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The map label for this gene is comGA [H]

Identifier: 116494526

GI number: 116494526

Start: 1010606

End: 1011472

Strand: Direct

Name: comGA [H]

Synonym: LSEI_1023

Alternate gene names: 116494526

Gene position: 1010606-1011472 (Clockwise)

Preceding gene: 116494525

Following gene: 116494527

Centisome position: 34.91

GC content: 50.52

Gene sequence:

>867_bases
ATGCAATCGGTGAATAAGCTTTTGACAATTGCGCTGGAAAAGGGTGCTAGCGATATTTACTATTTGCCTAGTCCGCAAGG
TTATTTGATTCGCCTACGAGTACCGACGGGCTTGGTAACAATCGCCGAGCGAGACAGCAAACGTGGGCAGCAAGAAATTA
ATTACTTGAAATTTATGGCGGGCATGAATGTTGCCGAACATCGCCGCGTTCAATTGGGAGCCTTTTATCAAAAGGAATCA
GCAGCTTTTTTACGGTTAAGTTCAGTGGCTGACTTTCGCGGTGGTGAATCACTGGTAGTTCGCATAATCAAAGGCATTCC
AGATGCTGCAGGCGCACGTCATCTGTTAGATCGTCTGTTGGGTATTTTACTGCAGAAACGCGGCATGCTGACCCTAGCTG
GGCCGACTGGGTCAGGAAAAACGACATTACTCTATCAGTTAGCGACGCGTTTGGCGGAATCACGAATGGTCTTGTCGATC
GAGGATCCAGTTGAGATCAATCAGCCGCAATTCTTACAGTTGCAAGTCAATCCGGAGGCAGACATGACCTATCCGCAATT
ACTGAAGGCGGCGCTGCGCCATCGACCAGACGTCTTGCTGATTGGAGAAATTCGTGATCGACAAACAGCGCAAAGTGCTT
GCGAAGCGGCGATTAGCGGTCACATTGTCCTAGCGACCGTGCATGCCCGATCAGCGGCGGATACACCCTTAAGGCTGAGC
AGTTTTGGCTTGTCGGATGAGTTAGTAGCGGCGGCATTGACGGCGAGTGCGGCGATCAGTTTGCAGTATCGGCCAATGAT
TCACCCGGTGGCGGAAGTCGTGGTTTTCAAGCAAGTAGGACAAGCTGATCAGGAGGTGGTTTCGTGA

Upstream 100 bases:

>100_bases
AGACGAGGGGAAATCCTCGTCTTTTTTTCTGCCCAAAATAGTAAAGAGGACGGGGTGATATATGACGCTCGCGAACTCTT
TTAATACAGGGGGAAAAACG

Downstream 100 bases:

>100_bases
GCATGTCGCTGGTGATTCAGGAACGGTTTTGCCGTCAAAGCGCTGCGTTAATTGCTGCTGGTTTTAGTTTGCCGGATGTG
TTTGCTTATTTGCGTGTGAG

Product: Type II secretory pathway/competence component, ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MQSVNKLLTIALEKGASDIYYLPSPQGYLIRLRVPTGLVTIAERDSKRGQQEINYLKFMAGMNVAEHRRVQLGAFYQKES
AAFLRLSSVADFRGGESLVVRIIKGIPDAAGARHLLDRLLGILLQKRGMLTLAGPTGSGKTTLLYQLATRLAESRMVLSI
EDPVEINQPQFLQLQVNPEADMTYPQLLKAALRHRPDVLLIGEIRDRQTAQSACEAAISGHIVLATVHARSAADTPLRLS
SFGLSDELVAAALTASAAISLQYRPMIHPVAEVVVFKQVGQADQEVVS

Sequences:

>Translated_288_residues
MQSVNKLLTIALEKGASDIYYLPSPQGYLIRLRVPTGLVTIAERDSKRGQQEINYLKFMAGMNVAEHRRVQLGAFYQKES
AAFLRLSSVADFRGGESLVVRIIKGIPDAAGARHLLDRLLGILLQKRGMLTLAGPTGSGKTTLLYQLATRLAESRMVLSI
EDPVEINQPQFLQLQVNPEADMTYPQLLKAALRHRPDVLLIGEIRDRQTAQSACEAAISGHIVLATVHARSAADTPLRLS
SFGLSDELVAAALTASAAISLQYRPMIHPVAEVVVFKQVGQADQEVVS
>Mature_288_residues
MQSVNKLLTIALEKGASDIYYLPSPQGYLIRLRVPTGLVTIAERDSKRGQQEINYLKFMAGMNVAEHRRVQLGAFYQKES
AAFLRLSSVADFRGGESLVVRIIKGIPDAAGARHLLDRLLGILLQKRGMLTLAGPTGSGKTTLLYQLATRLAESRMVLSI
EDPVEINQPQFLQLQVNPEADMTYPQLLKAALRHRPDVLLIGEIRDRQTAQSACEAAISGHIVLATVHARSAADTPLRLS
SFGLSDELVAAALTASAAISLQYRPMIHPVAEVVVFKQVGQADQEVVS

Specific function: Required for uptake of DNA by competent cells [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1786296, Length=260, Percent_Identity=36.1538461538462, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1789723, Length=262, Percent_Identity=33.206106870229, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI87082188, Length=186, Percent_Identity=35.4838709677419, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 31420; Mature: 31420

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVNKLLTIALEKGASDIYYLPSPQGYLIRLRVPTGLVTIAERDSKRGQQEINYLKFMA
CCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
GMNVAEHRRVQLGAFYQKESAAFLRLSSVADFRGGESLVVRIIKGIPDAAGARHLLDRLL
CCCHHHHCEEHEHHHHCCCCHHHEEEHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
GILLQKRGMLTLAGPTGSGKTTLLYQLATRLAESRMVLSIEDPVEINQPQFLQLQVNPEA
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCC
DMTYPQLLKAALRHRPDVLLIGEIRDRQTAQSACEAAISGHIVLATVHARSAADTPLRLS
CCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEH
SFGLSDELVAAALTASAAISLQYRPMIHPVAEVVVFKQVGQADQEVVS
HCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MQSVNKLLTIALEKGASDIYYLPSPQGYLIRLRVPTGLVTIAERDSKRGQQEINYLKFMA
CCCHHHHHHHHHHCCCCCEEECCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
GMNVAEHRRVQLGAFYQKESAAFLRLSSVADFRGGESLVVRIIKGIPDAAGARHLLDRLL
CCCHHHHCEEHEHHHHCCCCHHHEEEHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
GILLQKRGMLTLAGPTGSGKTTLLYQLATRLAESRMVLSIEDPVEINQPQFLQLQVNPEA
HHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCC
DMTYPQLLKAALRHRPDVLLIGEIRDRQTAQSACEAAISGHIVLATVHARSAADTPLRLS
CCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEH
SFGLSDELVAAALTASAAISLQYRPMIHPVAEVVVFKQVGQADQEVVS
HCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2507524; 8969508; 9384377; 9422590; 9723928 [H]