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The map label for this gene is fimB [C]

Identifier: 116495444

GI number: 116495444

Start: 1949483

End: 1950646

Strand: Direct

Name: fimB [C]

Synonym: LSEI_1978

Alternate gene names: 116495444

Gene position: 1949483-1950646 (Clockwise)

Preceding gene: 116495443

Following gene: 116495447

Centisome position: 67.33

GC content: 42.7

Gene sequence:

>1164_bases
ATGCCAAAATGGACACCATACAAACGCCATCCCGGGGTGTATGAATACCAAACCAAGAAGGGAAAAAGGTTTGGAGTCAG
ACGAACCTATGATGATGCTATGGGAGAAAGAAAAGAGTTCTCAAAATCCGGTTTCATCCATTGGCAAGATGCTGATATTG
AGATCAAACGGTTTGAGGCAAAACTTGTCAGCGGTGAAGTATCGGGATCTTTGGCTAACAGAATGACCATTGATCAATAT
TACCAGCAAATGGCAAAACGAAAAATGAAAATGGGTATCTGGCGTGAATCAACAGCAAGAGCGAACGGAAACTTCTATTC
AAAGTATCTTAAGCCGGCATTTGGCAAAACACCTCTACAAGATGTATCAAGAGCCAAATATCAGCGTTTTCTCGATGAGT
TATCACAATCAGGTCTAGCGTTAACAACTGTCCATACTATTGATGCTGTCATGAAGAGCATCATGAATGCTGCTGAATTT
GAGGATGTCATCGACAAAAATCGGCTTCGAGGTATGCAGATCAATGGGAAAGCCCCTCGAAATAAGGATTTAGAACCACA
TTCATTTGAGCTGTGGCTAAATGCAGCAAAGACGAATCTGGATAAGTACGAAATGGCCTTGATCATCACTGCAACGCTCG
GGCTTCGCCGCGGAGAAGTGATGGGACTTCGAAACGAGTCCATCAAAATATCCCACGATCAAATCAACGATGCCGATGTC
GCGCAAATATCGATTGACATGCAACGCAACACAAATGAACTTAATGGCGGCCCACTCAAGACCAAATCATCGTACAGAAC
CATATGGGCATTTGGCAAAACCGTTGATCATTTGAAGTACGCAATGATTACGGCTGATAATCTAAGGCAAAGGAACAATA
TTCAAGCTGAGAAACATTGGCTGTGGCTTAACAATGATGGTAACCCGTTGCACCCCACCCATCTCAATCGATTGATGCGG
AGAGTAAGCAATAGGTCCGGCGTTGAAGTGTACCCACATTTGCTCAGGCATTATTTTGCAACACAAGCGATTGCTGCCAA
CAAACCACAAATTGATGTCATGCACTATCTCGGACATAAGAATCTTCAAATGACAGCAGACTACACCCGTTCAACAAAAG
CCGCTAGTCTAAATGTTTTTAATAGTATTGATAAGTTTCTTTAA

Upstream 100 bases:

>100_bases
TAGTCCCAATTATGGGGCTTTTATTTTAATGGCAAAACGAACATACGTTTGAATTTATGTACAAATCAATCAACTTAATA
GACAAATTGGAGGTATTATC

Downstream 100 bases:

>100_bases
TTTCTATATGGGATTTTTTGATTTTGAAAATATCCCACATAATCTCCCACAAATAAGGAACACTTACACGATATTAAAAA
GCAAAAACGACAAACAAAAA

Product: integrase

Products: NA

Alternate protein names: Integrase Family Protein; Phage Integrase; Site-Specific Recombinase; Phage Integrase Family Site Specific Recombinase; DNA Integration/Recombination/Inversion Protein; Phage Integrase Family Protein; Prophage Lp1 Integrase; TraSAIntegrase Fusion Protein; Tyrosine Recombinase XerC; DNA Integration/Recombination/Invertion Protein; Tyrosine Recombinase XerC-Like Protein

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPKWTPYKRHPGVYEYQTKKGKRFGVRRTYDDAMGERKEFSKSGFIHWQDADIEIKRFEAKLVSGEVSGSLANRMTIDQY
YQQMAKRKMKMGIWRESTARANGNFYSKYLKPAFGKTPLQDVSRAKYQRFLDELSQSGLALTTVHTIDAVMKSIMNAAEF
EDVIDKNRLRGMQINGKAPRNKDLEPHSFELWLNAAKTNLDKYEMALIITATLGLRRGEVMGLRNESIKISHDQINDADV
AQISIDMQRNTNELNGGPLKTKSSYRTIWAFGKTVDHLKYAMITADNLRQRNNIQAEKHWLWLNNDGNPLHPTHLNRLMR
RVSNRSGVEVYPHLLRHYFATQAIAANKPQIDVMHYLGHKNLQMTADYTRSTKAASLNVFNSIDKFL

Sequences:

>Translated_387_residues
MPKWTPYKRHPGVYEYQTKKGKRFGVRRTYDDAMGERKEFSKSGFIHWQDADIEIKRFEAKLVSGEVSGSLANRMTIDQY
YQQMAKRKMKMGIWRESTARANGNFYSKYLKPAFGKTPLQDVSRAKYQRFLDELSQSGLALTTVHTIDAVMKSIMNAAEF
EDVIDKNRLRGMQINGKAPRNKDLEPHSFELWLNAAKTNLDKYEMALIITATLGLRRGEVMGLRNESIKISHDQINDADV
AQISIDMQRNTNELNGGPLKTKSSYRTIWAFGKTVDHLKYAMITADNLRQRNNIQAEKHWLWLNNDGNPLHPTHLNRLMR
RVSNRSGVEVYPHLLRHYFATQAIAANKPQIDVMHYLGHKNLQMTADYTRSTKAASLNVFNSIDKFL
>Mature_386_residues
PKWTPYKRHPGVYEYQTKKGKRFGVRRTYDDAMGERKEFSKSGFIHWQDADIEIKRFEAKLVSGEVSGSLANRMTIDQYY
QQMAKRKMKMGIWRESTARANGNFYSKYLKPAFGKTPLQDVSRAKYQRFLDELSQSGLALTTVHTIDAVMKSIMNAAEFE
DVIDKNRLRGMQINGKAPRNKDLEPHSFELWLNAAKTNLDKYEMALIITATLGLRRGEVMGLRNESIKISHDQINDADVA
QISIDMQRNTNELNGGPLKTKSSYRTIWAFGKTVDHLKYAMITADNLRQRNNIQAEKHWLWLNNDGNPLHPTHLNRLMRR
VSNRSGVEVYPHLLRHYFATQAIAANKPQIDVMHYLGHKNLQMTADYTRSTKAASLNVFNSIDKFL

Specific function: Fimb Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fimb Switches

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44665; Mature: 44533

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKWTPYKRHPGVYEYQTKKGKRFGVRRTYDDAMGERKEFSKSGFIHWQDADIEIKRFEA
CCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCHHHHHHCCCCEEEECCCEEEEEHHH
KLVSGEVSGSLANRMTIDQYYQQMAKRKMKMGIWRESTARANGNFYSKYLKPAFGKTPLQ
HHHCCHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHH
DVSRAKYQRFLDELSQSGLALTTVHTIDAVMKSIMNAAEFEDVIDKNRLRGMQINGKAPR
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
NKDLEPHSFELWLNAAKTNLDKYEMALIITATLGLRRGEVMGLRNESIKISHDQINDADV
CCCCCCCEEEEEEEHHHCCCCHHHEEEEEEEHHCCCCCCEEECCCCCEEEECCCCCCCCE
AQISIDMQRNTNELNGGPLKTKSSYRTIWAFGKTVDHLKYAMITADNLRQRNNIQAEKHW
EEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHEEEHHHHHHHCCCCCEEEE
LWLNNDGNPLHPTHLNRLMRRVSNRSGVEVYPHLLRHYFATQAIAANKPQIDVMHYLGHK
EEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC
NLQMTADYTRSTKAASLNVFNSIDKFL
CEEEEECCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKWTPYKRHPGVYEYQTKKGKRFGVRRTYDDAMGERKEFSKSGFIHWQDADIEIKRFEA
CCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHCHHHHHHCCCCEEEECCCEEEEEHHH
KLVSGEVSGSLANRMTIDQYYQQMAKRKMKMGIWRESTARANGNFYSKYLKPAFGKTPLQ
HHHCCHHCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCHH
DVSRAKYQRFLDELSQSGLALTTVHTIDAVMKSIMNAAEFEDVIDKNRLRGMQINGKAPR
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
NKDLEPHSFELWLNAAKTNLDKYEMALIITATLGLRRGEVMGLRNESIKISHDQINDADV
CCCCCCCEEEEEEEHHHCCCCHHHEEEEEEEHHCCCCCCEEECCCCCEEEECCCCCCCCE
AQISIDMQRNTNELNGGPLKTKSSYRTIWAFGKTVDHLKYAMITADNLRQRNNIQAEKHW
EEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHEEEHHHHHHHCCCCCEEEE
LWLNNDGNPLHPTHLNRLMRRVSNRSGVEVYPHLLRHYFATQAIAANKPQIDVMHYLGHK
EEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC
NLQMTADYTRSTKAASLNVFNSIDKFL
CEEEEECCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA