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The map label for this gene is lytS [H]

Identifier: 116621428

GI number: 116621428

Start: 2953176

End: 2954201

Strand: Reverse

Name: lytS [H]

Synonym: Acid_2310

Alternate gene names: 116621428

Gene position: 2954201-2953176 (Counterclockwise)

Preceding gene: 116621429

Following gene: 116621427

Centisome position: 29.64

GC content: 61.5

Gene sequence:

>1026_bases
ATGGTGACGTTGAGACGGCTCCGCACGATCGTGCTTCTGAATATCGCCGCAGGCGTGGCTGGATGCCTGCTGAGCATCTC
GGTATATCGTGCGAATACCGCGCAAATTGTTGCGAACTTCGAGCGCTCGCTAATCACGGCGTTCTTTGTCGTCACACCGG
TCGTCCTCCTGCTGGCGCGCTTCGGGATGCGCATGTATCGCGTGGGCGTTCCGTGGAACTGGATGCTGATCGTGACGGGA
ATTCTCGGGTGTACCATCGCGGGAACCCTGGCCTGCAGCGCGGTTTCGATTGCGCTCGGCCTGGTTCCGCAGGGCCATCT
CTGGATCATCTTTTGGGCACGGATTCAGTTTGCCGCGGTTCTGGCGCTGAGCATGGGGATCGGGGCGCTCAGCTACGGAG
CGGTGCGAAACCAACTGGAGGCCACCATGCTGGAACAGGAGCGCGCGCGGAAGCTGGCGGTGGAGGCGCGGCTTGCCTCG
CTCGAATCGCATGTCCGGCCGCATTTTCTGTTTAACACCCTGAACACCATCAGCTCGCTGATTCCGGAAGATCCGAAGCG
GGCCGAAACGCTGGTAGGAAAGCTCGCTGCGCTGTTGCGGCTCTCGCTCGATTCGAATCAAGCGCGGCTGGGATCGCTCG
AACGCGAACTGAAAATCATCGGCGACTATCTGGAAATTGAGCGGGCACGCTATGGCGAGCGCCTTCGCTTCCGCATCGAC
GTGCCACCAGAGCTTCGGCCGGTCCAGGTGCCGGCGCTGTCGCTGCAGACACTCGTAGAGAATAGCGTGAAGCACGCTGT
AGGATCGCGATTCGAGGGCGCGGAAGTCCGCGTTGTGGCATTTGAGCGCGACGGTTCGGTATTCGTGGAGGTATCGGACG
ATGGGCCGGGATTCACCGAACAGGCGATCCTCCCGGGGCACGGACTCGATAACTTACAACAGCGGCTGGTGACGATGTTT
GGGCCCGGCGCAAGGCTGGAGATTCGAGGCGGCCCGACCGTCTCGTTCTGCGTTCCACGCGGGTAA

Upstream 100 bases:

>100_bases
TCCGCCGGCGTTCTCGGAAGCGGCTTTCGAATTCGACGGCAAGACCGACAAGACGATCGCGTTCTCCATTCAGTATTGAG
CCTGCGCCACCTGTGGCAAC

Downstream 100 bases:

>100_bases
CCTCCATGTTCCGAGCCTATCTGGTCGATGACGAACTGCCCGCGGTAAAGCGGCTGGCGCGCCTGCTTCAGGCGACCGGG
CGGGTGGAAATCGTGGGCGC

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MVTLRRLRTIVLLNIAAGVAGCLLSISVYRANTAQIVANFERSLITAFFVVTPVVLLLARFGMRMYRVGVPWNWMLIVTG
ILGCTIAGTLACSAVSIALGLVPQGHLWIIFWARIQFAAVLALSMGIGALSYGAVRNQLEATMLEQERARKLAVEARLAS
LESHVRPHFLFNTLNTISSLIPEDPKRAETLVGKLAALLRLSLDSNQARLGSLERELKIIGDYLEIERARYGERLRFRID
VPPELRPVQVPALSLQTLVENSVKHAVGSRFEGAEVRVVAFERDGSVFVEVSDDGPGFTEQAILPGHGLDNLQQRLVTMF
GPGARLEIRGGPTVSFCVPRG

Sequences:

>Translated_341_residues
MVTLRRLRTIVLLNIAAGVAGCLLSISVYRANTAQIVANFERSLITAFFVVTPVVLLLARFGMRMYRVGVPWNWMLIVTG
ILGCTIAGTLACSAVSIALGLVPQGHLWIIFWARIQFAAVLALSMGIGALSYGAVRNQLEATMLEQERARKLAVEARLAS
LESHVRPHFLFNTLNTISSLIPEDPKRAETLVGKLAALLRLSLDSNQARLGSLERELKIIGDYLEIERARYGERLRFRID
VPPELRPVQVPALSLQTLVENSVKHAVGSRFEGAEVRVVAFERDGSVFVEVSDDGPGFTEQAILPGHGLDNLQQRLVTMF
GPGARLEIRGGPTVSFCVPRG
>Mature_341_residues
MVTLRRLRTIVLLNIAAGVAGCLLSISVYRANTAQIVANFERSLITAFFVVTPVVLLLARFGMRMYRVGVPWNWMLIVTG
ILGCTIAGTLACSAVSIALGLVPQGHLWIIFWARIQFAAVLALSMGIGALSYGAVRNQLEATMLEQERARKLAVEARLAS
LESHVRPHFLFNTLNTISSLIPEDPKRAETLVGKLAALLRLSLDSNQARLGSLERELKIIGDYLEIERARYGERLRFRID
VPPELRPVQVPALSLQTLVENSVKHAVGSRFEGAEVRVVAFERDGSVFVEVSDDGPGFTEQAILPGHGLDNLQQRLVTMF
GPGARLEIRGGPTVSFCVPRG

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3275

COG function: function code T; Putative regulator of cell autolysis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=217, Percent_Identity=32.258064516129, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788446, Length=188, Percent_Identity=30.3191489361702, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37364; Mature: 37364

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLRRLRTIVLLNIAAGVAGCLLSISVYRANTAQIVANFERSLITAFFVVTPVVLLLAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGMRMYRVGVPWNWMLIVTGILGCTIAGTLACSAVSIALGLVPQGHLWIIFWARIQFAAV
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
LALSMGIGALSYGAVRNQLEATMLEQERARKLAVEARLASLESHVRPHFLFNTLNTISSL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IPEDPKRAETLVGKLAALLRLSLDSNQARLGSLERELKIIGDYLEIERARYGERLRFRID
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
VPPELRPVQVPALSLQTLVENSVKHAVGSRFEGAEVRVVAFERDGSVFVEVSDDGPGFTE
CCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCC
QAILPGHGLDNLQQRLVTMFGPGARLEIRGGPTVSFCVPRG
CCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCC
>Mature Secondary Structure
MVTLRRLRTIVLLNIAAGVAGCLLSISVYRANTAQIVANFERSLITAFFVVTPVVLLLAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGMRMYRVGVPWNWMLIVTGILGCTIAGTLACSAVSIALGLVPQGHLWIIFWARIQFAAV
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHH
LALSMGIGALSYGAVRNQLEATMLEQERARKLAVEARLASLESHVRPHFLFNTLNTISSL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
IPEDPKRAETLVGKLAALLRLSLDSNQARLGSLERELKIIGDYLEIERARYGERLRFRID
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
VPPELRPVQVPALSLQTLVENSVKHAVGSRFEGAEVRVVAFERDGSVFVEVSDDGPGFTE
CCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCC
QAILPGHGLDNLQQRLVTMFGPGARLEIRGGPTVSFCVPRG
CCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]