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The map label for this gene is nuoG2 [H]

Identifier: 116619258

GI number: 116619258

Start: 152189

End: 154474

Strand: Direct

Name: nuoG2 [H]

Synonym: Acid_0114

Alternate gene names: 116619258

Gene position: 152189-154474 (Clockwise)

Preceding gene: 116619257

Following gene: 116619259

Centisome position: 1.53

GC content: 63.21

Gene sequence:

>2286_bases
ATGGCTGATCTGGTAAATCTGACAATCGACGGGAGAGCGGTGCAGGTGCCGCCGCAGACGCTGGTGATCGACGCCGCCAA
AACGGTCGGCATCGAGATCCCCGCGTTCTGCTATTACGAAGGCCTCACCCTGCAGGCCGCCTGCCGCATGTGCCTGGTGG
AAGTGGAAAAAATGCCGAAGATGATGACGGCATGCACGCTTCCCGTGGCCGAAGGCATGATCGTGCGCACGGAGACCGAG
CAGGTCAAACAGGCGCGCAAATACACGCTCGAATTCCTGCTCACCAATCATCCGCTGGATTGCCCGGTCTGCGATAAGGG
CGGCGAATGCGAGCTGCAGGACATGGTCTTCCGCTACGGCGCGGGTGAAAGCCGGTACACGGAAGAAAAGGTGCACACGC
CCGAGAAGCAGTTCTCCCCGGTGGTCTTCTTCGATGCGCCGCGCTGCATCCTCTGCTTCCGCTGCGTCCGCATCTGCAAC
GAAGGCCTCGGCGTGGGCGCGCTCGGCGTCATCAACCGCGGCGTGGTCTCGGAGATCGCCCCGAACGTGGGCGATCACCT
GGAATGCGACGAATGCGGCGCCTGCATCGATATCTGCCCGGTGGGCGCGCTCACCAGCGGCATCTACCGCTACCAGACCC
GCCCGTGGGAAATGGCGCATGTCGGCACCATCTGCACTCACTGCGGCGACGGCTGCAAGACCACCCTGGGAACGCGCAAC
GACGAAATCATTCGCGGCAACAACCGCGACCGCAGCGGCATCAACGGCGAGTTCCTCTGCATCAAGGGCCGCTACGCGTT
CGATTTCTACAACCATCCCGAGCGCCTGCAGGCACCCATGCTGCGCGTAAACGGCAAACTGGAAGAGGTCTCCTGGGCGC
GGGCCCTCGAGGCTGTGGGCAAGAAATTCAAGCAGACCGCGGAAGCCGGCGGCAGCTTCGGCGTCATCGGCAGCAACCAC
ACCAGCAACGAAGAGAACTTCTACCTGCAGAAGTTCGCGCGCCAGGTGCTGAAGACCAATAACATCGATCATCACCGCAC
CGGGGACGTAGTTACGCTGCTCGATTCGCTGAGCGGCAAGACCGCGCAACTGGCCACGGTAGCCGATCTCTACGACCGCA
AGGCCGTACTGGTGCTTGGCGCCGATCTCGCGCTCGAACATCCTCTGCTCAGCTTCCAGATTCGCGCCAATTACCGGCAT
CATCAGGCGCATGTCTACGCCATTACGCCGGGTCCGGTGCGGGAGGACAAGTACTCTGTCGCCAGCATTCGTGTGGGCAA
GAGCGGCGCCGCGAAAGTCGGCGGCGATCTCGGCGTGGTGCCCGGCCGTGAAGTCGGCGCCACTTCAAGCGGTCCCGGAT
CGGCGCCGGTCGGCGGCCCCGGAGTCGTGCCCAATGCCGAAGCGGGCGCGCACTTCGAACCGGTTCACGGAGCTGGTAGC
GCCAACGGCAGCCCCTCCGGTTTCGTCCATCCGCACAATGTGACCGCGGTACCAGCGGATTATTTTGGCGCGCTCGAATC
GCTCCGCGACAAATTGAAGGCCGAGCCCGAACTGGTCGTGGTCTTCGATGATTCCTTCAAGGGCGACGATGTCCGAAAAC
TGGTGGAGTTCACGGAATCGCTTGGCATCCCGGTCAAGTTCGTCTGCCTGGTGGATTACGCCAACTCCCGCGGCGCGGCC
GATATGGGCCTCACGCCCGAGTTGCTGCCCGGCTACAAGCCCAGCGGGACGCCCGGACTGCATGTCGCCGAAATGATCGC
GAACGACCTGGACGTGGTTTGGGTGGTTGGGGCCAATCCGCTGAAGGGCGCGGTGAAGCGGAAGGCCGGATTCCTGGTAG
TGCAGGACATGTTCCTCACCGAGACCGCGCAGCAGGCCGACGTCGTCCTGCCCGCCGGGTCTGCCTACGAGAAGAACGGC
ACCGTCACCAATACCACCGGCGAAGTGCAGCAGCTCACGCGCGCCATCAACACCATGGGCGCCAAGCCGGATCTCGAAAT
CATGGGTTTCATCGCCCGCGAAATGGGCGTGGCCGCGCAGCTCGGCCCCTGGCTTCCGCAAGTGGTCTTTGAGGAAATTC
GCAAGAATGTGCGCGGCTACTCGCTGCCCATGCCGGTGATCGCCACCGGCGGCGCGGCCCAGACCATGCCGGTCAACGGG
CGCATTCCCGTGGAGAACCGGCCCGACCTGGTGCGGAGTGACCATAATGGGCTCTTCGCCTCCGGTACCCTTGGGCGGTA
TTCTAAGGTTCTGAACTCCGTTATAGAAAGTCGCTTGAGCCGCTAA

Upstream 100 bases:

>100_bases
CCAACCGGATGGTGACCGTGTAATGGGGACAGATTTGAGAACGCTCCCTTACGGTCGCGGCTCTGATAGGGGAGCGATCT
TTTTCTCAATAAAGGTTTGA

Downstream 100 bases:

>100_bases
ATGGAGCTACTCGACTCGTTTATCTTTATCAGCCTGGTGAAGGCGGCAGTTATTTTCGGCGTGCTGATGACCACGCTGGC
CTACCTGCAGTGGGTGGAGC

Product: NADH-quinone oxidoreductase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G 2; NDH-1 subunit G 2 [H]

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MADLVNLTIDGRAVQVPPQTLVIDAAKTVGIEIPAFCYYEGLTLQAACRMCLVEVEKMPKMMTACTLPVAEGMIVRTETE
QVKQARKYTLEFLLTNHPLDCPVCDKGGECELQDMVFRYGAGESRYTEEKVHTPEKQFSPVVFFDAPRCILCFRCVRICN
EGLGVGALGVINRGVVSEIAPNVGDHLECDECGACIDICPVGALTSGIYRYQTRPWEMAHVGTICTHCGDGCKTTLGTRN
DEIIRGNNRDRSGINGEFLCIKGRYAFDFYNHPERLQAPMLRVNGKLEEVSWARALEAVGKKFKQTAEAGGSFGVIGSNH
TSNEENFYLQKFARQVLKTNNIDHHRTGDVVTLLDSLSGKTAQLATVADLYDRKAVLVLGADLALEHPLLSFQIRANYRH
HQAHVYAITPGPVREDKYSVASIRVGKSGAAKVGGDLGVVPGREVGATSSGPGSAPVGGPGVVPNAEAGAHFEPVHGAGS
ANGSPSGFVHPHNVTAVPADYFGALESLRDKLKAEPELVVVFDDSFKGDDVRKLVEFTESLGIPVKFVCLVDYANSRGAA
DMGLTPELLPGYKPSGTPGLHVAEMIANDLDVVWVVGANPLKGAVKRKAGFLVVQDMFLTETAQQADVVLPAGSAYEKNG
TVTNTTGEVQQLTRAINTMGAKPDLEIMGFIAREMGVAAQLGPWLPQVVFEEIRKNVRGYSLPMPVIATGGAAQTMPVNG
RIPVENRPDLVRSDHNGLFASGTLGRYSKVLNSVIESRLSR

Sequences:

>Translated_761_residues
MADLVNLTIDGRAVQVPPQTLVIDAAKTVGIEIPAFCYYEGLTLQAACRMCLVEVEKMPKMMTACTLPVAEGMIVRTETE
QVKQARKYTLEFLLTNHPLDCPVCDKGGECELQDMVFRYGAGESRYTEEKVHTPEKQFSPVVFFDAPRCILCFRCVRICN
EGLGVGALGVINRGVVSEIAPNVGDHLECDECGACIDICPVGALTSGIYRYQTRPWEMAHVGTICTHCGDGCKTTLGTRN
DEIIRGNNRDRSGINGEFLCIKGRYAFDFYNHPERLQAPMLRVNGKLEEVSWARALEAVGKKFKQTAEAGGSFGVIGSNH
TSNEENFYLQKFARQVLKTNNIDHHRTGDVVTLLDSLSGKTAQLATVADLYDRKAVLVLGADLALEHPLLSFQIRANYRH
HQAHVYAITPGPVREDKYSVASIRVGKSGAAKVGGDLGVVPGREVGATSSGPGSAPVGGPGVVPNAEAGAHFEPVHGAGS
ANGSPSGFVHPHNVTAVPADYFGALESLRDKLKAEPELVVVFDDSFKGDDVRKLVEFTESLGIPVKFVCLVDYANSRGAA
DMGLTPELLPGYKPSGTPGLHVAEMIANDLDVVWVVGANPLKGAVKRKAGFLVVQDMFLTETAQQADVVLPAGSAYEKNG
TVTNTTGEVQQLTRAINTMGAKPDLEIMGFIAREMGVAAQLGPWLPQVVFEEIRKNVRGYSLPMPVIATGGAAQTMPVNG
RIPVENRPDLVRSDHNGLFASGTLGRYSKVLNSVIESRLSR
>Mature_760_residues
ADLVNLTIDGRAVQVPPQTLVIDAAKTVGIEIPAFCYYEGLTLQAACRMCLVEVEKMPKMMTACTLPVAEGMIVRTETEQ
VKQARKYTLEFLLTNHPLDCPVCDKGGECELQDMVFRYGAGESRYTEEKVHTPEKQFSPVVFFDAPRCILCFRCVRICNE
GLGVGALGVINRGVVSEIAPNVGDHLECDECGACIDICPVGALTSGIYRYQTRPWEMAHVGTICTHCGDGCKTTLGTRND
EIIRGNNRDRSGINGEFLCIKGRYAFDFYNHPERLQAPMLRVNGKLEEVSWARALEAVGKKFKQTAEAGGSFGVIGSNHT
SNEENFYLQKFARQVLKTNNIDHHRTGDVVTLLDSLSGKTAQLATVADLYDRKAVLVLGADLALEHPLLSFQIRANYRHH
QAHVYAITPGPVREDKYSVASIRVGKSGAAKVGGDLGVVPGREVGATSSGPGSAPVGGPGVVPNAEAGAHFEPVHGAGSA
NGSPSGFVHPHNVTAVPADYFGALESLRDKLKAEPELVVVFDDSFKGDDVRKLVEFTESLGIPVKFVCLVDYANSRGAAD
MGLTPELLPGYKPSGTPGLHVAEMIANDLDVVWVVGANPLKGAVKRKAGFLVVQDMFLTETAQQADVVLPAGSAYEKNGT
VTNTTGEVQQLTRAINTMGAKPDLEIMGFIAREMGVAAQLGPWLPQVVFEEIRKNVRGYSLPMPVIATGGAAQTMPVNGR
IPVENRPDLVRSDHNGLFASGTLGRYSKVLNSVIESRLSR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG3383

COG function: function code R; Uncharacterized anaerobic dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=408, Percent_Identity=35.0490196078431, Blast_Score=251, Evalue=2e-66,
Organism=Escherichia coli, GI145693161, Length=402, Percent_Identity=28.6069651741293, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI3868721, Length=535, Percent_Identity=25.2336448598131, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1788534, Length=183, Percent_Identity=26.775956284153, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565758, Length=408, Percent_Identity=33.578431372549, Blast_Score=233, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI32566231, Length=408, Percent_Identity=33.578431372549, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI193209088, Length=244, Percent_Identity=40.5737704918033, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24640559, Length=602, Percent_Identity=31.5614617940199, Blast_Score=254, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24640557, Length=602, Percent_Identity=31.5614617940199, Blast_Score=254, Evalue=2e-67,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR000283
- InterPro:   IPR019574 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 82038; Mature: 81907

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLVNLTIDGRAVQVPPQTLVIDAAKTVGIEIPAFCYYEGLTLQAACRMCLVEVEKMPK
CCCEEEEEECCEEEECCCCEEEEECHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
MMTACTLPVAEGMIVRTETEQVKQARKYTLEFLLTNHPLDCPVCDKGGECELQDMVFRYG
HHHHHCCHHHCCEEEECCHHHHHHHHHHEEHHEEECCCCCCCCCCCCCCCCHHHHHHHHC
AGESRYTEEKVHTPEKQFSPVVFFDAPRCILCFRCVRICNEGLGVGALGVINRGVVSEIA
CCCCCCCHHHHCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
PNVGDHLECDECGACIDICPVGALTSGIYRYQTRPWEMAHVGTICTHCGDGCKTTLGTRN
CCCCCCCCHHHCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DEIIRGNNRDRSGINGEFLCIKGRYAFDFYNHPERLQAPMLRVNGKLEEVSWARALEAVG
CCEEECCCCCCCCCCCCEEEEECCEEEECCCCHHHHHCCHHHHCCCHHHHHHHHHHHHHH
KKFKQTAEAGGSFGVIGSNHTSNEENFYLQKFARQVLKTNNIDHHRTGDVVTLLDSLSGK
HHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TAQLATVADLYDRKAVLVLGADLALEHPLLSFQIRANYRHHQAHVYAITPGPVREDKYSV
CCHHHHHHHHHCCCEEEEEECCHHHCCCCEEEEEEECCEECEEEEEEECCCCCCCCCEEE
ASIRVGKSGAAKVGGDLGVVPGREVGATSSGPGSAPVGGPGVVPNAEAGAHFEPVHGAGS
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANGSPSGFVHPHNVTAVPADYFGALESLRDKLKAEPELVVVFDDSFKGDDVRKLVEFTES
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHH
LGIPVKFVCLVDYANSRGAADMGLTPELLPGYKPSGTPGLHVAEMIANDLDVVWVVGANP
CCCCEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCC
LKGAVKRKAGFLVVQDMFLTETAQQADVVLPAGSAYEKNGTVTNTTGEVQQLTRAINTMG
HHHHHHHHCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHCC
AKPDLEIMGFIAREMGVAAQLGPWLPQVVFEEIRKNVRGYSLPMPVIATGGAAQTMPVNG
CCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCC
RIPVENRPDLVRSDHNGLFASGTLGRYSKVLNSVIESRLSR
CCCCCCCCCHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADLVNLTIDGRAVQVPPQTLVIDAAKTVGIEIPAFCYYEGLTLQAACRMCLVEVEKMPK
CCEEEEEECCEEEECCCCEEEEECHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
MMTACTLPVAEGMIVRTETEQVKQARKYTLEFLLTNHPLDCPVCDKGGECELQDMVFRYG
HHHHHCCHHHCCEEEECCHHHHHHHHHHEEHHEEECCCCCCCCCCCCCCCCHHHHHHHHC
AGESRYTEEKVHTPEKQFSPVVFFDAPRCILCFRCVRICNEGLGVGALGVINRGVVSEIA
CCCCCCCHHHHCCCHHHCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
PNVGDHLECDECGACIDICPVGALTSGIYRYQTRPWEMAHVGTICTHCGDGCKTTLGTRN
CCCCCCCCHHHCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DEIIRGNNRDRSGINGEFLCIKGRYAFDFYNHPERLQAPMLRVNGKLEEVSWARALEAVG
CCEEECCCCCCCCCCCCEEEEECCEEEECCCCHHHHHCCHHHHCCCHHHHHHHHHHHHHH
KKFKQTAEAGGSFGVIGSNHTSNEENFYLQKFARQVLKTNNIDHHRTGDVVTLLDSLSGK
HHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TAQLATVADLYDRKAVLVLGADLALEHPLLSFQIRANYRHHQAHVYAITPGPVREDKYSV
CCHHHHHHHHHCCCEEEEEECCHHHCCCCEEEEEEECCEECEEEEEEECCCCCCCCCEEE
ASIRVGKSGAAKVGGDLGVVPGREVGATSSGPGSAPVGGPGVVPNAEAGAHFEPVHGAGS
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANGSPSGFVHPHNVTAVPADYFGALESLRDKLKAEPELVVVFDDSFKGDDVRKLVEFTES
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHH
LGIPVKFVCLVDYANSRGAADMGLTPELLPGYKPSGTPGLHVAEMIANDLDVVWVVGANP
CCCCEEEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCC
LKGAVKRKAGFLVVQDMFLTETAQQADVVLPAGSAYEKNGTVTNTTGEVQQLTRAINTMG
HHHHHHHHCCEEEEEHHHHHHHHCCCCEEEECCCCCCCCCCEECCCHHHHHHHHHHHHCC
AKPDLEIMGFIAREMGVAAQLGPWLPQVVFEEIRKNVRGYSLPMPVIATGGAAQTMPVNG
CCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCC
RIPVENRPDLVRSDHNGLFASGTLGRYSKVLNSVIESRLSR
CCCCCCCCCHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]