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The map label for this gene is speF [H]

Identifier: 116495135

GI number: 116495135

Start: 1649173

End: 1651263

Strand: Direct

Name: speF [H]

Synonym: LSEI_1654

Alternate gene names: 116495135

Gene position: 1649173-1651263 (Clockwise)

Preceding gene: 116495132

Following gene: 116495138

Centisome position: 56.96

GC content: 49.98

Gene sequence:

>2091_bases
ATGCACTTATATATCGGCTACTCAGAAAAAGTAGCAGCAAGGATACTGCCCACCAATTGGCGTTGTTTAACTGCGGCACC
GTTAGCTGCCTTTGGCGCAGCAATCATCGATGCCTCTGACACTGCAACGCTCACTCAGCTTGTGGCCAGCCAATTACCCT
TACCAACTTTTATCATCGGCCAGATACCAATCAGTCACACTGGTCAGCTGACAATCACCAACATCGATACACTTAATACC
GCAACGATGGCTCAGATTACTGCTGCTGCACAAGCTTATGAGCAAACCATGGTACCAGCATTCATTCGCGACTTACTGGA
CTATGCGAAGGCGGACCCAACCAGCTTTGCGACTCCTGGCCACCACAGCGGTCACTACGACGACTTAGCACCAGCAGGCT
ACTTACTTCATCAGGCTTACGGCCCAACTTTCTTCGCTAGCGATACCAGCGATGTCGTCACTTCTTTGGGCGATATGTTA
ACACATGGGGGCACCCCGCTAGCTGCCGAAGAAGCGACAGCGCAGTTATATCATGCCGATGAAACTTATTTTGTGACCAA
CGGCACGACTGGATCGAATAACACTGTGGCCAGTGCATTGCTCACGCCAGGCGATTTGGTTTTATTCGATCGGAATAACC
ACAAATCTTTTTATAACGCGGCACTCATTCAAAATGATGCCCGCCCGGTTTATTTGGATACACTTCGAACGAAACGTGGT
TTGATTGGTCCGATCGATTTACAGAATCTAACCCATGAAAGTTTGCGACAAATGGCGGTAGCGGTGGCTCCCGAAAAGGC
ACATCAATCGCGGCCATTTCGACTGACAATTCTTGAACTAGAAACCTTTGATGGCATTGTGCCAAATGTCCGTCAGTTAA
TCGATCTTTTTGGGCCTTTAACCGACTACATTGCTTTCGATGCTGCTTGGGGTGGTTATGAGCCGTTTATTCCAGCAATG
ACGCCCATGGATCCCCTGCAGGTACCGCTTGCGCCGACTGACCCTGGTATCATCGTCACCCAAAGTGTCCACAAACAGCA
ATCCGGGTTTGGCCAGGCATCACAGATTCATAAAAAAGATGCCCATATTAAGGGACAAGCGCGATATGTCGGTCACGAAC
AGCTCAACCACGCGTACTTAAAACATGTTACGACCAGCTACAATTATCCGCTTTACGCGTCATTAGTCGCCAACACTGCC
ATTAATCAAGGTGCTCGCGGACAAAAAATCTGGCAAGATGCCATTCGAGCAGCACTCGGCTTTCGCCGCTCGCTCAACGA
TTCGCGACTCTTTTCTGCTTACGAACCGCCTGAGTTGACAACTTTGCCTGCTGATCAGGCCATTCAGACTGCTGAGGCTT
GGTCCATGACGCCACAAGCTGCATGGCATCAACTCGCAGGCCTTCAACCTGATCAAGCATTTCTTGATCCAGGTAAAGTG
ACCGTGCTATTACCTGACACAGCCGCATTTGGCATCAGCGGTTGGTTAGTAGATCGTTATTTACTTGACCACGGCATTAT
TCCGGAAAAAGCCGACCTAAATAGCCTGCTTTTTTTAGTGACGCCGGGAACCACTCGACCAGACTGGCAACGATTGCGCC
AAGTGTTAGCGCAGTTTGAAGCCGATTATTTTGCAAATAAAACCGTTGCTGAAAGTTTGCCAAAATTAGTCGCTGAAACT
GACGAGGCGTATGCACATCAAACATTACGCGAGCTAGGTCAGACCATGTCGGACTTTTTCCGAGAAGCGCACCTAGCTGA
GCAACAACGTGACTTGTTTACCAACACCAACGCCATCCCCACTGCCATGACCCCGCAAGCCGCCGATCGTTATTTTGTTC
GCGGTCAAATTGACACCATCCCTCTGGATCAAGCCACGGGCCGCATCGCAGTCGACGGCGCGCTGCCCTATCCGCCCGGA
ATCTTTGTGGTTGTCCCTGGCGAACGCTGGCGACCGGAAGCGATCAGTTACTTTCAAACACTTTTTGAAGGTATACGGCA
CTTCCCCGGCTTTACCCCAGAAATCCAAGGCGTTATCGCTCGTGCAGGTGGTCAGCCATATGTTCATGTTGTTCATGAAC
AACTTTCATAG

Upstream 100 bases:

>100_bases
AGAAGGCATCGAAGACACAGTCTTTGAAGTCACTCTAAAAATTTTCCGTTTAACATTATGTTAAAATCAACTGAATCTAT
TTTGAAAGGAACTCGCAGGC

Downstream 100 bases:

>100_bases
CCGTCAAAAAACGCGATCAATTAGCTTGATCGCGTTTTTTTGCTTAGCCGATTCTAGTTATCAAAGAAAGTGGACTGCGC
GGCTCCCATGGTCGCCAATT

Product: arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MHLYIGYSEKVAARILPTNWRCLTAAPLAAFGAAIIDASDTATLTQLVASQLPLPTFIIGQIPISHTGQLTITNIDTLNT
ATMAQITAAAQAYEQTMVPAFIRDLLDYAKADPTSFATPGHHSGHYDDLAPAGYLLHQAYGPTFFASDTSDVVTSLGDML
THGGTPLAAEEATAQLYHADETYFVTNGTTGSNNTVASALLTPGDLVLFDRNNHKSFYNAALIQNDARPVYLDTLRTKRG
LIGPIDLQNLTHESLRQMAVAVAPEKAHQSRPFRLTILELETFDGIVPNVRQLIDLFGPLTDYIAFDAAWGGYEPFIPAM
TPMDPLQVPLAPTDPGIIVTQSVHKQQSGFGQASQIHKKDAHIKGQARYVGHEQLNHAYLKHVTTSYNYPLYASLVANTA
INQGARGQKIWQDAIRAALGFRRSLNDSRLFSAYEPPELTTLPADQAIQTAEAWSMTPQAAWHQLAGLQPDQAFLDPGKV
TVLLPDTAAFGISGWLVDRYLLDHGIIPEKADLNSLLFLVTPGTTRPDWQRLRQVLAQFEADYFANKTVAESLPKLVAET
DEAYAHQTLRELGQTMSDFFREAHLAEQQRDLFTNTNAIPTAMTPQAADRYFVRGQIDTIPLDQATGRIAVDGALPYPPG
IFVVVPGERWRPEAISYFQTLFEGIRHFPGFTPEIQGVIARAGGQPYVHVVHEQLS

Sequences:

>Translated_696_residues
MHLYIGYSEKVAARILPTNWRCLTAAPLAAFGAAIIDASDTATLTQLVASQLPLPTFIIGQIPISHTGQLTITNIDTLNT
ATMAQITAAAQAYEQTMVPAFIRDLLDYAKADPTSFATPGHHSGHYDDLAPAGYLLHQAYGPTFFASDTSDVVTSLGDML
THGGTPLAAEEATAQLYHADETYFVTNGTTGSNNTVASALLTPGDLVLFDRNNHKSFYNAALIQNDARPVYLDTLRTKRG
LIGPIDLQNLTHESLRQMAVAVAPEKAHQSRPFRLTILELETFDGIVPNVRQLIDLFGPLTDYIAFDAAWGGYEPFIPAM
TPMDPLQVPLAPTDPGIIVTQSVHKQQSGFGQASQIHKKDAHIKGQARYVGHEQLNHAYLKHVTTSYNYPLYASLVANTA
INQGARGQKIWQDAIRAALGFRRSLNDSRLFSAYEPPELTTLPADQAIQTAEAWSMTPQAAWHQLAGLQPDQAFLDPGKV
TVLLPDTAAFGISGWLVDRYLLDHGIIPEKADLNSLLFLVTPGTTRPDWQRLRQVLAQFEADYFANKTVAESLPKLVAET
DEAYAHQTLRELGQTMSDFFREAHLAEQQRDLFTNTNAIPTAMTPQAADRYFVRGQIDTIPLDQATGRIAVDGALPYPPG
IFVVVPGERWRPEAISYFQTLFEGIRHFPGFTPEIQGVIARAGGQPYVHVVHEQLS
>Mature_696_residues
MHLYIGYSEKVAARILPTNWRCLTAAPLAAFGAAIIDASDTATLTQLVASQLPLPTFIIGQIPISHTGQLTITNIDTLNT
ATMAQITAAAQAYEQTMVPAFIRDLLDYAKADPTSFATPGHHSGHYDDLAPAGYLLHQAYGPTFFASDTSDVVTSLGDML
THGGTPLAAEEATAQLYHADETYFVTNGTTGSNNTVASALLTPGDLVLFDRNNHKSFYNAALIQNDARPVYLDTLRTKRG
LIGPIDLQNLTHESLRQMAVAVAPEKAHQSRPFRLTILELETFDGIVPNVRQLIDLFGPLTDYIAFDAAWGGYEPFIPAM
TPMDPLQVPLAPTDPGIIVTQSVHKQQSGFGQASQIHKKDAHIKGQARYVGHEQLNHAYLKHVTTSYNYPLYASLVANTA
INQGARGQKIWQDAIRAALGFRRSLNDSRLFSAYEPPELTTLPADQAIQTAEAWSMTPQAAWHQLAGLQPDQAFLDPGKV
TVLLPDTAAFGISGWLVDRYLLDHGIIPEKADLNSLLFLVTPGTTRPDWQRLRQVLAQFEADYFANKTVAESLPKLVAET
DEAYAHQTLRELGQTMSDFFREAHLAEQQRDLFTNTNAIPTAMTPQAADRYFVRGQIDTIPLDQATGRIAVDGALPYPPG
IFVVVPGERWRPEAISYFQTLFEGIRHFPGFTPEIQGVIARAGGQPYVHVVHEQLS

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=668, Percent_Identity=39.9700598802395, Blast_Score=520, Evalue=1e-148,
Organism=Escherichia coli, GI87082193, Length=663, Percent_Identity=40.8748114630468, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI221142684, Length=635, Percent_Identity=30.5511811023622, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1790573, Length=632, Percent_Identity=30.5379746835443, Blast_Score=275, Evalue=9e-75,
Organism=Escherichia coli, GI1786384, Length=621, Percent_Identity=30.9178743961353, Blast_Score=270, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 76331; Mature: 76331

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLYIGYSEKVAARILPTNWRCLTAAPLAAFGAAIIDASDTATLTQLVASQLPLPTFIIG
CEEEEECCHHHHHEECCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
QIPISHTGQLTITNIDTLNTATMAQITAAAQAYEQTMVPAFIRDLLDYAKADPTSFATPG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
HHSGHYDDLAPAGYLLHQAYGPTFFASDTSDVVTSLGDMLTHGGTPLAAEEATAQLYHAD
CCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECC
ETYFVTNGTTGSNNTVASALLTPGDLVLFDRNNHKSFYNAALIQNDARPVYLDTLRTKRG
CEEEEECCCCCCCCHHHHEEECCCCEEEEECCCCCCHHHHHHEECCCCEEEEEHHHHCCC
LIGPIDLQNLTHESLRQMAVAVAPEKAHQSRPFRLTILELETFDGIVPNVRQLIDLFGPL
CCCCCCHHHCCHHHHHHHHHHCCCHHHHCCCCEEEEEEEEEHHCCCCHHHHHHHHHHHHH
TDYIAFDAAWGGYEPFIPAMTPMDPLQVPLAPTDPGIIVTQSVHKQQSGFGQASQIHKKD
HHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHC
AHIKGQARYVGHEQLNHAYLKHVTTSYNYPLYASLVANTAINQGARGQKIWQDAIRAALG
CCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FRRSLNDSRLFSAYEPPELTTLPADQAIQTAEAWSMTPQAAWHQLAGLQPDQAFLDPGKV
HHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCE
TVLLPDTAAFGISGWLVDRYLLDHGIIPEKADLNSLLFLVTPGTTRPDWQRLRQVLAQFE
EEEECCCHHHCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ADYFANKTVAESLPKLVAETDEAYAHQTLRELGQTMSDFFREAHLAEQQRDLFTNTNAIP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TAMTPQAADRYFVRGQIDTIPLDQATGRIAVDGALPYPPGIFVVVPGERWRPEAISYFQT
CCCCCHHCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
LFEGIRHFPGFTPEIQGVIARAGGQPYVHVVHEQLS
HHHHHHHCCCCCHHHHHHHHHCCCCCEEEEHEHHCC
>Mature Secondary Structure
MHLYIGYSEKVAARILPTNWRCLTAAPLAAFGAAIIDASDTATLTQLVASQLPLPTFIIG
CEEEEECCHHHHHEECCCCCEEEECCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
QIPISHTGQLTITNIDTLNTATMAQITAAAQAYEQTMVPAFIRDLLDYAKADPTSFATPG
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
HHSGHYDDLAPAGYLLHQAYGPTFFASDTSDVVTSLGDMLTHGGTPLAAEEATAQLYHAD
CCCCCCCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEECC
ETYFVTNGTTGSNNTVASALLTPGDLVLFDRNNHKSFYNAALIQNDARPVYLDTLRTKRG
CEEEEECCCCCCCCHHHHEEECCCCEEEEECCCCCCHHHHHHEECCCCEEEEEHHHHCCC
LIGPIDLQNLTHESLRQMAVAVAPEKAHQSRPFRLTILELETFDGIVPNVRQLIDLFGPL
CCCCCCHHHCCHHHHHHHHHHCCCHHHHCCCCEEEEEEEEEHHCCCCHHHHHHHHHHHHH
TDYIAFDAAWGGYEPFIPAMTPMDPLQVPLAPTDPGIIVTQSVHKQQSGFGQASQIHKKD
HHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHCCCCCHHHHHHHC
AHIKGQARYVGHEQLNHAYLKHVTTSYNYPLYASLVANTAINQGARGQKIWQDAIRAALG
CCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FRRSLNDSRLFSAYEPPELTTLPADQAIQTAEAWSMTPQAAWHQLAGLQPDQAFLDPGKV
HHHCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCE
TVLLPDTAAFGISGWLVDRYLLDHGIIPEKADLNSLLFLVTPGTTRPDWQRLRQVLAQFE
EEEECCCHHHCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
ADYFANKTVAESLPKLVAETDEAYAHQTLRELGQTMSDFFREAHLAEQQRDLFTNTNAIP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TAMTPQAADRYFVRGQIDTIPLDQATGRIAVDGALPYPPGIFVVVPGERWRPEAISYFQT
CCCCCHHCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHH
LFEGIRHFPGFTPEIQGVIARAGGQPYVHVVHEQLS
HHHHHHHCCCCCHHHHHHHHHCCCCCEEEEHEHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]