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The map label for this gene is lptD [H]

Identifier: 116621846

GI number: 116621846

Start: 3458590

End: 3461031

Strand: Direct

Name: lptD [H]

Synonym: Acid_2728

Alternate gene names: 116621846

Gene position: 3458590-3461031 (Clockwise)

Preceding gene: 116621844

Following gene: 116621847

Centisome position: 34.71

GC content: 57.58

Gene sequence:

>2442_bases
TTGAGGTCCTGCCCAAAAAGCTCTCTCATAGTAGTTAGCATAAAGCGATCTCCATGTCACGCAAAATCTTCGAGTATTAC
GTGTCATTTCCCTCTTACGCTGTTGCTTGCGCTGATTTTAGCCGTTAGCGCGGCGGCTCAGGTGAATCCCGGATCCACGC
AAGAGACGCCTCCCGCGGTGCCGCCCAAGTCGCTGTCCGTGGGCTCGTGGAACATCAGCGCTCCGGTCCAGCAAAAGGAT
GGGGACGTATTCACACTGCACGGAAATCCGGCGGAGGTGGAAAGCGCCACCATGATTTTCCGCGCCGACGATATCGTGTT
CAACCAGGAGACCGGCGACCTGAAAGCCACGGGCCACGTCTTCTTCCATGACTTCCTGAAAAATCAGAAAATCTGGGCAT
CGCACGTCACCTACAACACCGATGAAGAGAGCGGCAAGTTCTACGACGTGATCGGCGAGACGATGCCACACATCGTCGCC
AAGCCCGGGATGCTGACCACCAATAATCCATTTCACTTCGAAGGCGAATGGGCGGAGCGCATCGGGATGAAATACATTCT
GCATCATGGCTTCGTGACGAATTGCAAGATGCCGCAGCCCTGGTGGAAAATGCGCGCCAAGACCTTCGACATCATTCCCG
GCGAGCGCGCCATCTCTCACAACAGCACGTTCGTTCTGCGCAAGCTGCCGATCTTCTACGCGCCGTTTTTCTACCACTCG
CTGGAGAAGGAGCCGCGCAAGAGCGGTCTGCTGATGCCGCTGGTGGGGAACAGCTCACGGCGCGGCTTCATGGTGCATGC
CGGATATTTCTGGGCGATTAACCGCAGCTACGACGTCAGCTACCTGGGGCAGTATTACACTACACGCGGGCTGGTGCATC
ACGTTGATTTCCGCGGCAAACCGCGCGCCGGCACCGACTACGACGCCATCCTCTACGGCGTCCAGGATCGCGGATTGCCG
GACAGCGGGAATCCGCCGCAGAAATTCAGCGGCCTGAGCCTCCTGGTGGTCGGCAAGAGCGACTTGGGCAAGGGCTGGAC
GGCGCGCGGCAGCCTTAATTACATCACCTCGTTTCGCTTCCGTCAGGAATGGAGTGAATCCTATGCCGATATCACCGGCT
CGGAAATTCACTCCGTGGGCTTCGTGAATAAGAACTGGTCGAACAACACGCTGAATGTGATCTTCGCGCGATTGCAGGAC
TTTCAGACCAGCGAGATCGCGGTGCCGGATAGTCCGGGCTCCAGTTCGACTCACTATGTGAGTAACGCGGTCACAATCCG
CAAGTTACCCGAAGTGGAAGTAAGCGGCCGGGACCGGGAACTGCTGCCCAATCTCCCGTTGTATTACTCGTTCGAAACAT
CGGCGGGTTTGCTGTACCGCCAGTATCCCGTATTCAACAACAATGTGCTGGTGGATAACTATCAGACCAGCCAGTTCATG
AACCGTTCCAGCATCTCGCCGCACGTGTTCGGCGCCTTCCATTTTGCAGGCGTGCAACTGGTTCCCGGTTTCGGAATTGA
GGAAACGTACTACGGCGAAGCGCAGACTCCCTACCAGGGGAATTACCAGATCACCGGCACCAACCTGGTGCGCAGTACCC
GTGATTTCTCCCTGGACCTGATCCTGCCTTCGCTTTCCCGTATTTACAACAAGAAAACGATCTTCGGCGACAAACTTAAG
CACGTGATCGAAGCGCGCGCGACTTACCGCTATGTTACCGGGGTGGGCGAAGACTACGTGCGCTTCATCCGCTTCGACGA
GAACGACCTGGTTACCAACACCAACGAAGTCCTGCTATCGGTCGCCAACCGGATCTACGCCAAGCGGGGCAATTCGGTGG
AAGAAATCTTCACCTGGGAAGTCTTTCAGAAGCGCTATTTCGACCCCACCTTCGGCGGCGCGCTAATTCAGGGACAGCGC
AATGTCATCGAGAGCACCGCGGACCTCACCGCGTATGCTTTCCTGCTGGGGCCGCGCAGCACCTCCCCGATTGTCAGCGT
GCTGCGGACGAGCCCGATTCCCAACTTGAACCTGCGCTGGCGCGCCGACTACGACCCTCGCACCGGAAGCCTGGTGGACA
GCAGTCTCTCGGTGGATTACCGCCTGCGCAATTACTTCCTCGCGGTGGGCCACAGCACGGTCCACACCGACCCGGCGATC
ACCGCGCCCGCCAACCAGTTGAGCCTTCGCGGCGGCTTCGGCGACCCCAATCACAAGGGCATCAACGTGGGCGGCGAGGC
GATCTACGATTTGCGCGCGGGCACTATTCAATACAGTACGGCGCTGGTGCAGTACAACACCAACTGCTGCGGTTTCAGTG
TGCAATTTCACCGTGTGAACCTGGGCACGCACACCAACGACAATCAATACCGATTCGCCTTCGCGATCGCGAATATTGCA
ACCACGCTGGGAAACCTGAAAAAACAGGACCGGCTTTTCTAA

Upstream 100 bases:

>100_bases
CGAGTCCCACAGTAACGACAGGTCATTTCACATTGTTTCCGTCAGGCCACAGGTTGCCGGCCGCTTTATATTGCCTCACG
AAGTGTGCTAGCTTCTTCGA

Downstream 100 bases:

>100_bases
CGGATTCCCGTCCCTTTTTCGGCTGTTTTCCGCATGTACAGATATAACCTCTTGCAAAGTTCGGGGCGGGTGCTTCACCC
GAGTCACCGCCCCGTGCCCC

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 813; Mature: 813

Protein sequence:

>813_residues
MRSCPKSSLIVVSIKRSPCHAKSSSITCHFPLTLLLALILAVSAAAQVNPGSTQETPPAVPPKSLSVGSWNISAPVQQKD
GDVFTLHGNPAEVESATMIFRADDIVFNQETGDLKATGHVFFHDFLKNQKIWASHVTYNTDEESGKFYDVIGETMPHIVA
KPGMLTTNNPFHFEGEWAERIGMKYILHHGFVTNCKMPQPWWKMRAKTFDIIPGERAISHNSTFVLRKLPIFYAPFFYHS
LEKEPRKSGLLMPLVGNSSRRGFMVHAGYFWAINRSYDVSYLGQYYTTRGLVHHVDFRGKPRAGTDYDAILYGVQDRGLP
DSGNPPQKFSGLSLLVVGKSDLGKGWTARGSLNYITSFRFRQEWSESYADITGSEIHSVGFVNKNWSNNTLNVIFARLQD
FQTSEIAVPDSPGSSSTHYVSNAVTIRKLPEVEVSGRDRELLPNLPLYYSFETSAGLLYRQYPVFNNNVLVDNYQTSQFM
NRSSISPHVFGAFHFAGVQLVPGFGIEETYYGEAQTPYQGNYQITGTNLVRSTRDFSLDLILPSLSRIYNKKTIFGDKLK
HVIEARATYRYVTGVGEDYVRFIRFDENDLVTNTNEVLLSVANRIYAKRGNSVEEIFTWEVFQKRYFDPTFGGALIQGQR
NVIESTADLTAYAFLLGPRSTSPIVSVLRTSPIPNLNLRWRADYDPRTGSLVDSSLSVDYRLRNYFLAVGHSTVHTDPAI
TAPANQLSLRGGFGDPNHKGINVGGEAIYDLRAGTIQYSTALVQYNTNCCGFSVQFHRVNLGTHTNDNQYRFAFAIANIA
TTLGNLKKQDRLF

Sequences:

>Translated_813_residues
MRSCPKSSLIVVSIKRSPCHAKSSSITCHFPLTLLLALILAVSAAAQVNPGSTQETPPAVPPKSLSVGSWNISAPVQQKD
GDVFTLHGNPAEVESATMIFRADDIVFNQETGDLKATGHVFFHDFLKNQKIWASHVTYNTDEESGKFYDVIGETMPHIVA
KPGMLTTNNPFHFEGEWAERIGMKYILHHGFVTNCKMPQPWWKMRAKTFDIIPGERAISHNSTFVLRKLPIFYAPFFYHS
LEKEPRKSGLLMPLVGNSSRRGFMVHAGYFWAINRSYDVSYLGQYYTTRGLVHHVDFRGKPRAGTDYDAILYGVQDRGLP
DSGNPPQKFSGLSLLVVGKSDLGKGWTARGSLNYITSFRFRQEWSESYADITGSEIHSVGFVNKNWSNNTLNVIFARLQD
FQTSEIAVPDSPGSSSTHYVSNAVTIRKLPEVEVSGRDRELLPNLPLYYSFETSAGLLYRQYPVFNNNVLVDNYQTSQFM
NRSSISPHVFGAFHFAGVQLVPGFGIEETYYGEAQTPYQGNYQITGTNLVRSTRDFSLDLILPSLSRIYNKKTIFGDKLK
HVIEARATYRYVTGVGEDYVRFIRFDENDLVTNTNEVLLSVANRIYAKRGNSVEEIFTWEVFQKRYFDPTFGGALIQGQR
NVIESTADLTAYAFLLGPRSTSPIVSVLRTSPIPNLNLRWRADYDPRTGSLVDSSLSVDYRLRNYFLAVGHSTVHTDPAI
TAPANQLSLRGGFGDPNHKGINVGGEAIYDLRAGTIQYSTALVQYNTNCCGFSVQFHRVNLGTHTNDNQYRFAFAIANIA
TTLGNLKKQDRLF
>Mature_813_residues
MRSCPKSSLIVVSIKRSPCHAKSSSITCHFPLTLLLALILAVSAAAQVNPGSTQETPPAVPPKSLSVGSWNISAPVQQKD
GDVFTLHGNPAEVESATMIFRADDIVFNQETGDLKATGHVFFHDFLKNQKIWASHVTYNTDEESGKFYDVIGETMPHIVA
KPGMLTTNNPFHFEGEWAERIGMKYILHHGFVTNCKMPQPWWKMRAKTFDIIPGERAISHNSTFVLRKLPIFYAPFFYHS
LEKEPRKSGLLMPLVGNSSRRGFMVHAGYFWAINRSYDVSYLGQYYTTRGLVHHVDFRGKPRAGTDYDAILYGVQDRGLP
DSGNPPQKFSGLSLLVVGKSDLGKGWTARGSLNYITSFRFRQEWSESYADITGSEIHSVGFVNKNWSNNTLNVIFARLQD
FQTSEIAVPDSPGSSSTHYVSNAVTIRKLPEVEVSGRDRELLPNLPLYYSFETSAGLLYRQYPVFNNNVLVDNYQTSQFM
NRSSISPHVFGAFHFAGVQLVPGFGIEETYYGEAQTPYQGNYQITGTNLVRSTRDFSLDLILPSLSRIYNKKTIFGDKLK
HVIEARATYRYVTGVGEDYVRFIRFDENDLVTNTNEVLLSVANRIYAKRGNSVEEIFTWEVFQKRYFDPTFGGALIQGQR
NVIESTADLTAYAFLLGPRSTSPIVSVLRTSPIPNLNLRWRADYDPRTGSLVDSSLSVDYRLRNYFLAVGHSTVHTDPAI
TAPANQLSLRGGFGDPNHKGINVGGEAIYDLRAGTIQYSTALVQYNTNCCGFSVQFHRVNLGTHTNDNQYRFAFAIANIA
TTLGNLKKQDRLF

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR005653
- InterPro:   IPR007543 [H]

Pfam domain/function: PF03968 OstA; PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 91134; Mature: 91134

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSCPKSSLIVVSIKRSPCHAKSSSITCHFPLTLLLALILAVSAAAQVNPGSTQETPPAV
CCCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PPKSLSVGSWNISAPVQQKDGDVFTLHGNPAEVESATMIFRADDIVFNQETGDLKATGHV
CCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCEEEECCCCCEEECCHH
FFHDFLKNQKIWASHVTYNTDEESGKFYDVIGETMPHIVAKPGMLTTNNPFHFEGEWAER
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCEEECCHHHHH
IGMKYILHHGFVTNCKMPQPWWKMRAKTFDIIPGERAISHNSTFVLRKLPIFYAPFFYHS
CCHHHHHHCCEEECCCCCCHHHHHCCCEEEECCCCCEECCCCEEEEEECCHHHHHHHHHH
LEKEPRKSGLLMPLVGNSSRRGFMVHAGYFWAINRSYDVSYLGQYYTTRGLVHHVDFRGK
HHCCHHHCCEEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCC
PRAGTDYDAILYGVQDRGLPDSGNPPQKFSGLSLLVVGKSDLGKGWTARGSLNYITSFRF
CCCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEEEECCCCCCCCEECCCCCHHHHHHHH
RQEWSESYADITGSEIHSVGFVNKNWSNNTLNVIFARLQDFQTSEIAVPDSPGSSSTHYV
HHHHHHHHHCCCCCHHEEEECEECCCCCCHHHHHEEHHHCCCCCEEECCCCCCCCCCEEE
SNAVTIRKLPEVEVSGRDRELLPNLPLYYSFETSAGLLYRQYPVFNNNVLVDNYQTSQFM
ECEEEEEECCCCEECCCCHHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEECCCHHHHH
NRSSISPHVFGAFHFAGVQLVPGFGIEETYYGEAQTPYQGNYQITGTNLVRSTRDFSLDL
CCCCCCCCEEEEEEECCEEEECCCCCCCEECCCCCCCCCCCEEEECHHHHHCCCCCEEEE
ILPSLSRIYNKKTIFGDKLKHVIEARATYRYVTGVGEDYVRFIRFDENDLVTNTNEVLLS
EHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCHHHHHHH
VANRIYAKRGNSVEEIFTWEVFQKRYFDPTFGGALIQGQRNVIESTADLTAYAFLLGPRS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHEEEEEEECCCC
TSPIVSVLRTSPIPNLNLRWRADYDPRTGSLVDSSLSVDYRLRNYFLAVGHSTVHTDPAI
CCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECCCCEEEEEEEEEEEEECCCEECCCCCC
TAPANQLSLRGGFGDPNHKGINVGGEAIYDLRAGTIQYSTALVQYNTNCCGFSVQFHRVN
CCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCEEEEEEEEEEEE
LGTHTNDNQYRFAFAIANIATTLGNLKKQDRLF
ECCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSCPKSSLIVVSIKRSPCHAKSSSITCHFPLTLLLALILAVSAAAQVNPGSTQETPPAV
CCCCCCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PPKSLSVGSWNISAPVQQKDGDVFTLHGNPAEVESATMIFRADDIVFNQETGDLKATGHV
CCCCCCCCCEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCEEEECCCCCEEECCHH
FFHDFLKNQKIWASHVTYNTDEESGKFYDVIGETMPHIVAKPGMLTTNNPFHFEGEWAER
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCEEECCHHHHH
IGMKYILHHGFVTNCKMPQPWWKMRAKTFDIIPGERAISHNSTFVLRKLPIFYAPFFYHS
CCHHHHHHCCEEECCCCCCHHHHHCCCEEEECCCCCEECCCCEEEEEECCHHHHHHHHHH
LEKEPRKSGLLMPLVGNSSRRGFMVHAGYFWAINRSYDVSYLGQYYTTRGLVHHVDFRGK
HHCCHHHCCEEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCC
PRAGTDYDAILYGVQDRGLPDSGNPPQKFSGLSLLVVGKSDLGKGWTARGSLNYITSFRF
CCCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEEEECCCCCCCCEECCCCCHHHHHHHH
RQEWSESYADITGSEIHSVGFVNKNWSNNTLNVIFARLQDFQTSEIAVPDSPGSSSTHYV
HHHHHHHHHCCCCCHHEEEECEECCCCCCHHHHHEEHHHCCCCCEEECCCCCCCCCCEEE
SNAVTIRKLPEVEVSGRDRELLPNLPLYYSFETSAGLLYRQYPVFNNNVLVDNYQTSQFM
ECEEEEEECCCCEECCCCHHHCCCCCEEEEECCCCCEEEEECCCCCCCEEEECCCHHHHH
NRSSISPHVFGAFHFAGVQLVPGFGIEETYYGEAQTPYQGNYQITGTNLVRSTRDFSLDL
CCCCCCCCEEEEEEECCEEEECCCCCCCEECCCCCCCCCCCEEEECHHHHHCCCCCEEEE
ILPSLSRIYNKKTIFGDKLKHVIEARATYRYVTGVGEDYVRFIRFDENDLVTNTNEVLLS
EHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCCCCCCCHHHHHHH
VANRIYAKRGNSVEEIFTWEVFQKRYFDPTFGGALIQGQRNVIESTADLTAYAFLLGPRS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHEEEEEEECCCC
TSPIVSVLRTSPIPNLNLRWRADYDPRTGSLVDSSLSVDYRLRNYFLAVGHSTVHTDPAI
CCHHHHHHHCCCCCCCEEEEEECCCCCCCCEECCCCEEEEEEEEEEEEECCCEECCCCCC
TAPANQLSLRGGFGDPNHKGINVGGEAIYDLRAGTIQYSTALVQYNTNCCGFSVQFHRVN
CCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEEECCCEEEEEEEEEEEE
LGTHTNDNQYRFAFAIANIATTLGNLKKQDRLF
ECCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA