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The map label for this gene is aphA [H]

Identifier: 116621162

GI number: 116621162

Start: 2589699

End: 2590466

Strand: Reverse

Name: aphA [H]

Synonym: Acid_2043

Alternate gene names: 116621162

Gene position: 2590466-2589699 (Counterclockwise)

Preceding gene: 116621163

Following gene: 116621161

Centisome position: 25.99

GC content: 59.64

Gene sequence:

>768_bases
ATGTCGGCATCCGACCCGAAAGCTGCACAATCCGCGATCGGGGCGAGGACCGCCTCCCCAAACGACGATTGCAGCATCCA
CCTGACCCCTGATGCCCTCCACGACCTCGTTGGGCCGGCGAACCAGTTGCGTTCTATGGCCGACCTGATACTTCGCAAGC
ATCGCGAAAAGCTCGGCGATGACGCAGACGTTTTGTTCGGCTTCATGCAGGCCGCCTCGGACCGGCTGCAGCTTCTGATC
TCGGGCCTGCGCGACCATACCCGGATCATCGGTAACTCGCAGCCGCATCGGAACTTCGATGTCAATGACGTTCTCGAAGG
CGCGTTGGCCACACTGAACCAAACCCTCCAGCAAAACCAGGCGGTGGTGACCCACGACCCTCTCCCGGAAATCTGGGGCG
ATCCCACTCAAATCTGCTACGCCTTCGTAAGCCTGATCGACAACGCTATCAAGTTTCGCGCGAATTCCCCTCCGAAGATC
CACATAGGTGTCTCAGCGTCGGGACCTTCCTGGCTCTTCTCGGTTTGCGACAACGGCATTGGCATTGATCCCAAATATGC
CGACCGGATCTTCGACGTCTTCAAGCGCGTTCATAACGACAGTTATCCCGGAGCCGGGATGGGACTCCCCATTGCCCGGC
GCATCATCGAGCGGCACGGAGGCAGAATTTGGGTGGACTCGGCTTTGGGTAAAGGCGCGTGTTTTTTCTTCACCTTGCCC
AATTTGGCCGGCGGGGAAGTGCCCATTGCGGCCCCGGCGGGAGCGTGA

Upstream 100 bases:

>100_bases
AAAGCAGCCCTGGCGACGGTACTTCATTTCGTATATTGTTGCCCACGGCCGAAACCAGCGAGAGCCGCGCAGACCGTGCG
ACTTGCTCGAGGGGCTAATT

Downstream 100 bases:

>100_bases
CCCGCCGAGTGGAAGAACGCGTGCAACGAATTCTGACGTTCCCAGCGATTCGTGCAATTTCGGTAAAGGACAAGGGCTGC
AGTTTGTCAGGAAGCAAGAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSASDPKAAQSAIGARTASPNDDCSIHLTPDALHDLVGPANQLRSMADLILRKHREKLGDDADVLFGFMQAASDRLQLLI
SGLRDHTRIIGNSQPHRNFDVNDVLEGALATLNQTLQQNQAVVTHDPLPEIWGDPTQICYAFVSLIDNAIKFRANSPPKI
HIGVSASGPSWLFSVCDNGIGIDPKYADRIFDVFKRVHNDSYPGAGMGLPIARRIIERHGGRIWVDSALGKGACFFFTLP
NLAGGEVPIAAPAGA

Sequences:

>Translated_255_residues
MSASDPKAAQSAIGARTASPNDDCSIHLTPDALHDLVGPANQLRSMADLILRKHREKLGDDADVLFGFMQAASDRLQLLI
SGLRDHTRIIGNSQPHRNFDVNDVLEGALATLNQTLQQNQAVVTHDPLPEIWGDPTQICYAFVSLIDNAIKFRANSPPKI
HIGVSASGPSWLFSVCDNGIGIDPKYADRIFDVFKRVHNDSYPGAGMGLPIARRIIERHGGRIWVDSALGKGACFFFTLP
NLAGGEVPIAAPAGA
>Mature_254_residues
SASDPKAAQSAIGARTASPNDDCSIHLTPDALHDLVGPANQLRSMADLILRKHREKLGDDADVLFGFMQAASDRLQLLIS
GLRDHTRIIGNSQPHRNFDVNDVLEGALATLNQTLQQNQAVVTHDPLPEIWGDPTQICYAFVSLIDNAIKFRANSPPKIH
IGVSASGPSWLFSVCDNGIGIDPKYADRIFDVFKRVHNDSYPGAGMGLPIARRIIERHGGRIWVDSALGKGACFFFTLPN
LAGGEVPIAAPAGA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=217, Percent_Identity=28.110599078341, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=172, Percent_Identity=31.9767441860465, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081816, Length=130, Percent_Identity=33.0769230769231, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28.8888888888889, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27464; Mature: 27333

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASDPKAAQSAIGARTASPNDDCSIHLTPDALHDLVGPANQLRSMADLILRKHREKLGD
CCCCCHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
DADVLFGFMQAASDRLQLLISGLRDHTRIIGNSQPHRNFDVNDVLEGALATLNQTLQQNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
AVVTHDPLPEIWGDPTQICYAFVSLIDNAIKFRANSPPKIHIGVSASGPSWLFSVCDNGI
EEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCC
GIDPKYADRIFDVFKRVHNDSYPGAGMGLPIARRIIERHGGRIWVDSALGKGACFFFTLP
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECC
NLAGGEVPIAAPAGA
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SASDPKAAQSAIGARTASPNDDCSIHLTPDALHDLVGPANQLRSMADLILRKHREKLGD
CCCCHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
DADVLFGFMQAASDRLQLLISGLRDHTRIIGNSQPHRNFDVNDVLEGALATLNQTLQQNQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
AVVTHDPLPEIWGDPTQICYAFVSLIDNAIKFRANSPPKIHIGVSASGPSWLFSVCDNGI
EEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCC
GIDPKYADRIFDVFKRVHNDSYPGAGMGLPIARRIIERHGGRIWVDSALGKGACFFFTLP
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECC
NLAGGEVPIAAPAGA
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]