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The map label for this gene is pepX

Identifier: 116495132

GI number: 116495132

Start: 1644556

End: 1646949

Strand: Direct

Name: pepX

Synonym: LSEI_1651

Alternate gene names: 116495132

Gene position: 1644556-1646949 (Clockwise)

Preceding gene: 116495113

Following gene: 116495135

Centisome position: 56.8

GC content: 48.12

Gene sequence:

>2394_bases
ATGAAATTAAATCAATTTGCCCGTTTGACACCTGACTTCAAGGTGCAAGTAGCGGAGCTTAAGCAGATTGGCCTGCAAGC
CGATCCTGATGACACTTTTAGTCAAAGTACGACCGACCTTTTCAATGCTTTTTTTCCAGAGGCTTATACTTTAGCCGCAA
AGAAAGATAAGCTCGCCCAAGTAGCAGTCAACATGGACCAAACACTAGCAGCATGGTTGGCGAAAAAACCATCCAAAATG
ACGCGCCGTGACTTTTATAATGTGGCGCTACAACTACTTGGCTTCGAAGCTTTCACTGACTTTGACCTGAATGATCCATT
TAAAATGATGACTGCAACCAAGTTACCAAGCCTCGATCACGATCTAACGAGCACCGCTGATTTGCTCAAGGCTGTTTATC
TATTGTTAAATACGCGAACCAAGCATTTGGTTAGTTATTTGGATGATCTAGCTAATCGCGGTTTTTTAAAAGACTTCCAG
AAAAAACAGAAAAAACCGACCCACCTTCTTTTTAACGGCAAAGTCCAACAAGTTTTTGATGCGCGGCAGGCGGTTCGTGA
AGTTGTTTGGATCGAATCGGATATGGATACCGATCACGATGGCCAACGCGACTTGCTCGAAGCGACTATTTACCGCCCGA
AAGCCACAGATCAAGGGCTTAAAGTGCCCGTGTTATTTACTGCAAATCCGTATTTTCATGGAACCAACGATGTGACTGCA
GTGACGCACGTGCCGGAAACGACCTTAGCTGTTAAAACACACGGAGCCTCGAAAGCTGAAGTTACGGCAAATCCTGAAGA
GCCTGCCAACTTGCCTCATCATCCAGTTAATGGCGAGGCGACACAGGCCGAAGCTTATGCCGAAGAAAACGGTATGTATG
CCTTTAACGATTATTTTCTCGCCCGTGGCTTTGCTGTGGTTTATTCGGCAGGTGTTGGCACTCGCTATTCCGACGGCTTC
CGGACAACCGGTGGCCCAGAAGAAACCGATGGTGCTGTTGCTGTCATCGAGTGGCTAACCGGTAAACGCCGCGCTTTTAC
GAACCGGACAGATGGTATTACCATCAAAGCTTGGTGGTCAACCGGTCTTGTCGCTATGACCGGCAAATCCTACCTGGCTA
CATTAGCCATGGCGGCGGCCACAACTGGGGTTGACGGTCTCAAGACAATTGTAGCCGACGCTGGCATTTCCAGCTGGTAT
GACTACTACCGTGAAAATGGTCTCGTAGTGGCCCCTGGTGGTTTCCAAGGTGAAGATGCGGATGTTCTGGCTGTGGATAC
CTTCTCCCGGCAAAAGTCCGGCGGCGACCTGATCAACATCAAACAAGCTTGGGAAAAGCATCTTGCTACGATCACTCACG
ATCAGGATCGAACAACTGGCGCTTACAACACATGGTGGGATGCGCGCAACTACCGGAAAAACGCTAACAAGGTCAAGGCA
GATGTGGTGTTGATCCATGGTCTTAATGATTGGAACGTAAAACCTACAAACGCCATCAAGTTTTGGGAGGCCATCGCAGA
CCTGCCAATTCAAAAGAAACTGGTTTTGCATCAAGGCCAGCACGTTTACGTCCACAATGTTCGCTCATTAGACTTTCTAG
ATATGATGAATTTGTGGCTCACACATGAATTGCTTGGTGAGGCGAATGGCGCCGAAGATGTTTTACCAAATGTTGTTGTG
CAAGATAATGTTGCTGTTCAGACTTGGTCGGCCTATCAGAATTTTGCCAGCCCAGCAGCAGAGCATGTGACCAACACTCG
CAATCTAAAAACGGATTTCGAGGCGGCCACGGATCAATTTACCGATCACGCAACAGCAACTTTTGATGCCCAGCATGATA
CCAGTGCCAGTTTCGAGACTGCCATCATCACCCCTAACAGTGCTTATGCCAATAGCCGCTTGTGGCTCACGCAGCCGCCA
CTTGAGCGCGACCAAACACTGGAAGGCATTCCGCACTTAGAGCTGACGCTGGCCATTGATGCCCCAACAGGTATTCTCAG
TGTTCGCCTCATTGATTTAGGAATGGCCAAGCGATTCGGTGAAACCGCGGCAACGGTGGCCTTAAACGGTCTTCAACTTG
GTTTTGATTATAAAACAACAGACATTCTCGAATTCAAACCAACGGCTAAACCGACACCAAGCAAGTTGATCTCGCTTGGC
CATATCAACCTGCAAAATCCAAAAAATGCTTACGAAGTGCAAAGGATTACGCCCGGCCAACCGTTCCATATCAGTTTGGA
TCTCCAACCCACCCACTATCATCTGCCAGCTGGTCGTCAACTCGCTTTGGTCATTCATGGGGCAGATATGGCCCAAACCA
TTCGCCCGATCAAAACAACTCATTATCAAATTGATTTGGCTAATAGCAGCATCACGCTCCCTTACCGCATTTAA

Upstream 100 bases:

>100_bases
GATCATCCGATACGCAAGTTAGACGGATATAGTTGAAAGCAGTCAATGAGACCGCTACACTGAATTTATCACAATTTTCT
CATAAAGGAAGACAATGCTG

Downstream 100 bases:

>100_bases
CTTAATAGGATGCTCACCAGCTTTTTCATGCATGATGCATCAAAAAAGGAGATATCAAGCGCCGCGTCGGCCTGACATCT
CCTTTTTTCTTACTTAACTG

Product: x-prolyl-dipeptidyl aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidyl-peptidase; X-prolyl-dipeptidyl aminopeptidase; X-PDAP

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MKLNQFARLTPDFKVQVAELKQIGLQADPDDTFSQSTTDLFNAFFPEAYTLAAKKDKLAQVAVNMDQTLAAWLAKKPSKM
TRRDFYNVALQLLGFEAFTDFDLNDPFKMMTATKLPSLDHDLTSTADLLKAVYLLLNTRTKHLVSYLDDLANRGFLKDFQ
KKQKKPTHLLFNGKVQQVFDARQAVREVVWIESDMDTDHDGQRDLLEATIYRPKATDQGLKVPVLFTANPYFHGTNDVTA
VTHVPETTLAVKTHGASKAEVTANPEEPANLPHHPVNGEATQAEAYAEENGMYAFNDYFLARGFAVVYSAGVGTRYSDGF
RTTGGPEETDGAVAVIEWLTGKRRAFTNRTDGITIKAWWSTGLVAMTGKSYLATLAMAAATTGVDGLKTIVADAGISSWY
DYYRENGLVVAPGGFQGEDADVLAVDTFSRQKSGGDLINIKQAWEKHLATITHDQDRTTGAYNTWWDARNYRKNANKVKA
DVVLIHGLNDWNVKPTNAIKFWEAIADLPIQKKLVLHQGQHVYVHNVRSLDFLDMMNLWLTHELLGEANGAEDVLPNVVV
QDNVAVQTWSAYQNFASPAAEHVTNTRNLKTDFEAATDQFTDHATATFDAQHDTSASFETAIITPNSAYANSRLWLTQPP
LERDQTLEGIPHLELTLAIDAPTGILSVRLIDLGMAKRFGETAATVALNGLQLGFDYKTTDILEFKPTAKPTPSKLISLG
HINLQNPKNAYEVQRITPGQPFHISLDLQPTHYHLPAGRQLALVIHGADMAQTIRPIKTTHYQIDLANSSITLPYRI

Sequences:

>Translated_797_residues
MKLNQFARLTPDFKVQVAELKQIGLQADPDDTFSQSTTDLFNAFFPEAYTLAAKKDKLAQVAVNMDQTLAAWLAKKPSKM
TRRDFYNVALQLLGFEAFTDFDLNDPFKMMTATKLPSLDHDLTSTADLLKAVYLLLNTRTKHLVSYLDDLANRGFLKDFQ
KKQKKPTHLLFNGKVQQVFDARQAVREVVWIESDMDTDHDGQRDLLEATIYRPKATDQGLKVPVLFTANPYFHGTNDVTA
VTHVPETTLAVKTHGASKAEVTANPEEPANLPHHPVNGEATQAEAYAEENGMYAFNDYFLARGFAVVYSAGVGTRYSDGF
RTTGGPEETDGAVAVIEWLTGKRRAFTNRTDGITIKAWWSTGLVAMTGKSYLATLAMAAATTGVDGLKTIVADAGISSWY
DYYRENGLVVAPGGFQGEDADVLAVDTFSRQKSGGDLINIKQAWEKHLATITHDQDRTTGAYNTWWDARNYRKNANKVKA
DVVLIHGLNDWNVKPTNAIKFWEAIADLPIQKKLVLHQGQHVYVHNVRSLDFLDMMNLWLTHELLGEANGAEDVLPNVVV
QDNVAVQTWSAYQNFASPAAEHVTNTRNLKTDFEAATDQFTDHATATFDAQHDTSASFETAIITPNSAYANSRLWLTQPP
LERDQTLEGIPHLELTLAIDAPTGILSVRLIDLGMAKRFGETAATVALNGLQLGFDYKTTDILEFKPTAKPTPSKLISLG
HINLQNPKNAYEVQRITPGQPFHISLDLQPTHYHLPAGRQLALVIHGADMAQTIRPIKTTHYQIDLANSSITLPYRI
>Mature_797_residues
MKLNQFARLTPDFKVQVAELKQIGLQADPDDTFSQSTTDLFNAFFPEAYTLAAKKDKLAQVAVNMDQTLAAWLAKKPSKM
TRRDFYNVALQLLGFEAFTDFDLNDPFKMMTATKLPSLDHDLTSTADLLKAVYLLLNTRTKHLVSYLDDLANRGFLKDFQ
KKQKKPTHLLFNGKVQQVFDARQAVREVVWIESDMDTDHDGQRDLLEATIYRPKATDQGLKVPVLFTANPYFHGTNDVTA
VTHVPETTLAVKTHGASKAEVTANPEEPANLPHHPVNGEATQAEAYAEENGMYAFNDYFLARGFAVVYSAGVGTRYSDGF
RTTGGPEETDGAVAVIEWLTGKRRAFTNRTDGITIKAWWSTGLVAMTGKSYLATLAMAAATTGVDGLKTIVADAGISSWY
DYYRENGLVVAPGGFQGEDADVLAVDTFSRQKSGGDLINIKQAWEKHLATITHDQDRTTGAYNTWWDARNYRKNANKVKA
DVVLIHGLNDWNVKPTNAIKFWEAIADLPIQKKLVLHQGQHVYVHNVRSLDFLDMMNLWLTHELLGEANGAEDVLPNVVV
QDNVAVQTWSAYQNFASPAAEHVTNTRNLKTDFEAATDQFTDHATATFDAQHDTSASFETAIITPNSAYANSRLWLTQPP
LERDQTLEGIPHLELTLAIDAPTGILSVRLIDLGMAKRFGETAATVALNGLQLGFDYKTTDILEFKPTAKPTPSKLISLG
HINLQNPKNAYEVQRITPGQPFHISLDLQPTHYHLPAGRQLALVIHGADMAQTIRPIKTTHYQIDLANSSITLPYRI

Specific function: Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S15 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PEPX_LACC3 (Q038E8)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806866.1
- ProteinModelPortal:   Q038E8
- SMR:   Q038E8
- STRING:   Q038E8
- MEROPS:   S15.001
- GeneID:   4419131
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1651
- eggNOG:   NOG04844
- HOGENOM:   HBG515455
- OMA:   NDWNVKP
- ProtClustDB:   PRK05371
- BioCyc:   LCAS321967:LSEI_1651-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_00698
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR008252
- InterPro:   IPR000383
- InterPro:   IPR015251
- PRINTS:   PR00923
- SMART:   SM00939
- SMART:   SM00940

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C; PF09168 PepX_N; SSF49785 Gal_bind_like; SSF81761 PepX_N

EC number: =3.4.14.11

Molecular weight: Translated: 88465; Mature: 88465

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 370-370 ACT_SITE 490-490 ACT_SITE 521-521

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNQFARLTPDFKVQVAELKQIGLQADPDDTFSQSTTDLFNAFFPEAYTLAAKKDKLAQ
CCCCCHHHCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
VAVNMDQTLAAWLAKKPSKMTRRDFYNVALQLLGFEAFTDFDLNDPFKMMTATKLPSLDH
HHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCC
DLTSTADLLKAVYLLLNTRTKHLVSYLDDLANRGFLKDFQKKQKKPTHLLFNGKVQQVFD
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHH
ARQAVREVVWIESDMDTDHDGQRDLLEATIYRPKATDQGLKVPVLFTANPYFHGTNDVTA
HHHHHHHHEEEECCCCCCCCCHHHHHHHHEECCCCCCCCCEEEEEEECCCCCCCCCCEEE
VTHVPETTLAVKTHGASKAEVTANPEEPANLPHHPVNGEATQAEAYAEENGMYAFNDYFL
EEECCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEHHHHH
ARGFAVVYSAGVGTRYSDGFRTTGGPEETDGAVAVIEWLTGKRRAFTNRTDGITIKAWWS
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCEEEEEECC
TGLVAMTGKSYLATLAMAAATTGVDGLKTIVADAGISSWYDYYRENGLVVAPGGFQGEDA
CCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCC
DVLAVDTFSRQKSGGDLINIKQAWEKHLATITHDQDRTTGAYNTWWDARNYRKNANKVKA
CEEEEECCCCCCCCCCEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCCEEEE
DVVLIHGLNDWNVKPTNAIKFWEAIADLPIQKKLVLHQGQHVYVHNVRSLDFLDMMNLWL
EEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
THELLGEANGAEDVLPNVVVQDNVAVQTWSAYQNFASPAAEHVTNTRNLKTDFEAATDQF
HHHHHHCCCCCHHHCCCEEEECCCEEEEHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHH
TDHATATFDAQHDTSASFETAIITPNSAYANSRLWLTQPPLERDQTLEGIPHLELTLAID
CCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHCCCCCEEEEEEEE
APTGILSVRLIDLGMAKRFGETAATVALNGLQLGFDYKTTDILEFKPTAKPTPSKLISLG
CCCCEEEEEEEHHHHHHHHCCHHHEEEEECEEECCCCCCCEEEEECCCCCCCHHHHEEEC
HINLQNPKNAYEVQRITPGQPFHISLDLQPTHYHLPAGRQLALVIHGADMAQTIRPIKTT
EEECCCCCCCEEEEECCCCCCEEEEEEECCCEEECCCCCEEEEEEECCHHHHHHHCCEEE
HYQIDLANSSITLPYRI
EEEEEECCCEEEEEEEC
>Mature Secondary Structure
MKLNQFARLTPDFKVQVAELKQIGLQADPDDTFSQSTTDLFNAFFPEAYTLAAKKDKLAQ
CCCCCHHHCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHH
VAVNMDQTLAAWLAKKPSKMTRRDFYNVALQLLGFEAFTDFDLNDPFKMMTATKLPSLDH
HHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCC
DLTSTADLLKAVYLLLNTRTKHLVSYLDDLANRGFLKDFQKKQKKPTHLLFNGKVQQVFD
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHH
ARQAVREVVWIESDMDTDHDGQRDLLEATIYRPKATDQGLKVPVLFTANPYFHGTNDVTA
HHHHHHHHEEEECCCCCCCCCHHHHHHHHEECCCCCCCCCEEEEEEECCCCCCCCCCEEE
VTHVPETTLAVKTHGASKAEVTANPEEPANLPHHPVNGEATQAEAYAEENGMYAFNDYFL
EEECCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEHHHHH
ARGFAVVYSAGVGTRYSDGFRTTGGPEETDGAVAVIEWLTGKRRAFTNRTDGITIKAWWS
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCEEEEEECC
TGLVAMTGKSYLATLAMAAATTGVDGLKTIVADAGISSWYDYYRENGLVVAPGGFQGEDA
CCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCC
DVLAVDTFSRQKSGGDLINIKQAWEKHLATITHDQDRTTGAYNTWWDARNYRKNANKVKA
CEEEEECCCCCCCCCCEEEHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHCCCCEEEE
DVVLIHGLNDWNVKPTNAIKFWEAIADLPIQKKLVLHQGQHVYVHNVRSLDFLDMMNLWL
EEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
THELLGEANGAEDVLPNVVVQDNVAVQTWSAYQNFASPAAEHVTNTRNLKTDFEAATDQF
HHHHHHCCCCCHHHCCCEEEECCCEEEEHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHH
TDHATATFDAQHDTSASFETAIITPNSAYANSRLWLTQPPLERDQTLEGIPHLELTLAID
CCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHCCCCCEEEEEEEE
APTGILSVRLIDLGMAKRFGETAATVALNGLQLGFDYKTTDILEFKPTAKPTPSKLISLG
CCCCEEEEEEEHHHHHHHHCCHHHEEEEECEEECCCCCCCEEEEECCCCCCCHHHHEEEC
HINLQNPKNAYEVQRITPGQPFHISLDLQPTHYHLPAGRQLALVIHGADMAQTIRPIKTT
EEECCCCCCCEEEEECCCCCCEEEEEEECCCEEECCCCCEEEEEEECCHHHHHHHCCEEE
HYQIDLANSSITLPYRI
EEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA