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The map label for this gene is pntAB [H]

Identifier: 116622476

GI number: 116622476

Start: 4275936

End: 4276232

Strand: Reverse

Name: pntAB [H]

Synonym: Acid_3374

Alternate gene names: 116622476

Gene position: 4276232-4275936 (Counterclockwise)

Preceding gene: 116622477

Following gene: 116622475

Centisome position: 42.91

GC content: 56.23

Gene sequence:

>297_bases
ATGCCTTCGAATCTGGAAATCGGATTGTACGTCTTCATGCTGGCGACCTTCGTCGGGCTGGAAGTGATCCGCAAGGTCTC
GCCGCTACTGCACACACCCCTGATGTCGCTCACCAACGCGATCTCGGCGATCTCGGTAGTGGGCGCGATCCTGATCATCA
GCAACGAAGACGCGACCACACTGAGCAAGGTGCTGGGCTTTATCGCGATCACGGCGGCTGTGACCAACATCGTGAGCGGA
TTTCTGATCACGGACCGCATGCTGAAGATGTTTAAGAAGCGCGAGGAGAAGCGATAA

Upstream 100 bases:

>100_bases
TCGTGCGCGAGACGCTGGTTACGTATGGCGGAGAAGTGGTGCATGCGCGGGTGCGGGAAGCAATGGGGCTGCCGGTAGCG
GGGTAAGAAGGAGGGGGCTG

Downstream 100 bases:

>100_bases
TGAACTCGCTCGTCAGCTACATCTACATCATCTCGGGCGCGCTCTTCATTCTCTCTCTGAAATGGATGAACTCGCCGGTG
AGCGCGCGGCGCGGTGTCTT

Product: nicotinamide nucleotide transhydrogenase subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MPSNLEIGLYVFMLATFVGLEVIRKVSPLLHTPLMSLTNAISAISVVGAILIISNEDATTLSKVLGFIAITAAVTNIVSG
FLITDRMLKMFKKREEKR

Sequences:

>Translated_98_residues
MPSNLEIGLYVFMLATFVGLEVIRKVSPLLHTPLMSLTNAISAISVVGAILIISNEDATTLSKVLGFIAITAAVTNIVSG
FLITDRMLKMFKKREEKR
>Mature_97_residues
PSNLEIGLYVFMLATFVGLEVIRKVSPLLHTPLMSLTNAISAISVVGAILIISNEDATTLSKVLGFIAITAAVTNIVSGF
LITDRMLKMFKKREEKR

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=43.3734939759036, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=43.3734939759036, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787887, Length=83, Percent_Identity=54.2168674698795, Blast_Score=78, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550456, Length=90, Percent_Identity=40, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10695; Mature: 10564

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNLEIGLYVFMLATFVGLEVIRKVSPLLHTPLMSLTNAISAISVVGAILIISNEDATT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LSKVLGFIAITAAVTNIVSGFLITDRMLKMFKKREEKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSNLEIGLYVFMLATFVGLEVIRKVSPLLHTPLMSLTNAISAISVVGAILIISNEDATT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LSKVLGFIAITAAVTNIVSGFLITDRMLKMFKKREEKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]