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The map label for this gene is dapE [H]

Identifier: 116620614

GI number: 116620614

Start: 1831393

End: 1832787

Strand: Direct

Name: dapE [H]

Synonym: Acid_1493

Alternate gene names: 116620614

Gene position: 1831393-1832787 (Clockwise)

Preceding gene: 116620613

Following gene: 116620617

Centisome position: 18.38

GC content: 65.09

Gene sequence:

>1395_bases
ATGAAATTGATGGCGTGTTTGGCGATGCTGGCCGCCGGCGGGTTGGCGCAAGAGCGGTATCCGGTGGACTGGCGCAAGCT
GGAGCCGGAGGTCCTTGCCAACTTCACGGCGCTGCTGAAGATCGATACGAGCAATCCGCCGGGCAATGAGACGGCGGCGG
CGAAGGCGATCCAGGGGGTGCTGGAGCGCGAAGGGATTCCGTGCAAGCTGTTCGCCGTGGATCCGGCGCGCGCGAACCTG
GTGGCGCGCATCAAGGGGACGGGCGCAAAGAAGCCGCTCTTGATCATGGGCCACACGGATGTGGTCGGGGTGCAGCGCGA
GAAGTGGAGCTTCGACCCATTCGCGGCGATCAACCGGAACGGCGTGATCTATGCGCGGGGTTCGCGCGACGATAAGCCGC
ACGTGGTGGCAGGAATCATGACGCTGCTGCTGTTGAAGCGGATGAAGGTGAAACTGGATCGCGATGTCATCTTCCTGGCG
GAGGCGGGGGAAGAGGGTACTACCACATTCGGCATCGATTACATGGTGAAGGAGCACTGGCCGGAGATCGAGGCGGAGTT
CGCGATGGCGGAAGGCGGATCGATCGTGGAGCAGGGCGGAAAGCCGCACCACGTGTTGATCAGCACGACGGAGAAATCAC
CGCAGCGAGTGCGGCTGGTGGCGCACGGTCCGGCGGGGCATGCGTCGCGGCCGGAGATGACGAACGCGGTGGTGCACCTG
GCGGAGGCGGTGGCGAAGGCAGGGAACTGGCAGACGCCGATGCGGCTGAACGAGACCACGCGCGTGTATTTCCAGCGGCT
GGCGGAGATCTCGGCGCCGGAGGCGGCGGCGCGGTATCGCGACATTTTGAACCCGGCGAAGGCGGCGGCGGTAGACCGCT
ACTTCCGCAAGGAGGAGGCCGGGCACTACTCGATTCTGCGGACGTCGGTGGTGCCGACGATCGTCAACATCGGGTTCCGG
TCGAACGTGATTCCGTCGGAGGGCGAGGCGATGCTGGATGTGCGCGCGCTGCCGGACGAGGACATGCCGAAGTTCATGGC
GGAGCTGCGGCGCGTGATCAACGATCCGGCAATCGAGGTGATTCCGCCGAAGGTGAACGCACGTCCGGTCTCAGCGCCCT
CGCGGATCGATACGGAGATGTTTCAGGTGCTCGAGGCAGTGGGGCGGCGCATGTTCAACGTGCCCACTCTGCCGGACATG
ATGACGGGCGCGACGGATAACGCGCAGCTGCGGGCGAAGGGAGTGCAGGCCTACGGGACGGGTCCGATTGTCAGCGCGGA
GGAGGGTCCGCTGGGCGGAGCGCATACGGACGATGAACATATTCCGGTGCGGTCGCTCATGGCGCTGATGGAATTCACGT
GGAACGCGGTGGTCGGCGTGGCGGCGACGAAGTAG

Upstream 100 bases:

>100_bases
TCGAGCCGCGGGAGACGCGGCCGCGAGTGATCCGCGCACTGCGCATGCTGGAGAACAAAGTGGACACGATGCCGCGCAAG
AAGCACGGCAACATACCGCT

Downstream 100 bases:

>100_bases
TGGCGTCGATTCGGACAGCGGGGCGAGCCGGCTGAAAGCCGGCTGCAGTCAGGATTGCCTGCCCCACAAGCTGGAGACCG
CGGTGCGTGTGTCTAGAGAT

Product: peptidase M20

Products: NA

Alternate protein names: SDAP desuccinylase [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKLMACLAMLAAGGLAQERYPVDWRKLEPEVLANFTALLKIDTSNPPGNETAAAKAIQGVLEREGIPCKLFAVDPARANL
VARIKGTGAKKPLLIMGHTDVVGVQREKWSFDPFAAINRNGVIYARGSRDDKPHVVAGIMTLLLLKRMKVKLDRDVIFLA
EAGEEGTTTFGIDYMVKEHWPEIEAEFAMAEGGSIVEQGGKPHHVLISTTEKSPQRVRLVAHGPAGHASRPEMTNAVVHL
AEAVAKAGNWQTPMRLNETTRVYFQRLAEISAPEAAARYRDILNPAKAAAVDRYFRKEEAGHYSILRTSVVPTIVNIGFR
SNVIPSEGEAMLDVRALPDEDMPKFMAELRRVINDPAIEVIPPKVNARPVSAPSRIDTEMFQVLEAVGRRMFNVPTLPDM
MTGATDNAQLRAKGVQAYGTGPIVSAEEGPLGGAHTDDEHIPVRSLMALMEFTWNAVVGVAATK

Sequences:

>Translated_464_residues
MKLMACLAMLAAGGLAQERYPVDWRKLEPEVLANFTALLKIDTSNPPGNETAAAKAIQGVLEREGIPCKLFAVDPARANL
VARIKGTGAKKPLLIMGHTDVVGVQREKWSFDPFAAINRNGVIYARGSRDDKPHVVAGIMTLLLLKRMKVKLDRDVIFLA
EAGEEGTTTFGIDYMVKEHWPEIEAEFAMAEGGSIVEQGGKPHHVLISTTEKSPQRVRLVAHGPAGHASRPEMTNAVVHL
AEAVAKAGNWQTPMRLNETTRVYFQRLAEISAPEAAARYRDILNPAKAAAVDRYFRKEEAGHYSILRTSVVPTIVNIGFR
SNVIPSEGEAMLDVRALPDEDMPKFMAELRRVINDPAIEVIPPKVNARPVSAPSRIDTEMFQVLEAVGRRMFNVPTLPDM
MTGATDNAQLRAKGVQAYGTGPIVSAEEGPLGGAHTDDEHIPVRSLMALMEFTWNAVVGVAATK
>Mature_464_residues
MKLMACLAMLAAGGLAQERYPVDWRKLEPEVLANFTALLKIDTSNPPGNETAAAKAIQGVLEREGIPCKLFAVDPARANL
VARIKGTGAKKPLLIMGHTDVVGVQREKWSFDPFAAINRNGVIYARGSRDDKPHVVAGIMTLLLLKRMKVKLDRDVIFLA
EAGEEGTTTFGIDYMVKEHWPEIEAEFAMAEGGSIVEQGGKPHHVLISTTEKSPQRVRLVAHGPAGHASRPEMTNAVVHL
AEAVAKAGNWQTPMRLNETTRVYFQRLAEISAPEAAARYRDILNPAKAAAVDRYFRKEEAGHYSILRTSVVPTIVNIGFR
SNVIPSEGEAMLDVRALPDEDMPKFMAELRRVINDPAIEVIPPKVNARPVSAPSRIDTEMFQVLEAVGRRMFNVPTLPDM
MTGATDNAQLRAKGVQAYGTGPIVSAEEGPLGGAHTDDEHIPVRSLMALMEFTWNAVVGVAATK

Specific function: Unknown

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=398, Percent_Identity=28.1407035175879, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI269846968, Length=381, Percent_Identity=25.7217847769029, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649210, Length=401, Percent_Identity=25.6857855361596, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 50616; Mature: 50616

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMACLAMLAAGGLAQERYPVDWRKLEPEVLANFTALLKIDTSNPPGNETAAAKAIQGV
CHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHH
LEREGIPCKLFAVDPARANLVARIKGTGAKKPLLIMGHTDVVGVQREKWSFDPFAAINRN
HHHCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCEECCC
GVIYARGSRDDKPHVVAGIMTLLLLKRMKVKLDRDVIFLAEAGEEGTTTFGIDYMVKEHW
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHCC
PEIEAEFAMAEGGSIVEQGGKPHHVLISTTEKSPQRVRLVAHGPAGHASRPEMTNAVVHL
CCCCCEEEECCCCHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
AEAVAKAGNWQTPMRLNETTRVYFQRLAEISAPEAAARYRDILNPAKAAAVDRYFRKEEA
HHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCC
GHYSILRTSVVPTIVNIGFRSNVIPSEGEAMLDVRALPDEDMPKFMAELRRVINDPAIEV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
IPPKVNARPVSAPSRIDTEMFQVLEAVGRRMFNVPTLPDMMTGATDNAQLRAKGVQAYGT
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEECCEEEECC
GPIVSAEEGPLGGAHTDDEHIPVRSLMALMEFTWNAVVGVAATK
CCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MKLMACLAMLAAGGLAQERYPVDWRKLEPEVLANFTALLKIDTSNPPGNETAAAKAIQGV
CHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHH
LEREGIPCKLFAVDPARANLVARIKGTGAKKPLLIMGHTDVVGVQREKWSFDPFAAINRN
HHHCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCEECCC
GVIYARGSRDDKPHVVAGIMTLLLLKRMKVKLDRDVIFLAEAGEEGTTTFGIDYMVKEHW
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEHHHHHHHCC
PEIEAEFAMAEGGSIVEQGGKPHHVLISTTEKSPQRVRLVAHGPAGHASRPEMTNAVVHL
CCCCCEEEECCCCHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHH
AEAVAKAGNWQTPMRLNETTRVYFQRLAEISAPEAAARYRDILNPAKAAAVDRYFRKEEA
HHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCC
GHYSILRTSVVPTIVNIGFRSNVIPSEGEAMLDVRALPDEDMPKFMAELRRVINDPAIEV
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
IPPKVNARPVSAPSRIDTEMFQVLEAVGRRMFNVPTLPDMMTGATDNAQLRAKGVQAYGT
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCEEEECCEEEECC
GPIVSAEEGPLGGAHTDDEHIPVRSLMALMEFTWNAVVGVAATK
CCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]