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The map label for this gene is yodQ [H]

Identifier: 116621343

GI number: 116621343

Start: 2846717

End: 2847868

Strand: Reverse

Name: yodQ [H]

Synonym: Acid_2224

Alternate gene names: 116621343

Gene position: 2847868-2846717 (Counterclockwise)

Preceding gene: 116621348

Following gene: 116621334

Centisome position: 28.58

GC content: 67.88

Gene sequence:

>1152_bases
ATGAAAATCGACCGCGAATATACGCTGGCGACCCTCGCACGGCTCGTCCAGATCAATTCCATCAATCCGACGCTCGCACC
GGGTGCTCCGGGAGAGGCCGAGATCGCCGCATTCATTGCGGATTCCCTGCGCGCCAGCGGTCTCACTGCGGAAATCCTGG
AGCCCGAGCCCGGGCGCACCAGCGTCCTTGGGCGACTCGCGGGAACCGGGGGCGGCCGCAGCCTGATGCTGAACGCCCAC
TGCGATACCGTAGATGTCGCCGGCATGGCGGAGCCTTTCAGCGGCGCCATGCGCGACGGCAAACTCTACGGCCGCGGCTC
TTACGATATGAAGGGTTCCCTCGCCGCGTGCATGGCGGCGGCCAAGGCGCTCAAGGACTCCGGCGCGGTGCTGCGCGGTG
ATGTGCTGGTGGCCGCCGTTGCCGATGAGGAGTACGGCAGCCTCGGCACCAGCGACATGATCCCGCACGCAAAAGTGGAT
GGCGCCATCGTCACCGAACCCACGGCGCTCGAAGTTTGCCTGGCCCACAAAGGCTACCTCTGGATCCAGGTCGAGATGAC
GGGCCGCGCCGCGCACGGCAGCAAGTTTCAGTTCGGGATCGACGCCAACATGAAGATGGGCCGGTTCCTCGCCCGGCTCA
GCGAACTGGAGGGCGACCTTCGCGCCCGTCCGCCGCATCCGCTGGTTGGGCCGCCGTCCCTGCATGCGGCCATGCTCAAT
GGCGGATCGGGACTGAGCACGTACGCGGCCTCCTGCACGCTGCAGATCGAGCGGCGCACGGTACCCGGCGAGACCGAACA
GCAGGCCACCGCGGAGATCCAGGCAATCGTGGATGGGCTGGCCGCGGCCGACCCCGATTTCCACGCCACCGTGCGCACGT
TCTTCGTGCGCGACCCGTTCGAGGTGCCGGCGAATGCGCGTGTCGTGCAGGCGGTGGATCGCGCGGCCGCCAAAGTGCGC
GGCGTCGCTCCGGCGCATATCGGCGACACTCCGTGGATGGACGCCGCCCTACTGCAGGCTGCGGGCGTGGAGACCGTGGT
CTTCGGGGCGGCTGGCGCCGGCGCGCACGCCGACGTGGAATGGGTGGACGTGGAATCCGTCGTGCAACTCGCCGAGATTC
TGGCTGAGGCCGCGATCGATTACTGCGGGTGA

Upstream 100 bases:

>100_bases
TCTGTTTCATGTACGCATCCGTGACCCAGCGAATAGACACTATCAAAAAAACCGCCGCTCGGCTACGGCAGGGTGTTTAG
TACCATCGCATTGGAGTCCA

Downstream 100 bases:

>100_bases
CGGCCTCCAAGCAAATTACCAAGCGATCTCGCGGTACGGCCGGGAGGCCTCGTCTACCGGCCCATCCAGCCGCCGTCCAC
CGTTATCACCGTGCCGCTGA

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKIDREYTLATLARLVQINSINPTLAPGAPGEAEIAAFIADSLRASGLTAEILEPEPGRTSVLGRLAGTGGGRSLMLNAH
CDTVDVAGMAEPFSGAMRDGKLYGRGSYDMKGSLAACMAAAKALKDSGAVLRGDVLVAAVADEEYGSLGTSDMIPHAKVD
GAIVTEPTALEVCLAHKGYLWIQVEMTGRAAHGSKFQFGIDANMKMGRFLARLSELEGDLRARPPHPLVGPPSLHAAMLN
GGSGLSTYAASCTLQIERRTVPGETEQQATAEIQAIVDGLAAADPDFHATVRTFFVRDPFEVPANARVVQAVDRAAAKVR
GVAPAHIGDTPWMDAALLQAAGVETVVFGAAGAGAHADVEWVDVESVVQLAEILAEAAIDYCG

Sequences:

>Translated_383_residues
MKIDREYTLATLARLVQINSINPTLAPGAPGEAEIAAFIADSLRASGLTAEILEPEPGRTSVLGRLAGTGGGRSLMLNAH
CDTVDVAGMAEPFSGAMRDGKLYGRGSYDMKGSLAACMAAAKALKDSGAVLRGDVLVAAVADEEYGSLGTSDMIPHAKVD
GAIVTEPTALEVCLAHKGYLWIQVEMTGRAAHGSKFQFGIDANMKMGRFLARLSELEGDLRARPPHPLVGPPSLHAAMLN
GGSGLSTYAASCTLQIERRTVPGETEQQATAEIQAIVDGLAAADPDFHATVRTFFVRDPFEVPANARVVQAVDRAAAKVR
GVAPAHIGDTPWMDAALLQAAGVETVVFGAAGAGAHADVEWVDVESVVQLAEILAEAAIDYCG
>Mature_383_residues
MKIDREYTLATLARLVQINSINPTLAPGAPGEAEIAAFIADSLRASGLTAEILEPEPGRTSVLGRLAGTGGGRSLMLNAH
CDTVDVAGMAEPFSGAMRDGKLYGRGSYDMKGSLAACMAAAKALKDSGAVLRGDVLVAAVADEEYGSLGTSDMIPHAKVD
GAIVTEPTALEVCLAHKGYLWIQVEMTGRAAHGSKFQFGIDANMKMGRFLARLSELEGDLRARPPHPLVGPPSLHAAMLN
GGSGLSTYAASCTLQIERRTVPGETEQQATAEIQAIVDGLAAADPDFHATVRTFFVRDPFEVPANARVVQAVDRAAAKVR
GVAPAHIGDTPWMDAALLQAAGVETVVFGAAGAGAHADVEWVDVESVVQLAEILAEAAIDYCG

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=369, Percent_Identity=26.5582655826558, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789236, Length=253, Percent_Identity=28.0632411067194, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788816, Length=361, Percent_Identity=23.2686980609418, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551016, Length=258, Percent_Identity=27.1317829457364, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 39871; Mature: 39871

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDREYTLATLARLVQINSINPTLAPGAPGEAEIAAFIADSLRASGLTAEILEPEPGRT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
SVLGRLAGTGGGRSLMLNAHCDTVDVAGMAEPFSGAMRDGKLYGRGSYDMKGSLAACMAA
HHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
AKALKDSGAVLRGDVLVAAVADEEYGSLGTSDMIPHAKVDGAIVTEPTALEVCLAHKGYL
HHHHHCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHEEECCCEE
WIQVEMTGRAAHGSKFQFGIDANMKMGRFLARLSELEGDLRARPPHPLVGPPSLHAAMLN
EEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHEEEC
GGSGLSTYAASCTLQIERRTVPGETEQQATAEIQAIVDGLAAADPDFHATVRTFFVRDPF
CCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCC
EVPANARVVQAVDRAAAKVRGVAPAHIGDTPWMDAALLQAAGVETVVFGAAGAGAHADVE
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEE
WVDVESVVQLAEILAEAAIDYCG
EECHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIDREYTLATLARLVQINSINPTLAPGAPGEAEIAAFIADSLRASGLTAEILEPEPGRT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHH
SVLGRLAGTGGGRSLMLNAHCDTVDVAGMAEPFSGAMRDGKLYGRGSYDMKGSLAACMAA
HHHHHHHCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
AKALKDSGAVLRGDVLVAAVADEEYGSLGTSDMIPHAKVDGAIVTEPTALEVCLAHKGYL
HHHHHCCCCEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHEEECCCEE
WIQVEMTGRAAHGSKFQFGIDANMKMGRFLARLSELEGDLRARPPHPLVGPPSLHAAMLN
EEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHEEEC
GGSGLSTYAASCTLQIERRTVPGETEQQATAEIQAIVDGLAAADPDFHATVRTFFVRDPF
CCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEECCC
EVPANARVVQAVDRAAAKVRGVAPAHIGDTPWMDAALLQAAGVETVVFGAAGAGAHADVE
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEE
WVDVESVVQLAEILAEAAIDYCG
EECHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Glutathione. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]