Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 116621030

GI number: 116621030

Start: 2372472

End: 2373812

Strand: Direct

Name: glmM

Synonym: Acid_1911

Alternate gene names: 116621030

Gene position: 2372472-2373812 (Clockwise)

Preceding gene: 116621029

Following gene: 116621031

Centisome position: 23.81

GC content: 64.43

Gene sequence:

>1341_bases
TTGGCAAAAGACTTGTTCGGAACAGATGGGATTCGGGGAGTCGCAGGGCAATACCCGCTGGACCGGGATACGGTCTACGC
GTTTGGCGTCGCGCTTGGCAAGGACGCAGCCCTGCATGCGGCGAAGCCGGAGATCCTGATCGGCGCCGATACACGTGAGA
GCGGGACGTGGATCGCGGAACTGGTGGCGGGCGGCCTGGCGAGCCAGGGAGCGCAGGTGCGCTACGCGGGCGTGATCACC
ACGCCGGGTGTGGCCTACCTGACGCGCACCGGCTCTTTCGTTGCCGGCGTGATGATTTCGGCATCGCACAATCCCTACGA
CGACAACGGGCTGAAAGTCTTCGGGCACAGCGGCTTCAAACTGCCGGACGATGAAGAGCTGCTGATCGAGCAGGAGATCT
TCCGGCTGCGTGAAGCGCCGGTCGCGCCGCAGCCGTTGAGTCTAACCGTGGAAGAGCCGCTGGTACGGCAGTATCTCAAG
TACCTGAGCGGAATTTCCTCGGTGCGGCTGGACGGCGTGCGAGTGGCGATCGATTGCGGCAATGGCGCGTCCTATCGCCT
GGCGCCCGAGTTGTTCCAGGGTCTGGGGGCGGACGTGGTGACCATCTGCTGCGAACCGAACGGACGCAACATCAACCTGA
ATTGCGGCGCGCTCCATTTGGAAGCGCTGCAGCAGGCTGTGGTGGCGCACCGCGCGCATTTCGGCGTGGCGTTCGATGGC
GACGCCGACCGCGCTATTTTCGTTTCGTCAAGCGGGCAGGTGGTGAACGGCGATGCGGTCCTGCTGGCCTGCGGGCGAGC
GTTGAAGGCCGCGGGAAAGCTGGCCGGCAACACGGTGGTTTCCACGGTGATGTCGAATCTGGGGCTGGAGCGGGCCTTCG
ATGCGGCGGGAATTCGCATGGTGCGGACGCCCGTGGGCGATAAATACGTGCTGGAGGAGATGGTGCGGTTGGGCGCGGCG
CTGGGCGGCGAACAATCGGGACACGTGATCTTCCGCGAATACTCGACCACGGGCGACGGCATGCTCACGGCGCTTCGCCT
GTTCGAGATCGCGCAACAGGCGGGCACGGGTCTGGACGAATTGACAGCGGATCTGAAGATCTATCCGCAGCGCCTGGTCA
ATGTGCGAGTGCGCGAGAAAAAGGGTCTGCTGGAACTGCCCGCGGTGGCGAAGGAGATCCGCCGTGTGGAAGACGCCTTC
GGCGGCGCCGGCCGTGTGCTGGTGCGTTTTTCGGGCACCGAGCCTCTCGCACGCGTGATGGTGGAAGGCCCCAACCTAGA
GCAGGTGGAGAGCTTTAGCACGAGCATTGCCGACGTGATCCGGCGCGAGATGGGGGAGTAG

Upstream 100 bases:

>100_bases
CATGTCAATCTGTTCGTGGACGATCCATTCGTACGTTTTGAATCCGCGCCGGAAGCGACGGTGACGGTTTCGATGAAGAA
GAAATAGGCGAGGAGATAGT

Downstream 100 bases:

>100_bases
CGCGCGCGAGAGACGGATGCCAATGCCGCGCCGGCTGTATTACTGCGATCAGCATCCGATTCCGCTGCCGCCGGGCCACA
AATTTCCGACTCAAAAGTAC

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MAKDLFGTDGIRGVAGQYPLDRDTVYAFGVALGKDAALHAAKPEILIGADTRESGTWIAELVAGGLASQGAQVRYAGVIT
TPGVAYLTRTGSFVAGVMISASHNPYDDNGLKVFGHSGFKLPDDEELLIEQEIFRLREAPVAPQPLSLTVEEPLVRQYLK
YLSGISSVRLDGVRVAIDCGNGASYRLAPELFQGLGADVVTICCEPNGRNINLNCGALHLEALQQAVVAHRAHFGVAFDG
DADRAIFVSSSGQVVNGDAVLLACGRALKAAGKLAGNTVVSTVMSNLGLERAFDAAGIRMVRTPVGDKYVLEEMVRLGAA
LGGEQSGHVIFREYSTTGDGMLTALRLFEIAQQAGTGLDELTADLKIYPQRLVNVRVREKKGLLELPAVAKEIRRVEDAF
GGAGRVLVRFSGTEPLARVMVEGPNLEQVESFSTSIADVIRREMGE

Sequences:

>Translated_446_residues
MAKDLFGTDGIRGVAGQYPLDRDTVYAFGVALGKDAALHAAKPEILIGADTRESGTWIAELVAGGLASQGAQVRYAGVIT
TPGVAYLTRTGSFVAGVMISASHNPYDDNGLKVFGHSGFKLPDDEELLIEQEIFRLREAPVAPQPLSLTVEEPLVRQYLK
YLSGISSVRLDGVRVAIDCGNGASYRLAPELFQGLGADVVTICCEPNGRNINLNCGALHLEALQQAVVAHRAHFGVAFDG
DADRAIFVSSSGQVVNGDAVLLACGRALKAAGKLAGNTVVSTVMSNLGLERAFDAAGIRMVRTPVGDKYVLEEMVRLGAA
LGGEQSGHVIFREYSTTGDGMLTALRLFEIAQQAGTGLDELTADLKIYPQRLVNVRVREKKGLLELPAVAKEIRRVEDAF
GGAGRVLVRFSGTEPLARVMVEGPNLEQVESFSTSIADVIRREMGE
>Mature_445_residues
AKDLFGTDGIRGVAGQYPLDRDTVYAFGVALGKDAALHAAKPEILIGADTRESGTWIAELVAGGLASQGAQVRYAGVITT
PGVAYLTRTGSFVAGVMISASHNPYDDNGLKVFGHSGFKLPDDEELLIEQEIFRLREAPVAPQPLSLTVEEPLVRQYLKY
LSGISSVRLDGVRVAIDCGNGASYRLAPELFQGLGADVVTICCEPNGRNINLNCGALHLEALQQAVVAHRAHFGVAFDGD
ADRAIFVSSSGQVVNGDAVLLACGRALKAAGKLAGNTVVSTVMSNLGLERAFDAAGIRMVRTPVGDKYVLEEMVRLGAAL
GGEQSGHVIFREYSTTGDGMLTALRLFEIAQQAGTGLDELTADLKIYPQRLVNVRVREKKGLLELPAVAKEIRRVEDAFG
GAGRVLVRFSGTEPLARVMVEGPNLEQVESFSTSIADVIRREMGE

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=442, Percent_Identity=42.3076923076923, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1788361, Length=448, Percent_Identity=27.4553571428571, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_SOLUE (Q027B2)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_823186.1
- ProteinModelPortal:   Q027B2
- SMR:   Q027B2
- STRING:   Q027B2
- GeneID:   4429900
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_1911
- NMPDR:   fig|234267.9.peg.1819
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- PhylomeDB:   Q027B2
- ProtClustDB:   CLSK774246
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47469; Mature: 47338

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLFGTDGIRGVAGQYPLDRDTVYAFGVALGKDAALHAAKPEILIGADTRESGTWIAE
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHCCCCCCEEEECCCCCCCCHHHH
LVAGGLASQGAQVRYAGVITTPGVAYLTRTGSFVAGVMISASHNPYDDNGLKVFGHSGFK
HHHCHHHCCCCEEEEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEECCCCC
LPDDEELLIEQEIFRLREAPVAPQPLSLTVEEPLVRQYLKYLSGISSVRLDGVRVAIDCG
CCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEECCEEEEEECC
NGASYRLAPELFQGLGADVVTICCEPNGRNINLNCGALHLEALQQAVVAHRAHFGVAFDG
CCCCEEECHHHHHCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEECC
DADRAIFVSSSGQVVNGDAVLLACGRALKAAGKLAGNTVVSTVMSNLGLERAFDAAGIRM
CCCCEEEEECCCCEECCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCEEE
VRTPVGDKYVLEEMVRLGAALGGEQSGHVIFREYSTTGDGMLTALRLFEIAQQAGTGLDE
EECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHH
LTADLKIYPQRLVNVRVREKKGLLELPAVAKEIRRVEDAFGGAGRVLVRFSGTEPLARVM
HHHHHHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHE
VEGPNLEQVESFSTSIADVIRREMGE
ECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKDLFGTDGIRGVAGQYPLDRDTVYAFGVALGKDAALHAAKPEILIGADTRESGTWIAE
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHCCCCCCEEEECCCCCCCCHHHH
LVAGGLASQGAQVRYAGVITTPGVAYLTRTGSFVAGVMISASHNPYDDNGLKVFGHSGFK
HHHCHHHCCCCEEEEEEEEECCCEEEEECCCCEEEEEEEECCCCCCCCCCEEEEECCCCC
LPDDEELLIEQEIFRLREAPVAPQPLSLTVEEPLVRQYLKYLSGISSVRLDGVRVAIDCG
CCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHCCCCCEEECCEEEEEECC
NGASYRLAPELFQGLGADVVTICCEPNGRNINLNCGALHLEALQQAVVAHRAHFGVAFDG
CCCCEEECHHHHHCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEECC
DADRAIFVSSSGQVVNGDAVLLACGRALKAAGKLAGNTVVSTVMSNLGLERAFDAAGIRM
CCCCEEEEECCCCEECCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCEEE
VRTPVGDKYVLEEMVRLGAALGGEQSGHVIFREYSTTGDGMLTALRLFEIAQQAGTGLDE
EECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHH
LTADLKIYPQRLVNVRVREKKGLLELPAVAKEIRRVEDAFGGAGRVLVRFSGTEPLARVM
HHHHHHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHE
VEGPNLEQVESFSTSIADVIRREMGE
ECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA