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The map label for this gene is 116621031

Identifier: 116621031

GI number: 116621031

Start: 2373829

End: 2374728

Strand: Direct

Name: 116621031

Synonym: Acid_1912

Alternate gene names: NA

Gene position: 2373829-2374728 (Clockwise)

Preceding gene: 116621030

Following gene: 116621038

Centisome position: 23.82

GC content: 60.89

Gene sequence:

>900_bases
ATGCCAATGCCGCGCCGGCTGTATTACTGCGATCAGCATCCGATTCCGCTGCCGCCGGGCCACAAATTTCCGACTCAAAA
GTACGCGATGCTGCGCTCCAAACTGGAGGCGGAGCACCGCTTCGAACTGACGCCCGCGCCGCCGGCGGAGATAGCGCAGC
TGGAACTGGCCCACGAGGAACAGTACGTGCGCGCGATTCTTCACGGCGATGTGGACCCGCGCGTAATGCGGCGGATTGGA
TTTCCGTGGTCGGAGGCGCTGGTGCGGCGGACGCTCGCATCGGTGGGCGGCACGCTGGCGGCATCGCGGGATGCGATGGA
GTCAGGATTGGGCGGCAACCTCGCGGGCGGAACGCATCACGCCTTTCGGGCTGAAGGCTCGGGCTTCTGCGTCTTTAACG
ACCTGGCAGTCGCGATCCTGATGTTACGGCGCGAAGGACTGGCAGCGCGCGCCGCGGTGATCGATCTGGATGTCCACCAG
GGCGATGGGACGGCCTCGATTTTCGAAAGCGACCCGAGCGTGCTGACGGTCTCGATCCACGGCGAGAACAACTTCCCATT
TCGCAAACAGCGTAGCCGGATCGATATCGGATTATCCGACGGTACCAGTGATGACGAATACATAAGCCACGTTCAGAGCA
TGCTTCCTGTAGTACTCGCGTTCCAACCTGAAGTGATGTTGTATCAAGCGGGAGTAGATGGGTTAGCGAGCGACCGGCTG
GGCCGGCTTGCACTTACTCAGCAGGGACTAGCTCGGCGGGACCGGCTGGTATTGGAAGCGGCGCGTTCCCACCGGATACC
GTTAGTAATCACTCTTGGAGGAGGTTACAGCGAGCCGATCGAGGCCACGGCTGAAGCGCATGCCAACACCTTCCGAATCG
CATCACAAATTTACAAGTGA

Upstream 100 bases:

>100_bases
ATGGTGGAAGGCCCCAACCTAGAGCAGGTGGAGAGCTTTAGCACGAGCATTGCCGACGTGATCCGGCGCGAGATGGGGGA
GTAGCGCGCGCGAGAGACGG

Downstream 100 bases:

>100_bases
AGGCGAGCCTGTGTACTGATGAATCGGACGATTTCACCCCGTTGGGAGCAAAGGACGGGGACATATGCAACCTTATCATT
CATCAGAGCGTCATATGTAT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPMPRRLYYCDQHPIPLPPGHKFPTQKYAMLRSKLEAEHRFELTPAPPAEIAQLELAHEEQYVRAILHGDVDPRVMRRIG
FPWSEALVRRTLASVGGTLAASRDAMESGLGGNLAGGTHHAFRAEGSGFCVFNDLAVAILMLRREGLAARAAVIDLDVHQ
GDGTASIFESDPSVLTVSIHGENNFPFRKQRSRIDIGLSDGTSDDEYISHVQSMLPVVLAFQPEVMLYQAGVDGLASDRL
GRLALTQQGLARRDRLVLEAARSHRIPLVITLGGGYSEPIEATAEAHANTFRIASQIYK

Sequences:

>Translated_299_residues
MPMPRRLYYCDQHPIPLPPGHKFPTQKYAMLRSKLEAEHRFELTPAPPAEIAQLELAHEEQYVRAILHGDVDPRVMRRIG
FPWSEALVRRTLASVGGTLAASRDAMESGLGGNLAGGTHHAFRAEGSGFCVFNDLAVAILMLRREGLAARAAVIDLDVHQ
GDGTASIFESDPSVLTVSIHGENNFPFRKQRSRIDIGLSDGTSDDEYISHVQSMLPVVLAFQPEVMLYQAGVDGLASDRL
GRLALTQQGLARRDRLVLEAARSHRIPLVITLGGGYSEPIEATAEAHANTFRIASQIYK
>Mature_298_residues
PMPRRLYYCDQHPIPLPPGHKFPTQKYAMLRSKLEAEHRFELTPAPPAEIAQLELAHEEQYVRAILHGDVDPRVMRRIGF
PWSEALVRRTLASVGGTLAASRDAMESGLGGNLAGGTHHAFRAEGSGFCVFNDLAVAILMLRREGLAARAAVIDLDVHQG
DGTASIFESDPSVLTVSIHGENNFPFRKQRSRIDIGLSDGTSDDEYISHVQSMLPVVLAFQPEVMLYQAGVDGLASDRLG
RLALTQQGLARRDRLVLEAARSHRIPLVITLGGGYSEPIEATAEAHANTFRIASQIYK

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=273, Percent_Identity=32.6007326007326, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI209862883, Length=198, Percent_Identity=37.3737373737374, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI13128860, Length=211, Percent_Identity=33.175355450237, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI13128862, Length=206, Percent_Identity=33.495145631068, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI8923769, Length=282, Percent_Identity=27.6595744680851, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI293336691, Length=186, Percent_Identity=32.7956989247312, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI13128864, Length=264, Percent_Identity=31.4393939393939, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI262073088, Length=172, Percent_Identity=31.9767441860465, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI20070354, Length=193, Percent_Identity=30.5699481865285, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI30795202, Length=135, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI30795204, Length=135, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI17158039, Length=135, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI169234807, Length=133, Percent_Identity=30.8270676691729, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI148539870, Length=133, Percent_Identity=30.8270676691729, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI62750349, Length=178, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI62750347, Length=178, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI153085395, Length=135, Percent_Identity=31.8518518518519, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI262073092, Length=123, Percent_Identity=36.5853658536585, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508561, Length=211, Percent_Identity=35.5450236966825, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193207430, Length=193, Percent_Identity=32.6424870466321, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17561978, Length=211, Percent_Identity=34.1232227488152, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17534739, Length=259, Percent_Identity=29.3436293436293, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17540332, Length=176, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193206283, Length=186, Percent_Identity=31.7204301075269, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17540334, Length=186, Percent_Identity=31.7204301075269, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=294, Percent_Identity=27.891156462585, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209491, Length=281, Percent_Identity=27.7580071174377, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321244, Length=211, Percent_Identity=32.2274881516588, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323999, Length=261, Percent_Identity=29.5019157088123, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6325325, Length=184, Percent_Identity=32.6086956521739, Blast_Score=98, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6324307, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649807, Length=186, Percent_Identity=33.8709677419355, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24657891, Length=262, Percent_Identity=31.2977099236641, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24644244, Length=203, Percent_Identity=30.5418719211823, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24642144, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24642146, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24642142, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI281360899, Length=176, Percent_Identity=32.3863636363636, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641720, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281360801, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI281360799, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32810; Mature: 32679

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPRRLYYCDQHPIPLPPGHKFPTQKYAMLRSKLEAEHRFELTPAPPAEIAQLELAHEE
CCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEECCCCCHHHHHHHHHHHHH
QYVRAILHGDVDPRVMRRIGFPWSEALVRRTLASVGGTLAASRDAMESGLGGNLAGGTHH
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
AFRAEGSGFCVFNDLAVAILMLRREGLAARAAVIDLDVHQGDGTASIFESDPSVLTVSIH
EEECCCCCEEEEHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCEEEEECCCCEEEEEEE
GENNFPFRKQRSRIDIGLSDGTSDDEYISHVQSMLPVVLAFQPEVMLYQAGVDGLASDRL
CCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
GRLALTQQGLARRDRLVLEAARSHRIPLVITLGGGYSEPIEATAEAHANTFRIASQIYK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PMPRRLYYCDQHPIPLPPGHKFPTQKYAMLRSKLEAEHRFELTPAPPAEIAQLELAHEE
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCHHHEEECCCCCHHHHHHHHHHHHH
QYVRAILHGDVDPRVMRRIGFPWSEALVRRTLASVGGTLAASRDAMESGLGGNLAGGTHH
HHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCC
AFRAEGSGFCVFNDLAVAILMLRREGLAARAAVIDLDVHQGDGTASIFESDPSVLTVSIH
EEECCCCCEEEEHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCEEEEECCCCEEEEEEE
GENNFPFRKQRSRIDIGLSDGTSDDEYISHVQSMLPVVLAFQPEVMLYQAGVDGLASDRL
CCCCCCCHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
GRLALTQQGLARRDRLVLEAARSHRIPLVITLGGGYSEPIEATAEAHANTFRIASQIYK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]