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The map label for this gene is tsr [H]

Identifier: 116620196

GI number: 116620196

Start: 1321459

End: 1323060

Strand: Direct

Name: tsr [H]

Synonym: Acid_1069

Alternate gene names: 116620196

Gene position: 1321459-1323060 (Clockwise)

Preceding gene: 116620195

Following gene: 116620204

Centisome position: 13.26

GC content: 62.42

Gene sequence:

>1602_bases
ATGAATTCGCAGATGACGATCGGCAAGAAGCTCATGCTCAGCTTCGCCGGACTGATTGTTTTGCTGGTCACCCTGAGTTT
CACGTTCCTGAGCGTGGTTGGCACGCTCAAGGGGACCTTCGATGAGGCAGTGGATAAGACTGCGAGGAAGCTCTCACTGG
CCGGCGACCTGGACGCGGCGGAGTCAGACATGCTTGCGTGGCAGCGCGGCATGCTTCTTTACGCGCTGAGCAAGGACACT
GCAAAGTCTGAGGCCGCCAGAGGAAGATTCCGGAAATCGCTGGAAAGCGCCAACCAGGCACTGACGGAGATCACCCCCCT
CCTGGTCAATGAGGAAGGTCGGAAATTGACGGCATCCACTAAGGCCGGACTCAACGCGTGGGCGAATCACTTCGCTGAAT
CCGATCGTCTTTGTGCGGCGGGCGATCCCTCGGCGGGGTTTCAGTATGCAGCGACGAATACGGTTTCGATCTTCGAGGAG
CTGACCGGCCAGGTGACCCGGCTGAAGGAAATTCAAAACGCTCGTTTGCAGGAAAACCGTGCCGAAGCATCCGCGGAGAA
TATAAGCAGTCGCTGGATTGCCTTTGTGATGCTTGCGCTCTCACTCGGCCTGGGGGCTATCGTGTTCCTGGTGGTGCGCC
AGATCAGCGGTGTGCTCCAAAAAACGGCGGCAGAGATGGCCGAAGGGGCGGGCCAGGTGGCAAGTGCGGCTTCGCAGGTG
GCCGTCTCCAGCCAATCGCTTGCGCAGGGTTCCTCGGAGCAGGCGGCGTCGATCGAAGAAACGTCGGCTGCGACGGAAGA
GATTCACTCGATGGCGCGGCGGAATACTGAGAACTCGAACTCCGCGGCGGCGCTGGTGGCGCAGTCGCAACGGCAGTTCG
AGGACACGAGGACGTCGTTGAACGCGATGGTGACGGCGATGACGGACATCACCACGTCGAGCGGGAAGATTTCCAAGATC
ATCAAGGTGATCGACGAGATTGCCTTCCAGACCAACATCCTGGCGTTGAACGCGGCAGTGGAAGCGGCGCGCGCCGGCGA
GGCTGGGCTGGGCTTTGCGGTGGTGGCGGACGAGGTACGCAACCTGGCGCAGCGGTGCGCCCAGGCCGCCAAAGATACCG
CCGACCTGATCGAGGACTCGGTGGCGAAATCCAACGCAGGCAAGGCCAAGGTGGACCAGGTAGCGGATGCCATCCGGATG
GTCACGGAGGAGGCGGGCAAGATTAAAGTGCTGGTAGATGAAATTAGCGTGGGGAGCCAGGAGCAGGCGCGGGGCATCGA
GCAGATCGGCTCGGCGATCACGCAGATGGACCAGGTGACGCAACGCGCGGCGGCGAGCGCGGAGGAAGGCGCCTCGGCGG
CCGAGGAACTGACGGCGCAATCGGAATCGTTGAAGGCCGTGGTGGGCGAGTTGACCCGAATGGTAGGGGGCGGCGAGCCT
GTGCGGGCCATGGCGCGCAGCCAGTCGCCGGCCGGCCGGCACAGTGGGCCGGGGCTGGCGAAGATGGCGGCGGCCGTAGC
GCGTCATGATCCTACAACTTCGCGGGACATGGTCGCACTGGGCGTCGAGAAAGATCCCTTCCCTATGGACGGGGATTTCT
AG

Upstream 100 bases:

>100_bases
GTAGCGCCGCCTGGTTCAGCCAACCCCTAAGGTATTCCTCAATCACTGCCGATAAGACACTTGCAGATGGTTAAGCCCTG
CAAGTGAGGTAATGCGTCCT

Downstream 100 bases:

>100_bases
AGTAGCTGCCGGGCGCGGCTGGCGGTAGCGGCGCCGATCAGCGCCAGGTCGTGGCTGTTGCGCACGAGTTCAAAGAAGCT
GCCCTGAAGCGGGCTCATCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MNSQMTIGKKLMLSFAGLIVLLVTLSFTFLSVVGTLKGTFDEAVDKTARKLSLAGDLDAAESDMLAWQRGMLLYALSKDT
AKSEAARGRFRKSLESANQALTEITPLLVNEEGRKLTASTKAGLNAWANHFAESDRLCAAGDPSAGFQYAATNTVSIFEE
LTGQVTRLKEIQNARLQENRAEASAENISSRWIAFVMLALSLGLGAIVFLVVRQISGVLQKTAAEMAEGAGQVASAASQV
AVSSQSLAQGSSEQAASIEETSAATEEIHSMARRNTENSNSAAALVAQSQRQFEDTRTSLNAMVTAMTDITTSSGKISKI
IKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRCAQAAKDTADLIEDSVAKSNAGKAKVDQVADAIRM
VTEEAGKIKVLVDEISVGSQEQARGIEQIGSAITQMDQVTQRAAASAEEGASAAEELTAQSESLKAVVGELTRMVGGGEP
VRAMARSQSPAGRHSGPGLAKMAAAVARHDPTTSRDMVALGVEKDPFPMDGDF

Sequences:

>Translated_533_residues
MNSQMTIGKKLMLSFAGLIVLLVTLSFTFLSVVGTLKGTFDEAVDKTARKLSLAGDLDAAESDMLAWQRGMLLYALSKDT
AKSEAARGRFRKSLESANQALTEITPLLVNEEGRKLTASTKAGLNAWANHFAESDRLCAAGDPSAGFQYAATNTVSIFEE
LTGQVTRLKEIQNARLQENRAEASAENISSRWIAFVMLALSLGLGAIVFLVVRQISGVLQKTAAEMAEGAGQVASAASQV
AVSSQSLAQGSSEQAASIEETSAATEEIHSMARRNTENSNSAAALVAQSQRQFEDTRTSLNAMVTAMTDITTSSGKISKI
IKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRCAQAAKDTADLIEDSVAKSNAGKAKVDQVADAIRM
VTEEAGKIKVLVDEISVGSQEQARGIEQIGSAITQMDQVTQRAAASAEEGASAAEELTAQSESLKAVVGELTRMVGGGEP
VRAMARSQSPAGRHSGPGLAKMAAAVARHDPTTSRDMVALGVEKDPFPMDGDF
>Mature_533_residues
MNSQMTIGKKLMLSFAGLIVLLVTLSFTFLSVVGTLKGTFDEAVDKTARKLSLAGDLDAAESDMLAWQRGMLLYALSKDT
AKSEAARGRFRKSLESANQALTEITPLLVNEEGRKLTASTKAGLNAWANHFAESDRLCAAGDPSAGFQYAATNTVSIFEE
LTGQVTRLKEIQNARLQENRAEASAENISSRWIAFVMLALSLGLGAIVFLVVRQISGVLQKTAAEMAEGAGQVASAASQV
AVSSQSLAQGSSEQAASIEETSAATEEIHSMARRNTENSNSAAALVAQSQRQFEDTRTSLNAMVTAMTDITTSSGKISKI
IKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVRNLAQRCAQAAKDTADLIEDSVAKSNAGKAKVDQVADAIRM
VTEEAGKIKVLVDEISVGSQEQARGIEQIGSAITQMDQVTQRAAASAEEGASAAEELTAQSESLKAVVGELTRMVGGGEP
VRAMARSQSPAGRHSGPGLAKMAAAVARHDPTTSRDMVALGVEKDPFPMDGDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=387, Percent_Identity=35.6589147286822, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1788194, Length=265, Percent_Identity=40, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1787690, Length=279, Percent_Identity=39.0681003584229, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1788195, Length=227, Percent_Identity=40.9691629955947, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789453, Length=226, Percent_Identity=34.9557522123894, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56006; Mature: 56006

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSQMTIGKKLMLSFAGLIVLLVTLSFTFLSVVGTLKGTFDEAVDKTARKLSLAGDLDAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ESDMLAWQRGMLLYALSKDTAKSEAARGRFRKSLESANQALTEITPLLVNEEGRKLTAST
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
KAGLNAWANHFAESDRLCAAGDPSAGFQYAATNTVSIFEELTGQVTRLKEIQNARLQENR
HHHHHHHHHHHHCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEASAENISSRWIAFVMLALSLGLGAIVFLVVRQISGVLQKTAAEMAEGAGQVASAASQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSSQSLAQGSSEQAASIEETSAATEEIHSMARRNTENSNSAAALVAQSQRQFEDTRTSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NAMVTAMTDITTSSGKISKIIKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
NLAQRCAQAAKDTADLIEDSVAKSNAGKAKVDQVADAIRMVTEEAGKIKVLVDEISVGSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
EQARGIEQIGSAITQMDQVTQRAAASAEEGASAAEELTAQSESLKAVVGELTRMVGGGEP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRAMARSQSPAGRHSGPGLAKMAAAVARHDPTTSRDMVALGVEKDPFPMDGDF
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNSQMTIGKKLMLSFAGLIVLLVTLSFTFLSVVGTLKGTFDEAVDKTARKLSLAGDLDAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ESDMLAWQRGMLLYALSKDTAKSEAARGRFRKSLESANQALTEITPLLVNEEGRKLTAST
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
KAGLNAWANHFAESDRLCAAGDPSAGFQYAATNTVSIFEELTGQVTRLKEIQNARLQENR
HHHHHHHHHHHHCCCCEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEASAENISSRWIAFVMLALSLGLGAIVFLVVRQISGVLQKTAAEMAEGAGQVASAASQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSSQSLAQGSSEQAASIEETSAATEEIHSMARRNTENSNSAAALVAQSQRQFEDTRTSL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
NAMVTAMTDITTSSGKISKIIKVIDEIAFQTNILALNAAVEAARAGEAGLGFAVVADEVR
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
NLAQRCAQAAKDTADLIEDSVAKSNAGKAKVDQVADAIRMVTEEAGKIKVLVDEISVGSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
EQARGIEQIGSAITQMDQVTQRAAASAEEGASAAEELTAQSESLKAVVGELTRMVGGGEP
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VRAMARSQSPAGRHSGPGLAKMAAAVARHDPTTSRDMVALGVEKDPFPMDGDF
HHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]