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The map label for this gene is macB [H]

Identifier: 116621977

GI number: 116621977

Start: 3623252

End: 3624451

Strand: Direct

Name: macB [H]

Synonym: Acid_2862

Alternate gene names: 116621977

Gene position: 3623252-3624451 (Clockwise)

Preceding gene: 116621976

Following gene: 116621978

Centisome position: 36.36

GC content: 62.08

Gene sequence:

>1200_bases
ATGTTCCTCGGCGAAGCGGTCCGGTTCAGCGCGCAGGCGTTGCGCGCCAGTCCTGTCCGTTCGCTGCTCACCGGGCTCGG
CATGGCCATCGGCACTGCCTCCGTCATCCTTGTCGTCACCATCTCCCTCACCAGCCGCGACTACATTCTCGAGCAGGTCC
AGGGCATCGGTTCCAACATAATATTCGCCTACTACGCCAACGCCGGTGGCTCCACCGTCGCCGACGCCGACTACATTAAG
ATGACCGACGTCCACGCCCTACGCCAGGAGCTCACCGCCGATATCGTGGCCGCGACCGGCGTCATGTCCAATTTCGACCG
CATCCTGATCGGCGGCAAAGAGCAGGACGTCAAAGTCATCGGCACCGACCAGGACTACCAGCCGGTCCGCAACATCGTCA
TCAGTTCCGGCCGCTTCCTGGATGAAAGCGACATCACGCTCCGCGGCAAGACTGCCCTCCTCACCGACCAACTCGCCACC
CGCATGTTCGGCGGACGCGCCGCCGCCCTCAGCCAGGTCATCAAGCTCTACGGCCTGGAATTCACGGTCATCGGCACCTT
CCATGAAAAAGTCGAGACCTTTGGACAATCGGAAGTCGAGCGGGATACGATACTTATCCCCATAACTGTCTTGCGTTACT
TTACCCCCGTGGAGCGCATCGATCCCCTCTACGTCCAGGTCCGTTCGCCCCAGGAAGTCGAGCGCGTAGCACTCCGCGTT
CAGCAGATCCTCGAGGCCCGCCACCGCCCCGGCGCCCGCTACCGTGTGGACACCCTCACCGCCATTCTGAACGCCGCCAA
GAATATTTCCCTGATCCTCTCTCTGGTCCTGGTCCTGGTGTCGGCCATCACCCTCGTCATCTCCGGAATCGGCATTATGA
ACATCATGCTCGTCACCGTGACCGAGCGCACCCGCGAGATCGGCGTCCGCCTCGCCGTCGGTGCCTCCCCCCGCGAGATT
CTCCTTCAGTTCCTCGCCGAAGCCATCATGGTCAGCCTCACCGGCGGTGTCGCCGGCATCCTGGCCGGAATCGCAATCCC
GCTCAGCGTCCAATTGTTCGCCGATATCAAAATCCCGATTTCGCCGGTTGCGATTGTCGTGGCCTTCGGGGTTTCGTGCC
TCGTCGGCCTGATTTTCGGCATCCTCCCCGCCAACCGTGCCGCCCATTTACACCCCACCGAAGCGCTCCGTTATGAGTAG

Upstream 100 bases:

>100_bases
CCTGAAGAAATACCTGAGCCTCGCTTTGACCCCTGACGACCCGTCGCGGTCGGAGGCCGAGAAGCTGCTCAAGCAGGTGC
AGGGCAGCTAAGCCCAGCCC

Downstream 100 bases:

>100_bases
TGACGTCAACATCAAATTTATTTTTCCCAGCCTAACCTGTTAGCAACATTACTCTTCGTCGAAAATGTCCTATAGGAATA
CTGCTTGTTTCACTTGCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNIIFAYYANAGGSTVADADYIK
MTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVIGTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLAT
RMFGGRAAALSQVIKLYGLEFTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRV
QQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTVTERTREIGVRLAVGASPREI
LLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPISPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE

Sequences:

>Translated_399_residues
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNIIFAYYANAGGSTVADADYIK
MTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVIGTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLAT
RMFGGRAAALSQVIKLYGLEFTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRV
QQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTVTERTREIGVRLAVGASPREI
LLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPISPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE
>Mature_399_residues
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNIIFAYYANAGGSTVADADYIK
MTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVIGTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLAT
RMFGGRAAALSQVIKLYGLEFTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRV
QQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTVTERTREIGVRLAVGASPREI
LLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPISPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=402, Percent_Identity=32.089552238806, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43065; Mature: 43065

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHCCCCCE
IFAYYANAGGSTVADADYIKMTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVI
EEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
GTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLATRMFGGRAAALSQVIKLYGLE
ECCCCHHHHHHHHHCCCCEECCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCE
FTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRV
EEEEEHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHCCCEEEEECCHHHHHHHHHHH
QQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
TERTREIGVRLAVGASPREILLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPI
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCEEEEEEEEECCCC
SPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHHHHCCCCCE
IFAYYANAGGSTVADADYIKMTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVI
EEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
GTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLATRMFGGRAAALSQVIKLYGLE
ECCCCHHHHHHHHHCCCCEECCCCCEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCE
FTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRV
EEEEEHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHCCCEEEEECCHHHHHHHHHHH
QQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
TERTREIGVRLAVGASPREILLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPI
HHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCEEEEEEEEECCCC
SPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA