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The map label for this gene is kup

Identifier: 116495785

GI number: 116495785

Start: 2330896

End: 2332950

Strand: Direct

Name: kup

Synonym: LSEI_2333

Alternate gene names: 116495785

Gene position: 2330896-2332950 (Clockwise)

Preceding gene: 116495784

Following gene: 116495789

Centisome position: 80.51

GC content: 47.35

Gene sequence:

>2055_bases
ATGGCGTCAGGCTTGACTGCTAATAAGAAACTGCGACATAAAATTACTGCCGCGGCTTTACTGGTAACCCTCGGTGTCGT
CTATGGCGATATCGGGACGTCACCACTATACGTAATGAAATCAATCGTTGCTGGCAACGGCGGCATGGGACATTTTGATA
CTGACTTTTTGGTCGGCTCAGTGTCCTTGATTTTCTGGACCCTGCTCATTATCACCACGGTTAAATATGTCTTGATTGCA
TTACGGGCTGATAACAATGGTGAAGGCGGGATCTTTGCGCTGTATACGCTTGTTCGCCAGCGCGCTCGTTGGTTGGTACT
GCCCGCCATGGTTGGCGGTGCTGCTCTGCTGGCAGATGGGATGCTGACACCGGCTGTGACCGTCACAACCGCGATTGAAG
GTTTGAAGGGTGTCCATATTAACGGCAACATCTTAATCGACAATCAGCAACAGGTGATTTGGGTCACCGTTTTGATCATT
ACCTTCCTGTTCTTCATTCAGCGATTTGGTACCGATCTGATTGGTAAGGCGTTTGGTCCGATCATGTTTGTCTGGTTTAC
ATTCTTAGGCGTTGCTGGCTTTATTGCCTTGTCAAAGGACTGGTCCATGTTGCGCGCCTTGAACCCTTATTACGCACTCC
ATTTATTGGTCAGTCCAGACAATAAAATGGGGCTCTTCATTCTTGGCAGTATTTTCCTAGCAACCACCGGTGCTGAGGCA
TTGTATTCTGACATGGGCCATGTTGGTCGCGGTAACATCTATCTCAGCTGGCCATATGTCAATATCTGTTTGGTGCTCAA
CTATTTTGGCCAAGCTGTCTGGCTGGATCAAAATTCCAAAGTAACGGCGTTCAACAAGATTACCGACTTCAATCCGTTCT
TTCAGATGTTGCCAGAAAGCATCCGGTTAGGCGCAATTATTTTAGCAACCTTGGCGGCGATCATCGCATCACAAGCATTG
ATTTCCGGCTCTTATACTCTGGTTTCCGAAGCTATTAAACTGCGCTTCTTGCCACGACTGCACATCATTTACCCAACAAG
GTTAAAGGGGCAGCTGTATATTCCAGTCGTCAACACCATTTTATGGTTGGCTTGCTTAGCGATCATTGGCTACTTCAAAA
CCAGTGCTGAAATGGAAGGCGCTTATGGCTTGGCCATCACCATTACTATGCTGATGACCACCCTACTGTTGTACCAATAC
CTGCGTTCGCGTCATGCGCCTGCTGTGGTTGCGATCGGGACATTGATCTTCTTTAGTGCCATTGAAACAGTCTTCTTCAT
CTCCAGCGCGGTTAAGTTCTTGCACGGTGGTTATGTCACCGCCATGATCGCGTTTATCATTTTGGCCGTGATGTATGTCT
GGCAATACGGTGGCAGAATTCGCGACGACAACACTTATCGGGCCGAAATGGCTTCGCTTTTTGCCTATAAAAATCAACTG
TCCGAACTTCGCAACGATCCAGATTATCCAACATACACCACCAACTTGGTTTACATGACCCAAATTGCGAATGACCATTA
CATCAAAAAGGAAATTCTCTACTCAATTTTGGACAAACGGCCAAAACGCGCACGGGTTTACTGGTTTGTTACTGTCAATG
TTACGGATGAACCGTATACCGCCGAATATACAACGGATACGTATGGGACCGATTATATGGTCAACGTCCAACTCTATCTC
GGCTTCCGGATGGAACAACAGGTCAACGTGTTCTTACGGCAAATTGTCAATGACATGATGCGTGAAGGTGAATTACCAAC
GCAACCGCAAAAATACACAACCATTCCTGATCGACAAGTTGGCGACTGGACTTTTGTCTTGCTGCACGAAGAACTTTCAC
CGCAGACCCAGATCAAAGGTTTCCAGAAGGCCATCATTCAGGCGCGGCTACGACTCCAGCACATCGCAGTTTCACCCGCG
CAATGGTTCGGCTTGGAATATGCGGATACCATCGATGAAACCGTGCCACTGGTTCTTGGTAAAATTCCGATTACCAAACT
CAATCGACTAACGCGTTCCCAAGCAGAAGCTCAACCCGAAGATGAAGACGATTAA

Upstream 100 bases:

>100_bases
AACTAAATTTATTATTCAGGCGAACGAATGCCGCAAGTTCGCCTTACAATATGTCGTGATTCTGCTACAATGACGGTATT
ACTTTTCAGGAGGCTCAAAA

Downstream 100 bases:

>100_bases
GTCGCGTTACTAAAAAGAAGCTATATCTGATGCACAGCATTCTGCTGGGCGCGATATAGCTTCTTTTTTATCCATCAAGT
CGATTTTCGTTTTTTGTAAA

Product: K+ transporter

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGSVSLIFWTLLIITTVKYVLIA
LRADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADGMLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTVLII
TFLFFIQRFGTDLIGKAFGPIMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEA
LYSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPESIRLGAIILATLAAIIASQAL
ISGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTILWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQY
LRSRHAPAVVAIGTLIFFSAIETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQL
SELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYTAEYTTDTYGTDYMVNVQLYL
GFRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQVGDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPA
QWFGLEYADTIDETVPLVLGKIPITKLNRLTRSQAEAQPEDEDD

Sequences:

>Translated_684_residues
MASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGSVSLIFWTLLIITTVKYVLIA
LRADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADGMLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTVLII
TFLFFIQRFGTDLIGKAFGPIMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEA
LYSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPESIRLGAIILATLAAIIASQAL
ISGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTILWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQY
LRSRHAPAVVAIGTLIFFSAIETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQL
SELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYTAEYTTDTYGTDYMVNVQLYL
GFRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQVGDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPA
QWFGLEYADTIDETVPLVLGKIPITKLNRLTRSQAEAQPEDEDD
>Mature_683_residues
ASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGSVSLIFWTLLIITTVKYVLIAL
RADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADGMLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTVLIIT
FLFFIQRFGTDLIGKAFGPIMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEAL
YSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPESIRLGAIILATLAAIIASQALI
SGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTILWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQYL
RSRHAPAVVAIGTLIFFSAIETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQLS
ELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYTAEYTTDTYGTDYMVNVQLYLG
FRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQVGDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPAQ
WFGLEYADTIDETVPLVLGKIPITKLNRLTRSQAEAQPEDEDD

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=546, Percent_Identity=35.1648351648352, Blast_Score=276, Evalue=4e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP_LACC3 (Q035P5)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_807519.1
- STRING:   Q035P5
- GeneID:   4420897
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_2333
- eggNOG:   COG3158
- HOGENOM:   HBG351154
- OMA:   HLLFSPE
- PhylomeDB:   Q035P5
- ProtClustDB:   CLSK770921
- BioCyc:   LCAS321967:LSEI_2333-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 76692; Mature: 76560

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15544be4)-; HASH(0x175ba5b8)-; HASH(0x171121f8)-; HASH(0x175ba4d4)-; HASH(0x175b6da8)-; HASH(0x13a633f0)-; HASH(0x154ed8f4)-; HASH(0x154ed7c8)-; HASH(0x175b3cdc)-; HASH(0x13a63738)-; HASH(0x175b6b50)-; HASH(0x12f11704)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VSLIFWTLLIITTVKYVLIALRADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADG
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCEEEEHHHHCCHHHHHCC
MLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTVLIITFLFFIQRFGTDLIGKAFGP
CCCCHHHHHHHHHCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEA
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHH
LYSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPES
HHHHCCCCCCCCEEEECCHHHHHHHHHHHCCEEEECCCCCEEEECCCCCCCHHHHHCHHH
IRLGAIILATLAAIIASQALISGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHH
LWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQYLRSRHAPAVVAIGTLIFFSA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHH
SELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYT
HHHCCCCCCCCEEECEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCE
AEYTTDTYGTDYMVNVQLYLGFRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQV
EEEECCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPAQWFGLEYADTIDETVPLVLG
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHC
KIPITKLNRLTRSQAEAQPEDEDD
CCCHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure 
ASGLTANKKLRHKITAAALLVTLGVVYGDIGTSPLYVMKSIVAGNGGMGHFDTDFLVGS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VSLIFWTLLIITTVKYVLIALRADNNGEGGIFALYTLVRQRARWLVLPAMVGGAALLADG
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCEEEEHHHHCCHHHHHCC
MLTPAVTVTTAIEGLKGVHINGNILIDNQQQVIWVTVLIITFLFFIQRFGTDLIGKAFGP
CCCCHHHHHHHHHCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
IMFVWFTFLGVAGFIALSKDWSMLRALNPYYALHLLVSPDNKMGLFILGSIFLATTGAEA
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCHHH
LYSDMGHVGRGNIYLSWPYVNICLVLNYFGQAVWLDQNSKVTAFNKITDFNPFFQMLPES
HHHHCCCCCCCCEEEECCHHHHHHHHHHHCCEEEECCCCCEEEECCCCCCCHHHHHCHHH
IRLGAIILATLAAIIASQALISGSYTLVSEAIKLRFLPRLHIIYPTRLKGQLYIPVVNTI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHH
LWLACLAIIGYFKTSAEMEGAYGLAITITMLMTTLLLYQYLRSRHAPAVVAIGTLIFFSA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IETVFFISSAVKFLHGGYVTAMIAFIILAVMYVWQYGGRIRDDNTYRAEMASLFAYKNQL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHH
SELRNDPDYPTYTTNLVYMTQIANDHYIKKEILYSILDKRPKRARVYWFVTVNVTDEPYT
HHHCCCCCCCCEEECEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCE
AEYTTDTYGTDYMVNVQLYLGFRMEQQVNVFLRQIVNDMMREGELPTQPQKYTTIPDRQV
EEEECCCCCCCEEEEEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
GDWTFVLLHEELSPQTQIKGFQKAIIQARLRLQHIAVSPAQWFGLEYADTIDETVPLVLG
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHC
KIPITKLNRLTRSQAEAQPEDEDD
CCCHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA