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The map label for this gene is 116620212

Identifier: 116620212

GI number: 116620212

Start: 1337723

End: 1338640

Strand: Direct

Name: 116620212

Synonym: Acid_1085

Alternate gene names: NA

Gene position: 1337723-1338640 (Clockwise)

Preceding gene: 116620211

Following gene: 116620218

Centisome position: 13.42

GC content: 61.55

Gene sequence:

>918_bases
ATGTTGCCATACCGGTTCGTTTACCACGATCGCTACGATCTGAACCTCGGGGAACATGTGTTCCCATCCCAGAAATTTCG
CTGGCTTCGCGACCGGCTACTGCATACGCGCTTCGCCGCCGCAGAGGATTTCGTAACTCCGGAATCCGCCACCGACGACG
ACGTCCGCCTGGTGCACGACCCCGAGTACGTCGCCAAACTGCGCGGCGGCACGTTGAGTTACCAGGACATTCTTCGCCTC
GAGATTCCCTACTCGCGCCAAATGGTGGAGGCCTTCTGGCTGGCTGCCGGTGGATCGATTCTGGCTGCACGGCTGGCATT
GCAGGACGGCATCGGCTTCAACATCGGCGGCGGCTTTCATCACGCGTTCCCTGGGCACGGAGAAGGCTTCTGCGCGATCA
ACGATGTCGCGATCGCAGTGCGGCGCCTGCAGGCTGACCGGCTGATCAAGCGCGCCATGGTGGTGGATTGCGACGTGCAT
CACGGCAACGGCACCGCGGCAATCTTCACTGACGACCAATCCGTCTTCACGCTTTCCATTCACCAGTTCAATAATTATCC
GAGCGAGAAGCCGCTCTCGAGCCTCGACATTCACCTCACGGACGGTATCGGCGACGCTGAGTATCTCCATCGTCTCGGCA
ACGGCTACCGCGCGGCCCTGACGATGTTCAAGCCCGAACTCTTGATGTATGTCGCCGGTGCCGACCCCTACATGGAAGAT
CAGCTGGGCGGTCTCTCGCTGACCTTCGAAGGCCTGATGGAGCGCGACCGCCTCGTGATCCGCACCGCGCTCACCCACAG
TGTCCCGGTGGCGATCGTGCTCGCCGGCGGCTACGCGCAGAGCGTGGAAGACACGATCACGATTCACGCCAACACCGCGG
CCGTGGCCAAGGACGTCCTCGGCAAAGTGCGTTTGTAG

Upstream 100 bases:

>100_bases
CGGCCAACGATCTTTCGAGAGGGTGTTCGGCCGAGGACATTTTCAATGTGGCGGTGGTGACTGCGCTGCAATCGGAGATA
CACTAACGGCGCACCCGGCC

Downstream 100 bases:

>100_bases
ACCCGCTCCGGTTCTCCTGCTCGATCACGCATGTAGCCTCGGCGCTCCTTCAAAGCCGCGTCAGTCAATGTCGGATCGAT
CAATGTCAGCTGGGTTTCCG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLPYRFVYHDRYDLNLGEHVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHDPEYVAKLRGGTLSYQDILRL
EIPYSRQMVEAFWLAAGGSILAARLALQDGIGFNIGGGFHHAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVVDCDVH
HGNGTAAIFTDDQSVFTLSIHQFNNYPSEKPLSSLDIHLTDGIGDAEYLHRLGNGYRAALTMFKPELLMYVAGADPYMED
QLGGLSLTFEGLMERDRLVIRTALTHSVPVAIVLAGGYAQSVEDTITIHANTAAVAKDVLGKVRL

Sequences:

>Translated_305_residues
MLPYRFVYHDRYDLNLGEHVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHDPEYVAKLRGGTLSYQDILRL
EIPYSRQMVEAFWLAAGGSILAARLALQDGIGFNIGGGFHHAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVVDCDVH
HGNGTAAIFTDDQSVFTLSIHQFNNYPSEKPLSSLDIHLTDGIGDAEYLHRLGNGYRAALTMFKPELLMYVAGADPYMED
QLGGLSLTFEGLMERDRLVIRTALTHSVPVAIVLAGGYAQSVEDTITIHANTAAVAKDVLGKVRL
>Mature_305_residues
MLPYRFVYHDRYDLNLGEHVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHDPEYVAKLRGGTLSYQDILRL
EIPYSRQMVEAFWLAAGGSILAARLALQDGIGFNIGGGFHHAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVVDCDVH
HGNGTAAIFTDDQSVFTLSIHQFNNYPSEKPLSSLDIHLTDGIGDAEYLHRLGNGYRAALTMFKPELLMYVAGADPYMED
QLGGLSLTFEGLMERDRLVIRTALTHSVPVAIVLAGGYAQSVEDTITIHANTAAVAKDVLGKVRL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=300, Percent_Identity=29.6666666666667, Blast_Score=141, Evalue=7e-34,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=29.7794117647059, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI13128860, Length=303, Percent_Identity=24.4224422442244, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI293336691, Length=268, Percent_Identity=25.7462686567164, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI8923769, Length=256, Percent_Identity=25.390625, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI13128864, Length=304, Percent_Identity=29.9342105263158, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI13128862, Length=181, Percent_Identity=28.1767955801105, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI262073092, Length=187, Percent_Identity=28.3422459893048, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI20070354, Length=291, Percent_Identity=28.5223367697594, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI62750349, Length=281, Percent_Identity=27.7580071174377, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI62750347, Length=281, Percent_Identity=27.7580071174377, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI30795202, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795204, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI17158039, Length=149, Percent_Identity=30.8724832214765, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI148539870, Length=165, Percent_Identity=32.1212121212121, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI169234807, Length=165, Percent_Identity=32.1212121212121, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI153085395, Length=148, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226529806, Length=167, Percent_Identity=32.3353293413174, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI262073088, Length=171, Percent_Identity=25.1461988304094, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=296, Percent_Identity=30.7432432432432, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17561978, Length=316, Percent_Identity=26.8987341772152, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17508561, Length=260, Percent_Identity=29.2307692307692, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534739, Length=249, Percent_Identity=26.9076305220884, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=253, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17540334, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193206283, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540332, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209491, Length=317, Percent_Identity=25.5520504731861, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=295, Percent_Identity=28.135593220339, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323999, Length=296, Percent_Identity=23.9864864864865, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=177, Percent_Identity=31.0734463276836, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=281, Percent_Identity=24.1992882562278, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649807, Length=258, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24657891, Length=303, Percent_Identity=27.3927392739274, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644244, Length=282, Percent_Identity=25.886524822695, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360899, Length=314, Percent_Identity=27.0700636942675, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642146, Length=314, Percent_Identity=27.0700636942675, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642144, Length=314, Percent_Identity=27.0700636942675, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642142, Length=314, Percent_Identity=27.0700636942675, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33841; Mature: 33841

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPYRFVYHDRYDLNLGEHVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHD
CCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
PEYVAKLRGGTLSYQDILRLEIPYSRQMVEAFWLAAGGSILAARLALQDGIGFNIGGGFH
HHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
HAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVVDCDVHHGNGTAAIFTDDQSVFTLSI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCEEEEEE
HQFNNYPSEKPLSSLDIHLTDGIGDAEYLHRLGNGYRAALTMFKPELLMYVAGADPYMED
EECCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEHHHHCCCEEEEEEECCCCCHHH
QLGGLSLTFEGLMERDRLVIRTALTHSVPVAIVLAGGYAQSVEDTITIHANTAAVAKDVL
CCCCEEEEHHHHHCCCCEEEEHHHHCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHH
GKVRL
HHCCC
>Mature Secondary Structure
MLPYRFVYHDRYDLNLGEHVFPSQKFRWLRDRLLHTRFAAAEDFVTPESATDDDVRLVHD
CCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
PEYVAKLRGGTLSYQDILRLEIPYSRQMVEAFWLAAGGSILAARLALQDGIGFNIGGGFH
HHHHHHHCCCCCCHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
HAFPGHGEGFCAINDVAIAVRRLQADRLIKRAMVVDCDVHHGNGTAAIFTDDQSVFTLSI
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEEECCCCEEEEEE
HQFNNYPSEKPLSSLDIHLTDGIGDAEYLHRLGNGYRAALTMFKPELLMYVAGADPYMED
EECCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEHHHHCCCEEEEEEECCCCCHHH
QLGGLSLTFEGLMERDRLVIRTALTHSVPVAIVLAGGYAQSVEDTITIHANTAAVAKDVL
CCCCEEEEHHHHHCCCCEEEEHHHHCCCCEEEEEECCCCCCCCCEEEEEECHHHHHHHHH
GKVRL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]