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The map label for this gene is steT [H]

Identifier: 116620941

GI number: 116620941

Start: 2266774

End: 2268168

Strand: Reverse

Name: steT [H]

Synonym: Acid_1822

Alternate gene names: 116620941

Gene position: 2268168-2266774 (Counterclockwise)

Preceding gene: 116620942

Following gene: 116620940

Centisome position: 22.76

GC content: 63.44

Gene sequence:

>1395_bases
ATGCCATCTCCTAAATCGCAGGACTCACGGCCCGGCTTGCTGCGGCAAATCGGGTTCTTCAGTGCCACCGCGCTGGTGAT
CTCCAACATGGTGGGTACTGGCATTTTCGCGACCACCGGTTTTATGGCGGGCGACCTGGGGAGCGCGCGGCTGATCCTGG
CGTGCTGGACCGTGGGCGCGCTGTTCGCGCTTGCGGGCGCGCTCAGCTATTCCGAGCTCGGCATCAACTTTCCCAGTTCG
GGCGGGGAGTACGTATATCTCACGCACGCCTTCGGCCCCGAATGGGGCTTCATGACCGGATGGGTCTCTTTCTTTGCCGG
CTTCTCCGCTCCCATAGCGGCGGCGGCGCTGGCCTTCTCGGATTACCTCGGTTATTTCTTCCCGTTGCTGAAACAGGCGA
ACGCATCCATCGTGATCGGCACCGGCACGCTCTCGCTGCGGCTGGGCCGGGGGCAGATGGTAGCGTCGGCGCTGATCGCC
GCGTTCACGATCCTCAACTGCCTGGGAGTGGGCCGGACTGCGAAGGTGCAAAACGTGCTCACCAGCACCAAGCTGATTGT
GATCGCGGGTTTCGTGATTTTGGGCTTCGCCGCCGGTACGGGCGACTGGCGCCATTTCTCCGAGCACGCGGTGCGGACGT
CCACCGTCAGCCTGCCGACCCAGTTCATGATCAGCCTGCTGTGGGTGATGGTCGGGTACAGCGGCTGGAATGCCGCCACA
TACGTGGCCGAGGAAGTGCGCAGGCCGGAACGGACGCTGCCGGCCGCGATCGCAGTGGGCAGCCTGATTGTCGCGGTGCT
GTACCTGGGCCTCAACCTGGTTTTTATCTACGCAACCCCGCTAGAGCAGATGAAGGGCGTGATCGCGGTCGGCACGCTCT
CGGCGTCTAACCTTTTCGGACCAGGCGTGGCCGGCGTGTTTTCCGCGCTCATGGCCGTCTCAATTGTCTCCACCGTGAAC
GCGATGGTGACGATCGGCCCGCGCGTGTATTACGCGATGGCGAAGAACCGCGCGTTCTTCAGCGCGGCGGCGCGCGTGGA
TCCGCGCTGGCACACGCCGGTCTACGCAATCCTCAGCCAGGGGCTCTGCGCCATGCTGATGACGCTGACTCCCTTCCCGC
AGCTGGTGGTGTACATCGGCTTCAGCCTCACGCTTTTCACGGTGCTCTCCGTCGCCTCCATCTTTATCTTCCGCCGGAGG
CGCCGGGACTGGCAGAGGTTACGCGCCCTGGAATTCGCGTGGCCATTGATCCCCGCATCGTATATTCTGGTTGGGACCTG
CATGATGGCTTACGGCGTGATTTGGCAACCGCGCGCGTCACTGACCGCGCTGGCCACCGTCGGCGCCGGTGCGTTGGTTT
ATCGTTTCGGAGTTCACGTGCCGAAGGTTCGATAG

Upstream 100 bases:

>100_bases
GTCCCAAGGCATTGTGGAGGCGCTGAAGAAGGTCTATCATGCACCGGACTTGCTGAAAGAACTGGGCATGCCTGTCCTAC
AATGAATCCAGGTCTCGGGA

Downstream 100 bases:

>100_bases
CGCGGAATTGAGAGAGGGTGCTCATGTTTTCGAGAAGGGACTTCGGGAGAATCGCACTGTCGGCGATTCCACTGGCAGCC
GCGCGCGGCGCAATGATCGA

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MPSPKSQDSRPGLLRQIGFFSATALVISNMVGTGIFATTGFMAGDLGSARLILACWTVGALFALAGALSYSELGINFPSS
GGEYVYLTHAFGPEWGFMTGWVSFFAGFSAPIAAAALAFSDYLGYFFPLLKQANASIVIGTGTLSLRLGRGQMVASALIA
AFTILNCLGVGRTAKVQNVLTSTKLIVIAGFVILGFAAGTGDWRHFSEHAVRTSTVSLPTQFMISLLWVMVGYSGWNAAT
YVAEEVRRPERTLPAAIAVGSLIVAVLYLGLNLVFIYATPLEQMKGVIAVGTLSASNLFGPGVAGVFSALMAVSIVSTVN
AMVTIGPRVYYAMAKNRAFFSAAARVDPRWHTPVYAILSQGLCAMLMTLTPFPQLVVYIGFSLTLFTVLSVASIFIFRRR
RRDWQRLRALEFAWPLIPASYILVGTCMMAYGVIWQPRASLTALATVGAGALVYRFGVHVPKVR

Sequences:

>Translated_464_residues
MPSPKSQDSRPGLLRQIGFFSATALVISNMVGTGIFATTGFMAGDLGSARLILACWTVGALFALAGALSYSELGINFPSS
GGEYVYLTHAFGPEWGFMTGWVSFFAGFSAPIAAAALAFSDYLGYFFPLLKQANASIVIGTGTLSLRLGRGQMVASALIA
AFTILNCLGVGRTAKVQNVLTSTKLIVIAGFVILGFAAGTGDWRHFSEHAVRTSTVSLPTQFMISLLWVMVGYSGWNAAT
YVAEEVRRPERTLPAAIAVGSLIVAVLYLGLNLVFIYATPLEQMKGVIAVGTLSASNLFGPGVAGVFSALMAVSIVSTVN
AMVTIGPRVYYAMAKNRAFFSAAARVDPRWHTPVYAILSQGLCAMLMTLTPFPQLVVYIGFSLTLFTVLSVASIFIFRRR
RRDWQRLRALEFAWPLIPASYILVGTCMMAYGVIWQPRASLTALATVGAGALVYRFGVHVPKVR
>Mature_463_residues
PSPKSQDSRPGLLRQIGFFSATALVISNMVGTGIFATTGFMAGDLGSARLILACWTVGALFALAGALSYSELGINFPSSG
GEYVYLTHAFGPEWGFMTGWVSFFAGFSAPIAAAALAFSDYLGYFFPLLKQANASIVIGTGTLSLRLGRGQMVASALIAA
FTILNCLGVGRTAKVQNVLTSTKLIVIAGFVILGFAAGTGDWRHFSEHAVRTSTVSLPTQFMISLLWVMVGYSGWNAATY
VAEEVRRPERTLPAAIAVGSLIVAVLYLGLNLVFIYATPLEQMKGVIAVGTLSASNLFGPGVAGVFSALMAVSIVSTVNA
MVTIGPRVYYAMAKNRAFFSAAARVDPRWHTPVYAILSQGLCAMLMTLTPFPQLVVYIGFSLTLFTVLSVASIFIFRRRR
RDWQRLRALEFAWPLIPASYILVGTCMMAYGVIWQPRASLTALATVGAGALVYRFGVHVPKVR

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=461, Percent_Identity=27.3318872017354, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI186910308, Length=477, Percent_Identity=26.6247379454927, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI186910306, Length=477, Percent_Identity=26.6247379454927, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI186910304, Length=477, Percent_Identity=26.6247379454927, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI115648063, Length=463, Percent_Identity=24.8380129589633, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI115648022, Length=463, Percent_Identity=24.8380129589633, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI187423910, Length=409, Percent_Identity=24.9388753056235, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI7657591, Length=409, Percent_Identity=24.9388753056235, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI7657683, Length=397, Percent_Identity=27.455919395466, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI71979932, Length=462, Percent_Identity=24.8917748917749, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI9790235, Length=464, Percent_Identity=26.2931034482759, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71999149, Length=406, Percent_Identity=23.6453201970443, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI258614003, Length=395, Percent_Identity=24.8101265822785, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI258614005, Length=395, Percent_Identity=24.8101265822785, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=24.7139588100687, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI33286430, Length=238, Percent_Identity=28.1512605042017, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI114326544, Length=395, Percent_Identity=23.0379746835443, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI114326550, Length=395, Percent_Identity=23.0379746835443, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI258645169, Length=391, Percent_Identity=24.0409207161125, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI110347453, Length=368, Percent_Identity=25.8152173913043, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87082250, Length=407, Percent_Identity=27.027027027027, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI2367353, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786908, Length=404, Percent_Identity=25.7425742574257, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=422, Percent_Identity=25.8293838862559, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71993915, Length=397, Percent_Identity=26.1964735516373, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17568033, Length=431, Percent_Identity=25.5220417633411, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193208714, Length=440, Percent_Identity=24.7727272727273, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32566695, Length=440, Percent_Identity=24.7727272727273, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982612, Length=394, Percent_Identity=23.6040609137056, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71982608, Length=394, Percent_Identity=23.6040609137056, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566699, Length=357, Percent_Identity=24.6498599439776, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71995382, Length=400, Percent_Identity=25.25, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71995388, Length=400, Percent_Identity=25.25, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71990446, Length=386, Percent_Identity=25.6476683937824, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982623, Length=288, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=415, Percent_Identity=24.578313253012, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321492, Length=281, Percent_Identity=28.4697508896797, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321751, Length=429, Percent_Identity=25.8741258741259, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI221331183, Length=466, Percent_Identity=27.6824034334764, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17647653, Length=466, Percent_Identity=27.6824034334764, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24664379, Length=466, Percent_Identity=27.6824034334764, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24651635, Length=372, Percent_Identity=27.1505376344086, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24651633, Length=372, Percent_Identity=27.1505376344086, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI45550968, Length=423, Percent_Identity=26.4775413711584, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19921172, Length=423, Percent_Identity=26.4775413711584, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI21357367, Length=467, Percent_Identity=24.4111349036403, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641995, Length=410, Percent_Identity=25.8536585365854, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641993, Length=410, Percent_Identity=25.8536585365854, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24667468, Length=414, Percent_Identity=24.1545893719807, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49694; Mature: 49563

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPKSQDSRPGLLRQIGFFSATALVISNMVGTGIFATTGFMAGDLGSARLILACWTVGA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHCCCCCHHHHHHHHHHHH
LFALAGALSYSELGINFPSSGGEYVYLTHAFGPEWGFMTGWVSFFAGFSAPIAAAALAFS
HHHHHHHCCHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
DYLGYFFPLLKQANASIVIGTGTLSLRLGRGQMVASALIAAFTILNCLGVGRTAKVQNVL
HHHHHHHHHHHCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TSTKLIVIAGFVILGFAAGTGDWRHFSEHAVRTSTVSLPTQFMISLLWVMVGYSGWNAAT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHH
YVAEEVRRPERTLPAAIAVGSLIVAVLYLGLNLVFIYATPLEQMKGVIAVGTLSASNLFG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCEEEEEEECCCCCCC
PGVAGVFSALMAVSIVSTVNAMVTIGPRVYYAMAKNRAFFSAAARVDPRWHTPVYAILSQ
CCHHHHHHHHHHHHHHHHHHHHEEECCHHEEHHHHCCHHHHHHHCCCCCCCCHHHHHHHH
GLCAMLMTLTPFPQLVVYIGFSLTLFTVLSVASIFIFRRRRRDWQRLRALEFAWPLIPAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YILVGTCMMAYGVIWQPRASLTALATVGAGALVYRFGVHVPKVR
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSPKSQDSRPGLLRQIGFFSATALVISNMVGTGIFATTGFMAGDLGSARLILACWTVGA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHCCCCCHHHHHHHHHHHH
LFALAGALSYSELGINFPSSGGEYVYLTHAFGPEWGFMTGWVSFFAGFSAPIAAAALAFS
HHHHHHHCCHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
DYLGYFFPLLKQANASIVIGTGTLSLRLGRGQMVASALIAAFTILNCLGVGRTAKVQNVL
HHHHHHHHHHHCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TSTKLIVIAGFVILGFAAGTGDWRHFSEHAVRTSTVSLPTQFMISLLWVMVGYSGWNAAT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHH
YVAEEVRRPERTLPAAIAVGSLIVAVLYLGLNLVFIYATPLEQMKGVIAVGTLSASNLFG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHCCCEEEEEEECCCCCCC
PGVAGVFSALMAVSIVSTVNAMVTIGPRVYYAMAKNRAFFSAAARVDPRWHTPVYAILSQ
CCHHHHHHHHHHHHHHHHHHHHEEECCHHEEHHHHCCHHHHHHHCCCCCCCCHHHHHHHH
GLCAMLMTLTPFPQLVVYIGFSLTLFTVLSVASIFIFRRRRRDWQRLRALEFAWPLIPAS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YILVGTCMMAYGVIWQPRASLTALATVGAGALVYRFGVHVPKVR
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]