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The map label for this gene is fur [H]

Identifier: 116620976

GI number: 116620976

Start: 2312330

End: 2312854

Strand: Reverse

Name: fur [H]

Synonym: Acid_1857

Alternate gene names: 116620976

Gene position: 2312854-2312330 (Counterclockwise)

Preceding gene: 116620979

Following gene: 116620975

Centisome position: 23.21

GC content: 62.29

Gene sequence:

>525_bases
ATGGCGCTCGACTCAATTGAAGGATCCCTGAAAGAGCGGGGCGTGCGTCTCACGCGCCAACGGCAGATATTGCTGGAGCT
GATCGATACCACCGGCGAGCACCTGGATGCCGAGCGGCTCTACCAAATGGCGAAGGAAAAGGACCCGAAGCTCAACCGGG
TCACTGTCTATCGCACCCTCAAGATGCTCAAGGCCGGCGGCTTGGTGGATGAGCTGGACCTCATGCACTACGGCGGTGAT
CAGCACTACTACGAGACCCGGCTCAAACAGGAACATGCTCATGTGATCTGCCTCCGCTGCGGCAAGGTCGAAGAATTCTT
CGGCGAACCGCTGCAGCGGCTGCGTAAACAGATCGAAAGCCACTTCGGATTTCAGGTGCTGCTGGCGCGCACCGAAGTCG
GCGGGTACTGCGCCCACTGCCAGACGCTGCGCGCGCGGGAAGTTGAGGAGCTCCGGGTGTTGACGGCCGACGCCGCCAAG
CCGCCGGCTACCAAATCGCGGCGCGCCCGAACCCGGCGAAGCTGA

Upstream 100 bases:

>100_bases
GTTGGCGATCAAGACCTTACGGAACATGCAGAAGGAATTGTAGCAGCCGCCGCACGGCAGGGCCTCACTGGGCTAGAATT
GAAAAGTCTCCGGAAGAACT

Downstream 100 bases:

>100_bases
ATGGAACCGGAAGCCGCGATTGTTCCCACGGTAGGTCCGGCCTCGCTGGTCGTGGTGGACCCCAATGGACAAAAGAAGCG
CGTGCCGCTGGACCAGAACC

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MALDSIEGSLKERGVRLTRQRQILLELIDTTGEHLDAERLYQMAKEKDPKLNRVTVYRTLKMLKAGGLVDELDLMHYGGD
QHYYETRLKQEHAHVICLRCGKVEEFFGEPLQRLRKQIESHFGFQVLLARTEVGGYCAHCQTLRAREVEELRVLTADAAK
PPATKSRRARTRRS

Sequences:

>Translated_174_residues
MALDSIEGSLKERGVRLTRQRQILLELIDTTGEHLDAERLYQMAKEKDPKLNRVTVYRTLKMLKAGGLVDELDLMHYGGD
QHYYETRLKQEHAHVICLRCGKVEEFFGEPLQRLRKQIESHFGFQVLLARTEVGGYCAHCQTLRAREVEELRVLTADAAK
PPATKSRRARTRRS
>Mature_173_residues
ALDSIEGSLKERGVRLTRQRQILLELIDTTGEHLDAERLYQMAKEKDPKLNRVTVYRTLKMLKAGGLVDELDLMHYGGDQ
HYYETRLKQEHAHVICLRCGKVEEFFGEPLQRLRKQIESHFGFQVLLARTEVGGYCAHCQTLRAREVEELRVLTADAAKP
PATKSRRARTRRS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=28.2442748091603, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 20105; Mature: 19973

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00283 SOYBEAN_KUNITZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDSIEGSLKERGVRLTRQRQILLELIDTTGEHLDAERLYQMAKEKDPKLNRVTVYRTL
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
KMLKAGGLVDELDLMHYGGDQHYYETRLKQEHAHVICLRCGKVEEFFGEPLQRLRKQIES
HHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHH
HFGFQVLLARTEVGGYCAHCQTLRAREVEELRVLTADAAKPPATKSRRARTRRS
HCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
ALDSIEGSLKERGVRLTRQRQILLELIDTTGEHLDAERLYQMAKEKDPKLNRVTVYRTL
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
KMLKAGGLVDELDLMHYGGDQHYYETRLKQEHAHVICLRCGKVEEFFGEPLQRLRKQIES
HHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHH
HFGFQVLLARTEVGGYCAHCQTLRAREVEELRVLTADAAKPPATKSRRARTRRS
HCCHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]