Click here to switch to the map view.

The map label for this gene is quiA [H]

Identifier: 116620306

GI number: 116620306

Start: 1456844

End: 1458964

Strand: Reverse

Name: quiA [H]

Synonym: Acid_1183

Alternate gene names: 116620306

Gene position: 1458964-1456844 (Counterclockwise)

Preceding gene: 116620307

Following gene: 116620305

Centisome position: 14.64

GC content: 66.34

Gene sequence:

>2121_bases
ATGCGCATTGTCTGCCTGGCGTTCCTGCTGTCGGCGTTGCCGCCGGCGTGGCCGCAAGCTATCCCGCCAGCCGGCGATTG
GCCGATGTACGGGCACGATGCGGGTGGAACGCGGTATTCGCCCCTGGACCAGATCAACACGAAGAACGTGGCGAAGCTGG
AGCGCGCGTGGACCTTTCATACCGGCGAGAGCGGCCGCAGTTTCGAGAGCACGCCGATCTTCGTGGACAACGTCCTGTAT
CTCTCGACGCACACGCAAAAGGTGATCGCGCTCGACCCGGTCACCGGGCGCGAGTTGTGGCGGTACGATACGCATGGCAC
GGGCCGGGAAAATCGCGGCGTGACGTACTGGCCGGGCGATGCGCAGGAAGGCGCGCGCATCCTGGTGGGCACGGGAGACG
GACGGCTGATTGCGCTTTCGGCAAAGACGGGCGTGCCGGTGCGGGGCTTCGGAGACAACGGCGTGATCAACCTGCGGGCG
GGGATCACCGACAAATTCCCCAAAGCGATGTACGCAATCACGTCCCCGCCGGCGATCTATCGCGATTTGGTGATTGTGGG
CCCGGCGACGCAGGAAGGGCCGTCGAGCGGTCCGAGCGGCGATCCGCGGGCGTTCGACGTGCGGACGGGGAAGCTGCGCT
GGCGGTTCCACGTGGGGCCGCAGGCGGGCGAGGCGGGAAGCGAGACGTGGGGACCGGAGGGATGGAAGGACCGGTCGGGG
CCGAGCCAGTGGGGCTTCGCGACGTTGGATACGGAGCGCGGCCTAGTGTTTCTTCCCGTGGGGAATCCCGCGGATAGTTT
TTATGGCGCGGACCGCAAGGGCACGAACCTGTACGCCAACTCGGTGATTGCGCTGGATGCCCTGACCGGGAAACTGCGCT
GGTATTACCAGGTGGTGCACCACGATATCTGGGACTACGACCTGGCCGCGCCGCCGGCGTTGATCGACGTCAAGCGCGAC
GGCAAGACGATTCCTGCGGTGGCGCAGATTACCAAGATGGGGCTGCTGTTCATCCTGGACCGCATAACTGGCAAACCGGT
GTTCGGGGTGGAGGAGCGGCGCGTGCCGAAGAGCGATGTTCCGGGCGAGGAAAGCTGGCCGACGCAGCCGTTTCCGCTGA
AGCCGCCGCCACTGGCGCGGATGAGCCTGACCGCGGCGGAGTTGACCACGCGGACTCCGGAGGCGCACAAATTCTGCGCG
GAATGGTTCGGGCGGCTACGGCACGAGGGCGCGTACACGCCGTTCGGGATGTCGCCGACGCTGATCATGCCGGGAACGAT
GGGCGGCGGAAATTGGGGTGGTGTGTCGTACGATCCGGGGCTCGGCTACATCTTCGTGAACACGAGCAGCCTGGGAGGGA
CGGGCCGGATGGCCCCGGCTCCGGCGGGATCGCCCATGCCCTACCGCAATGAAGGCGGATACACGCGATTCCTGGATCAG
GATCAGTTCCCCTGCCAGCAGCCGCCATGGGGCGAATTGAGCGCCGTTAACGCGAATACGGGTGAGATAGCGTGGCGGGT
GCCGCTGGGAAGCTACGACCAGGTGGAGGCGATGGGCCTGAAGAACGCGGGTGCATCGAATATGGGCGGGTCGATTGCGA
CGGCGGGCGGGCTGGTGTTCATCGGGGCGACGACCGACTCGAAGTTCCGCGCGTTCGATTCGCGGACCGGGAAAGAGCTG
TGGATGGGGCGGCTGGACGCGACCGGCGACGCGGTGCCGATGACGTACCGGGCGCGGAATGGGAAGCAGTATGTGGTGAT
CGCAGCGGCGGGGACGAATCGCTTCCGCATGATCGCGAATACGGCGGACGAGACGGCCGACTCGTTGATTGCGTTCACGC
TGGGAAACGGAGGGGCGCCGGAGAAGGCGCCAGCGGCCCGGACGCAATTGAGCGCGGCGGAGATGAAAGCTGCGGGTCCG
GCGCTGCCCGAGGGAGAGGGTAGGCAGGCGGTGACGAAGATGTGCACGAGCTGCCACGGCACGGCGGTGTTTACGGGAAT
CCGGATGAGCCGCGCGGGTTGGGACGCGGAGGTCGCCGCGATGGTGGAGAAGGGCGCGCAAGGGAGCGCGGGAGAGATCC
GGGCTGTGATTGGGTACCTGGCGGAGAACTACGGGAAATAG

Upstream 100 bases:

>100_bases
TACGCCGGCACGGCGGGCGTGAATCTGGCGCGCGAGTTCGTGCCGGGAATTGTCCGCCATTTTCGGAAGTAAGCATCCAG
TCGCGATATAGTAATTCGAC

Downstream 100 bases:

>100_bases
TGTTTGAATCAGTAGTGTATGAATCCTGAAGAATTTCGGCGCCGGGGGCATCAGATCATCGATCGGATTGCGGATTATCG
AGCCAATGTGGCGCGGTATC

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: NAD(P)-independent quinate dehydrogenase [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MRIVCLAFLLSALPPAWPQAIPPAGDWPMYGHDAGGTRYSPLDQINTKNVAKLERAWTFHTGESGRSFESTPIFVDNVLY
LSTHTQKVIALDPVTGRELWRYDTHGTGRENRGVTYWPGDAQEGARILVGTGDGRLIALSAKTGVPVRGFGDNGVINLRA
GITDKFPKAMYAITSPPAIYRDLVIVGPATQEGPSSGPSGDPRAFDVRTGKLRWRFHVGPQAGEAGSETWGPEGWKDRSG
PSQWGFATLDTERGLVFLPVGNPADSFYGADRKGTNLYANSVIALDALTGKLRWYYQVVHHDIWDYDLAAPPALIDVKRD
GKTIPAVAQITKMGLLFILDRITGKPVFGVEERRVPKSDVPGEESWPTQPFPLKPPPLARMSLTAAELTTRTPEAHKFCA
EWFGRLRHEGAYTPFGMSPTLIMPGTMGGGNWGGVSYDPGLGYIFVNTSSLGGTGRMAPAPAGSPMPYRNEGGYTRFLDQ
DQFPCQQPPWGELSAVNANTGEIAWRVPLGSYDQVEAMGLKNAGASNMGGSIATAGGLVFIGATTDSKFRAFDSRTGKEL
WMGRLDATGDAVPMTYRARNGKQYVVIAAAGTNRFRMIANTADETADSLIAFTLGNGGAPEKAPAARTQLSAAEMKAAGP
ALPEGEGRQAVTKMCTSCHGTAVFTGIRMSRAGWDAEVAAMVEKGAQGSAGEIRAVIGYLAENYGK

Sequences:

>Translated_706_residues
MRIVCLAFLLSALPPAWPQAIPPAGDWPMYGHDAGGTRYSPLDQINTKNVAKLERAWTFHTGESGRSFESTPIFVDNVLY
LSTHTQKVIALDPVTGRELWRYDTHGTGRENRGVTYWPGDAQEGARILVGTGDGRLIALSAKTGVPVRGFGDNGVINLRA
GITDKFPKAMYAITSPPAIYRDLVIVGPATQEGPSSGPSGDPRAFDVRTGKLRWRFHVGPQAGEAGSETWGPEGWKDRSG
PSQWGFATLDTERGLVFLPVGNPADSFYGADRKGTNLYANSVIALDALTGKLRWYYQVVHHDIWDYDLAAPPALIDVKRD
GKTIPAVAQITKMGLLFILDRITGKPVFGVEERRVPKSDVPGEESWPTQPFPLKPPPLARMSLTAAELTTRTPEAHKFCA
EWFGRLRHEGAYTPFGMSPTLIMPGTMGGGNWGGVSYDPGLGYIFVNTSSLGGTGRMAPAPAGSPMPYRNEGGYTRFLDQ
DQFPCQQPPWGELSAVNANTGEIAWRVPLGSYDQVEAMGLKNAGASNMGGSIATAGGLVFIGATTDSKFRAFDSRTGKEL
WMGRLDATGDAVPMTYRARNGKQYVVIAAAGTNRFRMIANTADETADSLIAFTLGNGGAPEKAPAARTQLSAAEMKAAGP
ALPEGEGRQAVTKMCTSCHGTAVFTGIRMSRAGWDAEVAAMVEKGAQGSAGEIRAVIGYLAENYGK
>Mature_706_residues
MRIVCLAFLLSALPPAWPQAIPPAGDWPMYGHDAGGTRYSPLDQINTKNVAKLERAWTFHTGESGRSFESTPIFVDNVLY
LSTHTQKVIALDPVTGRELWRYDTHGTGRENRGVTYWPGDAQEGARILVGTGDGRLIALSAKTGVPVRGFGDNGVINLRA
GITDKFPKAMYAITSPPAIYRDLVIVGPATQEGPSSGPSGDPRAFDVRTGKLRWRFHVGPQAGEAGSETWGPEGWKDRSG
PSQWGFATLDTERGLVFLPVGNPADSFYGADRKGTNLYANSVIALDALTGKLRWYYQVVHHDIWDYDLAAPPALIDVKRD
GKTIPAVAQITKMGLLFILDRITGKPVFGVEERRVPKSDVPGEESWPTQPFPLKPPPLARMSLTAAELTTRTPEAHKFCA
EWFGRLRHEGAYTPFGMSPTLIMPGTMGGGNWGGVSYDPGLGYIFVNTSSLGGTGRMAPAPAGSPMPYRNEGGYTRFLDQ
DQFPCQQPPWGELSAVNANTGEIAWRVPLGSYDQVEAMGLKNAGASNMGGSIATAGGLVFIGATTDSKFRAFDSRTGKEL
WMGRLDATGDAVPMTYRARNGKQYVVIAAAGTNRFRMIANTADETADSLIAFTLGNGGAPEKAPAARTQLSAAEMKAAGP
ALPEGEGRQAVTKMCTSCHGTAVFTGIRMSRAGWDAEVAAMVEKGAQGSAGEIRAVIGYLAENYGK

Specific function: Can act either on quinate or on shikimate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=652, Percent_Identity=35.4294478527607, Blast_Score=353, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.25 [H]

Molecular weight: Translated: 75713; Mature: 75713

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVCLAFLLSALPPAWPQAIPPAGDWPMYGHDAGGTRYSPLDQINTKNVAKLERAWTFH
CEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHEEEEE
TGESGRSFESTPIFVDNVLYLSTHTQKVIALDPVTGRELWRYDTHGTGRENRGVTYWPGD
CCCCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCCHHEEECCCCCCCCCCCEEECCCC
AQEGARILVGTGDGRLIALSAKTGVPVRGFGDNGVINLRAGITDKFPKAMYAITSPPAIY
CCCCCEEEEECCCCEEEEEECCCCCCEEECCCCCEEEEECCCCCCCCCCEEEECCCCHHH
RDLVIVGPATQEGPSSGPSGDPRAFDVRTGKLRWRFHVGPQAGEAGSETWGPEGWKDRSG
EEEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
PSQWGFATLDTERGLVFLPVGNPADSFYGADRKGTNLYANSVIALDALTGKLRWYYQVVH
CCCCCEEEEECCCCEEEEECCCCCHHHCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHH
HDIWDYDLAAPPALIDVKRDGKTIPAVAQITKMGLLFILDRITGKPVFGVEERRVPKSDV
HCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
PGEESWPTQPFPLKPPPLARMSLTAAELTTRTPEAHKFCAEWFGRLRHEGAYTPFGMSPT
CCCCCCCCCCCCCCCCCCHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIMPGTMGGGNWGGVSYDPGLGYIFVNTSSLGGTGRMAPAPAGSPMPYRNEGGYTRFLDQ
EEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
DQFPCQQPPWGELSAVNANTGEIAWRVPLGSYDQVEAMGLKNAGASNMGGSIATAGGLVF
CCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEECCCEEE
IGATTDSKFRAFDSRTGKELWMGRLDATGDAVPMTYRARNGKQYVVIAAAGTNRFRMIAN
EEECCCCHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEC
TADETADSLIAFTLGNGGAPEKAPAARTQLSAAEMKAAGPALPEGEGRQAVTKMCTSCHG
CHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
TAVFTGIRMSRAGWDAEVAAMVEKGAQGSAGEIRAVIGYLAENYGK
CEEEEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIVCLAFLLSALPPAWPQAIPPAGDWPMYGHDAGGTRYSPLDQINTKNVAKLERAWTFH
CEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHEEEEE
TGESGRSFESTPIFVDNVLYLSTHTQKVIALDPVTGRELWRYDTHGTGRENRGVTYWPGD
CCCCCCCCCCCCEEEEEEEEEEECCCEEEEECCCCCCHHEEECCCCCCCCCCCEEECCCC
AQEGARILVGTGDGRLIALSAKTGVPVRGFGDNGVINLRAGITDKFPKAMYAITSPPAIY
CCCCCEEEEECCCCEEEEEECCCCCCEEECCCCCEEEEECCCCCCCCCCEEEECCCCHHH
RDLVIVGPATQEGPSSGPSGDPRAFDVRTGKLRWRFHVGPQAGEAGSETWGPEGWKDRSG
EEEEEECCCCCCCCCCCCCCCCEEEEEEECEEEEEEEECCCCCCCCCCCCCCCCCCCCCC
PSQWGFATLDTERGLVFLPVGNPADSFYGADRKGTNLYANSVIALDALTGKLRWYYQVVH
CCCCCEEEEECCCCEEEEECCCCCHHHCCCCCCCCEEEECCEEEEEHHHHHHHHHHHHHH
HDIWDYDLAAPPALIDVKRDGKTIPAVAQITKMGLLFILDRITGKPVFGVEERRVPKSDV
HCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
PGEESWPTQPFPLKPPPLARMSLTAAELTTRTPEAHKFCAEWFGRLRHEGAYTPFGMSPT
CCCCCCCCCCCCCCCCCCHHEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
LIMPGTMGGGNWGGVSYDPGLGYIFVNTSSLGGTGRMAPAPAGSPMPYRNEGGYTRFLDQ
EEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCC
DQFPCQQPPWGELSAVNANTGEIAWRVPLGSYDQVEAMGLKNAGASNMGGSIATAGGLVF
CCCCCCCCCCCCEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCEEECCCEEE
IGATTDSKFRAFDSRTGKELWMGRLDATGDAVPMTYRARNGKQYVVIAAAGTNRFRMIAN
EEECCCCHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEC
TADETADSLIAFTLGNGGAPEKAPAARTQLSAAEMKAAGPALPEGEGRQAVTKMCTSCHG
CHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCC
TAVFTGIRMSRAGWDAEVAAMVEKGAQGSAGEIRAVIGYLAENYGK
CEEEEEEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002591; 7592351 [H]