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The map label for this gene is hflX [H]

Identifier: 116620284

GI number: 116620284

Start: 1432165

End: 1433349

Strand: Reverse

Name: hflX [H]

Synonym: Acid_1161

Alternate gene names: 116620284

Gene position: 1433349-1432165 (Counterclockwise)

Preceding gene: 116620285

Following gene: 116620281

Centisome position: 14.38

GC content: 65.65

Gene sequence:

>1185_bases
ATGCAGACGCGTCCCGCTCCGGAAGCTGCCACGCTCATCGGGCAAGGCAAGGTCGAAGAACTCGCGGCCTCCGTACTCTC
CACCGAAGCCGATGTAGTGATCTTCGATCAGGATCTCTCGCCGACGCAGCAGCGCAACCTCGAGAAGGCGCTCGCGACCA
AGGTCATCGACCGGACCCAGCTCATCCTCGATATTTTTGCCTCGCGCGCCCGAACTCGGGAGGGCCGGCTGCAGGTGGAA
CTCGCGCAGCTGAATTACCTGCTGCCCCGGCTGGCCGGCCGCGGCGTTCAGATGTCGCGGCTCGGCGGCGGCATCGGCAC
CCGCGGTCCCGGTGAAACGCAGTTGGAAACCGATCGCCGGCGCATCGCCAAACGCATTAAGAAAGTGGAGGACGAACTGG
AAGGTGTCCGCGCCGGGCGGGCGCTGCACCGCCGCCGCCGCAGCGCCGTGCCGCTTGCGACTCTGGCACTCGCCGGCTAC
ACCAACGCCGGCAAATCCACGCTTTTCAACCGGCTCACCCGTGCCAGCGTGCTGGCCGATTCCAAAATGTTCGCGACGCT
CGATCCCACGGTGCGGCCGCTGGTGCTGCCCTCGCGGCGACGCGTCCTGATGAGCGACACGGTGGGGTTCATCCGCAACC
TGCCCACCACACTGGTCAAAGCCTTCCGCGCAACCTTGGAAGAGGTGAATGAAGCCGCCCTCATCCTGCACGTGGTGGAC
GCCTCTTCGCCGACTGCGCCGGAACATACCGCCCACGTACTCAAGGTCCTCGCCGAAATCGGTGCGCACGAAGTCCCGCA
GATCCTGGTGTTGAATAAGGTGGACCTGCTGGCCGCCGGCGATGCCGATGCCGCCAGCCTGCAACGCCGCCTGCTGGCTG
GTCTCGGCGCAGCCCATGGAGAGGACGATCCCGACCCATCGGTCTTCAGCGGCAAGATGCGCGCAGTGGCGATCTCCGCC
ACAAGCGGCGCAGGCATCGACACCTTGATGGCAGCAATCGACGAGGTGCTGCCCCTGGACCCGGTGGTTCGGGCGACGCT
CGATCTCGATTCAGGCGACGGGGCAACGCTGGCGCTGCTCCACGAATTCGGGCGGGTGATCGAGACCCGCTATCACGACG
ATCGGGTCGAAGTCGAAGTTGATCTGCCGGAGTCGCTGGAACGTCGCCTCCGCTCGCGACAATAA

Upstream 100 bases:

>100_bases
TGGAGGAGGCGGGCGAACCAACGCTCTTCGAGCCGAAGAGTCCCTGGACGAGCTCGCCGAGCTGGCCGCCAGCGCGGGGG
CGGAAATCCTCGACCGCGTC

Downstream 100 bases:

>100_bases
AGATCGGAATTGCTCGCATTCAACGATCCACAGATCTGTGGAAAACTCTGTTAAAAAGTGGCGTCACGCTCCAGTAAAGT
TGTGTAAGCGAACGAACTTA

Product: HSR1-like GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQTRPAPEAATLIGQGKVEELAASVLSTEADVVIFDQDLSPTQQRNLEKALATKVIDRTQLILDIFASRARTREGRLQVE
LAQLNYLLPRLAGRGVQMSRLGGGIGTRGPGETQLETDRRRIAKRIKKVEDELEGVRAGRALHRRRRSAVPLATLALAGY
TNAGKSTLFNRLTRASVLADSKMFATLDPTVRPLVLPSRRRVLMSDTVGFIRNLPTTLVKAFRATLEEVNEAALILHVVD
ASSPTAPEHTAHVLKVLAEIGAHEVPQILVLNKVDLLAAGDADAASLQRRLLAGLGAAHGEDDPDPSVFSGKMRAVAISA
TSGAGIDTLMAAIDEVLPLDPVVRATLDLDSGDGATLALLHEFGRVIETRYHDDRVEVEVDLPESLERRLRSRQ

Sequences:

>Translated_394_residues
MQTRPAPEAATLIGQGKVEELAASVLSTEADVVIFDQDLSPTQQRNLEKALATKVIDRTQLILDIFASRARTREGRLQVE
LAQLNYLLPRLAGRGVQMSRLGGGIGTRGPGETQLETDRRRIAKRIKKVEDELEGVRAGRALHRRRRSAVPLATLALAGY
TNAGKSTLFNRLTRASVLADSKMFATLDPTVRPLVLPSRRRVLMSDTVGFIRNLPTTLVKAFRATLEEVNEAALILHVVD
ASSPTAPEHTAHVLKVLAEIGAHEVPQILVLNKVDLLAAGDADAASLQRRLLAGLGAAHGEDDPDPSVFSGKMRAVAISA
TSGAGIDTLMAAIDEVLPLDPVVRATLDLDSGDGATLALLHEFGRVIETRYHDDRVEVEVDLPESLERRLRSRQ
>Mature_394_residues
MQTRPAPEAATLIGQGKVEELAASVLSTEADVVIFDQDLSPTQQRNLEKALATKVIDRTQLILDIFASRARTREGRLQVE
LAQLNYLLPRLAGRGVQMSRLGGGIGTRGPGETQLETDRRRIAKRIKKVEDELEGVRAGRALHRRRRSAVPLATLALAGY
TNAGKSTLFNRLTRASVLADSKMFATLDPTVRPLVLPSRRRVLMSDTVGFIRNLPTTLVKAFRATLEEVNEAALILHVVD
ASSPTAPEHTAHVLKVLAEIGAHEVPQILVLNKVDLLAAGDADAASLQRRLLAGLGAAHGEDDPDPSVFSGKMRAVAISA
TSGAGIDTLMAAIDEVLPLDPVVRATLDLDSGDGATLALLHEFGRVIETRYHDDRVEVEVDLPESLERRLRSRQ

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=247, Percent_Identity=33.1983805668016, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI310124269, Length=233, Percent_Identity=33.9055793991416, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI310124267, Length=233, Percent_Identity=33.9055793991416, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI310124171, Length=233, Percent_Identity=33.9055793991416, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI310124169, Length=233, Percent_Identity=33.9055793991416, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI310133118, Length=257, Percent_Identity=32.6848249027237, Blast_Score=105, Evalue=7e-23,
Organism=Escherichia coli, GI1790615, Length=393, Percent_Identity=44.0203562340967, Blast_Score=285, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=274, Percent_Identity=31.7518248175182, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24650079, Length=287, Percent_Identity=33.4494773519164, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42692; Mature: 42692

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTRPAPEAATLIGQGKVEELAASVLSTEADVVIFDQDLSPTQQRNLEKALATKVIDRTQ
CCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LILDIFASRARTREGRLQVELAQLNYLLPRLAGRGVQMSRLGGGIGTRGPGETQLETDRR
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
RIAKRIKKVEDELEGVRAGRALHRRRRSAVPLATLALAGYTNAGKSTLFNRLTRASVLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
SKMFATLDPTVRPLVLPSRRRVLMSDTVGFIRNLPTTLVKAFRATLEEVNEAALILHVVD
CCCEEECCCCCCCEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEE
ASSPTAPEHTAHVLKVLAEIGAHEVPQILVLNKVDLLAAGDADAASLQRRLLAGLGAAHG
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCC
EDDPDPSVFSGKMRAVAISATSGAGIDTLMAAIDEVLPLDPVVRATLDLDSGDGATLALL
CCCCCCCHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHH
HEFGRVIETRYHDDRVEVEVDLPESLERRLRSRQ
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MQTRPAPEAATLIGQGKVEELAASVLSTEADVVIFDQDLSPTQQRNLEKALATKVIDRTQ
CCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LILDIFASRARTREGRLQVELAQLNYLLPRLAGRGVQMSRLGGGIGTRGPGETQLETDRR
HHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
RIAKRIKKVEDELEGVRAGRALHRRRRSAVPLATLALAGYTNAGKSTLFNRLTRASVLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
SKMFATLDPTVRPLVLPSRRRVLMSDTVGFIRNLPTTLVKAFRATLEEVNEAALILHVVD
CCCEEECCCCCCCEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEEE
ASSPTAPEHTAHVLKVLAEIGAHEVPQILVLNKVDLLAAGDADAASLQRRLLAGLGAAHG
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEECCCCCHHHHHHHHHHHHCCCCC
EDDPDPSVFSGKMRAVAISATSGAGIDTLMAAIDEVLPLDPVVRATLDLDSGDGATLALL
CCCCCCCHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHEEECCCCCCHHHHHH
HEFGRVIETRYHDDRVEVEVDLPESLERRLRSRQ
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]