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The map label for this gene is cocE [H]

Identifier: 116620702

GI number: 116620702

Start: 1941128

End: 1943092

Strand: Direct

Name: cocE [H]

Synonym: Acid_1582

Alternate gene names: 116620702

Gene position: 1941128-1943092 (Clockwise)

Preceding gene: 116620695

Following gene: 116620707

Centisome position: 19.48

GC content: 60.56

Gene sequence:

>1965_bases
ATGAAGTTTCACCCACTCTGTAAGAGCCGGCTGTTAAAGGGCGGCGTGTCGCTCCTGCTGATCGGCGGCTTCGCAGCCAG
CGTCGCGCAACAGCGGCCCGCACCGAATCCGCAAATGATCGCGGCGCGCAACGCCAGCGAGAAGGAACTCGAAGATCTGG
CGATTATCGATCGCAAGCTGATGGTTCCGATGCGCGATGGCAAACGCATGGCGACCGACGTTTATCGTCCCAAGGACACT
TCGAAGAAGTATCCGATCATTTTCGTGCGGACTCCTTACAACTTCAACTTTTGGGATGTCCGCAACGGAGCGCCGCGCGA
CATGAGCGCGGAGGTGGCGGCGGTCAAGCGCGGGTACGCGTACGTCGAGATGAACGAGCGCGGCCACTTCTTTTCGGAGG
GGACTTACGACATTCTCGGCGCACCGCTGACGGATGGCACCGATGCGATCACGTGGATGTCGTCGCAGCCGTGGTCCAAC
GGCAAGGTCGGGACGATCGGCTGCTCGTCCACGGCGGAGTGGCAGATGGGCGTGGCGGCGCAGGGCAATCCGGCGTTCGC
GGCCATGATCCCGCAGGGTTTCGGCGCGGGTGTCGGCAGGGTTGCGCCGTACTTCGAGCAGGGCAACTGGTATCGCGGGG
GCGCGGTGCAAATGCTGTTCATCGCGTGGCTGTATGGAGAGCAGAACCAGGTGCGGCCGATGTTCCCGCCCAACACCTCG
CAGGCGGATTTGATCAAAGCGTCGAAGCTATTCGACCTGGCGCCGCAGATGCCGCCGGTGGATTGGTCGAAGGCGCTGCA
AATGCTTCCGGTCGCGGACATCATGAAGAAGGTGGATGGTCCCGCGGGAATTTTCGCGGACCGCGCGGAAGTTTCCACCG
GCGGCGCGATGATCAAACGAACACCCAACGATCCGGCGTGGTATCGCGGCGGATTGTGGCACGACGATATGAAGATCAAC
GTGCCCGGCTTCTGGTTCATGTCCTGGTACGACGTTTCGGTGGGGCCGAACCTCGCCGCCTATAATTACGTGCGCGCCAC
TGCCAAGCCGGAGATCGGCAAGCAGCAGTACGCCGTGATTGCTCCGACGCTGCATTGCTCTTACAAGCGAGCGACCGAGC
ACACGATGGTGGGCGAGCGCGATATGGGCGATGCCCGCCTGGACTACGACGAGCTGACTTACGGCTGGTTCGATCACTTC
CTTAAGGGCGAAGATAACAAGGTGCTGGAAACGATGCCGCGCGTTCGTTACTACACGATGGGGATGAACAAGTGGCAATC
CTCGGAGACCTGGCCGCCGGCGGGAGCGCGGCCGATGAAGCTCTTCCTGGGGAGCGCCGGAAAGGCGAATACGGGCAAGG
GTGACGGGGCTCTCGCGACTGCGGTGCCCTCTGCCGACAGCCCCGATTCGTTTACGTACGATCCGATGAATCCCGTGCCC
TCGTACGGCGGAAACGTCTGCTGCACGGGGAACGCGGTGCAAGGCGGCGCTTTCGATCAGCGCAAGATGGAAGAGCGGCC
GGACATTCTGGTGTACACGTCGGACCCTTTGAAAGAGGGCATTGAAGCCAGTGGTCCGATCCAAGCGACGCTTTATGTAT
CGTCCGACGCGAAGGACACGGATATTACGGTCAAGTTGATCGACGTGCTTCCCGACGGCACGGCGTACAACCTGGATGAG
ACGATCCAGCGCCTGCGGTATCGCGAGGGCTATGACAAACCGCCGGTGTGGATGGAGAACGGCAAGGTGTACAAAGTGAC
GCTGCAGCCGATGAATACGAGTAACTTCTTCGCGGTTGGACACCGCATTCGGATTGAAGTATCGAGCAGCAATTTTCCGC
GCTTCGACCGGAATTTGAATACCGGCGGGAATAACTACGATGAGGCGAAGGGGGTGGTGGCGCATACCGTGATCCATCAC
TCGGCAACTTATCCGTCACAGGTGACGTTGACGGTGGTGAAGTAG

Upstream 100 bases:

>100_bases
TCGCCAGAACACTTCACGTTTCACCTGCGCTGTGTTCGTGTACTCGCAATCGGAGCACGTGAAAACGGTACACTGGCTAT
TTCCCGAGGAGACCTGCGAA

Downstream 100 bases:

>100_bases
GTGCGTCTCCGCGGAAGCCGCCTGAAAGGCAGCTGCAGCCAGGATTGGCTGCCCCACAAGTCGGCAAGCAACGGACGCTC
CCTTACTTACGGTCGCGGCT

Product: X-Pro dipeptidyl-peptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MKFHPLCKSRLLKGGVSLLLIGGFAASVAQQRPAPNPQMIAARNASEKELEDLAIIDRKLMVPMRDGKRMATDVYRPKDT
SKKYPIIFVRTPYNFNFWDVRNGAPRDMSAEVAAVKRGYAYVEMNERGHFFSEGTYDILGAPLTDGTDAITWMSSQPWSN
GKVGTIGCSSTAEWQMGVAAQGNPAFAAMIPQGFGAGVGRVAPYFEQGNWYRGGAVQMLFIAWLYGEQNQVRPMFPPNTS
QADLIKASKLFDLAPQMPPVDWSKALQMLPVADIMKKVDGPAGIFADRAEVSTGGAMIKRTPNDPAWYRGGLWHDDMKIN
VPGFWFMSWYDVSVGPNLAAYNYVRATAKPEIGKQQYAVIAPTLHCSYKRATEHTMVGERDMGDARLDYDELTYGWFDHF
LKGEDNKVLETMPRVRYYTMGMNKWQSSETWPPAGARPMKLFLGSAGKANTGKGDGALATAVPSADSPDSFTYDPMNPVP
SYGGNVCCTGNAVQGGAFDQRKMEERPDILVYTSDPLKEGIEASGPIQATLYVSSDAKDTDITVKLIDVLPDGTAYNLDE
TIQRLRYREGYDKPPVWMENGKVYKVTLQPMNTSNFFAVGHRIRIEVSSSNFPRFDRNLNTGGNNYDEAKGVVAHTVIHH
SATYPSQVTLTVVK

Sequences:

>Translated_654_residues
MKFHPLCKSRLLKGGVSLLLIGGFAASVAQQRPAPNPQMIAARNASEKELEDLAIIDRKLMVPMRDGKRMATDVYRPKDT
SKKYPIIFVRTPYNFNFWDVRNGAPRDMSAEVAAVKRGYAYVEMNERGHFFSEGTYDILGAPLTDGTDAITWMSSQPWSN
GKVGTIGCSSTAEWQMGVAAQGNPAFAAMIPQGFGAGVGRVAPYFEQGNWYRGGAVQMLFIAWLYGEQNQVRPMFPPNTS
QADLIKASKLFDLAPQMPPVDWSKALQMLPVADIMKKVDGPAGIFADRAEVSTGGAMIKRTPNDPAWYRGGLWHDDMKIN
VPGFWFMSWYDVSVGPNLAAYNYVRATAKPEIGKQQYAVIAPTLHCSYKRATEHTMVGERDMGDARLDYDELTYGWFDHF
LKGEDNKVLETMPRVRYYTMGMNKWQSSETWPPAGARPMKLFLGSAGKANTGKGDGALATAVPSADSPDSFTYDPMNPVP
SYGGNVCCTGNAVQGGAFDQRKMEERPDILVYTSDPLKEGIEASGPIQATLYVSSDAKDTDITVKLIDVLPDGTAYNLDE
TIQRLRYREGYDKPPVWMENGKVYKVTLQPMNTSNFFAVGHRIRIEVSSSNFPRFDRNLNTGGNNYDEAKGVVAHTVIHH
SATYPSQVTLTVVK
>Mature_654_residues
MKFHPLCKSRLLKGGVSLLLIGGFAASVAQQRPAPNPQMIAARNASEKELEDLAIIDRKLMVPMRDGKRMATDVYRPKDT
SKKYPIIFVRTPYNFNFWDVRNGAPRDMSAEVAAVKRGYAYVEMNERGHFFSEGTYDILGAPLTDGTDAITWMSSQPWSN
GKVGTIGCSSTAEWQMGVAAQGNPAFAAMIPQGFGAGVGRVAPYFEQGNWYRGGAVQMLFIAWLYGEQNQVRPMFPPNTS
QADLIKASKLFDLAPQMPPVDWSKALQMLPVADIMKKVDGPAGIFADRAEVSTGGAMIKRTPNDPAWYRGGLWHDDMKIN
VPGFWFMSWYDVSVGPNLAAYNYVRATAKPEIGKQQYAVIAPTLHCSYKRATEHTMVGERDMGDARLDYDELTYGWFDHF
LKGEDNKVLETMPRVRYYTMGMNKWQSSETWPPAGARPMKLFLGSAGKANTGKGDGALATAVPSADSPDSFTYDPMNPVP
SYGGNVCCTGNAVQGGAFDQRKMEERPDILVYTSDPLKEGIEASGPIQATLYVSSDAKDTDITVKLIDVLPDGTAYNLDE
TIQRLRYREGYDKPPVWMENGKVYKVTLQPMNTSNFFAVGHRIRIEVSSSNFPRFDRNLNTGGNNYDEAKGVVAHTVIHH
SATYPSQVTLTVVK

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 72373; Mature: 72373

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFHPLCKSRLLKGGVSLLLIGGFAASVAQQRPAPNPQMIAARNASEKELEDLAIIDRKL
CCCCHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHEE
MVPMRDGKRMATDVYRPKDTSKKYPIIFVRTPYNFNFWDVRNGAPRDMSAEVAAVKRGYA
EEECCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHCCEE
YVEMNERGHFFSEGTYDILGAPLTDGTDAITWMSSQPWSNGKVGTIGCSSTAEWQMGVAA
EEEECCCCCEECCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEEEEE
QGNPAFAAMIPQGFGAGVGRVAPYFEQGNWYRGGAVQMLFIAWLYGEQNQVRPMFPPNTS
CCCCEEEEECCCCCCCCHHHCCCHHHCCCEECCCHHEEEEEEEHCCCCCCCCCCCCCCCC
QADLIKASKLFDLAPQMPPVDWSKALQMLPVADIMKKVDGPAGIFADRAEVSTGGAMIKR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCCCEEEEE
TPNDPAWYRGGLWHDDMKINVPGFWFMSWYDVSVGPNLAAYNYVRATAKPEIGKQQYAVI
CCCCCCCCCCCEEECCCEEECCEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEE
APTLHCSYKRATEHTMVGERDMGDARLDYDELTYGWFDHFLKGEDNKVLETMPRVRYYTM
ECEEECCCHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEE
GMNKWQSSETWPPAGARPMKLFLGSAGKANTGKGDGALATAVPSADSPDSFTYDPMNPVP
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEECCCCCCCC
SYGGNVCCTGNAVQGGAFDQRKMEERPDILVYTSDPLKEGIEASGPIQATLYVSSDAKDT
CCCCCEEEECCCCCCCCCCHHHHHCCCCEEEEECCHHHHCCCCCCCEEEEEEEECCCCCC
DITVKLIDVLPDGTAYNLDETIQRLRYREGYDKPPVWMENGKVYKVTLQPMNTSNFFAVG
CEEEEEEEECCCCCEECHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEEECCCCCEEEEC
HRIRIEVSSSNFPRFDRNLNTGGNNYDEAKGVVAHTVIHHSATYPSQVTLTVVK
EEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKFHPLCKSRLLKGGVSLLLIGGFAASVAQQRPAPNPQMIAARNASEKELEDLAIIDRKL
CCCCHHHHHHHHHCCCEEEEECCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHEE
MVPMRDGKRMATDVYRPKDTSKKYPIIFVRTPYNFNFWDVRNGAPRDMSAEVAAVKRGYA
EEECCCCCCHHHHCCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHCCEE
YVEMNERGHFFSEGTYDILGAPLTDGTDAITWMSSQPWSNGKVGTIGCSSTAEWQMGVAA
EEEECCCCCEECCCCCEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCEEEEEEE
QGNPAFAAMIPQGFGAGVGRVAPYFEQGNWYRGGAVQMLFIAWLYGEQNQVRPMFPPNTS
CCCCEEEEECCCCCCCCHHHCCCHHHCCCEECCCHHEEEEEEEHCCCCCCCCCCCCCCCC
QADLIKASKLFDLAPQMPPVDWSKALQMLPVADIMKKVDGPAGIFADRAEVSTGGAMIKR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCEEECCCCCCCCCEEEEE
TPNDPAWYRGGLWHDDMKINVPGFWFMSWYDVSVGPNLAAYNYVRATAKPEIGKQQYAVI
CCCCCCCCCCCEEECCCEEECCEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEE
APTLHCSYKRATEHTMVGERDMGDARLDYDELTYGWFDHFLKGEDNKVLETMPRVRYYTM
ECEEECCCHHCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEEE
GMNKWQSSETWPPAGARPMKLFLGSAGKANTGKGDGALATAVPSADSPDSFTYDPMNPVP
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEECCCCCCCC
SYGGNVCCTGNAVQGGAFDQRKMEERPDILVYTSDPLKEGIEASGPIQATLYVSSDAKDT
CCCCCEEEECCCCCCCCCCHHHHHCCCCEEEEECCHHHHCCCCCCCEEEEEEEECCCCCC
DITVKLIDVLPDGTAYNLDETIQRLRYREGYDKPPVWMENGKVYKVTLQPMNTSNFFAVG
CEEEEEEEECCCCCEECHHHHHHHHHHHCCCCCCCEEEECCEEEEEEEEECCCCCEEEEC
HRIRIEVSSSNFPRFDRNLNTGGNNYDEAKGVVAHTVIHHSATYPSQVTLTVVK
EEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]