLWTGELELSNFANIANTFGAAVRHFGRIHAVVSNAGYSLLGAAEELELDAIRHIIDT CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHH NLIGSIELARAAVAHMRPLGGGRLIQVSSGAGQAGFPGLSLYCATKWGIEGFFDSLAQEV CCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHCHHHHHHHHHHHH ADFGIQTTLVEPGTIRTGFGSSGVLSPELEAYRDGPAGMLRKMAMQGYPAPGDPAKMAKA HHCCCEEEEECCCCEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHH IVETFEADAAPTRLALGQDAYGYIKAALAGRLAQVEAHKNLATDCDDV HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9353931; 9384377; 8396117 [H]