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The map label for this gene is lytT [H]

Identifier: 116621427

GI number: 116621427

Start: 2952427

End: 2953170

Strand: Reverse

Name: lytT [H]

Synonym: Acid_2309

Alternate gene names: 116621427

Gene position: 2953170-2952427 (Counterclockwise)

Preceding gene: 116621428

Following gene: 116621426

Centisome position: 29.63

GC content: 60.22

Gene sequence:

>744_bases
ATGTTCCGAGCCTATCTGGTCGATGACGAACTGCCCGCGGTAAAGCGGCTGGCGCGCCTGCTTCAGGCGACCGGGCGGGT
GGAAATCGTGGGCGCCGAAATGAATCCTGTGGCGGCGATCGAGGCGATCCGGGTGGCATCACCCGACATACTCTTCTTAG
ACATTCAGATGCCCGGGCTCACCGGATTCGATTTGCTGGCGCGGATCGAACGACAGCCGTTCGTTATATTCACCACGGCG
TACGATCAGTATGCGTTGAAGGCCTTCGAAGTGAACTCGATCGATTACCTGCTGAAGCCGGTCGAGCCCGAGGAACTGGA
CCGCGCATTGAACAAGCTGGAGCAGTTTCAGAACGCCCGCGGCCCAGTCGATCTCCGCGGCGTCTTGGAGGCGCTGTCGC
GCCACGCTCCGGTGCAACGCGTTCCCATTCGAATGGGAGAGCGCACTCGGTTTCTCGAGGTTGGCCGTATCACGCACTTC
TTCACCCAGGGTCGGCTGACCTTCGCCGCGGCGGACGGTAAGACCCATGCGGTCGATTGTACGATCGCCGAGTTGGAGCA
GAAGCTCGGGCCGTCGCGGTTCTTTCGCATTCATCGCGGGACTTTAGTGAATCTGGATTGGCTGGAGGAGCTGACACCGT
GGTTTACAGGCCGCATGGCGGCTCGGCTAAAAGATGAGAAGCGGACGGAGTTAATTGTGGCGCGGGATCGAGTGCGCCTG
CTGAAACGCCATCTCGGCCTTTAA

Upstream 100 bases:

>100_bases
ACTTACAACAGCGGCTGGTGACGATGTTTGGGCCCGGCGCAAGGCTGGAGATTCGAGGCGGCCCGACCGTCTCGTTCTGC
GTTCCACGCGGGTAACCTCC

Downstream 100 bases:

>100_bases
CGAGGTTCGTCGAGATTCGAAAGGAAAGCGGTTTTGTTCAAGCGGCAATCGGAAGCCTTCTTGCATGTCCACTGTGGGGG
AGCTGGAACATGCAGTAATC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MFRAYLVDDELPAVKRLARLLQATGRVEIVGAEMNPVAAIEAIRVASPDILFLDIQMPGLTGFDLLARIERQPFVIFTTA
YDQYALKAFEVNSIDYLLKPVEPEELDRALNKLEQFQNARGPVDLRGVLEALSRHAPVQRVPIRMGERTRFLEVGRITHF
FTQGRLTFAAADGKTHAVDCTIAELEQKLGPSRFFRIHRGTLVNLDWLEELTPWFTGRMAARLKDEKRTELIVARDRVRL
LKRHLGL

Sequences:

>Translated_247_residues
MFRAYLVDDELPAVKRLARLLQATGRVEIVGAEMNPVAAIEAIRVASPDILFLDIQMPGLTGFDLLARIERQPFVIFTTA
YDQYALKAFEVNSIDYLLKPVEPEELDRALNKLEQFQNARGPVDLRGVLEALSRHAPVQRVPIRMGERTRFLEVGRITHF
FTQGRLTFAAADGKTHAVDCTIAELEQKLGPSRFFRIHRGTLVNLDWLEELTPWFTGRMAARLKDEKRTELIVARDRVRL
LKRHLGL
>Mature_247_residues
MFRAYLVDDELPAVKRLARLLQATGRVEIVGAEMNPVAAIEAIRVASPDILFLDIQMPGLTGFDLLARIERQPFVIFTTA
YDQYALKAFEVNSIDYLLKPVEPEELDRALNKLEQFQNARGPVDLRGVLEALSRHAPVQRVPIRMGERTRFLEVGRITHF
FTQGRLTFAAADGKTHAVDCTIAELEQKLGPSRFFRIHRGTLVNLDWLEELTPWFTGRMAARLKDEKRTELIVARDRVRL
LKRHLGL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=260, Percent_Identity=32.3076923076923, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788724, Length=256, Percent_Identity=29.296875, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28202; Mature: 28202

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRAYLVDDELPAVKRLARLLQATGRVEIVGAEMNPVAAIEAIRVASPDILFLDIQMPGL
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHEECCCCEEEEEEECCCC
TGFDLLARIERQPFVIFTTAYDQYALKAFEVNSIDYLLKPVEPEELDRALNKLEQFQNAR
CHHHHHHHHCCCCEEEEEECCCCHHHEEEEECCHHHEECCCCHHHHHHHHHHHHHHHCCC
GPVDLRGVLEALSRHAPVQRVPIRMGERTRFLEVGRITHFFTQGRLTFAAADGKTHAVDC
CCCHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHEECCEEEEEECCCCCEEEEE
TIAELEQKLGPSRFFRIHRGTLVNLDWLEELTPWFTGRMAARLKDEKRTELIVARDRVRL
EHHHHHHHCCHHHEEEEECCCEECHHHHHHHCHHHHHHHHHHHHHCCHHHEEHHHHHHHH
LKRHLGL
HHHHHCC
>Mature Secondary Structure
MFRAYLVDDELPAVKRLARLLQATGRVEIVGAEMNPVAAIEAIRVASPDILFLDIQMPGL
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHEECCCCEEEEEEECCCC
TGFDLLARIERQPFVIFTTAYDQYALKAFEVNSIDYLLKPVEPEELDRALNKLEQFQNAR
CHHHHHHHHCCCCEEEEEECCCCHHHEEEEECCHHHEECCCCHHHHHHHHHHHHHHHCCC
GPVDLRGVLEALSRHAPVQRVPIRMGERTRFLEVGRITHFFTQGRLTFAAADGKTHAVDC
CCCHHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHHHEECCEEEEEECCCCCEEEEE
TIAELEQKLGPSRFFRIHRGTLVNLDWLEELTPWFTGRMAARLKDEKRTELIVARDRVRL
EHHHHHHHCCHHHEEEEECCCEECHHHHHHHCHHHHHHHHHHHHHCCHHHEEHHHHHHHH
LKRHLGL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]