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The map label for this gene is xpt [H]

Identifier: 116494616

GI number: 116494616

Start: 1101797

End: 1102441

Strand: Direct

Name: xpt [H]

Synonym: LSEI_1117

Alternate gene names: 116494616

Gene position: 1101797-1102441 (Clockwise)

Preceding gene: 116494615

Following gene: 116494617

Centisome position: 38.06

GC content: 44.81

Gene sequence:

>645_bases
GTGTTGTTCCACACTGATTTTTATGGTAAGCTTGTTGAAAATTTACAATTAAAAGGAGTGCTTGTGGTGAAATTACTGGA
AGACCGGATCAAAAAGGATGGCCAAGTAATAGGAACAGATGTCTTGAAGGTGGATAACTTTTTGAATCATCAGGTCGATC
CTGATTTAATGGCAGATCTCGGTCATGAATTCTACCGGCGCTTCAGCAATGAGCCGATCACCAAAATTCTGACGGTTGAA
AGTTCCGGCATTGCGCCAGCGATTGCAACGGCAATGGAGTTTCACAAGCCGTTGGTTTTTGCTCGTAAGCATAAGAGCTT
GACTTTAAAAGATCATCTTTACACAGCTACGGTCTATTCGTTCACTAAAAAGACCTCCAATGAGATCGCTATCTCTCGCA
AGTTCCTTTCAGCCGATGACAATGTTTTGATCATTGATGATTTTCTTGCCAACGGTCAGGCGGTCGAAGGCTTGATGGAT
ATCATTGCGCAGGCTGGTGCGACACTGAGCGGTGTGGGGATTGTGATCGAGAAGACTTTCCAAAAAGGCCGCAAGTTGCT
TGATGAAAAGCACGTTCGCGTCGAATCATTGGCGCGCATCAATGCATTTGAAAATGGTCAGGTCATCTTTGCGCCGGAGG
ATTAG

Upstream 100 bases:

>100_bases
AATCCTCGTTATTTTGACTTTTTAAAGCCGAATCACGGGGATTTTACTTATTCTTTTGATGAAAGCGGCTTCGCGTGTTT
GTTCGGGAATTAGCGTGATT

Downstream 100 bases:

>100_bases
CCCACGATGAAGAATAAAGCGATTTCGAATCCTAAAGCAGCCGCATTGGGACTGCAGCATTTGCTGGCGATGTATTCCGG
TTCGGTGTTAGTACCAATTC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MLFHTDFYGKLVENLQLKGVLVVKLLEDRIKKDGQVIGTDVLKVDNFLNHQVDPDLMADLGHEFYRRFSNEPITKILTVE
SSGIAPAIATAMEFHKPLVFARKHKSLTLKDHLYTATVYSFTKKTSNEIAISRKFLSADDNVLIIDDFLANGQAVEGLMD
IIAQAGATLSGVGIVIEKTFQKGRKLLDEKHVRVESLARINAFENGQVIFAPED

Sequences:

>Translated_214_residues
MLFHTDFYGKLVENLQLKGVLVVKLLEDRIKKDGQVIGTDVLKVDNFLNHQVDPDLMADLGHEFYRRFSNEPITKILTVE
SSGIAPAIATAMEFHKPLVFARKHKSLTLKDHLYTATVYSFTKKTSNEIAISRKFLSADDNVLIIDDFLANGQAVEGLMD
IIAQAGATLSGVGIVIEKTFQKGRKLLDEKHVRVESLARINAFENGQVIFAPED
>Mature_214_residues
MLFHTDFYGKLVENLQLKGVLVVKLLEDRIKKDGQVIGTDVLKVDNFLNHQVDPDLMADLGHEFYRRFSNEPITKILTVE
SSGIAPAIATAMEFHKPLVFARKHKSLTLKDHLYTATVYSFTKKTSNEIAISRKFLSADDNVLIIDDFLANGQAVEGLMD
IIAQAGATLSGVGIVIEKTFQKGRKLLDEKHVRVESLARINAFENGQVIFAPED

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 23900; Mature: 23900

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHTDFYGKLVENLQLKGVLVVKLLEDRIKKDGQVIGTDVLKVDNFLNHQVDPDLMADL
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHCCCCCHHHHHHH
GHEFYRRFSNEPITKILTVESSGIAPAIATAMEFHKPLVFARKHKSLTLKDHLYTATVYS
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHEECCCCCEEEHHHHHHHHHHH
FTKKTSNEIAISRKFLSADDNVLIIDDFLANGQAVEGLMDIIAQAGATLSGVGIVIEKTF
HHHCCCCHHEEEHHEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
QKGRKLLDEKHVRVESLARINAFENGQVIFAPED
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
>Mature Secondary Structure
MLFHTDFYGKLVENLQLKGVLVVKLLEDRIKKDGQVIGTDVLKVDNFLNHQVDPDLMADL
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHCCCCCHHHHHHH
GHEFYRRFSNEPITKILTVESSGIAPAIATAMEFHKPLVFARKHKSLTLKDHLYTATVYS
HHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCHHEECCCCCEEEHHHHHHHHHHH
FTKKTSNEIAISRKFLSADDNVLIIDDFLANGQAVEGLMDIIAQAGATLSGVGIVIEKTF
HHHCCCCHHEEEHHEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
QKGRKLLDEKHVRVESLARINAFENGQVIFAPED
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA