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The map label for this gene is yfiI [H]

Identifier: 116621334

GI number: 116621334

Start: 2838301

End: 2839461

Strand: Reverse

Name: yfiI [H]

Synonym: Acid_2215

Alternate gene names: 116621334

Gene position: 2839461-2838301 (Counterclockwise)

Preceding gene: 116621343

Following gene: 116621329

Centisome position: 28.49

GC content: 60.64

Gene sequence:

>1161_bases
ATGCGAAAATTCAAGACTGCTTTATTCGGAACCGGCTTTGTCGGCCGGGTTCATCTGGAAGGGATTCGCCGCCTGGGCTA
CGTGCAGCTTTATGCCATCGGCGAACCGCAAATCGAGAAGGCCAACCAGCTCGCCGCCGAGTTTGGAGCCGAGAGGACCG
AGGCGGATTATCGCCGCATCCTGGAAGATCCGGCCGTTGACGCCGTTCACATCTGCACCCCTAACGCGCTTCATTTTCCG
ATCGCGAAGGATGCCCTGCAGGCCGGAAAACACGTGATCTGCGAAAAGCCCCTTGCCACCTCCGTTGCGCAAGCCCAGGA
GCTGGTCAAGATCGCCGCTGAAACCAAGCGCCGCAACTGCACCTTCCACAATCTTCGCTTCTACCCCATGGTGCAGCATA
TGCGCCGCATGGTCGAAGATGGCGATCTCGGCAACATCATGGTCGTGCAAGGCACCTACTCGCAGGACTGGCTGCTCTAC
GATACCGATTGGAACTGGCGCCTCGACAGCAAATTTAACGGCCCCTCGCGCTGCCTGGCCGATATCGGCTCGCACTGGTG
CGATATGGCGGAGCACGTCACCGGACAGCGCATCACCAGCGTCTGCGCCGATCTCGCCACCTTCCACAAGACCCGCAAAC
AGCCCAAGGGACCGATCGAAACCTTCGCCGGCAAAACGCTCAGCCCCGACGACTACATCGAAACTCCCATCGATACCGAG
GACATGGGCGCGGTGGTCTTCCGTATGGGCAACGGCGCGCGCGGCGCCTTCACCGCCAGCCAGGTTTCCGCAGGCTGCAA
GAATCGCCTCAGCATCGAGATCTTCGGCAGCAAGAGCGGTGTGATGTGGAACCAGGAGCGTCCCGACGAACTCTGGATCG
GCAACCGCAACACCAACAACCAGATCATCATCAAGGACCCGTCGCTCCTCAAGCCCGCCGCCAAGAGCTTCGCCGATCTT
CCCGGCGGCCACAGCGAAGGCTACGACGATACGTTCAAGCAGGTCTTCCGCCGCTTCTACAAATCCATCGAAGAGCCCGA
CGCGAAGCCCGAGTACCCGCAGTTCGTCGATGGCCTGCGCCAGCTCAGCATTCTCGAAGCTGAACTCGAAAGTAACGCCA
AACACGGCTGGGCCGACGTCCCGCCCTTCCAGGCGGCGTAA

Upstream 100 bases:

>100_bases
TTGGGGCCCTTGCCGAAACGAATCCTTACCACCATGGGAATGTGATTACCAATCTAACAGTTTTTGCGATAGATTATACG
TTCGGAACGCGAAGACGATC

Downstream 100 bases:

>100_bases
TCCCGATGCGCGGCGCAGTGCTCTTGTTCCTGGCAATGGCAAATTGCGCCGCGCAAACATTCCCCGATTTCGCGGGAACA
TGGGTGCAGAGCGTCGAAGG

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRKFKTALFGTGFVGRVHLEGIRRLGYVQLYAIGEPQIEKANQLAAEFGAERTEADYRRILEDPAVDAVHICTPNALHFP
IAKDALQAGKHVICEKPLATSVAQAQELVKIAAETKRRNCTFHNLRFYPMVQHMRRMVEDGDLGNIMVVQGTYSQDWLLY
DTDWNWRLDSKFNGPSRCLADIGSHWCDMAEHVTGQRITSVCADLATFHKTRKQPKGPIETFAGKTLSPDDYIETPIDTE
DMGAVVFRMGNGARGAFTASQVSAGCKNRLSIEIFGSKSGVMWNQERPDELWIGNRNTNNQIIIKDPSLLKPAAKSFADL
PGGHSEGYDDTFKQVFRRFYKSIEEPDAKPEYPQFVDGLRQLSILEAELESNAKHGWADVPPFQAA

Sequences:

>Translated_386_residues
MRKFKTALFGTGFVGRVHLEGIRRLGYVQLYAIGEPQIEKANQLAAEFGAERTEADYRRILEDPAVDAVHICTPNALHFP
IAKDALQAGKHVICEKPLATSVAQAQELVKIAAETKRRNCTFHNLRFYPMVQHMRRMVEDGDLGNIMVVQGTYSQDWLLY
DTDWNWRLDSKFNGPSRCLADIGSHWCDMAEHVTGQRITSVCADLATFHKTRKQPKGPIETFAGKTLSPDDYIETPIDTE
DMGAVVFRMGNGARGAFTASQVSAGCKNRLSIEIFGSKSGVMWNQERPDELWIGNRNTNNQIIIKDPSLLKPAAKSFADL
PGGHSEGYDDTFKQVFRRFYKSIEEPDAKPEYPQFVDGLRQLSILEAELESNAKHGWADVPPFQAA
>Mature_386_residues
MRKFKTALFGTGFVGRVHLEGIRRLGYVQLYAIGEPQIEKANQLAAEFGAERTEADYRRILEDPAVDAVHICTPNALHFP
IAKDALQAGKHVICEKPLATSVAQAQELVKIAAETKRRNCTFHNLRFYPMVQHMRRMVEDGDLGNIMVVQGTYSQDWLLY
DTDWNWRLDSKFNGPSRCLADIGSHWCDMAEHVTGQRITSVCADLATFHKTRKQPKGPIETFAGKTLSPDDYIETPIDTE
DMGAVVFRMGNGARGAFTASQVSAGCKNRLSIEIFGSKSGVMWNQERPDELWIGNRNTNNQIIIKDPSLLKPAAKSFADL
PGGHSEGYDDTFKQVFRRFYKSIEEPDAKPEYPQFVDGLRQLSILEAELESNAKHGWADVPPFQAA

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI9506675, Length=382, Percent_Identity=22.5130890052356, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081947, Length=157, Percent_Identity=31.8471337579618, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787574, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789848, Length=176, Percent_Identity=28.9772727272727, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI145693182, Length=143, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24581117, Length=125, Percent_Identity=28.8, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43295; Mature: 43295

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFKTALFGTGFVGRVHLEGIRRLGYVQLYAIGEPQIEKANQLAAEFGAERTEADYRRI
CCCHHHHHHCCCCEEHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHH
LEDPAVDAVHICTPNALHFPIAKDALQAGKHVICEKPLATSVAQAQELVKIAAETKRRNC
HHCCCCCEEEEECCCCEECCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
TFHNLRFYPMVQHMRRMVEDGDLGNIMVVQGTYSQDWLLYDTDWNWRLDSKFNGPSRCLA
CEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCEEECCCCCCHHHHHH
DIGSHWCDMAEHVTGQRITSVCADLATFHKTRKQPKGPIETFAGKTLSPDDYIETPIDTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHCCCCCCCCC
DMGAVVFRMGNGARGAFTASQVSAGCKNRLSIEIFGSKSGVMWNQERPDELWIGNRNTNN
CCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCC
QIIIKDPSLLKPAAKSFADLPGGHSEGYDDTFKQVFRRFYKSIEEPDAKPEYPQFVDGLR
EEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QLSILEAELESNAKHGWADVPPFQAA
HHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRKFKTALFGTGFVGRVHLEGIRRLGYVQLYAIGEPQIEKANQLAAEFGAERTEADYRRI
CCCHHHHHHCCCCEEHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHH
LEDPAVDAVHICTPNALHFPIAKDALQAGKHVICEKPLATSVAQAQELVKIAAETKRRNC
HHCCCCCEEEEECCCCEECCCHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCC
TFHNLRFYPMVQHMRRMVEDGDLGNIMVVQGTYSQDWLLYDTDWNWRLDSKFNGPSRCLA
CEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCEEECCCCCCHHHHHH
DIGSHWCDMAEHVTGQRITSVCADLATFHKTRKQPKGPIETFAGKTLSPDDYIETPIDTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCHHCCCCCCCCC
DMGAVVFRMGNGARGAFTASQVSAGCKNRLSIEIFGSKSGVMWNQERPDELWIGNRNTNN
CCCEEEEEECCCCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCC
QIIIKDPSLLKPAAKSFADLPGGHSEGYDDTFKQVFRRFYKSIEEPDAKPEYPQFVDGLR
EEEEECCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QLSILEAELESNAKHGWADVPPFQAA
HHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8973323; 9384377 [H]