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The map label for this gene is sldA [H]

Identifier: 116620171

GI number: 116620171

Start: 1289451

End: 1291496

Strand: Direct

Name: sldA [H]

Synonym: Acid_1044

Alternate gene names: 116620171

Gene position: 1289451-1291496 (Clockwise)

Preceding gene: 116620170

Following gene: 116620173

Centisome position: 12.94

GC content: 65.59

Gene sequence:

>2046_bases
ATGATCCGATCGCTAGCGTTCGCCCTCGCCTCCGTTCGACTGCTTGCCGCCTCGGATTGGCCGGGGTACGGTGGCGGCCC
CGCGGGGATTCGTCACTCGCCCTTGAAGCAGATCAATCGCTCCAACGTGTCGCACCTCAAGGTCGCGTGGACGTACGACA
CCAAGGATGGGCCGGGCGATCCACAGACGCAGCCGATCGTGGTCGATGGCGTTCTCTATGGCGTAACTCCGACCCACAAA
GCCATCGCGCTAAACGGCGCCACCGGAAAGCTGCTGTGGACCTTCGACTCCGGCATTCGCGGACGTGGTCCCAATCGCTC
GGTAGTCTGGTGGTCGCCGCGAACGGAGCGGCGGCTCTTCGTCGCGGTGCAGAGCTTTATCTACGCGCTCGACCCAGCCA
CCGGGAAGCCCATGGCGGATTTCGGCGAGCAGGGCCGCATCGATCTCCGCCAGGGCCTGGGGCGCGATGCCGCCAAGCAG
TCCTACGTCCTGACCAGCCCGGGAATTATTTATCGCGATCTGTTGATCGTGGGCGGCCGCCTGCCGGAAGCGCTGCCGGC
GCCGCCCGGCGACATCCGCGCCTATGATGTCCGCACCGGCAAACAGCGCTGGACCTTCCACACGATTCCGCATCCGGGCG
AGCCCGGCTACGAGACCTGGCCCTCCGATGCCTGGACCTACTCCGGCGGCGCCAACAACTGGGCCGGCATGGCGCTCGAC
GAGAAGCGTGGCATCGTCTACGTCCCCACCGGCTCAGCCGCCAGCGATTTTTATGGCGCCGACCGCCTGGGCGACAACCT
CTACGCCAACTGCCTGCTGGCGCTGAACGCCGCCACCGGCGAGCGCGTCTGGCACTTCCAGGCGGTGCATCATGACATCT
GGGATCGTGACTTTCCCTCCCCGCCCGCGCTGGTCACCGTCCGGCACGAAGGCCGCACGGTCGATGCCGTTGTGCAGACC
TCCAAGCAGGGCTGGGTCTACCTGTTCAATCGCGCCACCGGCAAGCCGTTGTTCCCCATCGAGAGCCGGCCCTATCCCGT
CAGCGAGCTGCCGGGCGAACGTGCTGCCGCCGAACAGTCGCTCCCGACCAGGCCGGCCGCCTTTGCGCGCCAGGCTCTGA
CTGAAGACGTGCTCACCCGCCGCACCGATGCAACCCACGCGTGGGCGCTTGCCGAGTTCCACAAGCTGCGCAGCGCCGGA
CAGTTCCTGCCCTTCGGGGCAGGGAATGAGACCGTCATTTTTCCAGGCTTCGATGGCGGCGCCGAGTGGGGCGGTCCGGC
CTTCGATCCCTCCACGGGATTGCTGTACGTCAACGCCAATGAAATGGCCTGGAGGGCGGGCCTCAAGGAATCCCAGCCGG
AAAACTCAGCCCGGCAACTGTATGTGGCGCAGTGCGGCACCTGCCATGGCGACGACCTCAAGGGCTCGCCTCCGCAGTTC
CCGGCGTTGAACGACCTTGCCGGAAAGCGCTCGGCCCAGGAAATCGGCGCAATCATTCGCGAGGGCGGCGGGCGCATGCC
TGCTTTCCCCCGGCTTCGTCCCGACGACATCACCGCGCTCAGCGATTATCTGCTCCGCGGCCGCAGCAAGGAGCTGGAGA
GCACCGCCTCACTGGATCGCGAACCGCGATTTCGTTTTACCGGCTATCACAAGTTCGTCGATCCCGATGGCTATCCGGCA
ATCGCGCCGCCGTGGGGCACGCTCAACGCCATCAACCTCAATACCGGCGAATACGCGTGGCGCATCCCGCTCGGCGAATA
TCCCGACCTCGCGGCCAAAAACACGGGATCGGAAAACTACGGCGGCCCCATCGTGACCGCCGGCGGCCTCGTGTTTATCG
CGGCCACCAACTATGACCGCAAGTTCCGAGCCTTCGACAAGGCCACCGGCGAACTGCTCTGGCAGACTACGCTCCCGATG
GCCGGCAACGCCACACCCATCACCTATGAAATCGCCGGCCGCCAGTACGTCGTGATCTACGCGACCGGCGGCAAGTCCGG
CAAGTGGGGTCCTTCGGGCGGAATCTACATGGCGTTCTCACTGTAA

Upstream 100 bases:

>100_bases
AACGTTAACGACGCCGATCATTCTCCTTCAGGCAAGCCTATCCTGGCTTCCGCCGGCCTTCAGCCGGCGCGACCCGGAGT
CTGCGCTATTCTTCCTATAA

Downstream 100 bases:

>100_bases
TCCGCGCGTGATAGGCAGACTTGCATGGTATCGGCGGACGTTGGCCATGCCGTGCGCACTTTGCGCGCCAGCCCCGGCTT
CAGCCTGTCTGCCACCGCGA

Product: quinoprotein glucose dehydrogenase

Products: NA

Alternate protein names: D-arabitol dehydrogenase large subunit; ARDH; D-sorbitol dehydrogenase subunit sldA; SLDH; Gluconate/polyol dehydrogenase large subunit [H]

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MIRSLAFALASVRLLAASDWPGYGGGPAGIRHSPLKQINRSNVSHLKVAWTYDTKDGPGDPQTQPIVVDGVLYGVTPTHK
AIALNGATGKLLWTFDSGIRGRGPNRSVVWWSPRTERRLFVAVQSFIYALDPATGKPMADFGEQGRIDLRQGLGRDAAKQ
SYVLTSPGIIYRDLLIVGGRLPEALPAPPGDIRAYDVRTGKQRWTFHTIPHPGEPGYETWPSDAWTYSGGANNWAGMALD
EKRGIVYVPTGSAASDFYGADRLGDNLYANCLLALNAATGERVWHFQAVHHDIWDRDFPSPPALVTVRHEGRTVDAVVQT
SKQGWVYLFNRATGKPLFPIESRPYPVSELPGERAAAEQSLPTRPAAFARQALTEDVLTRRTDATHAWALAEFHKLRSAG
QFLPFGAGNETVIFPGFDGGAEWGGPAFDPSTGLLYVNANEMAWRAGLKESQPENSARQLYVAQCGTCHGDDLKGSPPQF
PALNDLAGKRSAQEIGAIIREGGGRMPAFPRLRPDDITALSDYLLRGRSKELESTASLDREPRFRFTGYHKFVDPDGYPA
IAPPWGTLNAINLNTGEYAWRIPLGEYPDLAAKNTGSENYGGPIVTAGGLVFIAATNYDRKFRAFDKATGELLWQTTLPM
AGNATPITYEIAGRQYVVIYATGGKSGKWGPSGGIYMAFSL

Sequences:

>Translated_681_residues
MIRSLAFALASVRLLAASDWPGYGGGPAGIRHSPLKQINRSNVSHLKVAWTYDTKDGPGDPQTQPIVVDGVLYGVTPTHK
AIALNGATGKLLWTFDSGIRGRGPNRSVVWWSPRTERRLFVAVQSFIYALDPATGKPMADFGEQGRIDLRQGLGRDAAKQ
SYVLTSPGIIYRDLLIVGGRLPEALPAPPGDIRAYDVRTGKQRWTFHTIPHPGEPGYETWPSDAWTYSGGANNWAGMALD
EKRGIVYVPTGSAASDFYGADRLGDNLYANCLLALNAATGERVWHFQAVHHDIWDRDFPSPPALVTVRHEGRTVDAVVQT
SKQGWVYLFNRATGKPLFPIESRPYPVSELPGERAAAEQSLPTRPAAFARQALTEDVLTRRTDATHAWALAEFHKLRSAG
QFLPFGAGNETVIFPGFDGGAEWGGPAFDPSTGLLYVNANEMAWRAGLKESQPENSARQLYVAQCGTCHGDDLKGSPPQF
PALNDLAGKRSAQEIGAIIREGGGRMPAFPRLRPDDITALSDYLLRGRSKELESTASLDREPRFRFTGYHKFVDPDGYPA
IAPPWGTLNAINLNTGEYAWRIPLGEYPDLAAKNTGSENYGGPIVTAGGLVFIAATNYDRKFRAFDKATGELLWQTTLPM
AGNATPITYEIAGRQYVVIYATGGKSGKWGPSGGIYMAFSL
>Mature_681_residues
MIRSLAFALASVRLLAASDWPGYGGGPAGIRHSPLKQINRSNVSHLKVAWTYDTKDGPGDPQTQPIVVDGVLYGVTPTHK
AIALNGATGKLLWTFDSGIRGRGPNRSVVWWSPRTERRLFVAVQSFIYALDPATGKPMADFGEQGRIDLRQGLGRDAAKQ
SYVLTSPGIIYRDLLIVGGRLPEALPAPPGDIRAYDVRTGKQRWTFHTIPHPGEPGYETWPSDAWTYSGGANNWAGMALD
EKRGIVYVPTGSAASDFYGADRLGDNLYANCLLALNAATGERVWHFQAVHHDIWDRDFPSPPALVTVRHEGRTVDAVVQT
SKQGWVYLFNRATGKPLFPIESRPYPVSELPGERAAAEQSLPTRPAAFARQALTEDVLTRRTDATHAWALAEFHKLRSAG
QFLPFGAGNETVIFPGFDGGAEWGGPAFDPSTGLLYVNANEMAWRAGLKESQPENSARQLYVAQCGTCHGDDLKGSPPQF
PALNDLAGKRSAQEIGAIIREGGGRMPAFPRLRPDDITALSDYLLRGRSKELESTASLDREPRFRFTGYHKFVDPDGYPA
IAPPWGTLNAINLNTGEYAWRIPLGEYPDLAAKNTGSENYGGPIVTAGGLVFIAATNYDRKFRAFDKATGELLWQTTLPM
AGNATPITYEIAGRQYVVIYATGGKSGKWGPSGGIYMAFSL

Specific function: Catalyzes the oxidation of glycerol to glycerone. Also acts, more slowly, on a number of other polyols including D- sorbitol, D-arabinitol, D-mannitol, meso-erythritol, adonitol and propylene glycol [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=481, Percent_Identity=30.3534303534304, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.22 [H]

Molecular weight: Translated: 74149; Mature: 74149

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSLAFALASVRLLAASDWPGYGGGPAGIRHSPLKQINRSNVSHLKVAWTYDTKDGPGD
CHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCC
PQTQPIVVDGVLYGVTPTHKAIALNGATGKLLWTFDSGIRGRGPNRSVVWWSPRTERRLF
CCCCCEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCHH
VAVQSFIYALDPATGKPMADFGEQGRIDLRQGLGRDAAKQSYVLTSPGIIYRDLLIVGGR
HHHHHHHHEECCCCCCCHHHCCCCCCCHHHHCCCCCHHHCCEEEECCCHHHHHHHHCCCC
LPEALPAPPGDIRAYDVRTGKQRWTFHTIPHPGEPGYETWPSDAWTYSGGANNWAGMALD
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCEEEE
EKRGIVYVPTGSAASDFYGADRLGDNLYANCLLALNAATGERVWHFQAVHHDIWDRDFPS
CCCCEEEEECCCCCHHCCCHHHCCCHHHEEEEEEEECCCCCEEEEEEHHHHHHCCCCCCC
PPALVTVRHEGRTVDAVVQTSKQGWVYLFNRATGKPLFPIESRPYPVSELPGERAAAEQS
CCCEEEEECCCCEEEHHEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCHHHHHHC
LPTRPAAFARQALTEDVLTRRTDATHAWALAEFHKLRSAGQFLPFGAGNETVIFPGFDGG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
AEWGGPAFDPSTGLLYVNANEMAWRAGLKESQPENSARQLYVAQCGTCHGDDLKGSPPQF
CCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
PALNDLAGKRSAQEIGAIIREGGGRMPAFPRLRPDDITALSDYLLRGRSKELESTASLDR
CCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
EPRFRFTGYHKFVDPDGYPAIAPPWGTLNAINLNTGEYAWRIPLGEYPDLAAKNTGSENY
CCCEEEECEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCC
GGPIVTAGGLVFIAATNYDRKFRAFDKATGELLWQTTLPMAGNATPITYEIAGRQYVVIY
CCCEEEECCEEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCEEEEEE
ATGGKSGKWGPSGGIYMAFSL
EECCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MIRSLAFALASVRLLAASDWPGYGGGPAGIRHSPLKQINRSNVSHLKVAWTYDTKDGPGD
CHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCC
PQTQPIVVDGVLYGVTPTHKAIALNGATGKLLWTFDSGIRGRGPNRSVVWWSPRTERRLF
CCCCCEEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCHH
VAVQSFIYALDPATGKPMADFGEQGRIDLRQGLGRDAAKQSYVLTSPGIIYRDLLIVGGR
HHHHHHHHEECCCCCCCHHHCCCCCCCHHHHCCCCCHHHCCEEEECCCHHHHHHHHCCCC
LPEALPAPPGDIRAYDVRTGKQRWTFHTIPHPGEPGYETWPSDAWTYSGGANNWAGMALD
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCEEEE
EKRGIVYVPTGSAASDFYGADRLGDNLYANCLLALNAATGERVWHFQAVHHDIWDRDFPS
CCCCEEEEECCCCCHHCCCHHHCCCHHHEEEEEEEECCCCCEEEEEEHHHHHHCCCCCCC
PPALVTVRHEGRTVDAVVQTSKQGWVYLFNRATGKPLFPIESRPYPVSELPGERAAAEQS
CCCEEEEECCCCEEEHHEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHCCCCHHHHHHC
LPTRPAAFARQALTEDVLTRRTDATHAWALAEFHKLRSAGQFLPFGAGNETVIFPGFDGG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCC
AEWGGPAFDPSTGLLYVNANEMAWRAGLKESQPENSARQLYVAQCGTCHGDDLKGSPPQF
CCCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCHHHEEEEEECCCCCCCCCCCCCCCC
PALNDLAGKRSAQEIGAIIREGGGRMPAFPRLRPDDITALSDYLLRGRSKELESTASLDR
CCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
EPRFRFTGYHKFVDPDGYPAIAPPWGTLNAINLNTGEYAWRIPLGEYPDLAAKNTGSENY
CCCEEEECEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCC
GGPIVTAGGLVFIAATNYDRKFRAFDKATGELLWQTTLPMAGNATPITYEIAGRQYVVIY
CCCEEEECCEEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCEEEEEE
ATGGKSGKWGPSGGIYMAFSL
EECCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA