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The map label for this gene is atoS [C]

Identifier: 116621163

GI number: 116621163

Start: 2590469

End: 2592070

Strand: Reverse

Name: atoS [C]

Synonym: Acid_2044

Alternate gene names: 116621163

Gene position: 2592070-2590469 (Counterclockwise)

Preceding gene: 116621167

Following gene: 116621162

Centisome position: 26.01

GC content: 60.61

Gene sequence:

>1602_bases
GTGCCTCGTTTGCTAACAGACCGGGGAATGGGAAACGGCAATTCTTGGAGAGTCCTGATTATCGAAGATGAAAGCATCGA
TCGGGAGATCTACAAGCGGTACCTCGGCTGCTCCAGCGCCTTCCATTTTGAATTTGCGGAATCCGATTCGGCGGCCGGCG
GCATCGAAATCTCCCGTAGCTGGCAGCCCGACTGTATTCTCCTGGACTTCAATCTTAAGGATATGGACGGTCTCGAAGTC
CTCCCCAGACTGCGCAACGGCGGGGAGCACTTGCCGTGCGCGGTCGTTATGCTGACCGCGTTCGGCGGCGAGGAGCTGGC
CGTGAAGGCCATGAAAAACGGCGCCATGGACTACTTGCCGAAAGGCCAGGTGGTCGGCGACCTTCTGCCGCAGACCGTGG
TGAACGCCATCCGCCGTTTCGAACTGCAGCGCCGCATCGAGCAGCAGCGCGTGGAACTCGAGCGGCGCACCCTGCAATAC
CAGACCCTGCTCGAGGCTATCCCACAAAAAGTATGGACCGCCGACTCCGAGGGGCGGGTCGAATACGCCAACTCCCAGTG
GTCCGAATTTACCGGCCTTGATGCCGTGCGCGCTGGCGAATTGGGATGGGACGACCTGGTCCATCCCGACGACCGCGAGA
ATACCTGGAGCGCATGGAATCAGGCCCGCCAGACCGGCACCATTTTCGAGATTGAACACCGCTTGCGCCGCGCCTCCGAC
GGAGCCTACTGCTGGCACCTGGCGCGCGCAGTCCCCTTCCGCGCGGCCAACGGCCAGATCGTCAACTGGTTCGGCACCTG
TACCGAAATCGAAAATCAAAAACAGGCCGAGACGCTCAATCTCCAGCGCGAGAAACTACAGAGCCTCGGACAACTCGCCG
CCGGACTCGCGCACGATTTCAATAACCTGCTCGTCGCGGTGCTCTGTGGCGCCAGCTATGCGAGGGAAACCCTGCCACCC
ACCCATCCCGTGCAGGAGATCCTCAAAGGCGTGATTCGGGCCGGCGAACGCGCAGCCGAACTGACCAGTAAGATGCTCGC
CTATGCCGGCCTCGGCAATCAGCACATCGAACCGACCGACCTGAACCAGTTGGTGGTGGAAACCTGCGATTCCTTGCGTG
AATCGATCTCCAGGGAAATTTTTCTCGACGTGCAGATCATGCCGGGCGGAGCGCCCCTGACCACGGACCCGCGTCGTATG
CGGCAAGTCGTGGCCGAATTGGTGATGAACGCTGCCGAGTCCATTCGCAAAGGCAGCCCGGGTGTTGTCATCGTCCGCAC
CTACTCACGCGAAATCACCGCGCCTGCGGTATCCGGCCAGCCGCCAGACCTCGCGCCCGGCTGCTATGTGGTCCTGGAAG
TGCATGATAACGGGTGCGGGATGCATGAAGAGATCCTCAAACGGATCTTCGATCCGTTCTTTAGCACTAAGTTTCTTGGC
CGCGGGCTCGGTTTGGCCGCGGTCCAGGGTTTTGTTCGGAGTAATGGCGGCGACGTTCAAGTGGAAAGCAGCCCTGGCGA
CGGTACTTCATTTCGTATATTGTTGCCCACGGCCGAAACCAGCGAGAGCCGCGCAGACCGTGCGACTTGCTCGAGGGGCT
AA

Upstream 100 bases:

>100_bases
TACCCCTCGCTCCGGGCCATCGTAACCCGAACTCTACGCGCCACCCCACCCGACAATGCCGTGGATTGTCCTCGGCCGTA
CATTCCCCTCCGGTGAAACG

Downstream 100 bases:

>100_bases
TTATGTCGGCATCCGACCCGAAAGCTGCACAATCCGCGATCGGGGCGAGGACCGCCTCCCCAAACGACGATTGCAGCATC
CACCTGACCCCTGATGCCCT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MPRLLTDRGMGNGNSWRVLIIEDESIDREIYKRYLGCSSAFHFEFAESDSAAGGIEISRSWQPDCILLDFNLKDMDGLEV
LPRLRNGGEHLPCAVVMLTAFGGEELAVKAMKNGAMDYLPKGQVVGDLLPQTVVNAIRRFELQRRIEQQRVELERRTLQY
QTLLEAIPQKVWTADSEGRVEYANSQWSEFTGLDAVRAGELGWDDLVHPDDRENTWSAWNQARQTGTIFEIEHRLRRASD
GAYCWHLARAVPFRAANGQIVNWFGTCTEIENQKQAETLNLQREKLQSLGQLAAGLAHDFNNLLVAVLCGASYARETLPP
THPVQEILKGVIRAGERAAELTSKMLAYAGLGNQHIEPTDLNQLVVETCDSLRESISREIFLDVQIMPGGAPLTTDPRRM
RQVVAELVMNAAESIRKGSPGVVIVRTYSREITAPAVSGQPPDLAPGCYVVLEVHDNGCGMHEEILKRIFDPFFSTKFLG
RGLGLAAVQGFVRSNGGDVQVESSPGDGTSFRILLPTAETSESRADRATCSRG

Sequences:

>Translated_533_residues
MPRLLTDRGMGNGNSWRVLIIEDESIDREIYKRYLGCSSAFHFEFAESDSAAGGIEISRSWQPDCILLDFNLKDMDGLEV
LPRLRNGGEHLPCAVVMLTAFGGEELAVKAMKNGAMDYLPKGQVVGDLLPQTVVNAIRRFELQRRIEQQRVELERRTLQY
QTLLEAIPQKVWTADSEGRVEYANSQWSEFTGLDAVRAGELGWDDLVHPDDRENTWSAWNQARQTGTIFEIEHRLRRASD
GAYCWHLARAVPFRAANGQIVNWFGTCTEIENQKQAETLNLQREKLQSLGQLAAGLAHDFNNLLVAVLCGASYARETLPP
THPVQEILKGVIRAGERAAELTSKMLAYAGLGNQHIEPTDLNQLVVETCDSLRESISREIFLDVQIMPGGAPLTTDPRRM
RQVVAELVMNAAESIRKGSPGVVIVRTYSREITAPAVSGQPPDLAPGCYVVLEVHDNGCGMHEEILKRIFDPFFSTKFLG
RGLGLAAVQGFVRSNGGDVQVESSPGDGTSFRILLPTAETSESRADRATCSRG
>Mature_532_residues
PRLLTDRGMGNGNSWRVLIIEDESIDREIYKRYLGCSSAFHFEFAESDSAAGGIEISRSWQPDCILLDFNLKDMDGLEVL
PRLRNGGEHLPCAVVMLTAFGGEELAVKAMKNGAMDYLPKGQVVGDLLPQTVVNAIRRFELQRRIEQQRVELERRTLQYQ
TLLEAIPQKVWTADSEGRVEYANSQWSEFTGLDAVRAGELGWDDLVHPDDRENTWSAWNQARQTGTIFEIEHRLRRASDG
AYCWHLARAVPFRAANGQIVNWFGTCTEIENQKQAETLNLQREKLQSLGQLAAGLAHDFNNLLVAVLCGASYARETLPPT
HPVQEILKGVIRAGERAAELTSKMLAYAGLGNQHIEPTDLNQLVVETCDSLRESISREIFLDVQIMPGGAPLTTDPRRMR
QVVAELVMNAAESIRKGSPGVVIVRTYSREITAPAVSGQPPDLAPGCYVVLEVHDNGCGMHEEILKRIFDPFFSTKFLGR
GLGLAAVQGFVRSNGGDVQVESSPGDGTSFRILLPTAETSESRADRATCSRG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=262, Percent_Identity=27.4809160305344, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=31.2236286919831, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=23.9669421487603, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=26.8595041322314, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=424, Percent_Identity=21.9339622641509, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59038; Mature: 58906

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLLTDRGMGNGNSWRVLIIEDESIDREIYKRYLGCSSAFHFEFAESDSAAGGIEISRS
CCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECC
WQPDCILLDFNLKDMDGLEVLPRLRNGGEHLPCAVVMLTAFGGEELAVKAMKNGAMDYLP
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCC
KGQVVGDLLPQTVVNAIRRFELQRRIEQQRVELERRTLQYQTLLEAIPQKVWTADSEGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
EYANSQWSEFTGLDAVRAGELGWDDLVHPDDRENTWSAWNQARQTGTIFEIEHRLRRASD
EECCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GAYCWHLARAVPFRAANGQIVNWFGTCTEIENQKQAETLNLQREKLQSLGQLAAGLAHDF
CHHHHHHHHHCCCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNLLVAVLCGASYARETLPPTHPVQEILKGVIRAGERAAELTSKMLAYAGLGNQHIEPTD
HHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCH
LNQLVVETCDSLRESISREIFLDVQIMPGGAPLTTDPRRMRQVVAELVMNAAESIRKGSP
HHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GVVIVRTYSREITAPAVSGQPPDLAPGCYVVLEVHDNGCGMHEEILKRIFDPFFSTKFLG
CEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RGLGLAAVQGFVRSNGGDVQVESSPGDGTSFRILLPTAETSESRADRATCSRG
CCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
PRLLTDRGMGNGNSWRVLIIEDESIDREIYKRYLGCSSAFHFEFAESDSAAGGIEISRS
CCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECC
WQPDCILLDFNLKDMDGLEVLPRLRNGGEHLPCAVVMLTAFGGEELAVKAMKNGAMDYLP
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCC
KGQVVGDLLPQTVVNAIRRFELQRRIEQQRVELERRTLQYQTLLEAIPQKVWTADSEGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
EYANSQWSEFTGLDAVRAGELGWDDLVHPDDRENTWSAWNQARQTGTIFEIEHRLRRASD
EECCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
GAYCWHLARAVPFRAANGQIVNWFGTCTEIENQKQAETLNLQREKLQSLGQLAAGLAHDF
CHHHHHHHHHCCCCCCCCCEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NNLLVAVLCGASYARETLPPTHPVQEILKGVIRAGERAAELTSKMLAYAGLGNQHIEPTD
HHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCH
LNQLVVETCDSLRESISREIFLDVQIMPGGAPLTTDPRRMRQVVAELVMNAAESIRKGSP
HHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
GVVIVRTYSREITAPAVSGQPPDLAPGCYVVLEVHDNGCGMHEEILKRIFDPFFSTKFLG
CEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RGLGLAAVQGFVRSNGGDVQVESSPGDGTSFRILLPTAETSESRADRATCSRG
CCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA