Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 116619860

GI number: 116619860

Start: 920979

End: 922016

Strand: Direct

Name: hrcA [H]

Synonym: Acid_0732

Alternate gene names: 116619860

Gene position: 920979-922016 (Clockwise)

Preceding gene: 116619854

Following gene: 116619861

Centisome position: 9.24

GC content: 59.73

Gene sequence:

>1038_bases
ATGAGAACGGACGCGCCGCTCAACTTCAGATACCAGGAGATCCTGACTTCGATCGTCCGGGCGTACATCGACACCGGGGA
ACCGGTGGGATCCCGCACGATTTCGAAGCTGCGGCAGAATACCCTCAGTCCGGCATCGATCCGTAACGTCATGGCAGATC
TGGCCGATGAGGGCTACCTCTCGCAGCCGCACACCTCGGCCGGACGTATTCCCACGGAAAAAGCATTTCGATTCTATGTA
AGGTCGTTGACAGCCGGCCGTTTTGGAACCGGGGAATCGGAACGCATCAACAATGAATTTCGCGGATTGGACACCGTCGG
GCAGCGTGTGGAACGCTCCAGTTACATCCTGGTGGAGCTCACCAAGAATGTCGGCATCGCCGCTGCCATTCCCGAGCTGG
CGCAGGAACTCGATCAGATTCAACTGGTCCCGCTCTCCGACCGCCGCGTCCTGATGGTTCTGGTGACGCGCGACCACATG
GTCCGCAACCGCGTGGTCATGCTCGATGAGCCGACCTCGCCCGAAGAACTCATCTCCATCTGTAATTTCGTGAACCGAAA
TTTCAGCGGCTGGCAGCTGGGTAAGGCCCGGCGCGAGCTTCTCAACCGCATCGCGCAAGAGCGCGAGATGTACCACGCGG
TGCTTCACAAGCTGCAGATGTTGTACCAGAAGGGCTTGCTCGAAATCGATACTTCACCCGAAGTGCACATGGAAGGCGCG
AGCAACCTGCTCGGGCTGGACCTGCACCTCACCCGTGAACGCATGCGCGAACTGTTCCACGCGCTGGAAGAAAAGCAGCG
CGTGATCGAACTGCTGGACCGCTTTCTGGAACAGCCTCCAGGGGAACTTGCCGTGCATGTAGGTTTAGAGAAGGCGCACC
CGGCCATGAAAGATCTTGCCCTGATCGGCATGACGATTCGCATGGCCAGCGGCCTGCCGGCGAAGGTGGCCGTGCTTGGC
CCCATGCGCATGAATTACGAGCGCGTGATGGCGGCCGTGCTGCAAACCAGCCGGGCGCTCGGGAGCGCACAGTTTTAG

Upstream 100 bases:

>100_bases
TTTAGAGCGTATGCCGCTCGGCTGCATCCTGGCCAATTTGACCCTTGGCCGTATCCCCATCTAAAATAGTGTTTAGAGTA
GTGTGGGTACTCAAGGGTTT

Downstream 100 bases:

>100_bases
CGCCGCCGCGCGCGGCGCAGGAAAGCCAATTAAGGAAGTGAACACCCTGAACCCTCAAGAAAATACTCCGGAAATGGCGG
AAGCTGAAGGCGGCGGGGAA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRTDAPLNFRYQEILTSIVRAYIDTGEPVGSRTISKLRQNTLSPASIRNVMADLADEGYLSQPHTSAGRIPTEKAFRFYV
RSLTAGRFGTGESERINNEFRGLDTVGQRVERSSYILVELTKNVGIAAAIPELAQELDQIQLVPLSDRRVLMVLVTRDHM
VRNRVVMLDEPTSPEELISICNFVNRNFSGWQLGKARRELLNRIAQEREMYHAVLHKLQMLYQKGLLEIDTSPEVHMEGA
SNLLGLDLHLTRERMRELFHALEEKQRVIELLDRFLEQPPGELAVHVGLEKAHPAMKDLALIGMTIRMASGLPAKVAVLG
PMRMNYERVMAAVLQTSRALGSAQF

Sequences:

>Translated_345_residues
MRTDAPLNFRYQEILTSIVRAYIDTGEPVGSRTISKLRQNTLSPASIRNVMADLADEGYLSQPHTSAGRIPTEKAFRFYV
RSLTAGRFGTGESERINNEFRGLDTVGQRVERSSYILVELTKNVGIAAAIPELAQELDQIQLVPLSDRRVLMVLVTRDHM
VRNRVVMLDEPTSPEELISICNFVNRNFSGWQLGKARRELLNRIAQEREMYHAVLHKLQMLYQKGLLEIDTSPEVHMEGA
SNLLGLDLHLTRERMRELFHALEEKQRVIELLDRFLEQPPGELAVHVGLEKAHPAMKDLALIGMTIRMASGLPAKVAVLG
PMRMNYERVMAAVLQTSRALGSAQF
>Mature_345_residues
MRTDAPLNFRYQEILTSIVRAYIDTGEPVGSRTISKLRQNTLSPASIRNVMADLADEGYLSQPHTSAGRIPTEKAFRFYV
RSLTAGRFGTGESERINNEFRGLDTVGQRVERSSYILVELTKNVGIAAAIPELAQELDQIQLVPLSDRRVLMVLVTRDHM
VRNRVVMLDEPTSPEELISICNFVNRNFSGWQLGKARRELLNRIAQEREMYHAVLHKLQMLYQKGLLEIDTSPEVHMEGA
SNLLGLDLHLTRERMRELFHALEEKQRVIELLDRFLEQPPGELAVHVGLEKAHPAMKDLALIGMTIRMASGLPAKVAVLG
PMRMNYERVMAAVLQTSRALGSAQF

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38969; Mature: 38969

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTDAPLNFRYQEILTSIVRAYIDTGEPVGSRTISKLRQNTLSPASIRNVMADLADEGYL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
SQPHTSAGRIPTEKAFRFYVRSLTAGRFGTGESERINNEFRGLDTVGQRVERSSYILVEL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEE
TKNVGIAAAIPELAQELDQIQLVPLSDRRVLMVLVTRDHMVRNRVVMLDEPTSPEELISI
ECCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEHHHHHHCCEEEEECCCCHHHHHHH
CNFVNRNFSGWQLGKARRELLNRIAQEREMYHAVLHKLQMLYQKGLLEIDTSPEVHMEGA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCC
SNLLGLDLHLTRERMRELFHALEEKQRVIELLDRFLEQPPGELAVHVGLEKAHPAMKDLA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHH
LIGMTIRMASGLPAKVAVLGPMRMNYERVMAAVLQTSRALGSAQF
HHHHHHHHHCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRTDAPLNFRYQEILTSIVRAYIDTGEPVGSRTISKLRQNTLSPASIRNVMADLADEGYL
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
SQPHTSAGRIPTEKAFRFYVRSLTAGRFGTGESERINNEFRGLDTVGQRVERSSYILVEL
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEE
TKNVGIAAAIPELAQELDQIQLVPLSDRRVLMVLVTRDHMVRNRVVMLDEPTSPEELISI
ECCCCHHHHHHHHHHHHHHEEEEECCCCCEEEEEEEHHHHHHCCEEEEECCCCHHHHHHH
CNFVNRNFSGWQLGKARRELLNRIAQEREMYHAVLHKLQMLYQKGLLEIDTSPEVHMEGA
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEECCC
SNLLGLDLHLTRERMRELFHALEEKQRVIELLDRFLEQPPGELAVHVGLEKAHPAMKDLA
CCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHCHHHHHHH
LIGMTIRMASGLPAKVAVLGPMRMNYERVMAAVLQTSRALGSAQF
HHHHHHHHHCCCCCEEEEECCHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA