Click here to switch to the map view.

The map label for this gene is spxA

Identifier: 116515656

GI number: 116515656

Start: 1266957

End: 1267358

Strand: Reverse

Name: spxA

Synonym: SPD_1236

Alternate gene names: 116515656

Gene position: 1267358-1266957 (Counterclockwise)

Preceding gene: 116515535

Following gene: 116516476

Centisome position: 61.94

GC content: 36.32

Gene sequence:

>402_bases
ATGATTACACTATTTCTATCACCGAGCTGTACATCATGTCGTAAGGCTAAGGCCTGGTTAGAAAAACATAAGGTTCCCTT
TGTGGAACACAATATTATGACCAGTCCTTTAACAAGAAAAGAATTGCAACACATCCTTTCCTTGACCGAAAATGGTACTG
ATGACATCATTTCAACTCGTTCAAAAATTTTTCAAAAATTGAATATTGATGTAGAGAGTATTTCGGTATCGGAATTGCTT
CATTTGATTGAGCAGTATCCTAGTCTTTTGCGTCGTCCAATTATTATTGATGCCAAGCGTATGCAAATCGGTTTTAATGA
AGATGAGATTCGTGCTTTTCTCCCTCGTAGTTATCGTAAGCAAGAACTAAAAGAAGCAAGAATGAGAGCTGGTATTAGTT
AA

Upstream 100 bases:

>100_bases
TTTTCTTGAAAAAATAGGCTTTTTTTCTAAAAATCCCTAGTCAAGCGCCTTATTTTTTTGTATAATAGAAGTAGCAAAGT
ATAGATAAGAAGAGAAAAGC

Downstream 100 bases:

>100_bases
TGAACAAACAGTATAGTTACCCACTAGATTTGTCGTGGAGCACTGAAGAACTTGCTTCAGTGCTTTCTTTTTTTAATGAT
GTTGAAGCTGCCTATGAAGG

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTRSKIFQKLNIDVESISVSELL
HLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRKQELKEARMRAGIS

Sequences:

>Translated_133_residues
MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTRSKIFQKLNIDVESISVSELL
HLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRKQELKEARMRAGIS
>Mature_133_residues
MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTRSKIFQKLNIDVESISVSELL
HLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRKQELKEARMRAGIS

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX_STRPN (Q97Q26)

Other databases:

- EMBL:   AE005672
- PIR:   F95163
- RefSeq:   NP_345863.1
- ProteinModelPortal:   Q97Q26
- SMR:   Q97Q26
- EnsemblBacteria:   EBSTRT00000025281
- GeneID:   931424
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_1405
- TIGR:   SP_1405
- GeneTree:   EBGT00050000027616
- HOGENOM:   HBG734370
- OMA:   FTERNIF
- ProtClustDB:   PRK01655
- BioCyc:   SPNE170187-1:SP_1405-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 15450; Mature: 15450

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTR
CEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
SKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCHHHHHHHCCHHHHH
QELKEARMRAGIS
HHHHHHHHHCCCC
>Mature Secondary Structure
MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQHILSLTENGTDDIISTR
CEEEEECCCCHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
SKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQIGFNEDEIRAFLPRSYRK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCCHHHHHHHCCHHHHH
QELKEARMRAGIS
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916