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The map label for this gene is hslV

Identifier: 116494890

GI number: 116494890

Start: 1392159

End: 1392683

Strand: Direct

Name: hslV

Synonym: LSEI_1404

Alternate gene names: 116494890

Gene position: 1392159-1392683 (Clockwise)

Preceding gene: 116494889

Following gene: 116494891

Centisome position: 48.08

GC content: 51.05

Gene sequence:

>525_bases
ATGACAACAATTGCAGCAGTAAGAAAAGATGGTGTGACCGCTTTGGCCGGTGACGGTCAGGTAACCCTTGGCGAAAAGGT
CATCATGAAAGGCAACGCGCAGAAAGTTCGCCGGATCTATCATGATCAAGTCGTCATCGGATTTGCCGGCGGGGTGGCAG
ATGCTTTCACCCTGCAAGACTGGTTTGAAAAGAAGCTGGAGCATTATGCTGGCAACTTGCGACGTTCCGCAGTTGCGCTG
GCTCAAGATTGGCGCAAGGATCCGACCTTGCAGAAACTTGAAGCCATGATGATCGTGATGGATGAGCATGACCTGTTACT
TGTATCCGGGTCTGGCGAAGTGATAGATCCAGATGAAGACGTGGTAGCGATCGGCTCCGGCGGCAACTTTGCGCAAGCCG
CGGCAATCGCGATGCTGCGGCATGCCCCAGATATGACACCAGCTGACATTGCCAAAGAAGCAGTGAATATCGCAGGGAAT
ATCGATATTTTCACAAACCACAATGTTATTGTCGAAAGCTTTTAG

Upstream 100 bases:

>100_bases
AAGCCTAAATAGCCAAAATTCAGCCATTTAGGCTTGCAGCCCACTTATGCTCCGGTTTCTAAGCGCTTCTGCTCGCGCTC
ACTTAAAAAGGAGCATGACT

Downstream 100 bases:

>100_bases
TTTGTAACCGTCGGCAATTACATTGACCTACAGGAGGCTTATGATGGCAGAAGTACAAACCCCAAAACAGATCGTTGAAA
AACTCGATCAATATGTCATT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVAL
AQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGN
IDIFTNHNVIVESF

Sequences:

>Translated_174_residues
MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVAL
AQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGN
IDIFTNHNVIVESF
>Mature_173_residues
TTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQDWFEKKLEHYAGNLRRSAVALA
QDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDEDVVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNI
DIFTNHNVIVESF

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=174, Percent_Identity=52.8735632183908, Blast_Score=186, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_LACC3 (Q039E0)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806624.1
- ProteinModelPortal:   Q039E0
- SMR:   Q039E0
- STRING:   Q039E0
- GeneID:   4419745
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1404
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q039E0
- ProtClustDB:   PRK05456
- BioCyc:   LCAS321967:LSEI_1404-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 18744; Mature: 18612

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: ACT_SITE 2-2

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQD
CCCHHHECCCCCEEEECCCEEEECCEEEECCCHHHHHHHHHCEEEEEECCCCCHHHHHHH
WFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDED
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCEEEEECCCCEECCCCC
VVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDIFTNHNVIVESF
EEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEC
>Mature Secondary Structure 
TTIAAVRKDGVTALAGDGQVTLGEKVIMKGNAQKVRRIYHDQVVIGFAGGVADAFTLQD
CCHHHECCCCCEEEECCCEEEECCEEEECCCHHHHHHHHHCEEEEEECCCCCHHHHHHH
WFEKKLEHYAGNLRRSAVALAQDWRKDPTLQKLEAMMIVMDEHDLLLVSGSGEVIDPDED
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCEEEEECCCCEECCCCC
VVAIGSGGNFAQAAAIAMLRHAPDMTPADIAKEAVNIAGNIDIFTNHNVIVESF
EEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA