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The map label for this gene is secD [H]

Identifier: 116620401

GI number: 116620401

Start: 1575952

End: 1577571

Strand: Direct

Name: secD [H]

Synonym: Acid_1278

Alternate gene names: 116620401

Gene position: 1575952-1577571 (Clockwise)

Preceding gene: 116620400

Following gene: 116620402

Centisome position: 15.81

GC content: 59.57

Gene sequence:

>1620_bases
ATGAAGAAAAATCTAACGGCGCGAACCGTGATCATCGTTGTGACGATCCTGATCTGCGTGTTCGGCATCATCGGCATTCC
CAAGAGCGGCGCGGATATTGCGAGGAACTTCAGCGATAACATCCGCCTCGGGCTCGACCTTAAGGGCGGCACCCACCTGG
TGCTCGAAATCCAGGTGCAGGACGCGGTCAAAGCCGACGCCGATCAGACGGCGGAGCGCCTCAAAGAGGATCTCAAGAAG
CAGAACATCACGTGGGCCAGCATGGACACCCCCGACGTCGCCAAGGTGGAAGATGCCGACAATATGGCGATCACCATCAA
GGGTGTTCCGGCCACGCAATCCAGCGCGTTTCGCAGCCTGGTGGGCGAGCGTTATCCGACGTACCTGCTGACCGCGACCA
GCTCTACCGATTACACGATGAAGCTGAAGCCGACCGACCTGCAGGATCTGAAGGTGGACACGGTGAAGCGCGCGGTGGAT
ACCATCGGCAACCGTATCGACCAGCTCGGCCTGGCCGAGAAATCTGTGCAGCAGTACGGCGAGGCTGGCAAGAAGTACGA
AGTTCTGGTGCAACTGCCGGGCGTGGACGATCCGGCGCGCGCCAAGGAACTGATCGGCACGGCGGCGGTACTGGAGATTG
TGGACGTCAAGGAAGGTCCATTCCCAAGCCGCGAGGCGGCGCTTTCGCAGAAGGGCGGCATCCTGCCGCTGGGCACGAAG
CTGGCGCGCACCAAGCCGCGCGGCACGCAGGATGGGGAACAGTGGTACCTGGTTGCCAAGAATGCGGTGATTTCGGGCCG
GGAAATGCGAAATGCGCGTCCTGGACAGGATGAGTTCCGCAAGTGGGAAACCAACTTCAGCCTGTCGCAGGACGGCGGGC
GCCGGTTCGGCCGTTACACCGAAGCCAACATCGGCAACAAGCTCGGTGTGCTATTGGACAACCAGCTGGTGAGCGTGGCC
ACGATTCAATCGAAGATCGAAGATTCGGGCCGCATCACGGGTTTGGGCAGTGAAGAAGAAGCGGTGGATTTGTCGCGCTA
CCTGCGCAGCGGTTCGCTGCCGGCGGGCGTGGTGTATTTGCAGGAACGTTCGATCGGCCCGTCGCTTGGCGCCGATTCGA
TTCATCAGGGTCTGATGGCCGGTATCGCCGGATTGCTGGCGGTAATTGTGGTCATGCTCGTCTACTATAAGCGCTCCGGC
CTGAACGCGGTGCTGGCGCTGATATTGAACACGGTTCTGCTGCTCGCCGCGGTGTCTTATTTCCACGCGGTGCTCACCCT
TCCGGGGATCGCGGGAATCATCCTGACGATCGGTATGGCGGTAGATTCCAACGTGCTGATTTTCGAGCGTATCCGCGAGG
AACTGCGCAGCGGGAAGAGCGTGATCGCAGCCGTGGATGCGGGTTTTGGAAAGGCCTGGTGGACGATCGTCGATACCCAC
GTGACGACGGTTGTGTCCTGTGCTTTCCTGTTCCTGTTCGGCGAGGGGCCGGTTCGGGGATTTGCGGTAACATTGACAAT
CGGTTTGATCGCGAATATTTTCACCGCGGTTTTTGTATCGAAAACCATTTTCGATTACGAACTCTCCGGTCGCCGCCAGC
TTACTGAGCTGAGCATCTGA

Upstream 100 bases:

>100_bases
AGCTCCAGTTCGCGCGCAGCTCGGTGACCAGCAAGGTTGCCTCTACCCCCTCCGGAGACGGCAAGAAGTAGTACTCTATT
TAGGCAGGCTGTAAACTCCC

Downstream 100 bases:

>100_bases
GGCCTGGGCAGCTGGTTTATCAGCAGCTCGGGAACAAAAAATAAAGGGCTGGTGTCCAACGTTATGGAAAACACCAGCAC
GGCAAAGATTCGATGGAATT

Product: protein-export membrane protein SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKKNLTARTVIIVVTILICVFGIIGIPKSGADIARNFSDNIRLGLDLKGGTHLVLEIQVQDAVKADADQTAERLKEDLKK
QNITWASMDTPDVAKVEDADNMAITIKGVPATQSSAFRSLVGERYPTYLLTATSSTDYTMKLKPTDLQDLKVDTVKRAVD
TIGNRIDQLGLAEKSVQQYGEAGKKYEVLVQLPGVDDPARAKELIGTAAVLEIVDVKEGPFPSREAALSQKGGILPLGTK
LARTKPRGTQDGEQWYLVAKNAVISGREMRNARPGQDEFRKWETNFSLSQDGGRRFGRYTEANIGNKLGVLLDNQLVSVA
TIQSKIEDSGRITGLGSEEEAVDLSRYLRSGSLPAGVVYLQERSIGPSLGADSIHQGLMAGIAGLLAVIVVMLVYYKRSG
LNAVLALILNTVLLLAAVSYFHAVLTLPGIAGIILTIGMAVDSNVLIFERIREELRSGKSVIAAVDAGFGKAWWTIVDTH
VTTVVSCAFLFLFGEGPVRGFAVTLTIGLIANIFTAVFVSKTIFDYELSGRRQLTELSI

Sequences:

>Translated_539_residues
MKKNLTARTVIIVVTILICVFGIIGIPKSGADIARNFSDNIRLGLDLKGGTHLVLEIQVQDAVKADADQTAERLKEDLKK
QNITWASMDTPDVAKVEDADNMAITIKGVPATQSSAFRSLVGERYPTYLLTATSSTDYTMKLKPTDLQDLKVDTVKRAVD
TIGNRIDQLGLAEKSVQQYGEAGKKYEVLVQLPGVDDPARAKELIGTAAVLEIVDVKEGPFPSREAALSQKGGILPLGTK
LARTKPRGTQDGEQWYLVAKNAVISGREMRNARPGQDEFRKWETNFSLSQDGGRRFGRYTEANIGNKLGVLLDNQLVSVA
TIQSKIEDSGRITGLGSEEEAVDLSRYLRSGSLPAGVVYLQERSIGPSLGADSIHQGLMAGIAGLLAVIVVMLVYYKRSG
LNAVLALILNTVLLLAAVSYFHAVLTLPGIAGIILTIGMAVDSNVLIFERIREELRSGKSVIAAVDAGFGKAWWTIVDTH
VTTVVSCAFLFLFGEGPVRGFAVTLTIGLIANIFTAVFVSKTIFDYELSGRRQLTELSI
>Mature_539_residues
MKKNLTARTVIIVVTILICVFGIIGIPKSGADIARNFSDNIRLGLDLKGGTHLVLEIQVQDAVKADADQTAERLKEDLKK
QNITWASMDTPDVAKVEDADNMAITIKGVPATQSSAFRSLVGERYPTYLLTATSSTDYTMKLKPTDLQDLKVDTVKRAVD
TIGNRIDQLGLAEKSVQQYGEAGKKYEVLVQLPGVDDPARAKELIGTAAVLEIVDVKEGPFPSREAALSQKGGILPLGTK
LARTKPRGTQDGEQWYLVAKNAVISGREMRNARPGQDEFRKWETNFSLSQDGGRRFGRYTEANIGNKLGVLLDNQLVSVA
TIQSKIEDSGRITGLGSEEEAVDLSRYLRSGSLPAGVVYLQERSIGPSLGADSIHQGLMAGIAGLLAVIVVMLVYYKRSG
LNAVLALILNTVLLLAAVSYFHAVLTLPGIAGIILTIGMAVDSNVLIFERIREELRSGKSVIAAVDAGFGKAWWTIVDTH
VTTVVSCAFLFLFGEGPVRGFAVTLTIGLIANIFTAVFVSKTIFDYELSGRRQLTELSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=522, Percent_Identity=32.5670498084291, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1786610, Length=163, Percent_Identity=28.8343558282209, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 58284; Mature: 58284

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNLTARTVIIVVTILICVFGIIGIPKSGADIARNFSDNIRLGLDLKGGTHLVLEIQVQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEEEEEEH
DAVKADADQTAERLKEDLKKQNITWASMDTPDVAKVEDADNMAITIKGVPATQSSAFRSL
HHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCEEEEEECCCCCHHHHHHHH
VGERYPTYLLTATSSTDYTMKLKPTDLQDLKVDTVKRAVDTIGNRIDQLGLAEKSVQQYG
HHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EAGKKYEVLVQLPGVDDPARAKELIGTAAVLEIVDVKEGPFPSREAALSQKGGILPLGTK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEECCCH
LARTKPRGTQDGEQWYLVAKNAVISGREMRNARPGQDEFRKWETNFSLSQDGGRRFGRYT
HHCCCCCCCCCCCEEEEEECCCEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCHHCCCCC
EANIGNKLGVLLDNQLVSVATIQSKIEDSGRITGLGSEEEAVDLSRYLRSGSLPAGVVYL
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCEEEEE
QERSIGPSLGADSIHQGLMAGIAGLLAVIVVMLVYYKRSGLNAVLALILNTVLLLAAVSY
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FHAVLTLPGIAGIILTIGMAVDSNVLIFERIREELRSGKSVIAAVDAGFGKAWWTIVDTH
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHH
VTTVVSCAFLFLFGEGPVRGFAVTLTIGLIANIFTAVFVSKTIFDYELSGRRQLTELSI
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHCCC
>Mature Secondary Structure
MKKNLTARTVIIVVTILICVFGIIGIPKSGADIARNFSDNIRLGLDLKGGTHLVLEIQVQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEEEEEEH
DAVKADADQTAERLKEDLKKQNITWASMDTPDVAKVEDADNMAITIKGVPATQSSAFRSL
HHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEECCCCCEEEEEECCCCCHHHHHHHH
VGERYPTYLLTATSSTDYTMKLKPTDLQDLKVDTVKRAVDTIGNRIDQLGLAEKSVQQYG
HHCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EAGKKYEVLVQLPGVDDPARAKELIGTAAVLEIVDVKEGPFPSREAALSQKGGILPLGTK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHCCCEEECCCH
LARTKPRGTQDGEQWYLVAKNAVISGREMRNARPGQDEFRKWETNFSLSQDGGRRFGRYT
HHCCCCCCCCCCCEEEEEECCCEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCHHCCCCC
EANIGNKLGVLLDNQLVSVATIQSKIEDSGRITGLGSEEEAVDLSRYLRSGSLPAGVVYL
CCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCCCCCCEEEEE
QERSIGPSLGADSIHQGLMAGIAGLLAVIVVMLVYYKRSGLNAVLALILNTVLLLAAVSY
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FHAVLTLPGIAGIILTIGMAVDSNVLIFERIREELRSGKSVIAAVDAGFGKAWWTIVDTH
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCEEHHHHHHH
VTTVVSCAFLFLFGEGPVRGFAVTLTIGLIANIFTAVFVSKTIFDYELSGRRQLTELSI
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]