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The map label for this gene is macB [H]

Identifier: 116620111

GI number: 116620111

Start: 1224805

End: 1227240

Strand: Reverse

Name: macB [H]

Synonym: Acid_0984

Alternate gene names: 116620111

Gene position: 1227240-1224805 (Counterclockwise)

Preceding gene: 116620112

Following gene: 116620109

Centisome position: 12.31

GC content: 66.79

Gene sequence:

>2436_bases
ATGAGCACGGTCCTACAGAACGCCCGATTTGGGCTGCGGGTGTTTCGACGCGCGCCCGGGTTCGCGGCCGTGGCGGTTCT
CACGCTCGCGGTAGGGATCGGCGCCAACACCTCCATCTTCAGCGTCGCCAACGCGCTGCTGCTCCGGCCATTGGCCTACG
AGAAACCCGACCGGTTGGTGCTGATCAACTCGCACCGCAAGAGCGCCAACCTGAGCCAGGGTCCGCTCTCTTTCACGCGC
TTCGAAGAGGTGGATCAGCGCAGCCGCAGCTTCACCGGCGTGGGGGCGTTCACCTCCGAAGTCTTCAACCTGACCGGCAA
CGGCGATCCGGAGCAGATTCTCTCGGCGCGCGTCAGCTGGAAGTTTTTTCCCGTGCTCGGCGTCTCCCCGGCGCTCGGGC
GCAGCTTCCGCGCTGAGGAAGACAAGGCCGGCGGCGAGCCCGTAGTGATCATCAGTGACGCGCTGTGGCAGCGCCGCTTC
GCCCAAGACCGCGCCGTGATCGGCAAGACGATGACGCTGGATTCGCGCGACTACACTGTAATCGGCGTGCTGCCGCCCGA
TTTCCGCTGGGCATTCCTCGGTCCGGCGATCGACATCTTCGCGCCGCGCGTCTTCGAAATGAATTCGCTCTCGCCCGGAA
TGGCCCAATCCGGCGTGGGCTTCCTGAACTTCGTGGCGCGCCTGGCGCCAGGCGTTGGAGTGGCCGGGGCACAGCAGGAG
ATGGACGCGCTGGCCGCTCAATACCGTGCGGAAAACCCCAAGCTGCCCGACACCGACCCGCAGCAGATCGTGCACGTCGG
CAACCTGCGCGACGAGATGGTTTCCTCGGTGCGGATCGCCGTGCTCGTCCTCTTCGCAGCCGTGTCGCTGGTGCTGCTGA
TCGCCTGCGCCAACGTGGCGAGCCTGCTGCTATCCCGCGCACTCGGGCGCAAACGCGAGATCGCGGTGCGCACCGCCATC
GGCGCCACCCGCGGCGAACTGATCCGGCAATTGCTCACGGAAAGCCTGCTGCTCGCCTTGTTGGGCGGCGTGATCGGCGC
GCTCTTGAGCTCGTGGGGCACGCACGCGTTGGCGGCTCTGGCACAGGGCACACTGCCGCGTGCATCGGAGATTCACACCG
ATGGCGCGGTGCTCGCCTTCACGCTCGGACTCTCCGTATTCGCAGGCTTCGTGTTCGGTCTGATTCCGGCGCTGCAGGTG
TCGCGGCCCGACTTGAATTCCGTGCTGCGCAGCGAAGGCCGCGGATCCACCAGCGGACGCCGGCACAACGCACTCCGCAA
TTTGCTGGTCGTCTCGCAGGTCGGCCTATCCACGGTGCTGTTGATCGGCGCGGGCCTGCTGGTGCGCAACTTCGTCCAAC
TCAGCAGCACAAGTCCGGGCTTCGACCAGCGCCGCATGCTAACGATGGCGATCACCCTCCCCTCGTCACGCTATCCGGAT
AGCCCGCGCCGCGTCGCCTTCTTCGACGAACTCCTTCGCCAGGTACGCGCGCTGCCGGGCGTGGCCGCAGCCGCGGGTTC
GACCGCGCTGCCGGTGAATCCCACGCGCTTCTCGATGGCCTTGCCCGATGGACAACCGATGGTCCCCCTGGCCGAGCGCC
CAATCTTCAACCTGGCGCAAATCACGCCCGGGTACGCGGCGGCGATGCGGATTCCTATCGTCGGCGGCCGCGAATTCACG
GAACACGATGACGCGAAATCGCCGCGCGTAGTGATGATCAACCAGACGCTGGCACGGCGCTACTGGCCCAACGAAAGCGC
CGTGGGAAAACGGATCCTGGTGGGCCGCGCGACCGCGACATCGGAGATCGTGGGGGTGCTGGGAGACGTGCCCAATCTCG
CCGTAGGCACGGATACGCAGCCGGAGTTCTATCTCGCGTTCGCACAGACGCCCTCGGCGACACAGAACCTGTTGGTACGC
ACGCTCGGCGACCCGAAGGGCTTGGTATCGGCAGTGCGCGCCCGCGTGCTCGCGCTCGATCGCGATCAGCCAGTCACGGG
AATCCAGAGCATGGAGGAAGTGCTCGAGAAAGGCGCGGCGCAACCGCGCTTCACCACCTACCTGCTCGGCGGACTGGCGG
GCACGGCGCTGCTGCTCGCGATCGTCGGCATCTATGGCGTGATCGCGTACTCCGTGGCCGAACGCACGCAGGAGATGGGA
ATCCGGATCGCGCTCGGCGCGGACGGAGGCGATATCCTGCGCCTCGTGATGCGCCACGGCATGGCGCTGGCAGCGGCCGG
AATCGCGATCGGTTTGGCCGCCGCGCTGGCCTTGACCAGGCTGATGGCGACCTTGCTCTATCGCGTCAGCGTGACCGACC
TCGCGACATTTGTCGCGGGCCCGGGCTCATTCCTCGCGATCGCCGCGCTGGCAAGCTACTTGCCTGCCCGCCGCGCAATG
CGCGTGGACCCGGTGATCGCGCTGCGCTCGGAGTGA

Upstream 100 bases:

>100_bases
GCTCCGGCGAAGGGCCAGCAATTAACCCCTCCGGTGCGGATTGTGCGCATCATTCGCAAACCGGCATAACGTTGTAGCGG
GAAGGCGCGTCTATCTGCCT

Downstream 100 bases:

>100_bases
GCCCGATCGCTTCGTCGCATGCCTGCGCCAATCCGAGCCGTGACCGTCAGGGAGCGGTTGCTAATTTTGGTTCGCCCTAC
CAAACGAACGGTATGAGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MSTVLQNARFGLRVFRRAPGFAAVAVLTLAVGIGANTSIFSVANALLLRPLAYEKPDRLVLINSHRKSANLSQGPLSFTR
FEEVDQRSRSFTGVGAFTSEVFNLTGNGDPEQILSARVSWKFFPVLGVSPALGRSFRAEEDKAGGEPVVIISDALWQRRF
AQDRAVIGKTMTLDSRDYTVIGVLPPDFRWAFLGPAIDIFAPRVFEMNSLSPGMAQSGVGFLNFVARLAPGVGVAGAQQE
MDALAAQYRAENPKLPDTDPQQIVHVGNLRDEMVSSVRIAVLVLFAAVSLVLLIACANVASLLLSRALGRKREIAVRTAI
GATRGELIRQLLTESLLLALLGGVIGALLSSWGTHALAALAQGTLPRASEIHTDGAVLAFTLGLSVFAGFVFGLIPALQV
SRPDLNSVLRSEGRGSTSGRRHNALRNLLVVSQVGLSTVLLIGAGLLVRNFVQLSSTSPGFDQRRMLTMAITLPSSRYPD
SPRRVAFFDELLRQVRALPGVAAAAGSTALPVNPTRFSMALPDGQPMVPLAERPIFNLAQITPGYAAAMRIPIVGGREFT
EHDDAKSPRVVMINQTLARRYWPNESAVGKRILVGRATATSEIVGVLGDVPNLAVGTDTQPEFYLAFAQTPSATQNLLVR
TLGDPKGLVSAVRARVLALDRDQPVTGIQSMEEVLEKGAAQPRFTTYLLGGLAGTALLLAIVGIYGVIAYSVAERTQEMG
IRIALGADGGDILRLVMRHGMALAAAGIAIGLAAALALTRLMATLLYRVSVTDLATFVAGPGSFLAIAALASYLPARRAM
RVDPVIALRSE

Sequences:

>Translated_811_residues
MSTVLQNARFGLRVFRRAPGFAAVAVLTLAVGIGANTSIFSVANALLLRPLAYEKPDRLVLINSHRKSANLSQGPLSFTR
FEEVDQRSRSFTGVGAFTSEVFNLTGNGDPEQILSARVSWKFFPVLGVSPALGRSFRAEEDKAGGEPVVIISDALWQRRF
AQDRAVIGKTMTLDSRDYTVIGVLPPDFRWAFLGPAIDIFAPRVFEMNSLSPGMAQSGVGFLNFVARLAPGVGVAGAQQE
MDALAAQYRAENPKLPDTDPQQIVHVGNLRDEMVSSVRIAVLVLFAAVSLVLLIACANVASLLLSRALGRKREIAVRTAI
GATRGELIRQLLTESLLLALLGGVIGALLSSWGTHALAALAQGTLPRASEIHTDGAVLAFTLGLSVFAGFVFGLIPALQV
SRPDLNSVLRSEGRGSTSGRRHNALRNLLVVSQVGLSTVLLIGAGLLVRNFVQLSSTSPGFDQRRMLTMAITLPSSRYPD
SPRRVAFFDELLRQVRALPGVAAAAGSTALPVNPTRFSMALPDGQPMVPLAERPIFNLAQITPGYAAAMRIPIVGGREFT
EHDDAKSPRVVMINQTLARRYWPNESAVGKRILVGRATATSEIVGVLGDVPNLAVGTDTQPEFYLAFAQTPSATQNLLVR
TLGDPKGLVSAVRARVLALDRDQPVTGIQSMEEVLEKGAAQPRFTTYLLGGLAGTALLLAIVGIYGVIAYSVAERTQEMG
IRIALGADGGDILRLVMRHGMALAAAGIAIGLAAALALTRLMATLLYRVSVTDLATFVAGPGSFLAIAALASYLPARRAM
RVDPVIALRSE
>Mature_810_residues
STVLQNARFGLRVFRRAPGFAAVAVLTLAVGIGANTSIFSVANALLLRPLAYEKPDRLVLINSHRKSANLSQGPLSFTRF
EEVDQRSRSFTGVGAFTSEVFNLTGNGDPEQILSARVSWKFFPVLGVSPALGRSFRAEEDKAGGEPVVIISDALWQRRFA
QDRAVIGKTMTLDSRDYTVIGVLPPDFRWAFLGPAIDIFAPRVFEMNSLSPGMAQSGVGFLNFVARLAPGVGVAGAQQEM
DALAAQYRAENPKLPDTDPQQIVHVGNLRDEMVSSVRIAVLVLFAAVSLVLLIACANVASLLLSRALGRKREIAVRTAIG
ATRGELIRQLLTESLLLALLGGVIGALLSSWGTHALAALAQGTLPRASEIHTDGAVLAFTLGLSVFAGFVFGLIPALQVS
RPDLNSVLRSEGRGSTSGRRHNALRNLLVVSQVGLSTVLLIGAGLLVRNFVQLSSTSPGFDQRRMLTMAITLPSSRYPDS
PRRVAFFDELLRQVRALPGVAAAAGSTALPVNPTRFSMALPDGQPMVPLAERPIFNLAQITPGYAAAMRIPIVGGREFTE
HDDAKSPRVVMINQTLARRYWPNESAVGKRILVGRATATSEIVGVLGDVPNLAVGTDTQPEFYLAFAQTPSATQNLLVRT
LGDPKGLVSAVRARVLALDRDQPVTGIQSMEEVLEKGAAQPRFTTYLLGGLAGTALLLAIVGIYGVIAYSVAERTQEMGI
RIALGADGGDILRLVMRHGMALAAAGIAIGLAAALALTRLMATLLYRVSVTDLATFVAGPGSFLAIAALASYLPARRAMR
VDPVIALRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=269, Percent_Identity=26.0223048327138, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 86312; Mature: 86180

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLQNARFGLRVFRRAPGFAAVAVLTLAVGIGANTSIFSVANALLLRPLAYEKPDRLV
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEE
LINSHRKSANLSQGPLSFTRFEEVDQRSRSFTGVGAFTSEVFNLTGNGDPEQILSARVSW
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCE
KFFPVLGVSPALGRSFRAEEDKAGGEPVVIISDALWQRRFAQDRAVIGKTMTLDSRDYTV
EEEECCCCCHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCEEEECCCCEEE
IGVLPPDFRWAFLGPAIDIFAPRVFEMNSLSPGMAQSGVGFLNFVARLAPGVGVAGAQQE
EEECCCCCCEEECCCHHHHHCCCCEECCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCHHH
MDALAAQYRAENPKLPDTDPQQIVHVGNLRDEMVSSVRIAVLVLFAAVSLVLLIACANVA
HHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLSRALGRKREIAVRTAIGATRGELIRQLLTESLLLALLGGVIGALLSSWGTHALAAL
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AQGTLPRASEIHTDGAVLAFTLGLSVFAGFVFGLIPALQVSRPDLNSVLRSEGRGSTSGR
HHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
RHNALRNLLVVSQVGLSTVLLIGAGLLVRNFVQLSSTSPGFDQRRMLTMAITLPSSRYPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCCC
SPRRVAFFDELLRQVRALPGVAAAAGSTALPVNPTRFSMALPDGQPMVPLAERPIFNLAQ
CCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHH
ITPGYAAAMRIPIVGGREFTEHDDAKSPRVVMINQTLARRYWPNESAVGKRILVGRATAT
CCCCHHHHEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCHHCCCEEEEECCHHH
SEIVGVLGDVPNLAVGTDTQPEFYLAFAQTPSATQNLLVRTLGDPKGLVSAVRARVLALD
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RDQPVTGIQSMEEVLEKGAAQPRFTTYLLGGLAGTALLLAIVGIYGVIAYSVAERTQEMG
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRIALGADGGDILRLVMRHGMALAAAGIAIGLAAALALTRLMATLLYRVSVTDLATFVAG
EEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGSFLAIAALASYLPARRAMRVDPVIALRSE
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
>Mature Secondary Structure 
STVLQNARFGLRVFRRAPGFAAVAVLTLAVGIGANTSIFSVANALLLRPLAYEKPDRLV
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEE
LINSHRKSANLSQGPLSFTRFEEVDQRSRSFTGVGAFTSEVFNLTGNGDPEQILSARVSW
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCE
KFFPVLGVSPALGRSFRAEEDKAGGEPVVIISDALWQRRFAQDRAVIGKTMTLDSRDYTV
EEEECCCCCHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCEEEECCCCEEE
IGVLPPDFRWAFLGPAIDIFAPRVFEMNSLSPGMAQSGVGFLNFVARLAPGVGVAGAQQE
EEECCCCCCEEECCCHHHHHCCCCEECCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCHHH
MDALAAQYRAENPKLPDTDPQQIVHVGNLRDEMVSSVRIAVLVLFAAVSLVLLIACANVA
HHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLLSRALGRKREIAVRTAIGATRGELIRQLLTESLLLALLGGVIGALLSSWGTHALAAL
HHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AQGTLPRASEIHTDGAVLAFTLGLSVFAGFVFGLIPALQVSRPDLNSVLRSEGRGSTSGR
HHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCH
RHNALRNLLVVSQVGLSTVLLIGAGLLVRNFVQLSSTSPGFDQRRMLTMAITLPSSRYPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEECCCCCCCC
SPRRVAFFDELLRQVRALPGVAAAAGSTALPVNPTRFSMALPDGQPMVPLAERPIFNLAQ
CCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHH
ITPGYAAAMRIPIVGGREFTEHDDAKSPRVVMINQTLARRYWPNESAVGKRILVGRATAT
CCCCHHHHEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCHHCCCEEEEECCHHH
SEIVGVLGDVPNLAVGTDTQPEFYLAFAQTPSATQNLLVRTLGDPKGLVSAVRARVLALD
HHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RDQPVTGIQSMEEVLEKGAAQPRFTTYLLGGLAGTALLLAIVGIYGVIAYSVAERTQEMG
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IRIALGADGGDILRLVMRHGMALAAAGIAIGLAAALALTRLMATLLYRVSVTDLATFVAG
EEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGSFLAIAALASYLPARRAMRVDPVIALRSE
CCHHHHHHHHHHHHHHHHCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA