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The map label for this gene is kdsC [H]

Identifier: 116621364

GI number: 116621364

Start: 2869790

End: 2870308

Strand: Reverse

Name: kdsC [H]

Synonym: Acid_2245

Alternate gene names: 116621364

Gene position: 2870308-2869790 (Counterclockwise)

Preceding gene: 116621365

Following gene: 116621363

Centisome position: 28.8

GC content: 64.93

Gene sequence:

>519_bases
ATGGCCGCGATCAAGGCGATTGCCTTGGATGTGGATGGCGTGCTCACCGACGGCGGAGTGTGGTGGGGACCCGACGGCGC
GGAGTGGAAGCGCTTTTGCTTCGCCGACATCATGGGTGTCTCCCTGGCCCGAAAGGCCGGCCTGATCGTCACTCTCATTT
CCGGCGAAGACAGCCCGTTGGTGGACCGCTTCGCCGCCAAAATGAATCTCTCCGACATCACCAAGGGCTGCAAGGATAAA
GCCGCAGCCCTGCGCGCCTTCGCTGCGCGCCAGAGTCTCGCGCTCGAAGAAATCTGTTTCATGGGCGATGATGTCAACGA
CCTGGCCGCGATGGAACTGGCTGGATTCTCCGCCGCGCCGGCGTCGGCCCACGAAGCTGCCCGCCGCACTGCCGGCTTCG
TCACCGCCGCCGCTGGAGGCAACGGCGCCGTCCGCGAACTGGTGGACCGCGTCCTGGCTGCCACACCTCCCGTTAATGCA
AGTCCGTCTGAACGCTCCGATGCGGTGGCCGGGAGTTAA

Upstream 100 bases:

>100_bases
GGCTGGTGGAGCAATCGATGGGTGACGGACAAAAGACCGTAATCGAGCGCGAGAGGCCGATCATCCAGAAACTCCGCCGC
ATTGGCGCCAAGGCCTCTTG

Downstream 100 bases:

>100_bases
TTTCGTAAAATCCTCACTGGGAGAGATCAACTTGGCAATCAATCCTGTCCGCCCATTCCGGATTTTCCAACTGATCGAGT
CGCTGCCGGCTGAGCGGATC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MAAIKAIALDVDGVLTDGGVWWGPDGAEWKRFCFADIMGVSLARKAGLIVTLISGEDSPLVDRFAAKMNLSDITKGCKDK
AAALRAFAARQSLALEEICFMGDDVNDLAAMELAGFSAAPASAHEAARRTAGFVTAAAGGNGAVRELVDRVLAATPPVNA
SPSERSDAVAGS

Sequences:

>Translated_172_residues
MAAIKAIALDVDGVLTDGGVWWGPDGAEWKRFCFADIMGVSLARKAGLIVTLISGEDSPLVDRFAAKMNLSDITKGCKDK
AAALRAFAARQSLALEEICFMGDDVNDLAAMELAGFSAAPASAHEAARRTAGFVTAAAGGNGAVRELVDRVLAATPPVNA
SPSERSDAVAGS
>Mature_171_residues
AAIKAIALDVDGVLTDGGVWWGPDGAEWKRFCFADIMGVSLARKAGLIVTLISGEDSPLVDRFAAKMNLSDITKGCKDKA
AALRAFAARQSLALEEICFMGDDVNDLAAMELAGFSAAPASAHEAARRTAGFVTAAAGGNGAVRELVDRVLAATPPVNAS
PSERSDAVAGS

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=167, Percent_Identity=29.940119760479, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI2367202, Length=161, Percent_Identity=34.1614906832298, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 17681; Mature: 17550

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIKAIALDVDGVLTDGGVWWGPDGAEWKRFCFADIMGVSLARKAGLIVTLISGEDSPL
CCCCEEEEEECCCEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
VDRFAAKMNLSDITKGCKDKAAALRAFAARQSLALEEICFMGDDVNDLAAMELAGFSAAP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ASAHEAARRTAGFVTAAAGGNGAVRELVDRVLAATPPVNASPSERSDAVAGS
CHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAIKAIALDVDGVLTDGGVWWGPDGAEWKRFCFADIMGVSLARKAGLIVTLISGEDSPL
CCCEEEEEECCCEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHH
VDRFAAKMNLSDITKGCKDKAAALRAFAARQSLALEEICFMGDDVNDLAAMELAGFSAAP
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
ASAHEAARRTAGFVTAAAGGNGAVRELVDRVLAATPPVNASPSERSDAVAGS
CHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]