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The map label for this gene is macB [H]

Identifier: 116620844

GI number: 116620844

Start: 2139147

End: 2140421

Strand: Reverse

Name: macB [H]

Synonym: Acid_1725

Alternate gene names: 116620844

Gene position: 2140421-2139147 (Counterclockwise)

Preceding gene: 116620845

Following gene: 116620843

Centisome position: 21.48

GC content: 60.78

Gene sequence:

>1275_bases
ATGGGTGATAAGTTCGGTGCGATGAAGACCGGTCGCGGCATTTCTCCGTGGACCACCGGCCGCGAGGCCTTTTGGATCGC
GGTTGAGGCGCTGCGCAGCCACAAGCTGCGCTCTTTTCTGACGCTGCTTGGGGTGGTGATCGCGACCACCACGCTGATCG
TGGTCATGTCGATTGTGAACGGCATGAACCTCTACATCGCGGAGCACATCGCCAACCTGGGCACGAATACTTTCGTGCTG
CACCAGTTCCAGTGGGCGCAGGGTTTCGATTCCTTCCTCAACGCGCGGCGGCGAAATAAACCGATTCGCATTGAGGACTA
CGAATATCTGCGGGATAACCTGCAAGGGTACCGGCAAATCGGGGCGATGGCCAGCCTCAATCCCAGTCCGGCTGCGCGCT
ACAAGGGCCGGCTGATCGACGAGATCACGTTGAACGGGATGACGGCGAGCTTCGCGGATATCGGCCGGGAGAAAGTAGAG
CAGGGGCGGTACATCAGCGAGCAGGATTACCAGCACAATGCACGGGTCTGCGTGATCGGCGCGGACCTGGTGGACAAGCT
CTTTCCCAACAGCGACCCGCTGGACAAGGAAATTCAAATCGGTGGTCTGCCGTTCCGCGTGGTGGGCGTCACGGAGCGGG
TGGGCAGTACATTCGGGCAGAGCCAGGATAATTTCGCGATCGTACCGCTGAGCACGTTCAAAGCGATCTGGATGGGGCGT
CCGGAACTGCTGGTGTACATCAAGTCGCCGGATGGCCCGCACATGGCGGAGTTGCAGGATGAAGTGCGCGCGCTGATGCG
GATGCGCCGTCACGTTCCCTATCGCGAGGAGGACACGTTTGGGATCAATGCGTCGGACACGCTGATGAGCGCGTGGAAGA
ATTTGACGGGGACGATCTTCGCGGTAACGATCGGCCTGGTGGCGGTGTTCATGGTGGTGGGCGGAATCGTGATCATGAAT
ATCATGCTTGCGAGCGTGACGGAGCGCACGCACGAGATCGGCGTGCGCAAATCGCTGGGAGCGCGGCGGCGCGATATTCT
CTGGCAGTTCGTGTTTGAATCCGGGATGATGTCGAGTATCGGCGGGCTGGCGGGAGTACTGGCCGCGGTAGCGGTGGCGC
GCGTAGTCAACATTTATTTCACGGCGGATATTCCGGTGGCGGCGGTGATGGTGGGAGTCGGGCTTTCGGCCGCGGTGGGA
CTGTTCTTCGGAATCTACCCCGCGCGCAAGGCGGCAAGGCTGGATCCCATCGAGGCGCTCCGGTCGGAGAATTGA

Upstream 100 bases:

>100_bases
ACGATCGACTTCAAATTCGGGCCTCCGAAGGCAGCTGCGCCCGCTCCGCCGAGGATTCCAGGCGCGGTAGTGCTGATGCA
GGTGGTTGCCTGAATCCGGT

Downstream 100 bases:

>100_bases
TGCTGCACGCATATCGTCAACATGTTCGCGAGAATCTGCTGCTGGCGATGGATACGCTGCGAACGCACAAGTTCCGCTCG
TTCCTCACGGTGCTCGGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MGDKFGAMKTGRGISPWTTGREAFWIAVEALRSHKLRSFLTLLGVVIATTTLIVVMSIVNGMNLYIAEHIANLGTNTFVL
HQFQWAQGFDSFLNARRRNKPIRIEDYEYLRDNLQGYRQIGAMASLNPSPAARYKGRLIDEITLNGMTASFADIGREKVE
QGRYISEQDYQHNARVCVIGADLVDKLFPNSDPLDKEIQIGGLPFRVVGVTERVGSTFGQSQDNFAIVPLSTFKAIWMGR
PELLVYIKSPDGPHMAELQDEVRALMRMRRHVPYREEDTFGINASDTLMSAWKNLTGTIFAVTIGLVAVFMVVGGIVIMN
IMLASVTERTHEIGVRKSLGARRRDILWQFVFESGMMSSIGGLAGVLAAVAVARVVNIYFTADIPVAAVMVGVGLSAAVG
LFFGIYPARKAARLDPIEALRSEN

Sequences:

>Translated_424_residues
MGDKFGAMKTGRGISPWTTGREAFWIAVEALRSHKLRSFLTLLGVVIATTTLIVVMSIVNGMNLYIAEHIANLGTNTFVL
HQFQWAQGFDSFLNARRRNKPIRIEDYEYLRDNLQGYRQIGAMASLNPSPAARYKGRLIDEITLNGMTASFADIGREKVE
QGRYISEQDYQHNARVCVIGADLVDKLFPNSDPLDKEIQIGGLPFRVVGVTERVGSTFGQSQDNFAIVPLSTFKAIWMGR
PELLVYIKSPDGPHMAELQDEVRALMRMRRHVPYREEDTFGINASDTLMSAWKNLTGTIFAVTIGLVAVFMVVGGIVIMN
IMLASVTERTHEIGVRKSLGARRRDILWQFVFESGMMSSIGGLAGVLAAVAVARVVNIYFTADIPVAAVMVGVGLSAAVG
LFFGIYPARKAARLDPIEALRSEN
>Mature_423_residues
GDKFGAMKTGRGISPWTTGREAFWIAVEALRSHKLRSFLTLLGVVIATTTLIVVMSIVNGMNLYIAEHIANLGTNTFVLH
QFQWAQGFDSFLNARRRNKPIRIEDYEYLRDNLQGYRQIGAMASLNPSPAARYKGRLIDEITLNGMTASFADIGREKVEQ
GRYISEQDYQHNARVCVIGADLVDKLFPNSDPLDKEIQIGGLPFRVVGVTERVGSTFGQSQDNFAIVPLSTFKAIWMGRP
ELLVYIKSPDGPHMAELQDEVRALMRMRRHVPYREEDTFGINASDTLMSAWKNLTGTIFAVTIGLVAVFMVVGGIVIMNI
MLASVTERTHEIGVRKSLGARRRDILWQFVFESGMMSSIGGLAGVLAAVAVARVVNIYFTADIPVAAVMVGVGLSAAVGL
FFGIYPARKAARLDPIEALRSEN

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=419, Percent_Identity=29.5942720763723, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46824; Mature: 46693

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDKFGAMKTGRGISPWTTGREAFWIAVEALRSHKLRSFLTLLGVVIATTTLIVVMSIVN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMNLYIAEHIANLGTNTFVLHQFQWAQGFDSFLNARRRNKPIRIEDYEYLRDNLQGYRQI
CCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHH
GAMASLNPSPAARYKGRLIDEITLNGMTASFADIGREKVEQGRYISEQDYQHNARVCVIG
HHHHCCCCCCHHHHCCCHHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
ADLVDKLFPNSDPLDKEIQIGGLPFRVVGVTERVGSTFGQSQDNFAIVPLSTFKAIWMGR
HHHHHHHCCCCCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCC
PELLVYIKSPDGPHMAELQDEVRALMRMRRHVPYREEDTFGINASDTLMSAWKNLTGTIF
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHH
AVTIGLVAVFMVVGGIVIMNIMLASVTERTHEIGVRKSLGARRRDILWQFVFESGMMSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
GGLAGVLAAVAVARVVNIYFTADIPVAAVMVGVGLSAAVGLFFGIYPARKAARLDPIEAL
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RSEN
HCCC
>Mature Secondary Structure 
GDKFGAMKTGRGISPWTTGREAFWIAVEALRSHKLRSFLTLLGVVIATTTLIVVMSIVN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMNLYIAEHIANLGTNTFVLHQFQWAQGFDSFLNARRRNKPIRIEDYEYLRDNLQGYRQI
CCHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHH
GAMASLNPSPAARYKGRLIDEITLNGMTASFADIGREKVEQGRYISEQDYQHNARVCVIG
HHHHCCCCCCHHHHCCCHHHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
ADLVDKLFPNSDPLDKEIQIGGLPFRVVGVTERVGSTFGQSQDNFAIVPLSTFKAIWMGR
HHHHHHHCCCCCCCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCEEEEEHHHHHHHHCCC
PELLVYIKSPDGPHMAELQDEVRALMRMRRHVPYREEDTFGINASDTLMSAWKNLTGTIF
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHH
AVTIGLVAVFMVVGGIVIMNIMLASVTERTHEIGVRKSLGARRRDILWQFVFESGMMSSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHH
GGLAGVLAAVAVARVVNIYFTADIPVAAVMVGVGLSAAVGLFFGIYPARKAARLDPIEAL
HHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHH
RSEN
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA