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The map label for this gene is 116494819

Identifier: 116494819

GI number: 116494819

Start: 1313870

End: 1315552

Strand: Direct

Name: 116494819

Synonym: LSEI_1330

Alternate gene names: NA

Gene position: 1313870-1315552 (Clockwise)

Preceding gene: 116494818

Following gene: 116494820

Centisome position: 45.38

GC content: 45.4

Gene sequence:

>1683_bases
ATGACGAAGATCAATCTGGTCGCTCTTGGTGGGGTACGTGAAAACGGAAAAAACATGTACGCCGTCGAAGTTGACGACCA
AATTTTTGTATGCGATTTTGGGTTAAAATACCCTGATAATGAGTTACTTGGCATTGATGTTGTTATCCCTGATTTTAGTT
ATTTAACTGAAAATGCTGATCGGATTGCCGGGATTTTCCTGAGCCACGGACATGCGGATGCGGTTGGTGCCTTACCATAT
TTTTTGGTGGAACATCCTGTGCCAGTTTTTGGCTCGGAATTGACGATCGCGATGGCCAAGGTATTCATGCAACATGATGC
TCAGGCTAAAAAGTTCAAAGACTTTCATGTGATTGATGAGAAGTCGGTCATTGATTTTGGCGATGTGTCTGTCTCCTTCT
TTAGGACAACACATAGTATTCCCGGATCGTTGGGGATCGATATTGAAACCAGCGAAGGTCAGATTGTTTATACCGGTGAT
TTCAAATTTGACCCCAGTGCCACACCGATGTATCAAACTGATTGGGCGCGCTTGGCACAGATTGGGAATAAAAAGGTATT
GGCCTTGCTTTCGGATTCGGCCAATGCGGAATCTCCTTATCCAAATGCTAATGAACATGAAATTTATGATCACATTAAAG
AAACATTCGAGTATCAGGATGGCCGGATCATTGTTGCCGGTGTTGCCAGCAACATTCAGCGCATTCAGCAGGTTATTAAT
GCGGCCGCTTCGCTCGGACGACGCGTCGTTTTGACCGGCCGAGATGTTGAAAAAGTAGTCAAGACTGCAATTCGCATGGA
CTACATCAAGCTGCCGAATGAGGACGTCCTTGCTAAAACCAAGGAACTCAAAGCGCTTGCCCCAGAAAAAACGGTTATTT
TGGAAACTGGTCGTATGGGTGAACCGATGAAGTCCTTGCAACGCATGGCGACTTCTCGGCATCGTTTGATTCACATTCAT
GAAGGTGATTTAGTCTTTATTACGACCACCATCGCCCATGCCATGGAAACCATGGCAGCACGTACGAAAGACATGATTTA
TCGTGCTGGCGGAGATGTGAAAGTGCTTGGGGATGATATTCATTCATCTGGCCACGCCTACAAAAACGATCTTCAGCTTA
TGATCGACTTGTTAAAACCTCAATATCTTGTGCCAGTGCAAGGCGAATACCGTCTGATGGCTGCTCACGCGGAGATTGCG
CATGAAGCCGGTATCCCAACTGCCAATATCTTTATTGTTGGAATGGGCGACATTTTACGTTATGAAAAAGGTAAAATGAC
TGCATCGGGTCATGTTAATGCAGGTAACACCATGATTGACGGGATCGGTGTCGGTGATATTGGCAATATCGTTTTACGAG
ATCGTAAAATGCTTGCGGAAGACGGCATTTTCATTGCAGTTGTGACGATTGATCGCAAGAAAAAACGCGTCGTATCAAAG
CCGAAAGTCACGAGTCGCGGATTCGTTTATCTGAAGACCAGTCGTGATCTGCTTGCCGAAAGCGGCACACTAGTGACTGA
TACGGTCCAAAAGAACTTGGACAACAAAGAATTCGACTGGACACATTTGAAGCAGGATGTCCGCGATAAACTTAGTCGTT
TTCTGTTTGAACAGACGAAACGCCGCCCAGTTATCCTGCCGGTCATTATGGAAGTTAATCAAAATAGCGCCAAGCGCCAA
TAA

Upstream 100 bases:

>100_bases
TTCTGTCATGTGGTACACTTGTATAAGAATTTATTCGGCGGAAGCGGGTTTGAGTGATCATCATTGCCGCGCTTCCATAA
ATTAACCACGAGGTGAAACC

Downstream 100 bases:

>100_bases
TCAAAAAGAAAATTCGGATCACCATTTCCGGATTTTTTATTTTTGCAGTGATGACACGCTTTCTACAGCACGACAGGAGG
GTTCTTATGGCAAAAATGGT

Product: metallo-beta-lactamase superfamily hydrolase

Products: NA

Alternate protein names: RNase J2 [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MTKINLVALGGVRENGKNMYAVEVDDQIFVCDFGLKYPDNELLGIDVVIPDFSYLTENADRIAGIFLSHGHADAVGALPY
FLVEHPVPVFGSELTIAMAKVFMQHDAQAKKFKDFHVIDEKSVIDFGDVSVSFFRTTHSIPGSLGIDIETSEGQIVYTGD
FKFDPSATPMYQTDWARLAQIGNKKVLALLSDSANAESPYPNANEHEIYDHIKETFEYQDGRIIVAGVASNIQRIQQVIN
AAASLGRRVVLTGRDVEKVVKTAIRMDYIKLPNEDVLAKTKELKALAPEKTVILETGRMGEPMKSLQRMATSRHRLIHIH
EGDLVFITTTIAHAMETMAARTKDMIYRAGGDVKVLGDDIHSSGHAYKNDLQLMIDLLKPQYLVPVQGEYRLMAAHAEIA
HEAGIPTANIFIVGMGDILRYEKGKMTASGHVNAGNTMIDGIGVGDIGNIVLRDRKMLAEDGIFIAVVTIDRKKKRVVSK
PKVTSRGFVYLKTSRDLLAESGTLVTDTVQKNLDNKEFDWTHLKQDVRDKLSRFLFEQTKRRPVILPVIMEVNQNSAKRQ

Sequences:

>Translated_560_residues
MTKINLVALGGVRENGKNMYAVEVDDQIFVCDFGLKYPDNELLGIDVVIPDFSYLTENADRIAGIFLSHGHADAVGALPY
FLVEHPVPVFGSELTIAMAKVFMQHDAQAKKFKDFHVIDEKSVIDFGDVSVSFFRTTHSIPGSLGIDIETSEGQIVYTGD
FKFDPSATPMYQTDWARLAQIGNKKVLALLSDSANAESPYPNANEHEIYDHIKETFEYQDGRIIVAGVASNIQRIQQVIN
AAASLGRRVVLTGRDVEKVVKTAIRMDYIKLPNEDVLAKTKELKALAPEKTVILETGRMGEPMKSLQRMATSRHRLIHIH
EGDLVFITTTIAHAMETMAARTKDMIYRAGGDVKVLGDDIHSSGHAYKNDLQLMIDLLKPQYLVPVQGEYRLMAAHAEIA
HEAGIPTANIFIVGMGDILRYEKGKMTASGHVNAGNTMIDGIGVGDIGNIVLRDRKMLAEDGIFIAVVTIDRKKKRVVSK
PKVTSRGFVYLKTSRDLLAESGTLVTDTVQKNLDNKEFDWTHLKQDVRDKLSRFLFEQTKRRPVILPVIMEVNQNSAKRQ
>Mature_559_residues
TKINLVALGGVRENGKNMYAVEVDDQIFVCDFGLKYPDNELLGIDVVIPDFSYLTENADRIAGIFLSHGHADAVGALPYF
LVEHPVPVFGSELTIAMAKVFMQHDAQAKKFKDFHVIDEKSVIDFGDVSVSFFRTTHSIPGSLGIDIETSEGQIVYTGDF
KFDPSATPMYQTDWARLAQIGNKKVLALLSDSANAESPYPNANEHEIYDHIKETFEYQDGRIIVAGVASNIQRIQQVINA
AASLGRRVVLTGRDVEKVVKTAIRMDYIKLPNEDVLAKTKELKALAPEKTVILETGRMGEPMKSLQRMATSRHRLIHIHE
GDLVFITTTIAHAMETMAARTKDMIYRAGGDVKVLGDDIHSSGHAYKNDLQLMIDLLKPQYLVPVQGEYRLMAAHAEIAH
EAGIPTANIFIVGMGDILRYEKGKMTASGHVNAGNTMIDGIGVGDIGNIVLRDRKMLAEDGIFIAVVTIDRKKKRVVSKP
KVTSRGFVYLKTSRDLLAESGTLVTDTVQKNLDNKEFDWTHLKQDVRDKLSRFLFEQTKRRPVILPVIMEVNQNSAKRQ

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 62325; Mature: 62193

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKINLVALGGVRENGKNMYAVEVDDQIFVCDFGLKYPDNELLGIDVVIPDFSYLTENAD
CCEEEEEEECCEEECCCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEECCHHHHHCCCH
RIAGIFLSHGHADAVGALPYFLVEHPVPVFGSELTIAMAKVFMQHDAQAKKFKDFHVIDE
HEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEECC
KSVIDFGDVSVSFFRTTHSIPGSLGIDIETSEGQIVYTGDFKFDPSATPMYQTDWARLAQ
CCEEEECCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCEEECCCCCCCCCHHHHHHHH
IGNKKVLALLSDSANAESPYPNANEHEIYDHIKETFEYQDGRIIVAGVASNIQRIQQVIN
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
AAASLGRRVVLTGRDVEKVVKTAIRMDYIKLPNEDVLAKTKELKALAPEKTVILETGRMG
HHHHCCCEEEEECCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCCEEEEECCCCC
EPMKSLQRMATSRHRLIHIHEGDLVFITTTIAHAMETMAARTKDMIYRAGGDVKVLGDDI
CHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
HSSGHAYKNDLQLMIDLLKPQYLVPVQGEYRLMAAHAEIAHEAGIPTANIFIVGMGDILR
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEHHHHHHHCCCCEEEEEEEECHHHHE
YEKGKMTASGHVNAGNTMIDGIGVGDIGNIVLRDRKMLAEDGIFIAVVTIDRKKKRVVSK
ECCCCEEECCCCCCCCEEEECCCCCCCCCEEECCCHHHHCCCEEEEEEEECCHHHHHCCC
PKVTSRGFVYLKTSRDLLAESGTLVTDTVQKNLDNKEFDWTHLKQDVRDKLSRFLFEQTK
CCCCCCCEEEEECCHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RRPVILPVIMEVNQNSAKRQ
CCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TKINLVALGGVRENGKNMYAVEVDDQIFVCDFGLKYPDNELLGIDVVIPDFSYLTENAD
CEEEEEEECCEEECCCEEEEEEECCEEEEEECCCCCCCCCEEEEEEEECCHHHHHCCCH
RIAGIFLSHGHADAVGALPYFLVEHPVPVFGSELTIAMAKVFMQHDAQAKKFKDFHVIDE
HEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEEECC
KSVIDFGDVSVSFFRTTHSIPGSLGIDIETSEGQIVYTGDFKFDPSATPMYQTDWARLAQ
CCEEEECCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCEEECCCCCCCCCHHHHHHHH
IGNKKVLALLSDSANAESPYPNANEHEIYDHIKETFEYQDGRIIVAGVASNIQRIQQVIN
CCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
AAASLGRRVVLTGRDVEKVVKTAIRMDYIKLPNEDVLAKTKELKALAPEKTVILETGRMG
HHHHCCCEEEEECCCHHHHHHHHHHHHHEECCCHHHHHHHHHHHHCCCCCEEEEECCCCC
EPMKSLQRMATSRHRLIHIHEGDLVFITTTIAHAMETMAARTKDMIYRAGGDVKVLGDDI
CHHHHHHHHHCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHEECCCCEEEEECCC
HSSGHAYKNDLQLMIDLLKPQYLVPVQGEYRLMAAHAEIAHEAGIPTANIFIVGMGDILR
CCCCCCHHHHHHHHHHHHCCCEEEECCCCEEEEEEHHHHHHHCCCCEEEEEEEECHHHHE
YEKGKMTASGHVNAGNTMIDGIGVGDIGNIVLRDRKMLAEDGIFIAVVTIDRKKKRVVSK
ECCCCEEECCCCCCCCEEEECCCCCCCCCEEECCCHHHHCCCEEEEEEEECCHHHHHCCC
PKVTSRGFVYLKTSRDLLAESGTLVTDTVQKNLDNKEFDWTHLKQDVRDKLSRFLFEQTK
CCCCCCCEEEEECCHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
RRPVILPVIMEVNQNSAKRQ
CCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA