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The map label for this gene is macB [H]

Identifier: 116620843

GI number: 116620843

Start: 2137885

End: 2139147

Strand: Reverse

Name: macB [H]

Synonym: Acid_1724

Alternate gene names: 116620843

Gene position: 2139147-2137885 (Counterclockwise)

Preceding gene: 116620844

Following gene: 116620842

Centisome position: 21.47

GC content: 61.92

Gene sequence:

>1263_bases
ATGCTGCACGCATATCGTCAACATGTTCGCGAGAATCTGCTGCTGGCGATGGATACGCTGCGAACGCACAAGTTCCGCTC
GTTCCTCACGGTGCTCGGCGTCCTGATCGGCACTACCACGGTGATCGCGGTGACTTCGATCATCGCGGGATTGGACAAGC
AGCTGGTGGATGTGGCGGAGCAGTTTGGCACGCGGACGCTGTGGGTGTACAAGCTGCAGATGGGCGCGCCGCACGCTATG
ACACGGGAAGAGCGGCTGCGCAAGCCGCTGACGTATGAAGACGCGATGGCGATCAAGGAGCAATCGCCCTCCACGTCCAC
GGTTTCGGTGGAGCTGTTCCGCGAGTTGGGAGAGTTCGGGCTGCCGCCGGTCACGGCACGGTACAAAGGGCAGAACATGC
TGGATGCGCTGTTCGTGGGCGTGACGGCGGACCACTTGCGGCTGATCAATGCGACGCTCGGCCAAGGCCGTTTTTTCACG
GAGACGGAGGACCTGCACCGGCGCGATGTGGCGGTGATCGGCAACGGGATACGCGAGCGGTTTTTCACGCACGAAGATCC
GATCGGCAAGAGCATTCTCGTGGATGGCCACCAGTTGGAGATCATCGGCACGCTGACAAAGTTCAAATCGTTCCTGGGGG
ACGACCAGAATGACAAGGCGGTGCTGATTCCCTACCAATCATTTAAGAAGGCCTACCCGGAGGCCAAGGACCATTTCATT
TGCGTTCTTGTGGAACCGGGGAAAATGGATCAGGCGCGCGATGAGGTCACCGAGCTGTTGCGGCGGCGACGGCACGTGAA
GCCGTCGGAGCCGGACAACTTCGGCGTCTCAAGCGCGGAGCTAGTGATCGGCCAGTTCCGCCAGCTGATCGCCACGGTCG
GGCTGGTGATGGTGGTGATTTCATCGATCGGGCTGCTGGTGGGGGGTATCGGGGTGATGAATATCATGCTGGTTTCGGTG
ACGGAGCGGACGCGGGAGATCGGCGTGCGGAAGGCGATTGGGGCGCGGCGCAGCGACATCGTGTGGCAGTTTCTGCTGGA
GGCGATGACGCTGACAGCGTTCGGTGGTCTGGTGGGCATCCTGGTGGGCTGGCTGCTCTCGGTGGCGATCCGGACGTTCG
TGCCGACACTGCCTTCGACGGTGCCGGTGTGGAGCGTGGTGGCTGGCTTCAGCGTCGCGACCAGTGTCGGGTTGTTCTTC
GGGCTTTGGCCGGCACTGAAAGCGGCGCGACTGGACCCGATTGCGGCCTTACGGCACGAATGA

Upstream 100 bases:

>100_bases
GAGTCGGGCTTTCGGCCGCGGTGGGACTGTTCTTCGGAATCTACCCCGCGCGCAAGGCGGCAAGGCTGGATCCCATCGAG
GCGCTCCGGTCGGAGAATTG

Downstream 100 bases:

>100_bases
ATGAGTTGAGTTGCCGCAGGGGGTGAGGTTGCGCTATGCTGGAATCTCGATCACTCTGTAAGGATTAGATTTAGCAAAGA
TGGCGAATACTTATTCCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MLHAYRQHVRENLLLAMDTLRTHKFRSFLTVLGVLIGTTTVIAVTSIIAGLDKQLVDVAEQFGTRTLWVYKLQMGAPHAM
TREERLRKPLTYEDAMAIKEQSPSTSTVSVELFRELGEFGLPPVTARYKGQNMLDALFVGVTADHLRLINATLGQGRFFT
ETEDLHRRDVAVIGNGIRERFFTHEDPIGKSILVDGHQLEIIGTLTKFKSFLGDDQNDKAVLIPYQSFKKAYPEAKDHFI
CVLVEPGKMDQARDEVTELLRRRRHVKPSEPDNFGVSSAELVIGQFRQLIATVGLVMVVISSIGLLVGGIGVMNIMLVSV
TERTREIGVRKAIGARRSDIVWQFLLEAMTLTAFGGLVGILVGWLLSVAIRTFVPTLPSTVPVWSVVAGFSVATSVGLFF
GLWPALKAARLDPIAALRHE

Sequences:

>Translated_420_residues
MLHAYRQHVRENLLLAMDTLRTHKFRSFLTVLGVLIGTTTVIAVTSIIAGLDKQLVDVAEQFGTRTLWVYKLQMGAPHAM
TREERLRKPLTYEDAMAIKEQSPSTSTVSVELFRELGEFGLPPVTARYKGQNMLDALFVGVTADHLRLINATLGQGRFFT
ETEDLHRRDVAVIGNGIRERFFTHEDPIGKSILVDGHQLEIIGTLTKFKSFLGDDQNDKAVLIPYQSFKKAYPEAKDHFI
CVLVEPGKMDQARDEVTELLRRRRHVKPSEPDNFGVSSAELVIGQFRQLIATVGLVMVVISSIGLLVGGIGVMNIMLVSV
TERTREIGVRKAIGARRSDIVWQFLLEAMTLTAFGGLVGILVGWLLSVAIRTFVPTLPSTVPVWSVVAGFSVATSVGLFF
GLWPALKAARLDPIAALRHE
>Mature_420_residues
MLHAYRQHVRENLLLAMDTLRTHKFRSFLTVLGVLIGTTTVIAVTSIIAGLDKQLVDVAEQFGTRTLWVYKLQMGAPHAM
TREERLRKPLTYEDAMAIKEQSPSTSTVSVELFRELGEFGLPPVTARYKGQNMLDALFVGVTADHLRLINATLGQGRFFT
ETEDLHRRDVAVIGNGIRERFFTHEDPIGKSILVDGHQLEIIGTLTKFKSFLGDDQNDKAVLIPYQSFKKAYPEAKDHFI
CVLVEPGKMDQARDEVTELLRRRRHVKPSEPDNFGVSSAELVIGQFRQLIATVGLVMVVISSIGLLVGGIGVMNIMLVSV
TERTREIGVRKAIGARRSDIVWQFLLEAMTLTAFGGLVGILVGWLLSVAIRTFVPTLPSTVPVWSVVAGFSVATSVGLFF
GLWPALKAARLDPIAALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=428, Percent_Identity=30.607476635514, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46558; Mature: 46558

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHAYRQHVRENLLLAMDTLRTHKFRSFLTVLGVLIGTTTVIAVTSIIAGLDKQLVDVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFGTRTLWVYKLQMGAPHAMTREERLRKPLTYEDAMAIKEQSPSTSTVSVELFRELGEFG
HHCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
LPPVTARYKGQNMLDALFVGVTADHLRLINATLGQGRFFTETEDLHRRDVAVIGNGIRER
CCCCEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHH
FFTHEDPIGKSILVDGHQLEIIGTLTKFKSFLGDDQNDKAVLIPYQSFKKAYPEAKDHFI
HCCCCCCCCCEEEECCCEEEEHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCCCCEE
CVLVEPGKMDQARDEVTELLRRRRHVKPSEPDNFGVSSAELVIGQFRQLIATVGLVMVVI
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SSIGLLVGGIGVMNIMLVSVTERTREIGVRKAIGARRSDIVWQFLLEAMTLTAFGGLVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGWLLSVAIRTFVPTLPSTVPVWSVVAGFSVATSVGLFFGLWPALKAARLDPIAALRHE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MLHAYRQHVRENLLLAMDTLRTHKFRSFLTVLGVLIGTTTVIAVTSIIAGLDKQLVDVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFGTRTLWVYKLQMGAPHAMTREERLRKPLTYEDAMAIKEQSPSTSTVSVELFRELGEFG
HHCCCEEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
LPPVTARYKGQNMLDALFVGVTADHLRLINATLGQGRFFTETEDLHRRDVAVIGNGIRER
CCCCEECCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHH
FFTHEDPIGKSILVDGHQLEIIGTLTKFKSFLGDDQNDKAVLIPYQSFKKAYPEAKDHFI
HCCCCCCCCCEEEECCCEEEEHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCCCCEE
CVLVEPGKMDQARDEVTELLRRRRHVKPSEPDNFGVSSAELVIGQFRQLIATVGLVMVVI
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SSIGLLVGGIGVMNIMLVSVTERTREIGVRKAIGARRSDIVWQFLLEAMTLTAFGGLVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVGWLLSVAIRTFVPTLPSTVPVWSVVAGFSVATSVGLFFGLWPALKAARLDPIAALRHE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA