Click here to switch to the map view.

The map label for this gene is aes [C]

Identifier: 116620204

GI number: 116620204

Start: 1328644

End: 1330293

Strand: Direct

Name: aes [C]

Synonym: Acid_1077

Alternate gene names: 116620204

Gene position: 1328644-1330293 (Clockwise)

Preceding gene: 116620196

Following gene: 116620207

Centisome position: 13.33

GC content: 65.03

Gene sequence:

>1650_bases
ATGCTTGCTCGATTGACAATTCTTGCCGCGGCCTCCGCCTGTGCGCTGGTGGGCCAGGCGCTCAAAATTCCCGACACGGT
GATTGCCGATCGCGATGTGGAGTACTCAGCGGTAGGAGGGCGGCAGACCCTGGACATCGTACGGTCGCGCGAGGGGTCGG
GCGCTCCGCGGCCGGCGATTCTGCTGGTCCACGGCGGAGGCTTTCGCGCCGGCGCGAAGGAGAGCTACCTGCCGCTCGCC
ATTAAACTCGCGGAGCGCGGCTATGTGGCCGCCACGGCGAACTACCGGCTCTCACCGCGCAACCAGTTTCCAGCCGCCGT
GGAAGACGTCAAGGCCGCGGTTCGTTTCCTGCGTGCCGGAGCCGCGAAGTACAACCTCGATCCCGCGCACATCGGCGCGC
TCGGCGGCAGCGCCGGAGGTCACCTGGTGCTGATGCTCGGCCTCACGGCCGGGGTGGCGGAGTTCGAGGGCTCGGGGCCG
AATCGCGAGCAATCGAGCGCGGTGCAGTGCGTGGTCGATGAGTACGGGCCCACGGATTTCACGCAGTCCTACTCCAAATC
GGTAGATGCCGCCGAGGTGCTGCCGATGTTCCTCGGCGGAAATCTCGATCACGAACGCGCGGCGCACATGCGGGCGAGCC
CGCTCAACTGGGTGACGCCCAACGCCGCGCCGATCCTGGCTATCCATGGCACGGCGGACACCTATGTGGCCTACGAGCAA
TCGCTGTGGATCGTCGAGCGGCTGATCGCGGCGGGCGTCCCGGCGGAGTTGGAAACCATCTCTGGCGCGGGCCACGGCTT
TAAGGGCGCCGATGCCTTGCGCGCGGACGAGCGCGCGTTTGCCTGGTTCGACAAATACCTGAAGCCAGCGCCTGCCGCGC
ACCGGCTGCTGATCTCCGATCACGGCCCGAACGGCGAGATCGCCGAAATCGAGTGGCCTTCCGGCAACGTGCTGTGGAGC
GCGCCCAACGATCACGGGCATGACGTGCAGTCGCTCCCCGAGGGACACGTGCTGTTCACCATCAACCCGCGGAAGCGCGT
GGTGGAACTCGATAGCGCTCACCACGAGGTCTGGAGCTATAACGAGGCACTGGAGCATCCCATCGCGGCGCAGCGGTTGG
ACAATGGGAACACGCTGATCAGCGATGCCAAACTCGGCAAAGTTATCGAAGTGACTCCCGCCGGGCAGGGCGCCTGGAAA
TACGAAAGCTCCGACCTCGCCAACATGCGCTCACGCAACGCGCACCGCACCGAAGAAGGCACCACGCTGATCGCGGTCGA
GGCCGACGCCAAGTTGATCGAGGTGGACGCGGCGGGGAAGATTGTCTGGCAGTGGCAGGCGCCGAACGCAAAGAATCGCA
AGCTCTACATGGGCCGCAGGCTCAAGAACGGCAACACTGTCGTGAGCTTGTCCGATCCCGGCGAAGTTGTCGAGGTCGAT
CGCACCGGAAAAATTGTGCGCTCCATCGGCGGCGCGGATCCGGCCGTACAAATGGGCTGGGCCTCGGGCTTCGCCTTTCT
GCCCGGCGGTGGAATGCTGATCAACGATTACACGGGCCGTCGCATCATCGAGGTCGATGCCAAAGGCAAGGTGGTCAATC
AGTGGCGAACCGGCTCGCGCACGATCGCGAGCATTGACCTAGTCCGGTAG

Upstream 100 bases:

>100_bases
GAGCACGAACTCGTGAGGGATGCGTTTTCGAGGGCGGGTCGCCATGGGTCTAGAATAACTGCCTTTGACTGGCGCGTCCG
GATCGCGTATAGTCGCGTCG

Downstream 100 bases:

>100_bases
CGGTTACGCCAGCGCGAGATTCAGGTTCTCGATGGCTTCGTCGATTTCCTTCGTATTCTTGAAGCCGACCGTGACCGAAT
CGACACCGGCATTGTTGAAT

Product: alpha/beta hydrolase domain-containing protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Domain-Containing Protein; Lipase/Esterase; Esterase/Lipase; Esterase/Lipase-Like Protein; Lipase; Esterase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase; Esterase/Lipase/Thioesterase; Esterase/Lipase/Thioesterase Family Protein; Alpha/Beta Hydrolase Fold Domain Protein; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Carboxylesterase Family Protein; Esterase LipC; Esterase LipO; Xylan Esterase; Esterase/Lipase-Like; Acetyl Esterase Family; Triacylglycerol Lipase; Acetyl Esterase; Dienelactone Hydrolase; Peptidase S; Lipoprotein; Membrane-Bound Esterase LipM; Pectinesterase; Alpha/Beta Hydrolase Fold Protein; Membrane-Anchored Peptidase; Esterase-Hydrolase; Alpha/Beta Hydrolase Fold Family Protein; Coagulation Factor 5/8 Type Domain Protein; Lipase/Esterase Protein; Carboxylesterase LipQ; Lipase Esterase; Dipeptidyl Aminopeptidases/Acylaminoacyl-Peptidases-Like; Carboxylesterase; Peptidase; Endo-1 4-Beta-Xylanase B; Hydrolase; Prolyl Oligopeptidase Family Protein; Pyrrolo-Quinoline Quinone; Alpha/Beta Hydrolase Protein; Peptidase S9A/B/C Families; Para-Nitrobenzyl Esterase; Esterase LipM; Heroin Esterase

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MLARLTILAAASACALVGQALKIPDTVIADRDVEYSAVGGRQTLDIVRSREGSGAPRPAILLVHGGGFRAGAKESYLPLA
IKLAERGYVAATANYRLSPRNQFPAAVEDVKAAVRFLRAGAAKYNLDPAHIGALGGSAGGHLVLMLGLTAGVAEFEGSGP
NREQSSAVQCVVDEYGPTDFTQSYSKSVDAAEVLPMFLGGNLDHERAAHMRASPLNWVTPNAAPILAIHGTADTYVAYEQ
SLWIVERLIAAGVPAELETISGAGHGFKGADALRADERAFAWFDKYLKPAPAAHRLLISDHGPNGEIAEIEWPSGNVLWS
APNDHGHDVQSLPEGHVLFTINPRKRVVELDSAHHEVWSYNEALEHPIAAQRLDNGNTLISDAKLGKVIEVTPAGQGAWK
YESSDLANMRSRNAHRTEEGTTLIAVEADAKLIEVDAAGKIVWQWQAPNAKNRKLYMGRRLKNGNTVVSLSDPGEVVEVD
RTGKIVRSIGGADPAVQMGWASGFAFLPGGGMLINDYTGRRIIEVDAKGKVVNQWRTGSRTIASIDLVR

Sequences:

>Translated_549_residues
MLARLTILAAASACALVGQALKIPDTVIADRDVEYSAVGGRQTLDIVRSREGSGAPRPAILLVHGGGFRAGAKESYLPLA
IKLAERGYVAATANYRLSPRNQFPAAVEDVKAAVRFLRAGAAKYNLDPAHIGALGGSAGGHLVLMLGLTAGVAEFEGSGP
NREQSSAVQCVVDEYGPTDFTQSYSKSVDAAEVLPMFLGGNLDHERAAHMRASPLNWVTPNAAPILAIHGTADTYVAYEQ
SLWIVERLIAAGVPAELETISGAGHGFKGADALRADERAFAWFDKYLKPAPAAHRLLISDHGPNGEIAEIEWPSGNVLWS
APNDHGHDVQSLPEGHVLFTINPRKRVVELDSAHHEVWSYNEALEHPIAAQRLDNGNTLISDAKLGKVIEVTPAGQGAWK
YESSDLANMRSRNAHRTEEGTTLIAVEADAKLIEVDAAGKIVWQWQAPNAKNRKLYMGRRLKNGNTVVSLSDPGEVVEVD
RTGKIVRSIGGADPAVQMGWASGFAFLPGGGMLINDYTGRRIIEVDAKGKVVNQWRTGSRTIASIDLVR
>Mature_549_residues
MLARLTILAAASACALVGQALKIPDTVIADRDVEYSAVGGRQTLDIVRSREGSGAPRPAILLVHGGGFRAGAKESYLPLA
IKLAERGYVAATANYRLSPRNQFPAAVEDVKAAVRFLRAGAAKYNLDPAHIGALGGSAGGHLVLMLGLTAGVAEFEGSGP
NREQSSAVQCVVDEYGPTDFTQSYSKSVDAAEVLPMFLGGNLDHERAAHMRASPLNWVTPNAAPILAIHGTADTYVAYEQ
SLWIVERLIAAGVPAELETISGAGHGFKGADALRADERAFAWFDKYLKPAPAAHRLLISDHGPNGEIAEIEWPSGNVLWS
APNDHGHDVQSLPEGHVLFTINPRKRVVELDSAHHEVWSYNEALEHPIAAQRLDNGNTLISDAKLGKVIEVTPAGQGAWK
YESSDLANMRSRNAHRTEEGTTLIAVEADAKLIEVDAAGKIVWQWQAPNAKNRKLYMGRRLKNGNTVVSLSDPGEVVEVD
RTGKIVRSIGGADPAVQMGWASGFAFLPGGGMLINDYTGRRIIEVDAKGKVVNQWRTGSRTIASIDLVR

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 58791; Mature: 58791

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLARLTILAAASACALVGQALKIPDTVIADRDVEYSAVGGRQTLDIVRSREGSGAPRPAI
CCEEEEHHHHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCHHHHHHHCCCCCCCCCCEE
LLVHGGGFRAGAKESYLPLAIKLAERGYVAATANYRLSPRNQFPAAVEDVKAAVRFLRAG
EEEECCCCCCCCCCCCCEEEEEEECCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHHCC
AAKYNLDPAHIGALGGSAGGHLVLMLGLTAGVAEFEGSGPNREQSSAVQCVVDEYGPTDF
CCCCCCCHHHHEECCCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHH
TQSYSKSVDAAEVLPMFLGGNLDHERAAHMRASPLNWVTPNAAPILAIHGTADTYVAYEQ
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCEECCCCCEEEEEECCCCCEEEEHH
SLWIVERLIAAGVPAELETISGAGHGFKGADALRADERAFAWFDKYLKPAPAAHRLLISD
HHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCEEEEEEC
HGPNGEIAEIEWPSGNVLWSAPNDHGHDVQSLPEGHVLFTINPRKRVVELDSAHHEVWSY
CCCCCCEEEEECCCCCEEEECCCCCCCCHHHCCCCCEEEEECCCCEEEEECCCHHHHHHH
NEALEHPIAAQRLDNGNTLISDAKLGKVIEVTPAGQGAWKYESSDLANMRSRNAHRTEEG
HHHHCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCC
TTLIAVEADAKLIEVDAAGKIVWQWQAPNAKNRKLYMGRRLKNGNTVVSLSDPGEVVEVD
CEEEEEECCCEEEEEECCCEEEEEEECCCCCCCEEEECEEECCCCEEEEECCCCCEEEEC
RTGKIVRSIGGADPAVQMGWASGFAFLPGGGMLINDYTGRRIIEVDAKGKVVNQWRTGSR
CCCHHHHHCCCCCCCEEEECCCCEEECCCCCEEEECCCCCEEEEECCCCCEEEECCCCCC
TIASIDLVR
EEEEEEECC
>Mature Secondary Structure
MLARLTILAAASACALVGQALKIPDTVIADRDVEYSAVGGRQTLDIVRSREGSGAPRPAI
CCEEEEHHHHHHHHHHHHHHHCCCCCEECCCCCCEEECCCCHHHHHHHCCCCCCCCCCEE
LLVHGGGFRAGAKESYLPLAIKLAERGYVAATANYRLSPRNQFPAAVEDVKAAVRFLRAG
EEEECCCCCCCCCCCCCEEEEEEECCCEEEEEECEEECCCCCCCHHHHHHHHHHHHHHCC
AAKYNLDPAHIGALGGSAGGHLVLMLGLTAGVAEFEGSGPNREQSSAVQCVVDEYGPTDF
CCCCCCCHHHHEECCCCCCCEEEEEEECCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHH
TQSYSKSVDAAEVLPMFLGGNLDHERAAHMRASPLNWVTPNAAPILAIHGTADTYVAYEQ
HHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCEECCCCCEEEEEECCCCCEEEEHH
SLWIVERLIAAGVPAELETISGAGHGFKGADALRADERAFAWFDKYLKPAPAAHRLLISD
HHHHHHHHHHCCCCHHHHEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCEEEEEEC
HGPNGEIAEIEWPSGNVLWSAPNDHGHDVQSLPEGHVLFTINPRKRVVELDSAHHEVWSY
CCCCCCEEEEECCCCCEEEECCCCCCCCHHHCCCCCEEEEECCCCEEEEECCCHHHHHHH
NEALEHPIAAQRLDNGNTLISDAKLGKVIEVTPAGQGAWKYESSDLANMRSRNAHRTEEG
HHHHCCCHHHHHCCCCCEEEECCCCCCEEEEECCCCCCEEECCCHHHHHHHCCCCCCCCC
TTLIAVEADAKLIEVDAAGKIVWQWQAPNAKNRKLYMGRRLKNGNTVVSLSDPGEVVEVD
CEEEEEECCCEEEEEECCCEEEEEEECCCCCCCEEEECEEECCCCEEEEECCCCCEEEEC
RTGKIVRSIGGADPAVQMGWASGFAFLPGGGMLINDYTGRRIIEVDAKGKVVNQWRTGSR
CCCHHHHHCCCCCCCEEEECCCCEEECCCCCEEEECCCCCEEEEECCCCCEEEECCCCCC
TIASIDLVR
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA