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The map label for this gene is ykcC [H]

Identifier: 116619426

GI number: 116619426

Start: 384466

End: 385359

Strand: Direct

Name: ykcC [H]

Synonym: Acid_0285

Alternate gene names: 116619426

Gene position: 384466-385359 (Clockwise)

Preceding gene: 116619419

Following gene: 116619427

Centisome position: 3.86

GC content: 57.94

Gene sequence:

>894_bases
ATGTTCTCTGTATTTCATCCGGCAAGATACAATTATCGAACAAGACAGCGTCGCCAGTGCGCCACGATACTTTGTTGCGC
CCCAGGATGCCTGTTATTATTGCCCGGAGGAGTCTTTGCCGTGAAGTTGTCGCTGGTTATGCCGGCCCGGAACGAAGAAG
GTTGCATTGCCACGACGCTGGGGCGGTTTACCAGCGTGCTGACGGCCAACGCGCTGGATTTCGAGATCGTCGTGGTGGAC
GACGGCAGCACGGATGCCACTGCGGACCTGCTCGCTGCCATCAGCGCGCGCCATCCCCAGGTGGTGCCGGTGACGAACGA
TGGGCGCCATGGATTCGGAATGGCAATCCGGTATGGACTTTCGCGGATCACGGGCGATGCGGTCGCGATTGTGATGGCGG
ACGGCTCCGACAGTCCAGAAGACCTCCTGAAATATTACACCAAGCTGCTGCAGGGCTACGATTGCGTGTTCGGCTCGCGC
TTCATCAAAGGCGGCTGCGTGGTGGACTATCCGCGCCACAAGCTGCTGTTGAACCGCATGGCGAACGCCTTCATCCGAGT
GCTTTTCGGCCTTAGCTTTAACGACATTACCAACGCGTTCAAATGCTACCGGAAGGAAGTGATCACCGGTATGCAGCCCC
TGATTTCACCGCATTTCAACCTGACAGTGGAGATGCCGCTGAAGGCCCTGGTACGAGGATATTCGTTCGCGGTGGTGCCG
ATCACCTGGACCAATCGCGCGGCCGGGGTCTCGAAGCTGAAGATCAAAGAGATGGGCAGCCGCTACCTGTTCATCGTGCT
GTACCTCTGGCTGGAAAAGCACCTGTCCCGCGGCGATTATCACCGCAAGGTGATTGCTCCGGCGGACGAGAGGACCACTC
ACATCAATGCATGA

Upstream 100 bases:

>100_bases
ATCGGCGCGGTACCGCATTGTCCGGTTTTGATTTGGCCGTTGCCGATCATCGAGACCGAGAAAAGCAGGAAGGCCGCCTT
CATCGGGTTTGTTCTCCGGG

Downstream 100 bases:

>100_bases
AACCGTTCTGATCACAGGGGGCGCCGGTTTTGTCGGCTCCGCCCTGGCGATCGCGATCCGGCGCGCTCATCCCGCCACCA
AGGTCATCGCCTTCGATAAC

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MFSVFHPARYNYRTRQRRQCATILCCAPGCLLLLPGGVFAVKLSLVMPARNEEGCIATTLGRFTSVLTANALDFEIVVVD
DGSTDATADLLAAISARHPQVVPVTNDGRHGFGMAIRYGLSRITGDAVAIVMADGSDSPEDLLKYYTKLLQGYDCVFGSR
FIKGGCVVDYPRHKLLLNRMANAFIRVLFGLSFNDITNAFKCYRKEVITGMQPLISPHFNLTVEMPLKALVRGYSFAVVP
ITWTNRAAGVSKLKIKEMGSRYLFIVLYLWLEKHLSRGDYHRKVIAPADERTTHINA

Sequences:

>Translated_297_residues
MFSVFHPARYNYRTRQRRQCATILCCAPGCLLLLPGGVFAVKLSLVMPARNEEGCIATTLGRFTSVLTANALDFEIVVVD
DGSTDATADLLAAISARHPQVVPVTNDGRHGFGMAIRYGLSRITGDAVAIVMADGSDSPEDLLKYYTKLLQGYDCVFGSR
FIKGGCVVDYPRHKLLLNRMANAFIRVLFGLSFNDITNAFKCYRKEVITGMQPLISPHFNLTVEMPLKALVRGYSFAVVP
ITWTNRAAGVSKLKIKEMGSRYLFIVLYLWLEKHLSRGDYHRKVIAPADERTTHINA
>Mature_297_residues
MFSVFHPARYNYRTRQRRQCATILCCAPGCLLLLPGGVFAVKLSLVMPARNEEGCIATTLGRFTSVLTANALDFEIVVVD
DGSTDATADLLAAISARHPQVVPVTNDGRHGFGMAIRYGLSRITGDAVAIVMADGSDSPEDLLKYYTKLLQGYDCVFGSR
FIKGGCVVDYPRHKLLLNRMANAFIRVLFGLSFNDITNAFKCYRKEVITGMQPLISPHFNLTVEMPLKALVRGYSFAVVP
ITWTNRAAGVSKLKIKEMGSRYLFIVLYLWLEKHLSRGDYHRKVIAPADERTTHINA

Specific function: Unknown

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=223, Percent_Identity=26.9058295964126, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1788588, Length=212, Percent_Identity=25.9433962264151, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71999402, Length=240, Percent_Identity=25.4166666666667, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24585265, Length=222, Percent_Identity=31.0810810810811, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 33001; Mature: 33001

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVFHPARYNYRTRQRRQCATILCCAPGCLLLLPGGVFAVKLSLVMPARNEEGCIATTL
CCCCCCCCCCCCHHHHHHHHHEEEEECCCEEEEECCCEEEEEEEEEECCCCCCCCCHHHH
GRFTSVLTANALDFEIVVVDDGSTDATADLLAAISARHPQVVPVTNDGRHGFGMAIRYGL
HHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
SRITGDAVAIVMADGSDSPEDLLKYYTKLLQGYDCVFGSRFIKGGCVVDYPRHKLLLNRM
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCHHHHHHHHH
ANAFIRVLFGLSFNDITNAFKCYRKEVITGMQPLISPHFNLTVEMPLKALVRGYSFAVVP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEECCHHHHHCCCCEEEEE
ITWTNRAAGVSKLKIKEMGSRYLFIVLYLWLEKHLSRGDYHRKVIAPADERTTHINA
EEECCCCCCCHHEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MFSVFHPARYNYRTRQRRQCATILCCAPGCLLLLPGGVFAVKLSLVMPARNEEGCIATTL
CCCCCCCCCCCCHHHHHHHHHEEEEECCCEEEEECCCEEEEEEEEEECCCCCCCCCHHHH
GRFTSVLTANALDFEIVVVDDGSTDATADLLAAISARHPQVVPVTNDGRHGFGMAIRYGL
HHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
SRITGDAVAIVMADGSDSPEDLLKYYTKLLQGYDCVFGSRFIKGGCVVDYPRHKLLLNRM
HHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCHHHHHHHHH
ANAFIRVLFGLSFNDITNAFKCYRKEVITGMQPLISPHFNLTVEMPLKALVRGYSFAVVP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCEEEECCHHHHHCCCCEEEEE
ITWTNRAAGVSKLKIKEMGSRYLFIVLYLWLEKHLSRGDYHRKVIAPADERTTHINA
EEECCCCCCCHHEEHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]